Gene 96830.m00065 (T.vaginalis)

96830.m00065

Species: T.vaginalis
Alias: 96830.m00065, TvagK0441
External Links:
Annotation:

Classification

Group: AGC
Family: MAST
Subfamily: MAST

Sequence

Name Sequence Type Origin Length Description Download
96830.m00065.AA Protein None 730 None Fasta, JSON
96830.m00065.kin_dom Protein Kinase Domain None 267 None Fasta, JSON

Protein domain

Protein domains of 96830.m00065.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 96830.m00065.AA AGC 336-602 28 3.5e-137 357.0 In-house 1-395 (395) Show / Hide 
Range on Protein: 336-602
Range on HMM: 1-395/395
Sequence Identity: 28% (114 aa)

FEFIRRISSGAFATVFIAKKK------LTGDIFAIKVIPRTT-VIQKN--QTSRIMTE------------KDILKNFT----------NPYIVT-FYYSI
|||.. |. |.| .|. ..||       ||...|.||.   . ...|.  .  ..|||            ..||..            .|.||   .|| 
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF

LGERN--LYLVTEFVP---------GG-DLYSLLQ---ALGSFDEDSSKIYIAE-------ILHALRYLRE-NGIIHRD-LKPDNILVTKNGTLKLTDFG
  ...  ||.| |..|         || .|.. ||     |.|||. ...|.||       |. || || . .|||||| |||.||| ...| .||||||
QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG

LSHQGIVNR--------------------------QMSNEPEDIEAEP----------------EIVG--TLDYMAPEILMNLPHSFGVDYWS--LGAML
|. .|. ..                          .   .|. . ..                  ..|  | .|||||||    ... .|.||  ||...
LCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNK-CNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL----YGKACDWWSFGLGCLM

FEFLTGVPPFHADTDT----------ETTKNIL------LNKIDFQPD--------DEMSPEAKDLIKRLLDPNPETRLGVKD-------INDIFKNPWL
.|.||| |||..|..           |. ..|.       .|. | ..        ...|||||||||.|| ..|| ||| ..       ...| . || 
YEMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNHPWF
Kinase 96830.m00065.AA MAST 336-589 36 6.5e-109 352.29 In-house 1-320 (334) Show / Hide 
Range on Protein: 336-589
Range on HMM: 1-320/334
Sequence Identity: 36% (117 aa)

FEFIRRISSGAFATVFIAKKKLTGDIFAIKVIPRTTVIQKNQTSRIMTEKDILKNFTNPYIVTFYYSILGERNLYLVTEFVPGGDLYSLLQALGSFDEDS
||||. || ||.  |. .|.| |.|.||.|||     | ||...  ..|..||.. .||..| ..||   ...|..| |.. |||. |||...|.|||. 
FEFIKPISKGAYGKVYLVKHKKTNDRFAMKVIKKSDMINKNMVDQVQVERNILAMYQNPFVVKMFYSFQTKNYLCMVMEYMEGGDCASLLHMYGYFDEWM

SKIYIAEILHALRYLRENGIIHRDLKPDNILVTKNGTLKLTDFGLSHQGIVN-------------------------RQMSNE-----------------
 |.||||.  .| || . ||.||||||||.| ..||  ||||||||  |...                         .|.  .                 
AKMYIAETVLCLEYLHSHGIVHRDLKPDNMLIDSNGHIKLTDFGLSKVGFMDDLNMMYEGYTPPNIFNNSTDPMNKNQQDYSQFPGDFGINGNTNKNQIQ

--------------PEDIEAEPEIVGTLDYMAPEILMNLP-HSFGVDYWSLGAMLFEFLTGVPPFHADTDTETTKNILLNK---IDFQPD------DEMS
              |. |.    ..||.||.|||.. . . |.  ||.||.| ...|||.|.|||  || .|.  |||  .   | . ..      ..||
QQQEQPQCQQQNMRPHNIHQNKQCCGTPDYIAPEVILGQGTHGKPVDWWSMGIIMYEFLVGCPPFNDDTPEEIFQNILNRNCNEIEWPEGGDINDDEAMS

