Gene 81997.m00106 (T.vaginalis)

81997.m00106

Species: T.vaginalis
Alias: TvagK0369, 81997.m00106
External Links:
Annotation:

Classification

Group: Other
Family: Aur

Sequence

Name Sequence Type Origin Length Description Download
81997.m00106.AA Protein None 297 None Fasta, JSON
81997.m00106.kin_dom Protein Kinase Domain None 251 None Fasta, JSON

Protein domain

Protein domains of 81997.m00106.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 81997.m00106.AA Aur 38-288 59 7.89999999999e-216 576.4 In-house 1-257 (257) Show / Hide 
Range on Protein: 38-288
Range on HMM: 1-257/257
Sequence Identity: 59% (154 aa)

FEIGRPLGTGKFGRVYLAREAKSKFIVGIKVLNKAQLQKASIEHQLRREIEIQSHLRHPNIIRLYGYFYDATRICLIIEYAARGELFSILRDA--GRFDE
||||.||| ||||.|||||. |..||. .||..| |..|  .||||||||.|||||.||||...||||.|..|| ||.||| .|||.. |. .  .||||
FEIGKPLGKGKFGNVYLARHKKTHFIFALKVMFKEQIKKYCMEHQLRREIKIQSHLNHPNILKMYGYFHDDQRIYLILEYAPGGELYKELQKQPNKRFDE

HTAAEYIVQMCDAIDYCHSKHIIHRDIKPENILVG-LNGELKIADFGWSVHAP-TSRRTTLCGTLDYLPPEMIEGHDHDKSVDIWTLGVLLYEFLVGEPP
 .|| |. |.|.|.||||||.||||||||||||.. .||..||.|||||||.|  .||.|.||||||.||||.|| .||..|||| ||||.||...| ||
QRAAKYMYQICNALDYCHSKNIIHRDIKPENILLDQCNGNIKICDFGWSVHCPNNNRRMTFCGTLDYMPPEMVEGQMHDHKVDIWCLGVLCYELCHGCPP

FET-DSQRNTCRRII-NVDIRFPSFVTPLARDLILRLLQKDPAKRMPLNQVRSHPWI
||  ...  | .||. .|||.|||.... |.||| ..||.|| .||.|.|. .||||
FESNENHDETYDRIKNKVDIQFPSHISKEAKDLISKILQHDPKQRMTLDQIMNHPWI
Kinase 81997.m00106.AA AGC 38-288 24 9.5e-120 310.86 In-house 1-395 (395) Show / Hide 
Range on Protein: 38-288
Range on HMM: 1-395/395
Sequence Identity: 24% (99 aa)

FEIGRPLGTGKFGRVYLAREA------KSKFIVGIKVLNKAQ---------LQKASIEHQ------LRREIEIQSHLR----------HPNIIR-LYGYF
||. ...|.| ||.|||.|.        .. .  .|||.|.          .... .||       ...| .| ....          ||.|.. |.  |
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF

YDATR--ICLIIEYAA---------RG-ELFSILR---DAGRFDEHTAAEYIVQ-------MCDAIDYCHS-KHIIHRD-IKPENILVGLNGELKIADFG
 | ..  .... ||.           | |||..|.   . ||||| .|  |. .       .. |..| || ..||||| .||||||   .| .|..|||
QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG

WSVHAPTS----------------------------------------------------RRTTLCG--TLDYLPPEMIEGHDHDKSVDIWT--LGVLLY
 .   ...                                                    | .|.||  | .|..||..    ..|..|.|.  ||.|.|
LCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL----YGKACDWWSFGLGCLMY

EFLVGEPPFETDS----------QRNTCRRII------NVDIRFP----------SFVTPLARDLILRLLQKDPAKRMP----------LNQVRSHPWI
|.|.| |||  |.          .  .  .|.      | ...||          ....| |.||| .||.|||.||             .....||| 
EMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNHPWF
Kinase 81997.m00106.AA S_TKc 38-288 36 4.8e-103 349.57 SMART 1-231 (231) Show / Hide 
Range on Protein: 38-288
Range on HMM: 1-231/231
Sequence Identity: 36% (97 aa)

FEIGRPLGTGKFGRVYLAREAKSKFIVGIKVLNKAQLQKASIEHQLRREIEIQSHLRHPNIIRLYGYFYDATRICLIIEYAAR--GELFSILRDAGR---
.||.|..| | ||.||..|. |.. || ||...           ..||||.| .. .||||..||..|.| ...... ||.    |.||..... ||   
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

