Gene 81317.m00121 (T.vaginalis)

81317.m00121

Species: T.vaginalis
Alias: 81317.m00121, TvagK0009
External Links:
Annotation:

Classification

Group: Other
Family: Aur

Sequence

Name Sequence Type Origin Length Description Download
81317.m00121.AA Protein None 294 None Fasta, JSON
81317.m00121.kin_dom Protein Kinase Domain None 252 None Fasta, JSON

Protein domain

Protein domains of 81317.m00121.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 81317.m00121.AA Aur 39-290 58 1.6e-217 580.96 In-house 1-257 (257) Show / Hide 
Range on Protein: 39-290
Range on HMM: 1-257/257
Sequence Identity: 58% (150 aa)

FEIGRPLGTGKFGRVYLAREKKTHFIVAIKVMYKSHLAKAEIEHQVRREIEIQSHLRHPNILRLYGFFYDKAKIYLVMEYAPNGELFKILREN--DRFDE
||||.||| ||||.|||||.||||||.|.||| |. . | ..|||.||||.|||||.|||||..||.|.|. .|||..||||.|||.| |.     ||||
FEIGKPLGKGKFGNVYLARHKKTHFIFALKVMFKEQIKKYCMEHQLRREIKIQSHLNHPNILKMYGYFHDDQRIYLILEYAPGGELYKELQKQPNKRFDE

ETSAFYIMQIVEAIKYCHSKGVIHRDIKPENILIG-SDGNLKISDFGWSASISNTNRRSTLCGTLDYLPPEMLNGEKYDFAVDIWGIGVLLYEFLTGNAP
...|.|. || .|..|||||..|||||||||||.. ..||.||.|||||.   | |||.|.||||||.|||| .|. .|. |||| .|||.||...| .|
QRAAKYMYQICNALDYCHSKNIIHRDIKPENILLDQCNGNIKICDFGWSVHCPNNNRRMTFCGTLDYMPPEMVEGQMHDHKVDIWCLGVLCYELCHGCPP

FEE-PERDKTIERIK-SVNIKFPDDMPELAKDLIQKLLQKDPTKRISLGEVGSHPWI
||.  ..|.|..|||  |.|.||.  .. |||||.|.||.|| .|..| .. .||||
FESNENHDETYDRIKNKVDIQFPSHISKEAKDLISKILQHDPKQRMTLDQIMNHPWI
Kinase 81317.m00121.AA AGC 39-290 28 1.8e-133 347.2 In-house 1-395 (395) Show / Hide 
Range on Protein: 39-290
Range on HMM: 1-395/395
Sequence Identity: 28% (113 aa)

FEIGRPLGTGKFGRVYLAREK------KTHFIVAIKVMYKSH---------LAKAEIEHQ------VRREIEIQSHLR----------HPNILR-LYGFF
||. ...|.| ||.|||.|.|       |  . |.||. |.|         .... .||       |..| .| ....          ||.| . |.  |
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF

YDKAK--IYLVMEYAP---------NG-ELFKILR---ENDRFDEETSAFYIMQ-------IVEAIKYCHS-KGVIHRD-IKPENILIGSDGNLKISDFG
 || .  .|.||||.|          | ||| .|.    . |||||.. ||. .       || |. | || .|.|||| .||||||. .||..|..|||
QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG

WSASIS---------------------------------------------------NTNRRSTLCG--TLDYLPPEMLNGEKYDFAVDIWG--IGVLLY
 .  .                                                    ...| .|.||  | .|..||.|    |..|.|.|.   |.|.|
LCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL----YGKACDWWSFGLGCLMY

EFLTGNAPFEEPE----------RDKTIERIK------SVNIKFP----------DDMPELAKDLIQKLLQKDPTKRIS----------LGEVGSHPWI
|.|||  ||   .          .... ..|.      . ..|||          . . . |||||.|||.|||.||.             |. .||| 
EMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNHPWF
Kinase 81317.m00121.AA S_TKc 39-290 38 3.9e-113 383.06 SMART 1-231 (231) Show / Hide 
Range on Protein: 39-290
Range on HMM: 1-231/231
Sequence Identity: 38% (103 aa)

FEIGRPLGTGKFGRVYLAREKKTHFIVAIKVMYKSHLAKAEIEHQVRREIEIQSHLRHPNILRLYGFFYDKAKIYLVMEYAPN--GELFKILRENDR---
.||.|..| | ||.||..|.|||. |||||..            ..||||.| .. .|||| .||..|.|  ..|.||||...  |.||...... |   
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

---FDEETSAFYIMQIVEAIKYCHSKGVIHRDIKPENILIGSDGNLKISDFGWSASISNTNRRSTLCGTLDYLPPEMLNGEKYDF-AVDIWGIGVLLYEF
   |.| . .||. ||..|..||||.|.||||.||||||. .  ..||.||| .. .      .|.|||..|..||.|   .|.. ..|.| .|..|||.
RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEM

LTGNAPFEEPERDKTIERIKSVNIKFPDDMPELAKDLIQKLLQKDPTKRISLGEVGS-------HPWI
|.|  ||.  . ......|.          .. |||.|.|.|||||.||..  |.         |||.
LCGYPPFP--QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 81317.m00121.AA CAMKL 39-290 34 1.6e-106 340.94 In-house 1-297 (297) Show / Hide 
Range on Protein: 39-290
Range on HMM: 1-297/297
Sequence Identity: 34% (103 aa)

FEIGRPLGTGKFGRVYLARE-KKTHFIVAIKVMYKSHLAKAEIEHQ------------VRREIEIQSHLR---HPNILRLYGFFYDKAK------IYLVM
..||. ||.| || | ||.  . |   ||||.. |. . . .. ..            .||||.|...|.   |||| .||  .... .      |||||
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVM

EYAPNGE--LFKILREN----DRFDEETSAFYIMQIVEAIKYCHSKGVIHRDIKPENILIGSDG--NLKISDFGWSASISN-----TNRRSTLCGTLDYL
||...||  ||  ....    .|..|.   .|  |||.|..||||.|..||||||||||. ..|  |.||.||| |. . .      .  .| ||.. | 
EYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPYM

PPEMLNG--EKYD-FAVDIWGIGVLLYEFLTGNAPFEEP--------ERDKTIERIKSVNIKFP--DDMPELAKDLIQKLLQKDPTKRISLGEVGSHPWI
.||...|  ..|| ..|||| .||.||  ..|. ||...           .  ..|..   ..|   ...  ..|||.|.||..|.||... .. .||| 
APEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMNHPWM
Kinase 81317.m00121.AA CAMK 44-290 24 8.10000000001e-105 338.74 In-house 1-425 (425) Show / Hide 
Range on Protein: 44-290
Range on HMM: 1-425/425
Sequence Identity: 24% (105 aa)

PLGTGKFGRVYLAREKKTH------------FIVAIKVMYKSHLAK-------------------------AEIEHQVRREIEIQSH-------LRHPNI
 ||.| || |.|...|.|               ||||.. |. | .                         .. ...||||||| ..       |.||||
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

LRLYGFFYD-------------------KAKIYLVM---EYAPNGEL----FKILREN---------------DRFDEETSAFYIMQIVEAIKYCHSKGV
..|| .. |                   . ..|.||   ||...|||    |  ..|.                ||.|.  ..|. ||..|..||||...
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNI

IHRDIKPENILIGSD-----------------GNLKISDFGWSASISN------------------------TNRRSTLCGTLDYLP-PEMLNG------
.|||.||||||. ..                 .|.||.||| .. .                          .   .| |||. | . ||.|||      
VHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNM

--------EKYDFAVDIWGIGVLLYEFLTGNAPFEEP-------------ERDKTIERIKSVNIKFPDDMPEL------------------------AKD
        . |....|.| .||.||  |.|  ||...             .  .. |.|.. .  ||...                           .||
QNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECKD

LIQKLLQKDPTKRISLGEVGSHPWI
||.|.||.||.||... .. .|||.
LIRKMLQVDPEKRMTIEQCLNHPWM
Kinase 81317.m00121.AA Pkinase 39-290 36 9.5e-104 355.78 Pfam 1-293 (293) Show / Hide 
Range on Protein: 39-290
Range on HMM: 1-293/293
Sequence Identity: 36% (107 aa)

FEIGRPLGTGKFGRVYLAREKKTHFIVAIKVMYKSHLAKAEIEHQVR-REIEIQSHLRHPNILRLYGFFYDKAKIYLVMEYAPNG----ELFKILR--EN
..|||..| | ||.||....|.|  |||.|.. |.|  . . .. .| .||.|  .|.||||.|||..|.|| .||.||||...|    .|| ...  ..
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

DRF--DEETSAFYIMQIVEAIKYCHSKGVIHRDIKPENILIGSDGNL----KISDFGWSAS--ISNTNRRSTLCGTLDYLPPEMLN-GEKYDFAVDIWGI
 .|  .|..  ||. ||.....||||.|.||||.||||||| ..|..    ||.||| ..   . |    .|.|||..|..|| .. |..|. .||.|..
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSC

GVLLYEFLTGNAPFEEP------ERDKTIERIKSVNIKFPDD---------------------MPELAKDLIQKLLQKDPTKRISLGEVGSHPWI
|..|||.|.|. || .       . .. |.||..  ..|. .                     ..| .||.| ..|.|||.||..  ..  |||.
GCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase 81317.m00121.AA MARK 39-290 38 1.3e-95 312.96 In-house 1-262 (262) Show / Hide 
Range on Protein: 39-290
Range on HMM: 1-262/262
Sequence Identity: 38% (100 aa)

FEIGRPLGTGKFGRVYLAREKKTHFIVAIKVMYKSHLAKAEIEHQVRREIEIQSHLRHPNILRLYGFFY--DKAK-IYLVMEYAPNGELFKILREN--DR
..... .|.| .. |.||. |.|.  ||||.. |  | . .    |.||||| ..| |||| .|.  .   .. . |||.||||..|||.  ...    |
YKMLKTIGHGSYAKVKLACHKHTGRKVAIKIYEKFKLNDPQWMKNVMREIEIMKKLDHPNIIKLFHVIEQDTEQHQIYLIMEYASGGELYDYIKAHPNGR

FDEETSAFYIMQIVEAIKYCHSKGVIHRDIKPENILIGSDG--NLKISDFGWSASISNTNRRSTLCGTLDYLPPEMLNGEKYD-FAVDIWGIGVLLYEFL
  ||    .  |||.|..|||||...||||||||||| ..|  | ||.|||.|. | . .. .| |||. | .||......|| ..||||  ||.||  .
LHEEEARRIFRQIVSAVNYCHSKNIVHRDIKPENILIDENGNHNIKIIDFGFSICIPPGQKLNTFCGTPPYMAPEIFLKKPYDGPKVDIWSLGVVLYFMV

TGNAPFEEPE--RDKTIERIKSVNIKFPDDMPELAKDLIQKLLQKDPTKRISLGEVGSHPWI
.|. ||..      .  ..| . . ..|. ..  ...|||.||. .| .|... |. .|||.
CGYFPFDGDTQDYKELYKKILRGKYDIPCHVSKECRNLIQRLLTVNPEERPTIEEIMKHPWM
Kinase 81317.m00121.AA Ciliate-E2 39-290 29 3.9e-94 319.06 In-house 1-365 (365) Show / Hide 
Range on Protein: 39-290
Range on HMM: 1-365/365
Sequence Identity: 29% (111 aa)

FEIGRPLGTGKFGRVYLAREKKT-----------------------HFIVAIKVMYKSHLAKAEIEHQVRREIE----------IQSHLRHPNILRLYGF
... . .|.| || ||... .|.                        .|.|.|.| |. .   . | .. |||.          |...| ||||...| .
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

FY--DKAKIYLVMEYAPNGELFKILREND-----------RFDEETSA---------------FYIMQIVEAIKYCHSKG-VIHRDIKPENILIGSDGNL
|.  |. .|||||||.  |.||.....|.           .|.|.  .               ||| .|..|..|.|||. .|||||||||||.     .
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----I

KISDFGWSASISNTNRRST--------------------------------LCGTLDYLPPEMLNGEK---------YDFAVDIWGIGVLLYEFLTGNAP
||.||| |  ... | . |                                .|||. |..||.|||.|         ||...||| .||.|||.|.|. |
KIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPP

FEEPERDKTIERIKSVNIKFP------------------DDMPELAKDLIQK----LLQKDPTKRIS-LGEVGSHPWI
|        .. ||  .|.||                  .. .. .||||.|    .||||| |||.   ..  |||.
F--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase 81317.m00121.AA Ciliate-E2-Unclassified 39-290 26 1.4e-87 297.28 In-house 1-352 (352) Show / Hide 
Range on Protein: 39-290
Range on HMM: 1-352/352
Sequence Identity: 26% (95 aa)

FEIGRPLGTGKFGRVYLAREKKTHFIV-----AIKVMYKS-HLAKAEIEHQVRREIEIQSH----------------LRHPNILRLYGFFY--DKAKIYL
..|.. .|.| || ||....||.   .     ..|.. .. .. . ..   .. ..|....                | ||...... |..  || .||.
YKIIKQIGQGGFGKVYKCQHKKQK-QYYAMKYMKKIQIYKQKQIMNKD-EIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYI

VMEYAPNGELFKILRENDR-----------------FDEETSA-----FYIMQIVEAIKYCHSKG-VIHRDIKPENILIGSDG---NLKISDFGWSASIS
||||...|.|.......                   |.|. ..     ||. ||.....|.|.|. .|||||||||||. ..|   ..||.||| |  . 
VMEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQ

N----------------TNRRSTLCGTLDYL----PPEMLNGEKYD----FAVDIWGIGVLLYEFLTGNAPFEEPERDK----------------TIERI
.                 .. .| |||. |.    .||.| |..||    ...|||. ||.|||.|.|. ||. . ...                 .. |
QNNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNI

KSVNIKFP--------DDMPELAKDLIQ----KLLQKDPTKRISLGEVGSHPWI
|  ||.||        .. .. |||.|.    |.|.|.| |||.. ..  |||.
KQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase 81317.m00121.AA PLK 39-290 35 1e-83 272.51 In-house 1-258 (258) Show / Hide 
Range on Protein: 39-290
Range on HMM: 1-258/258
Sequence Identity: 35% (92 aa)

FEIGRPLGTGKFGRVYLAREKKTHFIVAIKVMYKSHLAKAEIEHQVRREIEIQSHLRHPNILRLYGFFYDKAKIYLVMEYAPNGELFKILREN-DRFDEE
.|.|..|| | | ..| ... .|. ..||||  || ..|      ...||||.. |.||||.... || |.  .|.|.||..|..|. ...    |. |.
YERGHFLGKGGFAKCYEMTDIHTKQVYAIKVVPKSLMQKPHQREKMKQEIEIHRQLHHPNIVKFHHFFEDHENVYIVLEYCHNRSLMHYHKRRAKRLTEP

TSAFYIMQIVEAIKYCHSKGVIHRDIKPENILIGSDGNLKISDFGWSASISNT-NRRSTLCGTLDYLPPEMLNGEK--YDFAVDIWGIGVLLYEFLTGNA
   .|..|||...|| |....||||.|. |... .. ..|| ||| .. . .   |. |.|||  |  || |.| |  ... ||.| .|. .| .|.|  
EVRYYMYQIVQGLKYLHQHRIIHRDLKLGNLFLNDNMHVKIGDFGLATRLEYDGERKKTMCGTPNYIAPEVLDGNKQGHSYEVDCWSLGCIMYTLLIGKP

PFEEPERDKTIERIKSVNIKFPDD--MPELAKDLIQKLLQKDPTKRISLGEVGSHPWI
|||  .   | .|||  .  ||..      |||||||.|...|..|... .. .||. 
PFETKDVKETYKRIKHNHYSFPEHCPISDEAKDLIQKMLNWNPDERPTIDQILQHPFF
Kinase 81317.m00121.AA RSK 42-290 34 4.9e-82 278.86 In-house 1-278 (278) Show / Hide 
Range on Protein: 42-290
Range on HMM: 1-278/278
Sequence Identity: 34% (97 aa)

GRPLGTGKFGRVYLAREK---KTHFIVAIKVMYKSHLAKAE--IEHQVRREIEIQSHLR-HPNILRLYGFFYDKAKIYLVMEYAPNGELFKILRENDR--
 . ||.| .| |.| |..   .|  | | ||  |. .....  ..| ...|..| .. . ||.| .|.  | .. |.||.||| . ||||. |..  .  
LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRH-TMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFG

-FDEETSAFYIMQIVEAIKYCHSKGVIHRDIKPENILIGS---DGNLKISDFGWSAS--ISNTNRRSTLCGTLDYLPPEMLN---GEK-YDFAVDIWGIG
 |.|.. .||. .|| |... |..|.||||.||||||  .   .| .|..||| .    ......  | |.|..|..||||.   ... .| |.|.|  |
CFSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDESNEGHIKLTDFGFCKQFRCDHNQWTMTFCYTIEYMAPEMLKRANQQGGHDKACDWWSLG

VLLYEFLTGNAPFEE---PERDKTIERIKSVN--IKFP--DDMPELAKDLIQKLLQKDPTKRIS-----LGEVGSHPWI
||.|| |||. ||       |.....||.. .   ..|  . . . |||||.|.|..|| ||..     . |. .|||.
VLMYEMLTGCPPFQGPNDNNRKEIMKRIQKGKFSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF
Kinase 81317.m00121.AA AktR 39-290 36 3.9e-81 275.85 In-house 1-268 (268) Show / Hide 
Range on Protein: 39-290
Range on HMM: 1-268/268
Sequence Identity: 36% (98 aa)

FEIGRPLGTGKFGRVYLAREK-KTHFIVAIKVMYKSHLAKAEIEHQVRREIEIQS-HLRHPNILRLYGFFYDKAKIYLVMEYAPNGELFKILRENDRFDE
|.. ..|| |.||.|||...| ..  ..|.|.  |... . . .|....|  |   . .|| | .|. .| .| |....||| |.|||| .|. . .|.|
FHVYKCLGKGAFGKVYLVQKKRDNQKQYAMKMIKKKKIIERNQMHHTITERNIMEMCCNHPFIVKLHYCFQTKEKLFFIMEYCPGGELFQHLKKKKKFSE

ETSAFYIMQIVEAIKYCHSK-GVIHRDIKPENILIGSDGNLKISDFGWSA---SISNTNRRSTLCGTLDYLPPEMLNG-EKYDFAVDIWGIGVLLYEFLT
|.. ||. ||. |. | |..  .| ||.||||||...||..||.||| |     .... .  ..|||  |..|||..  . ....||.| .|...|| .|
EQARFYFAQILLALEYLHQHMNIIYRDLKPENILLDEDGHVKITDFGLSKLQFMMHYDEKAYSFCGTPEYMAPEMITKKKGHNKSVDWWAFGIFIYEMVT

GNAPFEEPERDKTIERIKSVN-IKFPDDMPE--LAKDLIQ-KLLQKDPTKRIS-----LGEVGSHPWI
|. ||.   .   ...||. . .|||. ..    .||||| |||.|.|.||.        |. |||| 
GCPPFYHKNQNQMFQKIKIKQQNKFPYPSYFSSQCKDLIQRKLLCKNPNKRLGYYCNGWEEIKSHPWF
Kinase 81317.m00121.AA Pkinase_Tyr 39-182 33 2e-30 103.7 Pfam 1-156 (270) Show / Hide 
Range on Protein: 39-182
Range on HMM: 1-156/270
Sequence Identity: 33% (53 aa)

FEIGRPLGTGKFGRVYLAREK----KTHFIVAIKVMYKSHLAKAE-IEHQVRREIEIQSHL-RHPNILRLYGFFY-DKAK--IYLVMEYAPNGELFKILR
 ..|. || | ||.||... |    .|.  ||.|.. | .  . . .     ||..| ..| .||||.||||  . ..    ||.||||.|.| | . ||
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR

E----NDRFDEETSAFYIMQIVEAIKYCHSKGVIHRDIKPENILIGSDGNLKISDFG
.    ..... ..   . .|| ..  | .||. ||||.   |.|.....  ||.|||
KHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFG
Kinase 81317.m00121.AA TyrKc 39-290 26 6.2e-27 96.73 SMART 1-280 (280) Show / Hide 
Range on Protein: 39-290
Range on HMM: 1-280/280
Sequence Identity: 26% (77 aa)

FEIGRPLGTGKFGRVYLAREKKTHFIVAIKVMYKSHLAKAEIEHQVRREIEIQSHL--RHPNILRLYGFFYDK-------AKIYLVMEYAPNGELFKILR
 . |. || | ||.||... |     ||.|.. ...      .   .||..| ..|  .||||.||||   ..         ...||||.|.| | . ||
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR

ENDR-FDEETSAFYIMQIVEAIKYCHSKGVIHRDIKPENILIGSDGNLKISDFGWSASISNT---------NRRST--LC---GTLDYLPPEMLNGEKYD
.. . .  ..   .  || .   | |||..||||.   |.|.|...  |||||| |  | .           | ..   .     .  ..|| .|  |. 
KHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFT

FAVDIWGIGVLLYEFLT-GNAPFEE-----PERDKTIERIKSV-NIKFPDD--------MPELAKDLIQKLLQKDPTKRISLGEVGSHPWI
.. |.|  ||...| .| |  | ..      . .  ||..|.    . |..        .|.   .....  . || .| .  |.  |  .
TKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF
Kinase 81317.m00121.AA Pkinase_Tyr 203-250 29 0.104205 6.41 Pfam 181-231 (270) Show / Hide 
Range on Protein: 203-250
Range on HMM: 181-231/270
Sequence Identity: 29% (15 aa)

LPPEMLNGEKYDFAVDIWGIGVLLYEFLT-GNAP-FEEPERDKTIERI-KS
..|| .|  |.  . |.|  |||..| .| |  | ...      .|.| ..
MAPECINYGKFTTKSDVWSFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYED