Gene 93440.m00427 (T.vaginalis)
93440.m00427
Species: T.vaginalis
Alias: 93440.m00427, TvagK0422
External Links:
Annotation:
Sequence
| Name | Sequence Type | Origin | Length | Description | Download |
|---|---|---|---|---|---|
| 93440.m00427.AA | Protein | None | 425 | None | Fasta, JSON |
| 93440.m00427.kin_dom | Protein Kinase Domain | None | 253 | None | Fasta, JSON |
Protein domains of 93440.m00427.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.
| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| PH | 93440.m00427.AA | PH | 2-99 | 16 | 8.6e-08 | 33.13 | SMART | 1-82 (82) | Show / Hide |
Range on Protein: 2-99 Range on HMM: 1-82/82 Sequence Identity: 16% (16 aa) SDLEGYLDVKRPSEKDWHIRFCTLSGNGLCMYEDETKIALSCQIIIDHDTNISCSDENEKALIFSITCPNAGVYAFRAKCLDSLVKWLNKLLQKLYPS .||.| .| |. |...| .. |. |.|. ... | ... ... . | |.. . .| |... ... .|.. . . .... VIKEGWLYKKS--K-RWKKRWFVLFNDCLYYYKDK---KPKGSIPLSDC-TVRE-P------CFEIHH-DR-TYYFQCESEEEMQEWMQAIQKAIHNN |
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| PH | 93440.m00427.AA | PH | 2-97 | 20 | 2.6e-07 | 29.02 | Pfam | 1-92 (92) | Show / Hide |
Range on Protein: 2-97 Range on HMM: 1-92/92 Sequence Identity: 20% (20 aa) SDLEGYLDVKRPSEKDWHIRFCTLSGNGLCMYEDETKIALSCQIIIDHDTNISCSDENEKALIFSITCPNAGVYAFRAKCLDSLVKWLNKLLQKLY .||.| .| . | |. |...| .| |..|.|.. . | ... .. ..|.. .| |.. . .| |.|. ... |.. . . .. VIKEGWLHKKG-KRKSWKKRWFVLFNNCLYYYKDDK-YRPKGSIPLSDC-QVTKVPDNKRPHCFQIRT-DRRTYYFQAESEEEMNDWMQAIQSACR |
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| Kinase | 93440.m00427.AA | AGC | 107-359 | 27 | 3e-140 | 365.09 | In-house | 1-395 (395) | Show / Hide |
Range on Protein: 107-359 Range on HMM: 1-395/395 Sequence Identity: 27% (111 aa) FEIISELGRGSYGKVMLAKYK------KTDELVAIKSIHKKF---LIDKHQVNTVLTE------------REILMKVD----------CPYIIK-LLFSF ||.. .|.||.|||.|.. | |... |.| . || ...|..| ..|| |.||.|.. .|.|.| | .|| FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF QSPSK--FYLVLEYSS---------GG-DLFSHLR---NSGRFTLDDIKIYIAE-------LAVAIHHLHK-NSIIYRD-LKPENVLFCADGHLKLTDFG |.... |.|.|| . || .||.||. ..|||. . ...|.|| .. |...||. . ||.|| |||||.|. .|||.|||||| QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG ISKILKQHS--------------------------------------------------DTTSTMCG--TKEYIAPEEILGNQYGYAVDWWQ--LGILLY .|.... |.|.|.|| | ||.||| . ||.|.||| ||.|.| LCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL----YGKACDWWSFGLGCLMY EIIARHTPFANENTQ----------TLFKNILSRN-VALFPIRDP---------------GAKSLIGHLLKKDPKERAC----------FKDIHASPFF | .. ..|| ..|.| .|..|.... . .... | ||.|| .||.|||..| ...| . |.| EMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNHPWF |
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| Kinase | 93440.m00427.AA | Akt | 107-359 | 43 | 1.5e-111 | 357.91 | In-house | 1-264 (264) | Show / Hide |
Range on Protein: 107-359 Range on HMM: 1-264/264 Sequence Identity: 43% (114 aa) FEIISELGRGSYGKVMLAKYKKTDELV-AIKSIHKKFLIDKHQVNTVLTEREILMKVDCPYIIKLLFSFQSPSKFYLVLEYSSGGDLFSHLRNSGRFTLD |... ||.||.|||.|.| |.|... |.|.. |. .|.| || ..||| || ....|.|..| .|||.. | |.|..| .||.||.||. .||. | FDFLKVLGKGSFGKVFLVKKKDTQKWYYAMKVLKKDYIIQKNQVEHTKTERNILQHCNHPFIVNLHYSFQTQDKLYFVMDYCNGGELFYHLQRKRRFSED DIKIYIAELAVAIHHLHKNSIIYRD-LKPENVLFCADGHLKLTDFGISK-ILKQHSDTTSTMCGTKEYIAPEEILGNQYGYAVDWWQ-LGILLYEIIARH .. |.||. || |||...||||| |||||.| .|||..||||| .| ..... |.| |.||| ||.||| ..|| .. ||||| ||...|| . RARFYCAEIILAIEHLHSKNIIYRDYLKPENILMDKDGHICLTDFGLCKENIIKDHDKTKTFCGTPEYLAPEILNGNGHTKAVDWWGSLGCVMYEMMCGR TPFANENTQTLFKNILSRNVALF--PIRDPGAKSLIGHLLKKDPKERAC-----FKDIHASPFF || |.. ...||.|.. .| . .| .|.|| ||.||||.| ..| . |.| PPFYNQDHHQMFKKIKNQPVKFPDKDWISPECKDLISGLLNKDPKKRLGGGPNDAQEIKRHPWF |
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| Kinase | 93440.m00427.AA | SGK | 107-359 | 36 | 3.1e-103 | 319.68 | In-house | 1-283 (283) | Show / Hide |
Range on Protein: 107-359 Range on HMM: 1-283/283 Sequence Identity: 36% (103 aa) FEIISELGRGSYGKVMLAKYKKT------------------DELVAIKSIHKKFLI-------DKHQVNTVLTER-EILMKVDCPYIIKLLFSFQSPSKF |.... .| ||.|||...| |.. | . |.| . |. | | ... ...|| || .. | |..| ..|| . | FDFLKVIGKGSFGKVYQVKHKDDETCQRVWLIFQSLLSQSEDKFYAMKVLQKQHIINEYRQDLKKKEQKHIMAERNVILKNMKHPFIVNLHYAFQTKWKL YLVLEYSSGGDLFSHLRNSGRFTLDDIKIYIAELAVAIHHLHKNSIIYRDLKPENVLFCADGHLKLTDFGISKILKQHSDTTSTMCGTKEYIAPEEILGN |.|..| ||..|.||. ..| | ..| ||.. |. .||. ||||||||||.| ..||..||||| .| ...|||.| ||| || ||| ... YFVMDYVNGGEMFYHLQREKHFPEDRARFYAAEIVCALEYLHSQDIIYRDLKPENILLDHQGHCCLTDFGLCKEGIKTNDTTFTFCGTPEYLAPEVLRKQ QYGYAVDWWQLGILLYEIIARHTPFANENTQTLFKNILSRNVALFPIRDPGAKSLIGHLLKKDPKERACFK----DIHASPFF .. .|||| ||..||| . || . |.|... ||.. . | . . |..|| ||.||||.| | .| ||| PHDRTVDWWCLGCVLYEMMYGLPPFYSRNKQQMYDNIINQPLQIPPQMSNDAWDLIQGLLQKDPKKRLGTKRDFMEIKNHPFF |
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| Kinase | 93440.m00427.AA | S_TKc | 107-359 | 33 | 9.8e-98 | 331.91 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 107-359 Range on HMM: 1-231/231 Sequence Identity: 33% (90 aa) FEIISELGRGSYGKVMLAKYKKTDELVAIKSIHKKFLIDKHQVNTVLTEREILMKVDCPYIIKLLFSFQSPSKFYLVLEYSSG--GDLFSHLRNSGR--- .||. ..|.|..|||.... |||...|||| |. .... |..||.| ..|.|.||. .||. ...|.|.|| .| ||||..... || YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL ---FTLDDIKIYIAELAVAIHHLHKNSIIYRDLKPENVLFCADGHLKLTDFGISKILKQHSDTTSTMCGTKEYIAPEEILGNQYGY-AVDWWQLGILLYE |. ... |..... |. ..|.. ||.|||||||.|.. |.|..|||....| .|.||| .|.||| . .||. ..||| .|..||| RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYE IIARHTPFANENTQTLFKNILSRNVALFPIRDPGAKSLIGHLLKKDPKERACFKDIHA-------SPFF ... .|| . |..||.|. .| ||..| ..|.|||..| .. . |.| MLCGYPPFP--QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF |
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| Kinase | 93440.m00427.AA | AktR | 107-359 | 35 | 1.6e-93 | 317.0 | In-house | 1-268 (268) | Show / Hide |
Range on Protein: 107-359 Range on HMM: 1-268/268 Sequence Identity: 35% (95 aa) FEIISELGRGSYGKVMLAKYK-KTDELVAIKSIHKKFLIDKHQVNTVLTEREILM-KVDCPYIIKLLFSFQSPSKFYLVLEYSSGGDLFSHLRNSGRFTL |... ||.| .|||.|.. | ......|.|.|.||..|.. | ..||| |. ... | |.|| ..||. .| ....||. ||.||.||.....|. FHVYKCLGKGAFGKVYLVQKKRDNQKQYAMKMIKKKKIIERNQMHHTITERNIMEMCCNHPFIVKLHYCFQTKEKLFFIMEYCPGGELFQHLKKKKKFSE DDIKIYIAELAVAIHHLHKN-SIIYRDLKPENVLFCADGHLKLTDFGISK--ILKQHSDTTSTMCGTKEYIAPEEILG-NQYGYAVDWWQLGILLYEIIA .....|.|. |. .||.. |||||||||| | |||.|.|||| || . . .... . ||| ||.||| |. ....||||..||..||... EQARFYFAQILLALEYLHQHMNIIYRDLKPENILLDEDGHVKITDFGLSKLQFMMHYDEKAYSFCGTPEYMAPEMITKKKGHNKSVDWWAFGIFIYEMVT RHTPFANENTQTLFKNILSRNVALFPIRD----PGAKSLIG-HLLKKDPKERAC-----FKDIHASPFF ..|| ..|....|..|.. . ... . .|.|| ||.|.|..| ...| |.| GCPPFYHKNQNQMFQKIKIKQ-QNKFPYPSYFSSQCKDLIQRKLLCKNPNKRLGYYCNGWEEIKSHPWF |
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| Kinase | 93440.m00427.AA | PKA | 107-359 | 39 | 1.1e-88 | 300.88 | In-house | 1-263 (263) | Show / Hide |
Range on Protein: 107-359 Range on HMM: 1-263/263 Sequence Identity: 39% (105 aa) FEIISELGRGSYGKVMLAKYKKTDELVAIKSIHKKFLIDKHQVNTVLTEREILMKVDCPYII-KLLFSFQSPSKFYLVLEYSSGGDLFSHLRNSGRFTLD |||| ||.||.|.|||.. |.. . .|.| . | .. || |..|. ||. .. |.|. |. ..|| ... |.|.|| .||..||.||.||||. . FEIIQTLGTGSFGRVMLCRHKHSGNYYAMKMLKKQEIVRLKQVEHVHNEKNILQNIKHPFIVKKMYWTFQDDRYLYMVMEYVPGGEMFSYLRKSGRFSNP DIKIYIA-ELAVAIHHLHKNSIIYRDLKPENVLFCADGHLKLTDFGISKILKQHSDTTSTMCGTKEYIAPEEILGN-QYGYAVDWWQLGILLYEIIARHT . |.|.| . |. ||. |||||||||| | .||.|.|||| .| .. |.|.||| ||.||| |.. .| .|||| |||| || | .. HAKFYAASQIVLALEYLHSQNIIYRDLKPENILIDKNGHIKITDFGFAKKVDD---RTWTLCGTPEYLAPEIIQSKNGHGKSVDWWALGILIYEMLAGYP PFANE--NTQTLFKNILSRNVALFPIRDPGA---KSLIGHLLKKDPKERA-CFK----DIHASPFF || .. .. ... |.. . . |. | |.|| .|| .|...| ..| || ..| PFYDHNRDPMQIYEKICNGKIKFPRHFDSDANYFKDLIKKLLQVDLTKRYGNMKNGVNDIKNHKWF |
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| Kinase | 93440.m00427.AA | MAST | 107-359 | 32 | 5.1e-87 | 280.54 | In-house | 1-334 (334) | Show / Hide |
Range on Protein: 107-359
Range on HMM: 1-334/334
Sequence Identity: 32% (107 aa)
FEIISELGRGSYGKVMLAKYKKTDELVAIKSIHKKFLIDKHQVNTVLTEREILMKVDCPYIIKLLFSFQSPSKFYLVLEYSSGGDLFSHLRNSGRFTLDD
||.| ...| |||| |.| ||| ...|.| | | .|.|..|..| .|| || ...|.. |. |||. .. ..|.|| .|||..|.|.. |.| .
FEFIKPISKGAYGKVYLVKHKKTNDRFAMKVIKKSDMINKNMVDQVQVERNILAMYQNPFVVKMFYSFQTKNYLCMVMEYMEGGDCASLLHMYGYFDEWM
IKIYIAELAVAIHHLHKNSIIYRDLKPENVLFCADGHLKLTDFGISKI-----------L---------------KQHSDTTSTM---------------
|.||||.. .. ||. .|. |||||.|.|. ..|| |||||| ||. . | |....
AKMYIAETVLCLEYLHSHGIVHRDLKPDNMLIDSNGHIKLTDFGLSKVGFMDDLNMMYEGYTPPNIFNNSTDPMNKNQQDYSQFPGDFGINGNTNKNQIQ
------------------------CGTKEYIAPEEILGNQ-YGYAVDWWQLGILLYEIIARHTPFANENTQTLFKNILSRN---VALFPI--------RD
||| .||||| ||| .| .|||| .|| .||... .|| .... .| |||.|| . . .
QQQEQPQCQQQNMRPHNIHQNKQCCGTPDYIAPEVILGQGTHGKPVDWWSMGIIMYEFLVGCPPFNDDTPEEIFQNILNRNCNEIEWPEGGDINDDEAMS
PGAKSLIGHLLKKDPKERACFK----DIHASPFF
| |. || || ||..| .. .. |||
PEAQDLIEKLLQPDPRKRLGANNGADEVKQHPFF
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| Kinase | 93440.m00427.AA | RSK | 110-359 | 34 | 1.6e-86 | 293.78 | In-house | 1-278 (278) | Show / Hide |
Range on Protein: 110-359 Range on HMM: 1-278/278 Sequence Identity: 34% (95 aa) ISELGRGSYGKVMLAKYK---KTDELVAIKSIHKKFLIDKHQ-VNTVLTEREILMKVD-CPYIIKLLFSFQSPSKFYLVLEYSSGGDLFSHLRNSGR--- ...||.|.|||| | . . .|. . | | ..|. .. . . ...|||.||. . .| |..| .|| ..|.||..|| .||.|| ||.. .. LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFGC FTLDDIKIYIAELAVAIHHLHKNSIIYRDLKPENVLFCA---DGHLKLTDFGISKILKQH-SDTTSTMCGTKEYIAPEEIL---GNQ-YGYAVDWWQLGI |. |. ..|.||...|. |||. ||.|||||||.|. .||.|||||| .|... . . | | |.| ||.||| . .. .. |.||| ||. FSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDESNEGHIKLTDFGFCKQFRCDHNQWTMTFCYTIEYMAPEMLKRANQQGGHDKACDWWSLGV LLYEIIARHTPFAN---ENTQTLFKNILSRN--VALF--PIRDPGAKSLIGHLLKKDPKERAC-----FKDIHASPFF |.|| . ..||.. .| . ..|.|.. . . . . . ||.|| ..|..||. | ..| ..|.| LMYEMLTGCPPFQGPNDNNRKEIMKRIQKGKFSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF |
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| Kinase | 93440.m00427.AA | PKC | 107-359 | 39 | 1.3e-83 | 270.85 | In-house | 1-262 (262) | Show / Hide |
Range on Protein: 107-359 Range on HMM: 1-262/262 Sequence Identity: 39% (104 aa) FEIISELGRGSYGKVMLAKYKKTDELVAIKSIHKKFLIDKHQVNTVLTEREILMKVD-CPYIIKLLFSFQSPSKFYLVLEYSSGGDLFSHLRNSGRFTLD |. . ||.||.||||||. |.|||. ||| . | |. . | ..||. .| .|. .| .||.... . |.|| |||| | ...|| . FNFLKVLGKGSFGKVMLAERKGTDEYYAIKVLKKDVIIQDDDVECTMTEKRVLALAWKHPFLTHLHCCFQTMDRLFFVMEYVNGGDLMFHIQQQRRFKEE DIKIYIAELAVAIHHLHKNSIIYRDLKPENVLFCADGHLKLTDFGISKILKQHSDTTSTMCGTKEYIAPEEILGNQYGYAVDWWQLGILLYEIIARHTPF . | || ..| . ||.. ||||||| .||| ..|| |..||| .| ||||| ||| .||||| . . .|| .|||| .|.|.|| | . || HARFYAAEIICALQFLHEKGIIYRDLKLDNVLLDHEGHIKIADFGMCKENMWNGDTTSTFCGTPDYIAPEILQYQEYGKSVDWWAFGVLMYEMMAGQSPF ANENTQTLFKNILSRNVALFPIR-DPGAKSLIGHLLKKDPKERA-C-------FKDIHASPFF |. .||..|. .|. ..|. |.|.. ...|.|..| | ..|| . ||| HGEDEDELFQSIMHDNP-HYPRWLSKEAVSICKGFMTKNPEKRLGCHPQQEEGEQDIREHPFF |
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| Kinase | 93440.m00427.AA | Pkinase | 107-359 | 28 | 6.1e-83 | 286.66 | Pfam | 1-293 (293) | Show / Hide |
Range on Protein: 107-359 Range on HMM: 1-293/293 Sequence Identity: 28% (83 aa) FEIISELGRGSYGKVMLAKYKKTDELVAIKSIHKKFLIDKHQVNTVL-TEREILMKVDCPYIIKLLFSFQSPSKFYLVLEYSSGG----DLFSHLR--NS ..|.. .|.||.|.| ... |.| ..||.| | |. .. ... .. .| .|. ....|.|..|. .|..... |.|.|| || |||.... .. YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH GRF--TLDDIKIYIAELAVAIHHLHKNSIIYRDLKPENVLFCADGHL----KLTDFGISKIL-KQHSDTTSTMCGTKEYIAPEEIL-GNQYGYAVDWWQL |.| . ...| |. ... .. ..|...||.|||||||.|. .||. |..|||..| . .. ..| ||| .|.||| |. |. ||..||.| . GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSC GILLYEIIARHTPFANE------NTQTLFKNILSRNVALFPIRD---------------------PGAKSLIGHLLKKDPKERACFKDIHASPFF |..||| . ...|| .. . . ....|... . . . .|..| .|.||||.| ...| .|.| GCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF |
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| Kinase | 93440.m00427.AA | Ciliate-E2-Unclassified | 107-359 | 26 | 6.5e-78 | 265.16 | In-house | 1-352 (352) | Show / Hide |
Range on Protein: 107-359
Range on HMM: 1-352/352
Sequence Identity: 26% (92 aa)
FEIISELGRGSYGKVMLAKYKKTDELVAIKSIHKKFLIDKHQVNTV---------LTERE-------------ILMKVDCPYIIKLLFSFQSPSKFYLVL
..|| .|.|..||| ... ||.... |.| ..|. ....|.... . ... || ..|.|.|... ||. ..|.|.
YKIIKQIGQGGFGKVYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKDEIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIVM
EYSSGGDLFSHLRNS-----------------GRFTLDDIK-----IYIAELAVAIHHLHKNS-IIYRDLKPENVLFCADG---HLKLTDFGISKILKQH
|| ||||. ..... .|| .| |.|.. ... .||.. ||.||.||||.|| .| ..|..|||||| ..|
EYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQN
---------------SDTTSTMCGTKEYI----APEEILGNQYG----YAVDWWQLGILLYEIIARHTPFANENTQT----------------LFKNILS
.. ..|.||| .|. ||| . |..|. |..|.| ||..|||.. || .| |..||.
NNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNIKQ
RNVALFP--------IRDPGAKSLIG----HLLKKDPKERACFKDIHASPFF
.|. .. . .| || .| .|||.|..| |..| |.|
KNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
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| Kinase | 93440.m00427.AA | MAST | 107-254 | 43 | 9.1e-64 | 193.43 | In-house | 1-151 (337) | Show / Hide |
Range on Protein: 107-254 Range on HMM: 1-151/337 Sequence Identity: 43% (65 aa) FEIISELGRGSYGKVMLAKYKKTDELVAIKSIHKKFLIDKHQVNTVLTEREILMKVDCPYIIKLLFSFQS--PSKFYLVLEYSSGGDLFSHLRNSG-RFT ||.| ...| ||.| |.| ||| ...|.|.| . .|||.||..| || || ...|.. |. |||. . ..|.|| .||| .|.||. | .. FEFIKCISKGAYGAVYLVKHKKTNDRFAMKVINCQDTIDKNQVDQVFVERNILTMYQNPFVVKMFYSFQTPCKKYLCMVMEYMEGGDCASLLRMYGNCMP LDDIKIYIAELAVAIHHLHKNSIIYRDLKPENVLFCADGHLKLTDFGISKI . |.||||. .. ||. .|. |||||.|.|. ..||.|||||| ||. EWMAKMYIAETVLCLEYLHSYGIVHRDLKPDNMLIDSNGHIKLTDFGLSKV |
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| Kinase | 93440.m00427.AA | MAST | 266-359 | 36 | 3.4e-26 | 76.47 | In-house | 229-337 (337) | Show / Hide |
Range on Protein: 266-359 Range on HMM: 229-337/337 Sequence Identity: 36% (40 aa) CGTKEYIAPEEILGNQ-YGYAVDWWQLGILLYEIIARHTPFANENTQT-LFKNILS--RNVALFPI--------RDPGAKSLIGHLLKKDPKERACFK-- ||| .||||| ||| || .|||| .|| .||... .|| .. . .| ||.. |.. .. | |. || || ..||.| .. CGTPDYIAPEVILGQGTYGKPVDWWSMGIIMYEFLVGCPPFNGDTPEEMIFQNIINHDREIEWPEEGDPNDDDCMSPEAQDLIKKLLQPNPKKRLGANGA -DIHASPFF .| ||| DEIKQHPFF |
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| Kinase | 93440.m00427.AA | Pkinase_Tyr | 107-269 | 24 | 3.3e-18 | 62.31 | Pfam | 1-175 (270) | Show / Hide |
Range on Protein: 107-269 Range on HMM: 1-175/270 Sequence Identity: 24% (44 aa) FEIISELGRGSYGKVMLAKYK----KTDELVAIKSIHKKFLIDKHQ--VNTVLTEREILMKV-DCPYIIKLL-FSF-QSPS-KFYLVLEYSSGGDLFSHL ... .||.|..|.|.....| .|. ||.|.. | ...| . | .|... ..| |..|. |. . . |.|.|| .||| ..| ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KE-GAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYL RN----SGRFTLDDIKIYIAELAVAIHHLHKNSIIYRDLKPENVLFCADGHLKLTDFGISKILKQHSDTT-STMCGTK |. ...|. |. . .. | . .|. . .| ||| |.| ... | .||| .. . .. |. . |.| RKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDI-YNDDYYYRKRGGGK |
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| Kinase | 93440.m00427.AA | TyrKc | 107-359 | 20 | 5.9e-17 | 51.38 | SMART | 1-280 (280) | Show / Hide |
Range on Protein: 107-359 Range on HMM: 1-280/280 Sequence Identity: 20% (59 aa) FEIISELGRGSYGKVMLAKYKKTDELVAIKSIHKKFLIDKHQVNTVLTEREILMKV--DCPYIIKLLFSFQSP-------SKFYLVLEYSSGGDLFSHLR . . .||.| .|.|.....| . ||.|.... . . | .|..|. . | |..|. .. ..|.|| ..||| ..|| ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR NSGR-FTLDDIKIYIAELAVAIHHLHKNSIIYRDLKPENVLFCADGHLKLTDFGISKILKQH------SDTTSTMC--GTKE-----YIAPEEILGNQYG .... ....| . | .||.. .| ||| |.| .... | .||| |. .. . .|. ... |.| ||| | . . KHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFT YAVDWWQLGILLYEIIAR-HTPFAN-----ENTQTLFKNILSRNVALFPIR---------DPGAKSLIGHLLKKDPKERACFKDIHASPFF . | | |....|| . .| . . | ..... ... | . ... . ||..| .|..| .| TKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF |
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