PEAKDLIKRLLDPNPETRLG
|||.|||..||.|.|..|||
PEAQDLIEKLLQPDPRKRLG
Kinase 96830.m00065.AA S_TKc 336-602 33 1.1e-94 321.85 SMART 1-231 (231) Show / Hide 
Range on Protein: 336-602
Range on HMM: 1-231/231
Sequence Identity: 33% (93 aa)

FEFIRRISSGAFATVFIAKKKLTGDIFAIKVIPRTTVIQKNQTSRIMTEKDILKNFTNPYIVTFYYSILGERNLYLVTEFVPG--GDLYSLLQALGS---
.|..| | .|||..|. ...| || |.|||.|.           .|. | .|||.   |.||..|...    .||.|.|...|  |||.....  |.   
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

---FDEDSSKIYIAEILHALRYLRENGIIHRDLKPDNILVTKNGTLKLTDFGLSHQGIVNRQMSNEPEDIEAEPEIVGTLDYMAPEILMNLPHSF-GVDY
   |.|   . |...|. || |. ..|||||||||.|||...  ..|..||||. |                   ..||..|||||.|   ....  .| 
RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL----------------TTFCGTPWYMAPEVL---GYGKCKCDW

WSLGAMLFEFLTGVPPFHADTDTETTKNILLNKIDFQPDDEMSPEAKDLIKRLLDPNPETRLGVKDIND----IFKNPWL
||.| .|.|.|.| |||.  .. .. |.|.            ||||||.|...|. .|| |... ..      | . ||.
WSCGCILYEMLCGYPPFP--QMQMMFKKIG------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 96830.m00065.AA RSK 339-602 35 1.1e-86 294.27 In-house 1-278 (278) Show / Hide 
Range on Protein: 339-602
Range on HMM: 1-278/278
Sequence Identity: 35% (102 aa)

IRRISSGAFATVFIAKKK---LTGDIFAIKVIPRTTVIQKNQ-TSRIMTEKDILKNFT-NPYIVTFYYSILGERNLYLVTEFVPGGDLYSLLQALGS---
..    |..  ||. .|.    || |.| ||. . ...|..  | . ||| .||.  .  | ||| .|.   |  |||..|...||.|.  ||  ..   
LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFGC

FDEDSSKIYIAEILHALRYLRENGIIHRDLKPDNILVTK---NGTLKLTDFGLSHQGIVN---RQMSNEPEDIEAEPEIVGTLDYMAPEILM---NLP-H
|.||  ..|.|||  |...| . |||||||||.||| .    .|..||||||.. |.  .   . |.            ..|..|||||.|.       |
FSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDESNEGHIKLTDFGFCKQFRCDHNQWTMT-----------FCYTIEYMAPEMLKRANQQGGH

SFGVDYWSLGAMLFEFLTGVPPFHA---DTDTETTKNILLNKIDFQPD--DEMSPEAKDLIKRLLDPNPETRLG--VKDINDIFKNPWL
.  .|.||||. ..| ||| |||..   ..  |. |.|. .|...  .  ...|.||||||...|  .|. |||   .|...| ..||.
DKACDWWSLGVLMYEMLTGCPPFQGPNDNNRKEIMKRIQKGKFSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF
Kinase 96830.m00065.AA Akt 336-602 37 1.1e-83 267.42 In-house 1-264 (264) Show / Hide 
Range on Protein: 336-602
Range on HMM: 1-264/264
Sequence Identity: 37% (103 aa)

FEFIRRISSGAFATVFIAKKKLTGDIF-AIKVIPRTTVIQKNQTSRIMTEKDILKNFTNPYIVTFYYSILGERNLYLVTEFVPGGDLYSLLQALGSFDED
|.|.. . .|.|. || .||| |.... |.||.     |||||   ..||. ||..  .|.||  .||   . .||.|.....||.|...||  . |.||
FDFLKVLGKGSFGKVFLVKKKDTQKWYYAMKVLKKDYIIQKNQVEHTKTERNILQHCNHPFIVNLHYSFQTQDKLYFVMDYCNGGELFYHLQRKRRFSED

