Gene 94173.m00229 (T.vaginalis)

94173.m00229

Species: T.vaginalis
Alias: 94173.m00229, TvagK0426
External Links:
Annotation:

Classification

Group: AGC
Family: NDR
Subfamily: NDR-Unclassified

Sequence

Name Sequence Type Origin Length Description Download
94173.m00229.AA Protein None 452 None Fasta, JSON
94173.m00229.kin_dom Protein Kinase Domain None 283 None Fasta, JSON

Protein domain

Protein domains of 94173.m00229.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 94173.m00229.AA AGC 83-365 28 8.70000000001e-143 371.81 In-house 1-395 (395) Show / Hide 
Range on Protein: 83-365
Range on HMM: 1-395/395
Sequence Identity: 28% (120 aa)

FEKIKIIGKGEYGDVYLVRDK------TDNKIYAMKIIQKSE-LIAKG--QLRNTLTE------------KDLLSRMD----------SKWSVQ-LIYAF
|| .|.|||| .| |||||.|      . .|.||||...|..  . |   ....|.||            .. |....          . . |. | |.|
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF

QDMYS--IYFVMEYLP---------GG-DLLTVLMCR-S--YLTLEETRFYIAE-------ILLAIREVHS-LGYIHCD-IKPDNILLTKDGHIRLSDYG
||     .||||||.|         || .|.. |. |    ... |..|||.||       |.||.   || .|.|| | .||.||||..||||.|.| |
QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG

LSTPLHRDE--------------------------NFVTILDEVEDVCRDPNSERKEQPLKSN---------HKKDAICSTVG--TPDYIAPEVLLKKPY
|.. . .|.                          |               . ..... .. |         .|.|   . .|  ||.|.|||.|    |
LCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTN---------------K-CNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL----Y

GPEVDLWS--LGAIMYEMLYGQPPYLA--------------DTAINII------HWKSTL------IFPKLKEISPEAVDLMKHLLC-NSKRRFT-----
|...| ||  ||..|||||.|.||. .              ..  .|.      .|| ..       ||. ...||||.||.|.||| . ..| .     
GKACDWWSFGLGCLMYEMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGND

-----IEDCMKHPFF
     .|. ..||.|
FGDKGAEEIKNHPWF
Kinase 94173.m00229.AA NDR 83-365 37 1.5e-124 386.26 In-house 1-350 (350) Show / Hide 
Range on Protein: 83-365
Range on HMM: 1-350/350
Sequence Identity: 37% (132 aa)

FEKIKIIGKGEYGDVYLVRDK-TDNKIYAMKIIQKSELIAKGQLRNTLTEKDLLSRMD--SKWSVQLIYAFQDMYSIYFVMEYLPGGDLLT---VLMCRS
||.||||||| .| |.||| | | ..||||||. ||| . | |. . ..|.| ..  |  ..| | | |.|||  ..|.||||.||||. |   .||   
FEIIKIIGKGAFGEVWLVRKKDT-GHIYAMKIMRKSEMMWKNQVAHVRAERDIMAEADNKNPWVVKLYYSFQDKQYLYLVMEYHPGGDMMTYCYLLMKMD

YLTLEETRFYIAEILLAIREVHSLGYIHCDIKPDNILLTKDGHIRLSDYGLSTP-----------------------LHRDENFVTILDEVEDVCRDPNS
..| ...||||||. .||  ||..|||| ||||||.|. ||||| |.| ||.|                          ..... . ..|..  ..  |.
IFTEDWARFYIAEMVCAIESVHKMGYIHRDIKPDNFLIDKDGHIKLTDFGLCTGGMIRRHWKQNKQKKPMTTYSTFHWTHNSWYYQNMKEHRPQDFMDNW

ERKEQPLKS-----------------------NHKKDAICSTVGTPDYIAPEVLLK-KPYGPEVDLWSLGAIMYEMLYGQPPYLAD----TAINIIHWKS
... .. |.                       ....    ||||||||.||||... . |....| ||||.|||||| |.|| ..|    |  .|..|| 
NSNPMNQKCKCHTQMKDQMKCNVKVLNNRSWKQNRRCLAYSTVGTPDYMAPEVFQQKTGYNQTCDWWSLGCIMYEMLVGYPPFCSDTPQETCMKIMNWKQ

TL-----IFPKLKEISPEAVDLMKHLLC-NSKRRFT-----IEDCMKHPFF
|.      ||.  ..||||.|| . |.| . ..|       ...  .||||
TWDWPMTHFPPEANLSPEAWDLIRRLCCPDPDHRLGSHGKGVDEIKSHPFF
Kinase 94173.m00229.AA S_TKc 83-365 29 2e-91 310.95 SMART 1-231 (231) Show / Hide 
Range on Protein: 83-365
Range on HMM: 1-231/231
Sequence Identity: 29% (89 aa)

FEKIKIIGKGEYGDVYLVRDKTDNKIYAMKIIQKSELIAKGQLRNTLTEKDLLSRMDSKWSVQLIYAFQDMYSIYFVMEYLPG--GDLLTVLMCRSY---
.|....|||| .| ||..|.| ...|.|.|||           .... | ..|.. . .. |.|...|||  ..|.||||..|  |||....  | .   
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

---LTLEETRFYIAEILLAIREVHSLGYIHCDIKPDNILLTKDGHIRLSDYGLSTPLHRDENFVTILDEVEDVCRDPNSERKEQPLKSNHKKDAICSTVG
   ..  ..|||...|..|.   ||.| ||.|.||.||||..  || ..| ||.. |                                       . .|
RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL--------------------------------------TTFCG

TPDYIAPEVLLKKPYGP-EVDLWSLGAIMYEMLYGQPPYLADTAINIIHWKSTLIFPKLKEISPEAVDLMKHLLC-NSKRRFTIEDCMK-------HPFF
||.|.|||||   .||. ..| ||.| |.||||.|.||.   .   ...             |||| |.....|. . ..| |. ....       ||.|
TPWYMAPEVL---GYGKCKCDWWSCGCILYEMLCGYPPFP--QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 94173.m00229.AA MAST 83-365 32 1.1e-80 259.77 In-house 1-334 (334) Show / Hide 
Range on Protein: 83-365
Range on HMM: 1-334/334
Sequence Identity: 32% (110 aa)

FEKIKIIGKGEYGDVYLVRDKTDNKIYAMKIIQKSELIAKGQLRNTLTEKDLLSRMDSKWSVQLIYAFQDMYSIYFVMEYLPGGDLLTVLMCRSYLTLEE
|| ||.|.|| || ||||. |. |...|||.| ||..| | .. .  .|.. |.  .. . | . |.||    ...||||. |||. . |    |.  . 
FEFIKPISKGAYGKVYLVKHKKTNDRFAMKVIKKSDMINKNMVDQVQVERNILAMYQNPFVVKMFYSFQTKNYLCMVMEYMEGGDCASLLHMYGYFDEWM

TRFYIAEILLAIREVHSLGYIHCDIKPDNILLTKDGHIRLSDYGLSTP-LHRDENFVTIL---------------DEVEDVCR-----------------
...||||. |..   || | .|.|.||||.|....||| | | |||   . .| | . ..               .   |  .                 
AKMYIAETVLCLEYLHSHGIVHRDLKPDNMLIDSNGHIKLTDFGLSKVGFMDDLNMMYEGYTPPNIFNNSTDPMNKNQQDYSQFPGDFGINGNTNKNQIQ

----DPNSERKEQPLKSNHKKDAICSTVGTPDYIAPEVLLKKP-YGPEVDLWSLGAIMYEMLYGQPPYLADTAI----NIIHWK-STLIFPKL------K
     |  ......    |... .|   ||||||||||.|... .|. || ||.| |||| | | ||   ||      ||.. .     .|        .
QQQEQPQCQQQNMRPHNIHQNKQCC---GTPDYIAPEVILGQGTHGKPVDWWSMGIIMYEFLVGCPPFNDDTPEEIFQNILNRNCNEIEWPEGGDINDDE

EISPEAVDLMKHLL-CNSKRRFTIE----DCMKHPFF
..|||| ||.. || .. . | .      . ..||||
AMSPEAQDLIEKLLQPDPRKRLGANNGADEVKQHPFF
Kinase 94173.m00229.AA DMPK 83-226 47 3.1e-80 197.7 In-house 1-145 (270) Show / Hide 
Range on Protein: 83-226
Range on HMM: 1-145/270
Sequence Identity: 47% (70 aa)

FEKIKIIGKGEYGDVYLVRDKTDNKIYAMKIIQKSELIAKGQLRNTLTEKDLLSRMDSKWSVQLIYAFQDMYSIYFVMEYLPGGDLLTVLMCRSY--LTL
|| .|.||.|  | | .|| |. |..||||.. | |.... .      |.| ... .|.| .|| |||||    |.|||| ||||||| || |    .  
FEILKVIGRGHFGEVQVVRHKQTNDVYAMKMMNKWEMLKRAETACFWEERDIMVHGNSRWITQLHYAFQDENYLYMVMEYMPGGDLLT-LMSRYEDRIPE

EETRFYIAEILLAIREVHSLGYIHCDIKPDNILLTKDGHIRLSDYG
. .|||.||. |||  .|..||.| ||||||.|| . |||.| | |
DMARFYLAEMVLAIHSIHQMGYVHRDIKPDNMLLDRHGHIKLADFG
Kinase 94173.m00229.AA Ciliate-E2 83-365 25 8.8e-77 261.4 In-house 1-365 (365) Show / Hide 
Range on Protein: 83-365
Range on HMM: 1-365/365
Sequence Identity: 25% (99 aa)

FEKIKIIGKGEYGDVYLVRD-----------------------KTDNKIYAMKIIQKSELIAKGQLRNTL----------TEKDLLSRMDSKWSVQLIYA
...||.||.| .|.||....                       |...|||||||..|...... |  . .           || .|......  ......
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

FQ--DMYSIYFVMEYLPGGDLLT-------------------VLMCRSYLTLEETR-------FYIAEILLAIREVHSLG-YIHCDIKPDNILLTKDGHI
||  |  .||.||||. ||||.                    ..  ..|.. . ..       ||||.|.||... || .  || ||||.|||.     |
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----I

RLSDYGLSTPLHRDENFVTILDEVEDVCRDPNSERKEQPLKSN------------HKKDAICSTVGTPDYIAPEVLLKKP---------YGPEVDLWSLG
 ..| |||.          ..|. .. ... ....|. .  .|             . . . ...||| | |||.| .|.         |. ..|.||||
KIIDFGLSK----------KYDDDNQNRTH-KQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLG

AIMYEMLYGQPPYLADTAINIIHWKSTLIFP----------------KLKEISPEAVDLMKH-----LLCNSKRRFT-IEDCMKHPFF
 |.||||.|.||.       ... .  . ||                . |..|.|. ||.|      | .. . |.| .|....||.|
VILYEMLFGKPPF------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase 94173.m00229.AA RSK 86-365 30 1.4e-76 260.72 In-house 1-278 (278) Show / Hide 
Range on Protein: 86-365
Range on HMM: 1-278/278
Sequence Identity: 30% (93 aa)

IKIIGKGEYGDVYLVRDK---TDNKIYAMKIIQKSELIAKGQ-LRNTLTEKDLLSRMD-SKWSVQLIYAFQDMYSIYFVMEYLPGGDLLTVLMCRSY---
.|  |.| || |.|.| .     ..|||||...|......   .| |.|| . |.|   ..  |.| ||||.   .| .|||..||.|.| |  . .   
LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFGC

LTLEETRFYIAEILLAIREVHSLGYIHCDIKPDNILLTK---DGHIRLSDYGLSTPLHRDENFVTILDEVEDVCRDPNSERKEQPLKSNHKKDAICSTVG
.. .| .||.||| ||..  |..| || |.||.|||..    .|||.|.| |..  .                              .....    . ..
FSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDESNEGHIKLTDFGFCKQF------------------------------RCDHNQWTMTFCY

TPDYIAPEVLL---KKP-YGPEVDLWSLGAIMYEMLYGQPPYLA-------DTAINIIHWKSTLIFPKLKEISPEAVDLMKHLLC-NSKRRFT-----IE
| .|.|||.|    ..  ..  .|.||||..||||| |.||. .       ..  .| . | .| .|  ...|.|| || ...|. . ..| .     .|
TIEYMAPEMLKRANQQGGHDKACDWWSLGVLMYEMLTGCPPFQGPNDNNRKEIMKRIQKGKFSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAE

DCMKHPFF
.  .||.|
EIKQHPWF
Kinase 94173.m00229.AA AktR 83-365 32 1.8e-76 260.39 In-house 1-268 (268) Show / Hide 
Range on Protein: 83-365
Range on HMM: 1-268/268
Sequence Identity: 32% (97 aa)

FEKIKIIGKGEYGDVYLVRDK-TDNKIYAMKIIQKSELIAKGQLRNTLTEKDLLS-RMDSKWSVQLIYAFQDMYSIYFVMEYLPGGDLLTVLMCRSYLTL
|. .|..||| .|.||||..| ...|.||||.| |...| . | . |.||.. .   ..    |.| |.||. . ..|.||| |||.|...|  .  .. 
FHVYKCLGKGAFGKVYLVQKKRDNQKQYAMKMIKKKKIIERNQMHHTITERNIMEMCCNHPFIVKLHYCFQTKEKLFFIMEYCPGGELFQHLKKKKKFSE

EETRFYIAEILLAIREVHSL-GYIHCDIKPDNILLTKDGHIRLSDYGLSTPLHRDENFVTILDEVEDVCRDPNSERKEQPLK-SNHKKDAICSTVGTPDY
|..|||.|.||||.   |.    |  |.||.|||| .|||....|.|||                             |. .  . | . .|   ||| |
EQARFYFAQILLALEYLHQHMNIIYRDLKPENILLDEDGHVKITDFGLSK---------------------------LQFMMHYDEKAYSFC---GTPEY

IAPEVLLK-KPYGPEVDLWSLGAIMYEMLYGQPPYLA--DTAINIIHWKST-LIFPKLKEISPEAVDLMK-HLLCNSKR-RFT-----IEDCMKHPFF
.|||...| |...  ||.|..|.  |||..|.||  .  .. ...   ... . ||. ...|... || .  |||.  . | .     .|.  .||.|
MAPEMITKKKGHNKSVDWWAFGIFIYEMVTGCPPFYHKNQNQMFQKIKIKQQNKFPYPSYFSSQCKDLIQRKLLCKNPNKRLGYYCNGWEEIKSHPWF
Kinase 94173.m00229.AA Akt 83-228 43 4.4e-62 197.23 In-house 1-148 (264) Show / Hide 
Range on Protein: 83-228
Range on HMM: 1-148/264
Sequence Identity: 43% (64 aa)

FEKIKIIGKGEYGDVYLVRDKTDNKIY-AMKIIQKSELIAKGQLRNTLTEKDLLSRMDSKWSVQLIYAFQDMYSIYFVMEYLPGGDLLTVLMCRSYLTLE
|. .|..||| .| |.||..| ..|.| |||...|. .|.|.|...|.||. .| ....   |.| |.||.   .||||.| .||.| . |  . . . .
FDFLKVLGKGSFGKVFLVKKKDTQKWYYAMKVLKKDYIIQKNQVEHTKTERNILQHCNHPFIVNLHYSFQTQDKLYFVMDYCNGGELFYHLQRKRRFSED

ETRFYIAEILLAIREVHSLGYIHCD-IKPDNILLTKDGHIRLSDYGLS
..|||.||| |||   || . | .|  || |||. |||||.| | ||.
RARFYCAEIILAIEHLHSKNIIYRDYLKPENILMDKDGHICLTDFGLC
Kinase 94173.m00229.AA MAST 83-228 39 1.1e-54 165.2 In-house 1-149 (337) Show / Hide 
Range on Protein: 83-228
Range on HMM: 1-149/337
Sequence Identity: 39% (59 aa)

FEKIKIIGKGEYGDVYLVRDKTDNKIYAMKIIQKSELIAKGQLRNTLTEKDLLSRMDSKWSVQLIYAFQD--MYSIYFVMEYLPGGDLLTVLMCRS-YLT
|| ||.|.|| || ||||. |. |...|||.| .. .| | |. .   |.. |.  .  . | . |.||       ..||||. |||  . |      . 
FEFIKCISKGAYGAVYLVKHKKTNDRFAMKVINCQDTIDKNQVDQVFVERNILTMYQNPFVVKMFYSFQTPCKKYLCMVMEYMEGGDCASLLRMYGNCMP

LEETRFYIAEILLAIREVHSLGYIHCDIKPDNILLTKDGHIRLSDYGLS
 .....||||. |..   || | .|.|.||||.|....||| | | |||
EWMAKMYIAETVLCLEYLHSYGIVHRDLKPDNMLIDSNGHIKLTDFGLS
Kinase 94173.m00229.AA GEK 83-226 46 1.2e-52 174.88 In-house 1-145 (269) Show / Hide 
Range on Protein: 83-226
Range on HMM: 1-145/269
Sequence Identity: 46% (68 aa)

FEKIKIIGKGEYGDVYLVRDKTDNKIYAMKIIQKSELIAKGQLRNTLTEKDLLSRMDSKWSVQLIYAFQDMYSIYFVMEYLPGGDLLTVL-MCRSYLTLE
|| .|.||.| .|.|  |. |  ...|||||..| |.. ..       |.| | . |..|  .| |||||   .|.||.|  ||||||.|      |  .
FEILKVIGRGAFGEVAVVKMKNTDQVYAMKILNKWEMLKRAETACFREERDVLVNGDRRWITNLHYAFQDENYLYLVMDYYVGGDLLTLLSKFEDRLPED

ETRFYIAEILLAIREVHSLGYIHCDIKPDNILLTKDGHIRLSDYG
  ||||||...||  || |.|.| ||||||.|| . ||||| |.|
MARFYIAEMVMAIDSVHQLHYVHRDIKPDNVLLDMNGHIRLADFG
Kinase 94173.m00229.AA DMPK 273-365 45 1.5e-48 117.56 In-house 162-270 (270) Show / Hide 
Range on Protein: 273-365
Range on HMM: 162-270/270
Sequence Identity: 45% (50 aa)

VGTPDYIAPEVL------LKKPYGPEVDLWSLGAIMYEMLYGQPPYLADTAI----NIIHW-KSTLIFPKLKE--ISPEAVDLMKHLLCNSKRRFT---I
|||||||.||||      .|  ||||.| ||.| .|||||||. |  ||.      .| .  |  | ||.  .  .|.|| || . |||....|.    .
VGTPDYISPEVLQAMEDDGKGRYGPECDWWSVGVCMYEMLYGETPFYADSLVETYGKIMNHCKNHLSFPDDPKWDVSEEAKDLICQLLCDREERLGRNGY

EDCMKHPFF
|| ..||||
EDFKCHPFF
Kinase 94173.m00229.AA Pkinase 83-228 32 3.5e-35 125.49 Pfam 1-159 (293) Show / Hide 
Range on Protein: 83-228
Range on HMM: 1-159/293
Sequence Identity: 32% (52 aa)

FEKIKIIGKGEYGDVYLVRDKTDNKIYAMKIIQKSELIAKGQLRNTL-TEKDLLSRMDSKWSVQLIYAFQDMYSIYFVMEYLPGG----DLLTVLM--CR
......||.| .| ||. ..| ..||.|.||| |..   . . .... .|  .. |....  |.|...|.|  .||.||||..||    || ....   .
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

SYL--TLEETRFYIAEILLAIREVHSLGYIHCDIKPDNILLTKDGHI----RLSDYGLS
  .  . .| .||. .|| ..   || | ||.|.||.|||. ..|||    ...| ||.
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLA
Kinase 94173.m00229.AA MAST 273-365 43 2.7e-29 86.15 In-house 229-337 (337) Show / Hide 
Range on Protein: 273-365
Range on HMM: 229-337/337
Sequence Identity: 43% (47 aa)

VGTPDYIAPEVLLKKP-YGPEVDLWSLGAIMYEMLYGQPPYLADTAIN-----IIHWKSTLIFPKL------KEISPEAVDLMKHLL-CNSKRRFTIE--
.||||||||||.|... ||. || ||.| |||| | | ||  .||        ||. .  . .|.        ..|||| ||.| ||  | | |      
CGTPDYIAPEVILGQGTYGKPVDWWSMGIIMYEFLVGCPPFNGDTPEEMIFQNIINHDREIEWPEEGDPNDDDCMSPEAQDLIKKLLQPNPKKRLGANGA

-DCMKHPFF
 . ..||||
DEIKQHPFF
Kinase 94173.m00229.AA GEK 273-365 44 1.8e-27 88.97 In-house 162-269 (269) Show / Hide 
Range on Protein: 273-365
Range on HMM: 162-269/269
Sequence Identity: 44% (48 aa)

VGTPDYIAPEVLL-----KKPYGPEVDLWSLGAIMYEMLYGQPPYLADTAIN----IIHWKSTLIFPKLKE---ISPEAVDLMKHLLCNSKRRF---TIE
|||||||.||.|      |  |||| | |||| .|||||||. |. |.  ..    |...|  . ||. ..   .| || ||...|.| . .|.    |.
VGTPDYISPEILQAMEDGKGRYGPECDWWSLGVCMYEMLYGETPFYAESLVETYGKIMNHKDHFQFPSQETDWDVSEEAKDLIRQLICSQEHRLGRNGIQ

DCMKHPFF
| .|||||
DFKKHPFF
Kinase 94173.m00229.AA Pkinase 273-365 32 1.6e-25 91.28 Pfam 172-293 (293) Show / Hide 
Range on Protein: 273-365
Range on HMM: 172-293/293
Sequence Identity: 32% (40 aa)

VGTPDYIAPEVLL-KKPYGPEVDLWSLGAIMYEMLYGQPPYLAD------TAINIIHWKST--LIFPKLKEIS-------------------PEAVDLMK
.|||.|.||||..  ..|||.|| ||.| |.|||| |.||.  .      . . .|  .    | |.  ...|                   .|. |..|
CGTPWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIK

HLLC-NSKRRFTIEDCMKHPFF
 .|| . |.| |.|....||.|
WCLCKDPKKRPTAEQILQHPWF
Kinase 94173.m00229.AA Akt 261-312 43 6.6e-21 63.5 In-house 149-203 (264) Show / Hide 
Range on Protein: 261-312
Range on HMM: 149-203/264
Sequence Identity: 43% (24 aa)

KSN-HKKDAICSTV-GTPDYIAPEVLLKKPYGPEVDLWS-LGAIMYEMLYGQPPY
| | .| . .. |. ||| |.|||.|... ..  || |. ||..||||..|.||.
KENIIKDHDKTKTFCGTPEYLAPEILNGNGHTKAVDWWGSLGCVMYEMMCGRPPF
Kinase 94173.m00229.AA TyrKc 83-365 19 1.1e-11 -34.02 SMART 1-280 (280) Show / Hide 
Range on Protein: 83-365
Range on HMM: 1-280/280
Sequence Identity: 19% (62 aa)

FEKIKIIGKGEYGDVYLVRDKTDNKIYAMKIIQKSELIAKGQLRNTLTEKDLLSRM--DSKWSVQLIYAFQDM-------YSIYFVMEYLPGGDLLTVL-
 ...|..| |..| ||. . |      | | ....       ..  . |  ....   . .  |.|. .  .          .. |||| |.|||.  | 
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR

MCRSYLTLEETRFYIAEILLAIREVHSLGYIHCDIKPDNILLTKDGHIRLSDYGLSTPLHRD-ENFVTILDEVEDVCRDPNSERKEQPLKSNHKKDAICS
 .|  |....   .   |    .  || ..|| |.   |.|........ || |||  .. | ..                             || . .
KHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQG--------------------------ESKDYYRK

TV--GTPD-----YIAPEVLLKKPYGPEVDLWSLGAIMYEML-YGQPPYLA-----DTAINIIHWKSTLIFPKLKEI---------SPEAVDLMKHLLCN
.   |. .       |||.. .. . .. | || |  |.|.. |||.||        ... .|..  .   ..  .          ..|  ..||     
KEHKGGKTMLPIRWMAPECINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHE

-SKRRFTIEDCMKHPFF
  . | | ...  | .|
DPEDRPTFSEI--HECF
Kinase 94173.m00229.AA S_TK_X 366-423 25 1.3e-09 39.22 SMART 1-79 (79) Show / Hide 
Range on Protein: 366-423
Range on HMM: 1-79/79
Sequence Identity: 25% (21 aa)

KEIDFDKIS----ESTAPIIPSVE----SETDTQNFD-EFEPRELLPEEESQDDVISLA--------------FTGFKFDR
..||.||.     | ..|..| .     |.||| ||| ||.  .    .  .|...| .              | || ...
RGIDWDKLYNQQKEIEPPFKPKIKEVYASPTDTSNFDPEFTEETPM--LTPDDPPLSNSMWQNEMETEIPPDPFRGFTYVF
Kinase 94173.m00229.AA Pkinase_Tyr 144-236 28 0.008085 10.17 Pfam 67-166 (270) Show / Hide 
Range on Protein: 144-236
Range on HMM: 67-166/270
Sequence Identity: 28% (28 aa)

VQLIYAFQ-DMYS--IYFVMEYLPGGDLLTVLMC----RSYLTLEETRFYIAEILLAIREVHSLGYIHCDIKPDNILLTKDGHIRLSDYGLSTPLHRDEN
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VRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDY
Kinase 94173.m00229.AA Pkinase_Tyr 83-99 35 0.045774 7.62 Pfam 1-17 (270) Show / Hide 
Range on Protein: 83-99
Range on HMM: 1-17/270
Sequence Identity: 35% (6 aa)

FEKIKIIGKGEYGDVYL
 ...| .|.|..|.||.
ITFGKKLGEGAFGEVYK
Kinase 94173.m00229.AA Akt 329-365 34 0.076493 1.58 In-house 222-264 (264) Show / Hide 
Range on Protein: 329-365
Range on HMM: 222-264/264
Sequence Identity: 34% (15 aa)

FPKLKEISPEAVDLMKHLLC-NSKRRF-----TIEDCMKHPFF
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FPDKDWISPECKDLISGLLNKDPKKRLGGGPNDAQEIKRHPWF
Kinase 94173.m00229.AA Pkinase_Tyr 280-312 34 2.459458 1.76 Pfam 182-216 (270) Show / Hide 
Range on Protein: 280-312
Range on HMM: 182-216/270
Sequence Identity: 34% (12 aa)

APEVLLKKPYGPEVDLWSLGAIMYEMLY-GQPP-Y
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APECINYGKFTTKSDVWSFGVLMWEIFTYGEQPTY