---FDEHTAAEYIVQMCDAIDYCHSKHIIHRDIKPENILVGLNGELKIADFGWSVHAPTSRRTTLCGTLDYLPPEMIEGHDHDK-SVDIWTLGVLLYEFL
   |.| .|. |. |.|.|..||||..|||||.||||||.    ..||.||| . .      ||.|||..|..||..    ..| ..|.| .|..|||.|
RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-----TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEML

VGEPPFETDSQRNTCRRIINVDIRFPSFVTPLARDLILRLLQKDPAKRMPLNQVRS-------HPWI
.|.|||.   .  . ..|           .| |.|.| ..|||||.||.   ..         |||.
CGYPPFP--QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 81997.m00106.AA CAMK 43-288 23 5.6e-99 319.6 In-house 1-425 (425) Show / Hide 
Range on Protein: 43-288
Range on HMM: 1-425/425
Sequence Identity: 23% (100 aa)

PLGTGKFGRVYLAREAKSK------------FIVGIKVLNKAQLQK-------------------------ASIEHQLRREIEIQSH-------LRHPNI
 ||.| || |.|... ...              | ||...| .|..                         .. ....|||||| ..       |.||||
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

IRLYGYFYDAT-------------------RICLII---EYAARGEL----FSILRDA---------------GRFDEHTAAEYIVQMCDAIDYCHSKHI
|.|| .. |..                   .....    ||.  |||    |. ...                |||.|. |. |. |.|.|..||||..|
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNI

IHRDIKPENILVGLN-----------------GELKIADFGWSVHAPTSR-------------------------RTTLCGTLDYLP-PEMIEG------
.|||.||||||.  |                 . .||.||| . . . .                           .| |||. | . ||...|      
VHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNM

--------HDHDKSVDIWTLGVLLYEFLVGEPPFETD-------------SQRNTCRRIINVDIRFPSF------------------------VTPLARD
          .....|.| .||.||  |.|.|||. |             ........|.. . .||..                        |.. ..|
QNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECKD

LILRLLQKDPAKRMPLNQVRSHPWI
|| ..||.|| ||| . |. .|||.
LIRKMLQVDPEKRMTIEQCLNHPWM
Kinase 81997.m00106.AA CAMKL 38-288 34 8e-95 303.03 In-house 1-297 (297) Show / Hide 
Range on Protein: 38-288
Range on HMM: 1-297/297
Sequence Identity: 34% (103 aa)

FEIGRPLGTGKFGRVYLAREAKS-KFIVGIKVLNKAQLQKASIEHQ------------LRREIEIQSHLR---HPNIIRLYGYFYDATR------ICLII
..||. ||.| || | ||.  .  .  | ||...|  ...  . ..            .||||.|...|.   |||||.||  ... .       |.|. 
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVM

EYAARGE--LFSILRDA----GRFDEHTAAEYIVQMCDAIDYCHSKHIIHRDIKPENILVGLNG--ELKIADFGWS-----V-HAPTSRRTTLCGTLDYL
||.  ||  ||  ..      ||..|| |  |  |...|..||||..|.||||||||||.  ||   .||.||| |     .   |    .| ||.. | 
EYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPYM

PPEMIEG-HD-HD-KSVDIWTLGVLLYEFLVGEPPFETDS-------QRNTCRRIINVDIRFPS---FVTPLARDLILRLLQKDPAKRMPLNQVRSHPWI
.||...| .. .| . |||| .||.||  ..|. ||. |.          . ...|...  .|    .|   .|||| ..||..| ||. . |...||| 
APEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMNHPWM
Kinase 81997.m00106.AA Pkinase 38-288 34 5.5e-89 306.73 Pfam 1-293 (293) Show / Hide 
Range on Protein: 38-288
Range on HMM: 1-293/293
Sequence Identity: 34% (101 aa)

FEIGRPLGTGKFGRVYLAREAKSKFIVGIKVLNKAQLQKASIEHQLRR--EIEIQSHLRHPNIIRLYGYFYDATRICLIIEYAARG----ELFSILR--D
..|||..| | ||.||.... ..  || .|...|   .| . . ..||  ||.|  .|.||||.|||..|.| ..|... ||.  |    .||....  .
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKR-HEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWR

AGRF--DEHTAAEYIVQMCDAIDYCHSKHIIHRDIKPENILVGLNGEL----KIADFGWSV---HAPTSRRTTLCGTLDYLPPEMIE-GHDHDKSVDIWT
 |.|  .|...  |. |.. ...||||. |||||.||||||.  ||..    ||.||| .    . . |  ||.|||..|..|| |  | .....||.| 
HGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWS

LGVLLYEFLVGEPPFETD------SQRNTCRRIINVDIRFPSFVT---------------------PLARDLILRLLQKDPAKRMPLNQVRSHPWI
.|..|||.| |.|||  .      .|.   .||   ...|... .                     . ..|.| ..|.|||.||    |.  |||.
CGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase 81997.m00106.AA MARK 38-288 37 1.7e-88 289.42 In-house 1-262 (262) Show / Hide 
Range on Protein: 38-288
Range on HMM: 1-262/262
Sequence Identity: 37% (97 aa)

FEIGRPLGTGKFGRVYLAREAKSKFIVGIKVLNKAQLQKASIEHQLRREIEIQSHLRHPNIIRLYGYFY--DATR-ICLIIEYAARGELFSILRDA--GR
..... .|.| .. |.||.  ...  | ||...| .|..      ..||||| ..| |||||.|. ..   . .. |.|| ||| .|||.. .. .  ||
YKMLKTIGHGSYAKVKLACHKHTGRKVAIKIYEKFKLNDPQWMKNVMREIEIMKKLDHPNIIKLFHVIEQDTEQHQIYLIMEYASGGELYDYIKAHPNGR

FDEHTAAEYIVQMCDAIDYCHSKHIIHRDIKPENILVGLNG--ELKIADFGWSVHAPTSR-RTTLCGTLDYLPPEMIEGHDHD-KSVDIWTLGVLLYEFL
  |  |  .  |.. |. |||||.|.||||||||||.  ||    ||.|||.|.. |. .  .| |||. | .||.... . | . ||||.|||.||  .
LHEEEARRIFRQIVSAVNYCHSKNIVHRDIKPENILIDENGNHNIKIIDFGFSICIPPGQKLNTFCGTPPYMAPEIFLKKPYDGPKVDIWSLGVVLYFMV

VGEPPFETDS--QRNTCRRIINVDIRFPSFVTPLARDLILRLLQKDPAKRMPLNQVRSHPWI
.|  ||. |.  . .  ..| . . ..|..| . .|.|| |||. .| .|. . .. .|||.
CGYFPFDGDTQDYKELYKKILRGKYDIPCHVSKECRNLIQRLLTVNPEERPTIEEIMKHPWM
Kinase 81997.m00106.AA Ciliate-E2 38-288 26 5.8e-81 275.28 In-house 1-365 (365) Show / Hide 
Range on Protein: 38-288
Range on HMM: 1-365/365
Sequence Identity: 26% (99 aa)

FEIGRPLGTGKFGRVYLAREAKSK-----------------------FIVGIKVLNKAQLQKASIEHQLRREIE----------IQSHLRHPNIIRLYGY
... . .|.| || ||...  | .                       .|. .|...| |..  . | .. |||.          |...| |||||..| .
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

FY--DATRICLIIEYAARGELFSILR------------DAGRFDEHTAAEYIVQMCD---------------AIDYCHSKH-IIHRDIKPENILVGLNGE
|.  | . | |. ||.  |.||....            | ..|.|  ..... | ..               |. |.|||. ||||||||||||.     
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKD-KYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----

LKIADFGWSVHAPTSRR---------------------------------TTLCGTLDYLPPEMIE---------GHDHDKSVDIWTLGVLLYEFLVGEP
.||.||| |  . ...                                   |.|||. |..||...         ....|...||| |||.|||.| |.|
IKIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKP

PFETDSQRNTCRRIINV-DIRFPSF------------------VTPLARDLILR----LLQKDPAKRMP-LNQVRSHPWI
||          ..|   .|.||..                  ... . ||| .    .||||| ||.   .|.  |||.
PF---------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase 81997.m00106.AA PKA 38-288 39 7.4e-77 261.64 In-house 1-263 (263) Show / Hide 
Range on Protein: 38-288
Range on HMM: 1-263/263
Sequence Identity: 39% (105 aa)

FEIGRPLGTGKFGRVYLAREAKSKFIVGIKVLNKAQLQKASIEHQLRREIEIQSHLRHPNIIR-LYGYFYDATRICLIIEYAARGELFSILRDAGRFDEH
||| . |||| ||||.|.|. .|. .. .|.|.|..  .   ..    |. | . ..||.|.. .|. | |.. . .. ||.. ||.|| ||  |||.. 
FEIIQTLGTGSFGRVMLCRHKHSGNYYAMKMLKKQEIVRLKQVEHVHNEKNILQNIKHPFIVKKMYWTFQDDRYLYMVMEYVPGGEMFSYLRKSGRFSNP

TAAEYIV-QMCDAIDYCHSKHIIHRDIKPENILVGLNGELKIADFGWSVHAPTSRRTTLCGTLDYLPPEMIEGH-DHDKSVDIWTLGVLLYEFLVGEPPF
.|  |.  | . |..| ||..||.|| ||||||   || .||.||| .    . |  ||||| .||.||.| ..  | |||| |.||.| ||.|.| |||
HAKFYAASQIVLALEYLHSQNIIYRDLKPENILIDKNGHIKITDFGFAKKVDD-RTWTLCGTPEYLAPEIIQSKNGHGKSVDWWALGILIYEMLAGYPPF

ETD--SQRNTCRRIINVDIRFPSFVTPLA---RDLILRLLQKDPAKRM-----PLNQVRSHPWI
. .  ..  . ..|.| .|.||..... |   .||| .|||.|. ||        |... |.| 
YDHNRDPMQIYEKICNGKIKFPRHFDSDANYFKDLIKKLLQVDLTKRYGNMKNGVNDIKNHKWF
Kinase 81997.m00106.AA RSK 41-288 32 1.8e-73 250.38 In-house 1-278 (278) Show / Hide 
Range on Protein: 41-288
Range on HMM: 1-278/278
Sequence Identity: 32% (90 aa)

GRPLGTGKFGRVYLAREA---KSKFIVGIKVLNKAQLQKAS--IEHQLRREIEIQSHLR-HPNIIRLYGYFYDATRICLIIEYAARGELFSILRDAGR--
 . ||.| .| |.| |.    ... |   |||.|| . ..   ..|  ..|..| .. . ||.|..|.  | . . . || ||   ||||  |.  ..  
LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRH-TMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFG

-FDEHTAAEYIVQMCDAIDYCHSKHIIHRDIKPENILVGL---NGELKIADFGWSVHAPTS---RRTTLCGTLDYLPPEMIE----GHDHDKSVDIWTLG
 |.|..|..|. .   |... |...|||||.||||||      .|..|. ||| .  .. .   .  | |.|..|..|||.     .  |||..|.|.||
CFSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDESNEGHIKLTDFGFCKQFRCDHNQWTMTFCYTIEYMAPEMLKRANQQGGHDKACDWWSLG

VLLYEFLVGEPPFET---DSQRNTCRRIINVD--IRFP--SFVTPLARDLILRLLQKDPAKRMP-----LNQVRSHPWI
||.|| |.| |||     ...  . .|| . .   ..|  ..... |.||| ..|..||.||       ......|||.
VLMYEMLTGCPPFQGPNDNNRKEIMKRIQKGKFSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF
Kinase 81997.m00106.AA Ciliate-E2-Unclassified 38-288 25 2.3e-71 243.4 In-house 1-352 (352) Show / Hide 
Range on Protein: 38-288
Range on HMM: 1-352/352
Sequence Identity: 25% (89 aa)

FEIGRPLGTGKFGRVYLAREAKSKFIVGIKVLNKAQLQK-----ASIEHQLRREIEIQSH----------------LRHPNIIRLYGYFYDATR--ICLI
..|.. .|.| || ||.... | |..  .| ..|.| .|      ..   .. ..|....                | ||...... .... ..  |...
YKIIKQIGQGGFGKVYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKD-EIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIV

IEYAARGELFSILRD-----------------AGRFDEHTAA-----EYIVQMCDAIDYCHSKH-IIHRDIKPENILVGLNG---ELKIADFGWSVHA--
 ||.  |.|. ....                   .|.|  |.      |. | .....|.|.|. ||||||||||||.  ||   ..||.||| | .   
MEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQ

---------------PTSRRTTLCGTLDYL----PPEMIEGHDHD----KSVDIWTLGVLLYEFLVGEPPFE-TDSQR---------------NTCRRII
               .  . .| |||. |.    .||...|. .|    ...|||.|||.|||.| |..||. ...                 .  . |.
NNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNIK

NVDIRFPS--------FVTPLARDLIL----RLLQKDPAKRMPLNQVRSHPWI
. .| ||.         . | | |.|     ..|.|.| ||. ..|.  |||.
QKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase 81997.m00106.AA AktR 38-288 33 1e-70 241.27 In-house 1-268 (268) Show / Hide 
Range on Protein: 38-288
Range on HMM: 1-268/268
Sequence Identity: 33% (90 aa)

FEIGRPLGTGKFGRVYLAREA-KSKFIVGIKVLNKAQLQKASIEHQLRREIEIQS-HLRHPNIIRLYGYFYDATRICLIIEYAARGELFSILRDAGRFDE
|.. ..|| |.||.|||...  ... .. .|.. |  ...   .|....|  |   . .|| |..|.  | . . . .|.|| ..||||..|.  ..|.|
FHVYKCLGKGAFGKVYLVQKKRDNQKQYAMKMIKKKKIIERNQMHHTITERNIMEMCCNHPFIVKLHYCFQTKEKLFFIMEYCPGGELFQHLKKKKKFSE

HTAAEYIVQMCDAIDYCHSK-HIIHRDIKPENILVGLNGELKIADFGWSV----HAPTSRRTTLCGTLDYLPPEMIEG-HDHDKSVDIWTLGVLLYEFLV
 .|  |..|.. |..| |.. .|| ||.|||||| ...| .||.||| |      . . . ...|||  |..||||     |.||||.|..|...|| ..
EQARFYFAQILLALEYLHQHMNIIYRDLKPENILLDEDGHVKITDFGLSKLQFMMHYDEKAYSFCGTPEYMAPEMITKKKGHNKSVDWWAFGIFIYEMVT

GEPPFETDSQRNTCRRIINVD---IRFPSFVTPLARDLIL-RLLQKDPAKRMP-----LNQVRSHPWI
| |||. ..|.    .|.. .   . .|| ... ..|||  .||.|.| ||         ...|||| 
GCPPFYHKNQNQMFQKIKIKQQNKFPYPSYFSSQCKDLIQRKLLCKNPNKRLGYYCNGWEEIKSHPWF
Kinase 81997.m00106.AA Pkinase_Tyr 38-181 31 3.8e-27 92.55 Pfam 1-156 (270) Show / Hide 
Range on Protein: 38-181
Range on HMM: 1-156/270
Sequence Identity: 31% (49 aa)

FEIGRPLGTGKFGRVYLAREA----KSKFIVGIKVLNKAQLQKAS-IEHQLRREIEIQSHL-RHPNIIRLYGYFY-DATR--ICLIIEYAARGELFSILR
 ..|. || | ||.||...      . |  | .|.| | .  .   .   . ||..| ..| .||||.||||  . .     |... ||.. | | . ||
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR

D----AGRFDEHTAAEYIVQMCDAIDYCHSKHIIHRDIKPENILVGLNGELKIADFG
.     .... ..  .. .| ... .| .||..||||.   |.||. |.  ||.|||
KHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFG
Kinase 81997.m00106.AA TyrKc 38-292 21 1.2e-17 62.9 SMART 1-280 (280) Show / Hide 
Range on Protein: 38-292
Range on HMM: 1-280/280
Sequence Identity: 21% (64 aa)

FEIGRPLGTGKFGRVYLAREAKSKFIVGIKVLNKAQLQKASIEHQLRREIEIQSHL--RHPNIIRLYGYFYDA-------TRICLIIEYAARGELFSILR
 . |. || | ||.||...       | .|.|..        .  ..||..| ..|  .||||.||||.  .          .... ||.. | | . ||
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR

DAGR-FDEHTAAEYIVQMCDAIDYCHSKHIIHRDIKPENILVGLNGELKIADFGWSVHAPTS-------RRTTL----CGT----LDYLPPEMIEGHDHD
. .. .   .  .. .| ..  .| |||..||||.   |.||| |.  ||.||| |                .     .|     .  ..|| |  .   
KHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFT

KSVDIWTLGVLLYEFL-VGEPPFET-----DSQRNTCRRIINVDIRFPSFV---------TPLARDLILRLLQKDPAKRMPLNQVRSHPWIVQQL
   |.|  ||...| .  |..| .       | .   ... . . . .            ..   .....  . ||..|   ...      ....
TKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI------HECF