SSKIYIAEILHALRYLRENGIIHRD-LKPDNILVTKNGTLKLTDFGLSHQG-IVN--RQMSNEPEDIEAEPEIVGTLDYMAPEILMNLPHSFGVDYWS-L
  . |.|||  |. .| ...|| || ||| |||. |.| ..||||||. .. | .  . ..           . ||  |.||||| .  |.  || |. |
RARFYCAEIILAIEHLHSKNIIYRDYLKPENILMDKDGHICLTDFGLCKENIIKDHDKTKT-----------FCGTPEYLAPEILNGNGHTKAVDWWGSL

GAMLFEFLTGVPPFHADTDTETTKNILLNKIDFQPDDEMSPEAKDLIKRLLDPNPETRLG--VKDINDIFKNPWL
|. ..|...| |||...   .  |.|. ... | . |  |||.||||..||  .|. |||   .|...|   ||.
GCVMYEMMCGRPPFYNQDHHQMFKKIKNQPVKFPDKDWISPECKDLISGLLNKDPKKRLGGGPNDAQEIKRHPWF
Kinase 96830.m00065.AA Ciliate-E2 336-602 25 1.1e-81 277.69 In-house 1-365 (365) Show / Hide 
Range on Protein: 336-602
Range on HMM: 1-365/365
Sequence Identity: 25% (98 aa)

FEFIRRISSGAFATVFIAKKKLTGDIFAIKVIPRTT------------------VIQKNQTSRIMTEKDILK----------------NFTNPYIVTFYY
..||. | .|.|..|. .|.....  ||||.|  .                   ...|||   |. |..|..                .  .|.|. .|.
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIID-QKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYE

SIL--GERNLYLVTEFVPGGDLYSLLQ------------ALGSFDEDSSKIYIAEILH---------------ALRYLRENG-IIHRDLKPDNILVTKNG
.     . |.|||.|.. ||||.....            . ..|.|   | ....||                ||.|| ... |||||.||.|||.    
CFQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKD-KYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF----

TLKLTDFGL-----------SHQGIVNRQMSNEPEDIEAEPE-------------IVGTLDYMAPEILMNLP---------HSFGVDYWSLGAMLFEFLT
 .|..||||           .| .  .  . .   |..  |              |.||. |||||||.. .         ... .|.|||| .|.|.|.
-IKIIDFGLSKKYDDDNQNRTH-KQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLF

GVPPFHADTDTETTKNILLNKIDFQPD----------------DEMSPEAKDLIKR----LLDPNPETRLGVKDINDIFKNPWL
| |||         ..|. .||||..                 .. |.|.|||||.    .|. .|| |..  ....|...||.
GKPPF--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRIT--GWEQILNHPWF
Kinase 96830.m00065.AA Pkinase 336-602 29 9.2e-80 276.1 Pfam 1-293 (293) Show / Hide 
Range on Protein: 336-602
Range on HMM: 1-293/293
Sequence Identity: 29% (89 aa)

FEFIRRISSGAFATVFIAKKKLTGDIFAIKVIPRTTVIQKNQTSRIM-TEKDILKNFTNPYIVTFYYSILGERNLYLVTEFVPGG----DLYSLLQ--AL
....|.| ||.|..|.....| ||.|.|.|.|.. .   . . ...  .|  |.|..  |.||..|..   ....|.|.|...||    ||.....  . 
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

GSF--DEDSSKIYIAEILHALRYLRENGIIHRDLKPDNILVTKNGTL----KLTDFGLSHQGIVNRQMSNEPEDIEAEPEIVGTLDYMAPEILM-NLPHS
|.|  .|.  | |. .|| .| |. ..|||||||||.|||. .||..    |..||||. |              .    ..||..|||||... . ...
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD--------Y-NNS-MTTFCGTPWYMAPEVIRGGQYYG

FGVDYWSLGAMLFEFLTGVPPFHAD------TDTETTKNILLNKIDFQPDDE-------------------MSPEAKDLIKRLLDPNPETRLGVKDINDI
  || ||.| .|.|.|.| |||  .      .. .  ..|.  ...|. . .                   .|.|.||.||..|...|. |..   . .|
PKVDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPT---AEQI

FKNPWL
.. ||.
LQHPWF
Kinase 96830.m00065.AA AktR 336-602 32 1.7e-77 263.77 In-house 1-268 (268) Show / Hide 
Range on Protein: 336-602
Range on HMM: 1-268/268
Sequence Identity: 32% (91 aa)

FEFIRRISSGAFATVFIAKKK-LTGDIFAIKVIPRTTVIQKNQTSRIMTEKDILK-NFTNPYIVTFYYSILGERNLYLVTEFVPGGDLYSLLQALGSFDE
|.... . .|||..|. ..||  .....|.|.|  .. |..|| ... ||..|..    .| || ..|..  ...|... |..|||.|.. |.  . |.|
FHVYKCLGKGAFGKVYLVQKKRDNQKQYAMKMIKKKKIIERNQMHHTITERNIMEMCCNHPFIVKLHYCFQTKEKLFFIMEYCPGGELFQHLKKKKKFSE

DSSKIYIAEILHALRYLREN-GIIHRDLKPDNILVTKNGTLKLTDFGLSH-QGIV-NRQMSNEPEDIEAEPEIVGTLDYMAPEILMN-LPHSFGVDYWSL
. ...|.|.|| || || ..  || |||||.|||  ..| .|.||||||  |..  .... .          ..||  |||||....  .| . ||.|..
EQARFYFAQILLALEYLHQHMNIIYRDLKPENILLDEDGHVKITDFGLSKLQFMMHYDEKAY---------SFCGTPEYMAPEMITKKKGHNKSVDWWAF

GAMLFEFLTGVPPFHADTDTETTKNILLNK-IDFQPDDEMSPEAKDLIK-RLLDPNPETRLG--VKDINDIFKNPWL
|. ..| .|| ||| .. ...  ..|.    . |..  . |...||||. .||. ||. |||   ... .| . || 
GIFIYEMVTGCPPFYHKNQNQMFQKIKIKQQNKFPYPSYFSSQCKDLIQRKLLCKNPNKRLGYYCNGWEEIKSHPWF
Kinase 96830.m00065.AA MAST 336-489 45 1.4e-72 220.89 In-house 1-157 (337) Show / Hide 
Range on Protein: 336-489
Range on HMM: 1-157/337
Sequence Identity: 45% (71 aa)

FEFIRRISSGAFATVFIAKKKLTGDIFAIKVIPRTTVIQKNQTSRIMTEKDILKNFTNPYIVTFYYSILG--ERNLYLVTEFVPGGDLYSLLQALG-SFD
||||. || ||.  |. .|.| |.|.||.|||   . | |||   .. |..||.. .||..| ..||     .. |..| |.. |||  |||...| ...
FEFIKCISKGAYGAVYLVKHKKTNDRFAMKVINCQDTIDKNQVDQVFVERNILTMYQNPFVVKMFYSFQTPCKKYLCMVMEYMEGGDCASLLRMYGNCMP

EDSSKIYIAEILHALRYLRENGIIHRDLKPDNILVTKNGTLKLTDFGLSHQGIVNRQ
|.  |.||||.  .| || . ||.||||||||.| ..|| .||||||||  |.....
EWMAKMYIAETVLCLEYLHSYGIVHRDLKPDNMLIDSNGHIKLTDFGLSKVGFMDKT
Kinase 96830.m00065.AA NDR 336-498 39 1.8e-62 191.21 In-house 1-168 (350) Show / Hide 
Range on Protein: 336-498
Range on HMM: 1-168/350
Sequence Identity: 39% (67 aa)

FEFIRRISSGAFATVFIAKKKLTGDIFAIKVIPRTTVIQKNQTSRIMTEKDILKNFT--NPYIVTFYYSILGERNLYLVTEFVPGGDLYS---LLQALGS
||.|. |..|||  |....|| ||.|.|.|..  .....|||.  . .|.||.      ||..|  |||   . .|||| |..||||. .   ||. .. 
FEIIKIIGKGAFGEVWLVRKKDTGHIYAMKIMRKSEMMWKNQVAHVRAERDIMAEADNKNPWVVKLYYSFQDKQYLYLVMEYHPGGDMMTYCYLLMKMDI

FDEDSSKIYIAEILHALRYLRENGIIHRDLKPDNILVTKNGTLKLTDFGLSHQGIVNRQMSNEPEDIE
|.||  . ||||.  |. .. ..|.||||.||||.|. | | .|||||||. .|.  | . .   ...
FTEDWARFYIAEMVCAIESVHKMGYIHRDIKPDNFLIDKDGHIKLTDFGLCTGGMIRRHWKQNKQKKP
Kinase 96830.m00065.AA SGK 336-485 35 7.6e-54 164.42 In-house 1-176 (283) Show / Hide 
Range on Protein: 336-485
Range on HMM: 1-176/283
Sequence Identity: 35% (62 aa)

FEFIRRISSGAFATVFIAKKKLT------------------GDIFAIKVIPRTTVI-------QKNQTSRIMTEK-DILKNFTNPYIVTFYYSILGERNL
|.|.  |  | |  |. .|.| .                  ....|.||. . ..|       .|..   ||.|. .||||.  | ||   |.   .  |
FDFLKVIGKGSFGKVYQVKHKDDETCQRVWLIFQSLLSQSEDKFYAMKVLQKQHIINEYRQDLKKKEQKHIMAERNVILKNMKHPFIVNLHYAFQTKWKL

YLVTEFVPGGDLYSLLQALGSFDEDSSKIYIAEILHALRYLRENGIIHRDLKPDNILVTKNGTLKLTDFGLSHQGI
|.| ..| ||.. . ||  ..| || ...| |||  || || .  ||.|||||.|||    | ..||||||. .||
YFVMDYVNGGEMFYHLQREKHFPEDRARFYAAEIVCALEYLHSQDIIYRDLKPENILLDHQGHCCLTDFGLCKEGI
Kinase 96830.m00065.AA PKA 336-479 40 9.7e-52 178.2 In-house 1-146 (263) Show / Hide 
Range on Protein: 336-479
Range on HMM: 1-146/263
Sequence Identity: 40% (59 aa)

FEFIRRISSGAFATVFIAKKKLTGDIFAIKVIPRTTVIQKNQTSRIMTEKDILKNFTNPYIVT-FYYSILGERNLYLVTEFVPGGDLYSLLQALGSFDED
||.|. . .| |..|  ...| .|...|.|.. ...... .|. ....|| ||.| ..|.||.  |..   .|.||.| |.||||.. | |.. |.|...
FEIIQTLGTGSFGRVMLCRHKHSGNYYAMKMLKKQEIVRLKQVEHVHNEKNILQNIKHPFIVKKMYWTFQDDRYLYMVMEYVPGGEMFSYLRKSGRFSNP

SSKIYIA-EILHALRYLRENGIIHRDLKPDNILVTKNGTLKLTDFG
 .|.|.| .|  || ||    ||.||||| |||  ||| .|.||||
HAKFYAASQIVLALEYLHSQNIIYRDLKPENILIDKNGHIKITDFG
Kinase 96830.m00065.AA NDR 503-602 39 2.3e-41 124.88 In-house 241-350 (350) Show / Hide 
Range on Protein: 503-602
Range on HMM: 241-350/350
Sequence Identity: 39% (43 aa)

IVGTLDYMAPEILMN-LPHSFGVDYWSLGAMLFEFLTGVPPFHADTDTETTKNILLNKIDF------QPDDE-MSPEAKDLIKRLLDPNPETRLGVKD--
.||| ||||||....   ... .|.||||....|.|.|.|||..|| .|| ..|.  |. .      .| .. .||||.|||.||. |.|..|||..   
TVGTPDYMAPEVFQQKTGYNQTCDWWSLGCIMYEMLVGYPPFCSDTPQETCMKIMNWKQTWDWPMTHFPPEANLSPEAWDLIRRLCCPDPDHRLGSHGKG

INDIFKNPWL
. .| . |. 
VDEIKSHPFF
Kinase 96830.m00065.AA MAST 503-589 44 1.1e-37 112.2 In-house 228-324 (337) Show / Hide 
Range on Protein: 503-589
Range on HMM: 228-324/337
Sequence Identity: 44% (43 aa)

IVGTLDYMAPEILMNLP-HSFGVDYWSLGAMLFEFLTGVPPFHADTDTE-TTKNILL--NKIDFQPD------DEMSPEAKDLIKRLLDPNPETRLG
..|| ||.|||..   . ..  ||.||.| ...|||.|.||| .||  | .  ||.   ..| . ..      |.|||||.||||.||.||| .|||
CCGTPDYIAPEVILGQGTYGKPVDWWSMGIIMYEFLVGCPPFNGDTPEEMIFQNIINHDREIEWPEEGDPNDDDCMSPEAQDLIKKLLQPNPKKRLG
Kinase 96830.m00065.AA SGK 505-602 39 3e-29 87.09 In-house 187-283 (283) Show / Hide 
Range on Protein: 505-602
Range on HMM: 187-283/283
Sequence Identity: 39% (39 aa)

