80578.m00126

Species: T.vaginalis
Alias: 80578.m00126, TvagK0003
External Links:
Annotation:

Classification

Group: CAMK
Family: CAMKL
Subfamily: CAMKL-Tvag2

Sequence

Name Sequence Type Origin Length Description Download
80578.m00126.AA Protein None 424 None Fasta, JSON
80578.m00126.kin_dom Protein Kinase Domain None 252 None Fasta, JSON

Protein domain

Protein domains of 80578.m00126.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 80578.m00126.AA CAMK 21-267 24 1.6e-109 354.19 In-house 1-425 (425) Show / Hide
Range on Protein: 21-267
Range on HMM: 1-425/425
Sequence Identity: 24% (105 aa)

TIGEGAFSIVKLVVKEQNG------------QYYACKIIPRAKLE--------------------------GSIRTRFELEIRINQQ-------MRHPGV
|.|.|.|..|||..  ...            | .|.|||.. ||                           .. | ... ||.| ..       ..|| .
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

VALIDLFKDDFN-------------------YYIIM---EFCPNGEL----FEYIVQH---------------GKLSERECKPLFYQLTSTIQFIHNMNV
. |.. . |...                   .|..|   |.|..|||    |.|||.|               |...|||.. .| |. | ....|..|.
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNI

CHRDLKPENILID-RF----------------GRLKISDFGLSRFMGP------------------------NCIVSTSCGSPCYAS-PECISG------
.||||||||||.| ..                . .||.|||..... |                        .   .|.||.|.|.. || ..|      
VHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNM

-------KPYNAKTSDVWSLGVIFYAMSSGLLPWTKR-------------NQTELYQQISTGDYK-IPNHLSP-----------------------ALAD
       |||  . .|.||.||| |.| .| .|.                |. ||...| .|.|  .| ..||                          |
QNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECKD

LVRKMLTVDLNKRITIAQILDHDFF
|.||||.|| .||.||.|.|.| ..
LIRKMLQVDPEKRMTIEQCLNHPWM

Kinase 80578.m00126.AA AMPK 16-267 43 5.2e-107 318.72 In-house 1-254 (254) Show / Hide
Range on Protein: 16-267
Range on HMM: 1-254/254
Sequence Identity: 43% (111 aa)

FIFKGTIGEGAFSIVKLVVKEQNGQYYACKIIPRAKLEG-SIRTRFELEIRINQQMRHPGVVALIDLF-KDDFNYYIIMEFCPNGELFEYIVQHGKLSER
.| . |||||.|  ||. . .. |.. | ||. . |. . .   | . ||.| . .||| .. | .   .     ...||. ..||||.|||.||.|.||
YIIGKTIGEGTFGKVKMGTHILTGEKVAIKILNKQKIKDQDMVERIQREIHILKLFRHPHIIQLYEVIIETPTDIFMVMEYVSGGELFDYIVKHGRLQER

ECKPLFYQLTSTIQFIHNMNVCHRDLKPENILIDRFGRLKISDFGLSRFMGPNCIVSTSCGSPCYASPECISGKPYNAKTSDVWSLGVIFYAMSSGLLPW
| . .| |  | .  .|. .. ||||||||.|.|   ..|| |||||  |  .   .|.|||||||.|| ||||.|.    |.|| ||| |||  | || 
EACRFFQQIISGVEYCHRHMIVHRDLKPENLLLDHNKNIKIVDFGLSNMMKDGEFLKTACGSPCYAAPEMISGKLYCGPEVDIWSCGVILYAMLCGYLPF

TKRNQTELYQQISTGDYKIPNHLSPALADLVRKMLTVDLNKRITIAQILDHDFF
   |...||. |  |.|.|| .|||  .||...||.|| .||||| .|  |..|
DDENTPTLYKKIKNGEYYIPKFLSPEAKDLIKHMLQVDPMKRITIHDIRNHPWF

Kinase 80578.m00126.AA CAMKL 16-267 34 6e-102 326.14 In-house 1-297 (297) Show / Hide
Range on Protein: 16-267
Range on HMM: 1-297/297
Sequence Identity: 34% (102 aa)

FIFKGTIGEGAFSIVKLVVKEQN-GQYYACKIIP--RAKLEGSIRTR-----------FELEIRINQQMR---HPGVVALIDLFKDDFN------YYIIM
...  |.|.|.|. ||| . ... |. .| |||   .....  .. .            . ||.| ....   || .. | . . .. .      .|..|
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVM

EFCPNGE--LFEYIVQH----GKLSERECKPLFYQLTSTIQFIHNMNVCHRDLKPENILIDRFG--RLKISDFGLSRFMGP-----NCIVSTSCGSPCYA
| |..||  ||.|||.|    |...|.|.. .| |. | ....|.....|||.||||||.|  |   .||.|||.| .. |     .   .|.||||.|.
EYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPYM

SPECISG--KPYNAKTSDVWSLGVIFYAMSSGLLPWTKR--------NQTELYQQISTGDYKIP--NHLSPALADLVRKMLTVDLNKRITIAQILDHDFF
.|| ..|  |||...  |.||.||| |||  | ||.           |. .|| .| .| |..|  .|.|  . || ||||.|. .||.|| ||. | ..
APEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMNHPWM





S_TKc 80578.m00126.AA S_TKc 16-267 31 2.3e-97 330.68 SMART 1-231 (231) Show / Hide
Range on Protein: 16-267
Range on HMM: 1-231/231
Sequence Identity: 31% (84 aa)

FIFKGTIGEGAFSIVKLVVKEQNGQYYACKIIPRAKLEGSIRTRFELEIRINQQMRHPGVVALIDLFKDDFNYYIIMEFCPN--GELFEYIVQHGK----
. .  .||.|||. |.....   |...|.|||.          ... ||.| .. .|| .| |.| | |  ..|..||.|..  |.||.||...|.    
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLR

--LSERECKPLFYQLTSTIQFIHNMNVCHRDLKPENILIDRFGRLKISDFGLSRFMGPNCIVSTSCGSPCYASPECISGKPYNAKTSDVWSLGVIFYAMS
  ..| ... ..||. . ....|.....||||||||||.|.  ..||.||||.|..      .| ||.| | .|| .   .|. . .|.||.|.|.| | 
FPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEML

SGLLPWTKRNQTELYQQISTGDYKIPNHLSPALADLVRKMLTVDLNKRITIAQILD-------HDFF
.|  |.   .. .....|           || . |..||.|..| .||.|. ..|        | .|
CGYPPFP--QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF

Kinase 80578.m00126.AA AGC 16-267 22 5.1e-93 240.16 In-house 1-395 (395) Show / Hide
Range on Protein: 16-267
Range on HMM: 1-395/395
Sequence Identity: 22% (88 aa)

FIFKGTIGEGAFSIVKLVVKE------QNGQYYACKIIPRAK--------LEGSIRTR--------FELEIRINQQMR----------HPGVVA-LIDLF
| |. .||.|.|. | || |       ..|.|||.|..  ..         .  . |         .  | .| ....          || .|  |   |
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF

KDDFN--YYIIMEFCP---------NG-ELFEYIV---QHGKLSERECKPLFYQ-------LTSTIQFIHN-MNVCHRD-LKPENILIDRFGRLKISDFG
.|. .   |..||..|          | ||| ..    . |...| ...  . .       ... ....|. |.. ||| |||||||.|. | .|..|||
QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG

LSRFMGPNC---------------------------------------------------IVSTSCG--SPCYASPECISGKPYNAKTSDVWS--LGVIF
|.  .  ..                                                     .| ||  .| | .|| .       |. | ||  ||...
LCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL-----YGKACDWWSFGLGCLM

YAMSSGLLPWTKRN----------QTELYQQIS------TGDYKIP----------NHLSPALADLVRKMLTVDLNKRIT----------IAQILDHDFF
| | .|. | .  |          . |..|.|       . . |.|           ..|| . ||..|.|..| .||..          . .| .| .|
YEMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNHPWF





Kinase 80578.m00126.AA MARK 16-267 36 5.8e-87 284.3 In-house 1-262 (262) Show / Hide
Range on Protein: 16-267
Range on HMM: 1-262/262
Sequence Identity: 36% (96 aa)

FIFKGTIGEGAFSIVKLVVKEQNGQYYACKIIPRAKLEG-SIRTRFELEIRINQQMRHPGVVALIDLFK--DDFN-YYIIMEFCPNGELFEYIVQH--GK
. .. |||.|... |||..    |. .| ||... ||     .  .. ||.| ... || .. | . .   .  .  |.||| ...|||..||..|  |.
YKMLKTIGHGSYAKVKLACHKHTGRKVAIKIYEKFKLNDPQWMKNVMREIEIMKKLDHPNIIKLFHVIEQDTEQHQIYLIMEYASGGELYDYIKAHPNGR

LSERECKPLFYQLTSTIQFIHNMNVCHRDLKPENILIDRFG--RLKISDFGLSRFMGPNCIVSTSCGSPCYASPECISGKPYNAKTSDVWSLGVIFYAMS
|.|.|.. .| |. | ... |..|..|||.||||||||  |    ||.|||.|.   |..  .| ||.| |..|| ...|||...  |.|||||. |.| 
LHEEEARRIFRQIVSAVNYCHSKNIVHRDIKPENILIDENGNHNIKIIDFGFSICIPPGQKLNTFCGTPPYMAPEIFLKKPYDGPKVDIWSLGVVLYFMV

SGLLPWTKRN--QTELYQQISTGDYKIPNHLSPALADLVRKMLTVDLNKRITIAQILDHDFF
.| .|.   .  . |||..| .|.|.|| |.|. . .|....|||. ..|.|| .|. | ..
CGYFPFDGDTQDYKELYKKILRGKYDIPCHVSKECRNLIQRLLTVNPEERPTIEEIMKHPWM

Kinase 80578.m00126.AA Pkinase 16-267 31 4.3e-86 297.13 Pfam 1-293 (293) Show / Hide
Range on Protein: 16-267
Range on HMM: 1-293/293
Sequence Identity: 31% (92 aa)

FIFKGTIGEGAFSIVKLVVKEQNGQYYACKIIPRAKLEGSIRTRFEL--EIRINQQMRHPGVVALIDLFKDDFNYYIIMEFCPNG----ELFEYIV--QH
. ....||.|.|. |.. ..  .|. .|.|||.. . . . . .  .  ||.| . ..|| .| |.| | |. ..|..||.|..|    .||.||   .|
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

GKL--SERECKPLFYQLTSTIQFIHNMNVCHRDLKPENILIDRFGRL----KISDFGLSRF--MGPNCIVSTSCGSPCYASPECISGKPYNAKTSDVWSL
|..  ||.|||  .||. . ....|.|...||||||||||||. | .    ||.||||...    .|   .| ||.| |..|| | | .|  . .|.||.
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSC

GVIFYAMSSGLLPWTKR------NQTELYQQISTGDYKIPNHLS---------------------PALADLVRKMLTVDLNKRITIAQILDHDFF
|.|.| | .| .|.  .      .| .....|  .... .   .                     ... |.....|..| .||.|..||| |..|
GCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF

Kinase 80578.m00126.AA ULK 16-267 27 1.4e-81 277.33 In-house 1-329 (329) Show / Hide
Range on Protein: 16-267
Range on HMM: 1-329/329
Sequence Identity: 27% (90 aa)

FIFKGTIGEGAFSIVKLVVKEQN----GQYYACKIIPRAKLEGSIRTR--------FELEIRINQQMR--------HPGVVALIDLFKDD--FNYYIIME
.. .  .|.|.|  |    ....    ....|||.|.. |.  .   .        .. ||.| ...         || .| |.| |...   |.|||||
YCLNHCLGKGSFGKVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYIIME

FCPNGELFEYIVQHGK----------LSERECKPLFYQLTSTIQFIHNMNVCHRDLKPENILIDRF------------GRLKISDFGLSRFMGPN-----
.|. | |..|| ...|          ||| |..  |.|. .  ...| .|. |||.||.||||.              |.|||.|||.....  .     
YCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNDNMEQQ

CIVSTS-----CGSPCYASPECIS----GKPYNAKTSDVWSLGVIFYAMSSGLLP---WTKRNQT-----ELYQQ-------ISTGDYKIP-----NHLS
 .....     ||.| | .|. ..    .|||. ...|.||||.||| |  |  |   | .. |      .|...       | .   ..|     ...|
MMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAW-FNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDGNDPQIS

PALADLVRKMLTVDLNKRITIAQILDHDFF
| . || |.||..| ..||.. ....| .|
PECKDLIRRMLQYDEKDRISWEELFNHPWF

Kinase 80578.m00126.AA ULK 16-267 28 1.5e-81 277.24 In-house 1-324 (324) Show / Hide
Range on Protein: 16-267
Range on HMM: 1-324/324
Sequence Identity: 28% (94 aa)

FIFKGTIGEGAFS-IVKLVVKEQN---GQYYACKIIPRAKLEGSIRT--------RFELEIRINQQMR---HPG--VVALIDLFKDD--FNYYIIMEFCP
.. .  .|.|.|   |    ....   .||.|||.|.. |.  .            .. ||.| ...    ||   .| |.| |...   |.|||||.|.
YCLNHCLGKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNHHIVKLYDWFETSNHNNIYIIMEYCN

NGELFEYIVQHGK---------LSERECKPLFYQLTSTIQFIHNMNVCHRDLKPENILIDRF------------GRLKISDFGLSRFMGPNCIVSTSC--
 | |..|| ...|         ||| |..  |.|. .  ...|..|. |||.||.||||               |.|||.|||....   |    . |  
GGDLEQYIKKNKKLPETEEKKRLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNNNMEQQMCQT

--------GSPCYASPECIS----GKPYNAKTSDVWSLGVIFYAMSSGLLP---WTKRNQT----ELYQQ-------ISTGDYKIP-----NHLSPALAD
        |.| | .|. ..    .|||. . .|.||||.||| |  |  |   | ...|     .| ..       | .   ..|     ...|| . |
CVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKYPFFSW-FNDQYLYIQKLINNGKEQQIYIKNQPIQFPKPPKDPKISPECKD

LVRKMLTVDLNKRITIAQILDHDFF
| |.||..| ..||.. .|..| .|
LIRRMLQYDEKDRISWEEIFNHPWF

Kinase 80578.m00126.AA Ciliate-E2 16-267 24 4.2e-81 275.76 In-house 1-365 (365) Show / Hide
Range on Protein: 16-267
Range on HMM: 1-365/365
Sequence Identity: 24% (91 aa)

FIFKGTIGEGAFSIVKLV-VKEQNGQY-----------------YACKIIPRAKLEGSIRTRFELEIRINQQMR----------------HPGVVALIDL
..|   ||.|.|..|... |.... |.                 .. ||.    .. .    .. ||.|.....                || .. ... 
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

FK--DDFNYYIIMEFCPNGELFEYIVQH-----------GKLSERECKPLFYQLTS---------------TIQFIHNMN-VCHRDLKPENILIDRFGRL
|.  || |.|..||.|  |.||.|| ..           ....|.|.| ...|...                ....|. | ..|||.||||||.     .
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----I

KISDFGLSRFMGPN--------------------------------CIVSTSCGSPCYASPECISGKPYNA--------KTSDVWSLGVIFYAMSSGLLP
||.|||||..  ..                                 .. | ||.| | .|| ..||.|.         . .|.||||||.| | .| .|
KIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPP

WTKRNQTELYQQISTGDYKIP------------------NHLSPALADLVRK----MLTVDLNKRIT-IAQILDHDFF
.        .|||  .....|                  ...|.   || .|    || .| .|||| . |||.| .|
F--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF

Kinase 80578.m00126.AA Ciliate-E2-Unclassified 16-267 26 4.6e-81 275.62 In-house 1-352 (352) Show / Hide
Range on Protein: 16-267
Range on HMM: 1-352/352
Sequence Identity: 26% (95 aa)

FIFKGTIGEGAFSIVKLVVKEQNGQYYACKIIPRAKLEGSIRTRF---------ELEIR--------------INQQMRHPGVVALIDLFKDDFNYYIIM
...  .||.|.|..|.........|||| |..  ..   .   ..         |....              | ... || .| ... |.|..| ||.|
YKIIKQIGQGGFGKVYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKDEIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIVM

EFCPNGELFEYIVQHGK-----------------LSERECK-----PLFYQLTSTIQFIHNMN-VCHRDLKPENILIDRFG---RLKISDFGLSRFMGPN
|.|..|.|..|| . .|                 ..|...|      .|.|. . ....|  | ..|||.||||||.|  |   ..||.|||.|.. . |
EYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQN

----------------CIVSTSCGSPCYA----SPECISGKPYNA---KTSDVWSLGVIFYAMSSGLLPWTKRNQTE----------------LYQQIST
                .. .| ||.|.|     .||.. |. |.    . .|.||||||.|.|  | .|   .|...                |||.|  
NNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNIKQ

GDYKIPN--------HLSPALADLVR----KMLTVDLNKRITIAQILDHDFF
.....|.        |.||  .|...    ||| ...|||||. ||| | .|
KNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF

Kinase 80578.m00126.AA QIK 16-267 33 2e-73 250.28 In-house 1-272 (272) Show / Hide
Range on Protein: 16-267
Range on HMM: 1-272/272
Sequence Identity: 33% (92 aa)

FIFKGTIGEGAFSIVKLVVKEQNGQYYACKIIPRAKLEGSIRTRFELEIRINQQMRHPGVVALIDLFKDDFNYYIIMEFCPNGELFEYIVQHGK------
.    ||| | | .|||       .  | ||| . .|. .  .. . |. |  ...|| .. | .    |   ||..|.|.|||.|.|...||.      
YDIERTIGKGNFAVVKLARHRITKTKVAIKIIDKSQLDEENLQKCYREVQIMKMLYHPHIIKLYQVMETDDMMYIVTEYCSNGEMFDYLCKHGRKGVKMV

--------------LSERECKPLFYQLTSTIQFIHNMNVCHRDLKPENILIDRFGRLKISDFGLSRFMGPNCIVSTSCGSPCYASPECISGKPYNAKTSD
              ..|.| .  | |. | ... |. |. ||||| ||||.|     || |||.| .  .    .| |||| || ||   || |.   .|
NSPDIGDQVLMGVPMAENEARRWFWQICSAVHYCHKRNIVHRDLKAENILLDNNMNIKIADFGFSNWFKQGQLLMTWCGSPPYAAPEMFEGKEYDGPKVD

VWSLGVIFYAMSSGLLPWTKRNQTELYQQISTGDYKIPNHLSPALADLVRKMLTVDLNKRITIAQILDHDFF
.||.||. |.. .| ||    . ..| | .  | ..||  .|  ...|.|.||.|| ..|.||.||. |   
IWSMGVVLYVLVCGALPFDGKTLQNLRQRVLSGKFRIPFFMSQDCEHLIRHMLVVDPEHRYTIMQICQHRWM

Kinase 80578.m00126.AA TyrKc 16-267 23 1.8e-16 43.74 SMART 1-280 (280) Show / Hide
Range on Protein: 16-267
Range on HMM: 1-280/280
Sequence Identity: 23% (69 aa)

FIFKGTIGEGAFSIVKLVVKEQNGQYYACKIIPRAKLEGSIRTRFELEIRINQQM--RHPGVVALIDLFKDD-------FNYYIIMEFCPNGELFEYIVQ
  .. ..||||| .| . .     .  | | .   .     |  |  |.||  .   .|| .|.|.    ..         ..|.||..|.| | .|.  
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRK

HGK-LSERECKPLFYQLTSTIQFIHNMNVCHRDLKPENILIDRFGRLKISDFGLSRFMGPN--------CIVSTS--CG---SPC-YASPECISGKPYNA
|.. |. ..     .|  .  ...| .|. ||||   |.|... .. |||||||||. .           .....  .|    |    .||||  . .. 
HRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTT

KTSDVWSLGVIFY-AMSSGLLPWTK-----RNQTELYQQISTGDY-KIPNH--------LSPALADLVRKMLTVDLNKRITIAQILDHDFF
| ||||| ||  .  .. |  |.        . .|..... .|.. ..| .         .... .. ..    | ..| | ..|  |..|
K-SDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF

Kinase 80578.m00126.AA Pkinase_Tyr 87-201 30 1.1e-08 30.03 Pfam 81-202 (270) Show / Hide
Range on Protein: 87-201
Range on HMM: 81-202/270
Sequence Identity: 30% (38 aa)

NYYIIMEFCPNGELFEYIVQH----GKLSERECKPLFYQLTSTIQFIHNMNVCHRDLKPENILIDRFGRLKISDFGLSRFM--GPNC-IVSTSCGSP-CY
..||.||..|.| | .|  .|    ..|.  .     .|  .  .. ...|  ||||   |.|... .  ||.||||.| .    .   .....  |   
QIYIVMEYMPHGDLLDYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKW

ASPECISGKPYNAKTSDVWSLGV
 .||||. . .. | ||||| ||
MAPECINYGKFTTK-SDVWSFGV