GTLDYMAPEILMNLPHSFGVDYWSLGAMLFEFLTGVPPFHADTDTETTKNILLNKIDFQPDDEMSPEAKDLIKRLLDPNPETRLGVK-DINDIFKNPWL
||. |.|||.|   ||.  || |.||. |.|...| |||      .   ||.  .. . |   ||..|.|||. ||  .|. ||| | |  .| . |. 
GTPEYLAPEVLRKQPHDRTVDWWCLGCVLYEMMYGLPPFYSRNKQQMYDNIINQPLQIPP--QMSNDAWDLIQGLLQKDPKKRLGTKRDFMEIKNHPFF
Kinase 96830.m00065.AA PKA 505-602 34 2.7e-22 80.42 In-house 160-263 (263) Show / Hide 
Range on Protein: 505-602
Range on HMM: 160-263/263
Sequence Identity: 34% (37 aa)

GTLDYMAPEILMNL-PHSFGVDYWSLGAMLFEFLTGVPPFHAD--TDTETTKNILLNKIDFQPDDEMSPEA---KDLIKRLLDPNPETRLGVKDI--NDI
|| .|.||||. .  .|  .|| |.||   .|.|.|.||| ..  .  .. . |.  ||.|..  .... |   |||||.|| .... |.| ..   |||
GTPEYLAPEIIQSKNGHGKSVDWWALGILIYEMLAGYPPFYDHNRDPMQIYEKICNGKIKFPR--HFDSDANYFKDLIKKLLQVDLTKRYGNMKNGVNDI

FKNPWL
 . .| 
KNHKWF
Kinase 96830.m00065.AA Pkinase_Tyr 336-481 27 6.4e-20 68.08 Pfam 1-158 (270) Show / Hide 
Range on Protein: 336-481
Range on HMM: 1-158/270
Sequence Identity: 27% (44 aa)

FEFIRRISSGAFATVFIAKKK----LTGDIFAIKVIPRTTVIQKNQTSRIMTEKDILKNF-TNPYIVTFYYSIL-GERN--LYLVTEFVPGGDLYSLLQA
 .|.. . .||| .|. .. |     |.   |.|... ..  . |     | |  |.|..  .| || .|  ..  ..   .|.|.|..|.|||.. |..
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRK

----LGSFDEDSSKIYIAEILHALRYLRENGIIHRDLKPDNILVTKNGTLKLTDFGLS
     ....      . ..|  .. || ....|||||   |.|||.|.. | .||||.
HREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLA
Kinase 96830.m00065.AA TyrKc 336-597 21 3.4e-18 67.71 SMART 1-280 (280) Show / Hide 
Range on Protein: 336-597
Range on HMM: 1-280/280
Sequence Identity: 21% (64 aa)

FEFIRRISSGAFATVFIAKKKLTGDIFAIKVIPRTTVIQKNQTSRIMTEKDILKNF--TNPYIVTFYYSILGE-------RNLYLVTEFVPGGDLYSLLQ
 .... . .||| .|. .. |      |.|..   .         .| |  |....   .| || .|  .. .         |..|.|..|.||| . |.
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR

ALGS-FDEDSSKIYIAEILHALRYLRENGIIHRDLKPDNILVTKNGTLKLTDFGLSHQGIVNRQMSNE------PEDIEA----EPEIVGTLDYMAPEIL
. .  .  .    .   |    .|| ....|||||   |.||..|.| | .|||||      |   ..       . . .        .  .  |||| .
KHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLS------RDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI

MNLPHSFGVDYWSLGAMLFEFLT-GVPPFHA-----DTDTETTKNILLNKIDFQPDD-------EMSPEAKDLIKRLLDPNPETRLGVKDINDIF
.    ..  | || | ...| .| | .|         ...|  ...   .   ||..       ....|  ...|.  . .|| |   ..| ..|
NYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF