Gene 81907.m00061 (T.vaginalis)

81907.m00061

Species: T.vaginalis
Alias: 81907.m00061, TvagK0368
External Links:
Annotation:

Classification

Group: AGC
Family: MAST
Subfamily: MAST

Sequence

Name Sequence Type Origin Length Description Download
81907.m00061.AA Protein None 597 None Fasta, JSON
81907.m00061.kin_dom Protein Kinase Domain None 250 None Fasta, JSON

Protein domain

Protein domains of 81907.m00061.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 81907.m00061.AA AGC 208-457 24 2.4e-111 288.62 In-house 1-395 (395) Show / Hide 
Range on Protein: 208-457
Range on HMM: 1-395/395
Sequence Identity: 24% (99 aa)

FEFIKRLSNGAYGRVYLAKKK------TTGEVFAIKAIP-RH--------QMDHQNSAF---------NEKMTLSQVS----------SSSVVS-MYYSI
|||.| .. |..|.|||..||      .||...|.| .  .|        ...| ....         .|.  |....          .  .|. ..|| 
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF

AGVKN--MYIVMEYLP--------GGD---LSRLLD--NVGSFSKDVIRAYAAQ-------IVMALADLRK-FGIIHRD-IKPGNILVNKNGQLKLIDFG
   ..   |.||||.|        ||.   ...| .  . |.|. ...| |||.       ||.||  | .  |||||| .|| ||| ...| .|| |||
QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG

LSYTGSS----------------------------------------------------ERCVKLVG--TPDYLSPEVILNMSHSFSVDYWS--LGAMLY
|.  | .                                                    .|.  ..|  ||.|..||..    .....|.||  ||...|
LCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL----YGKACDWWSFGLGCLMY

EFFEGVPPFHGET----------AEETILNIC--------KGKIPR---------IQCSDALWNLIKGLMDHNSKKMLGAKS-------IEEIMHHPFF
|.  | |||.|..           .|.  .|.        | |.|.          . |. ...|||.|.  . .| ||..        .|||. ||.|
EMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNHPWF
Kinase 81907.m00061.AA S_TKc 208-457 28 9.2e-81 275.54 SMART 1-231 (231) Show / Hide 
Range on Protein: 208-457
Range on HMM: 1-231/231
Sequence Identity: 28% (76 aa)

FEFIKRLSNGAYGRVYLAKKKTTGEVFAIKAIPRHQMDHQNSAFNEKMTLSQVSSSSVVSMYYSIAGVKNMYIVMEYLPG--GDLSRLLDNVGS------
.|... .  ||.|.||....| ||...||| |.       ... .|   |..     .| .|...   ...|.||||..|  ||| ..... |.      
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFP

FSKDVIRAYAAQIVMALADLRKFGIIHRDIKPGNILVNKNGQLKLIDFGLSYTGSSERCVKLVGTPDYLSPEVILNMSHSF-SVDYWSLGAMLYEFFEGV
|.  ..| |..||. ||. . . ||||||.|| |||...  ..|..||||.          ..|||.|..|||.   .... ..| ||.| .|||.. | 
FPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-----TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLCGY

PPFHGETAEETILNICKGKIPRIQCSDALWNLIKGLMDHNSKKMLGAKSIEE----IMHHPFF
|||.    .........        |. ....|..... . .| ..|  . .    |. ||.|
PPFP---QMQMMFKKIG--------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 81907.m00061.AA Pkinase 208-457 27 1.6e-64 225.44 Pfam 1-293 (293) Show / Hide 
Range on Protein: 208-457
Range on HMM: 1-293/293
Sequence Identity: 27% (81 aa)

FEFIKRLSNGAYGRVYLAKKKTTGEVFAIKAIPRHQMDH--QNSAFN--EKMTLSQVSSSSVVSMYYSIAGVKNMYIVMEYLPGG----DLSRLLD--NV
.......  |..|.||....| ||...|.| |...  ..  . ....  |   .  ...  .| .|..    ...|.||||..||    ||....   . 
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

GSF--SKDVIRAYAAQIVMALADLRKFGIIHRDIKPGNILVNKNGQL----KLIDFGLSY---TGSSERCVKLVGTPDYLSPEVIL-NMSHSFSVDYWSL
|.|  | .... |. ||. .|. . . ||||||.|| |||...||..    |..||||.    . ... .  ..|||.|..||||. .  .. .|| ||.
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSC

GAMLYEFFEGVPPFHGE------TAEETILNICKGKIPRIQ---CS-------------------DALWNLIKGLMDHNSKKMLGAKSIEEIMHHPFF
| .|||.. | ||| |.      .  . | .| ......     ||                   ...  .||.. . . || ..   .|.|..||.|
GCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPT---AEQILQHPWF
Kinase 81907.m00061.AA Ciliate-E2-Unclassified 208-457 24 3.3e-63 216.32 In-house 1-352 (352) Show / Hide 
Range on Protein: 208-457
Range on HMM: 1-352/352
Sequence Identity: 24% (85 aa)

FEFIKRLSNGAYGRVYLAKKKTTGEVFAIKAIPRHQMDHQNSA------------FNEKM-------------TLSQVSSSSVVSMYYSIAGVKNMYIVM
...|| . .|..| ||....| .....|.| .  .|...|..              |.|.              |..  .  .| |.|     .|.||||
YKIIKQIGQGGFGKVYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKDEIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIVM

EYLPGGDLSRLLDNVGS-----------------FSKDVIR-----AYAAQIVMALADLRKFG-IIHRDIKPGNILVNKNG---QLKLIDFGLSY-----
||..||||.  . . ..                 |.   ..      |.|||. .|  | . . |||||||| |||...||   ..|.||||.|.     
EYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQN

------------TGSSERCVKLVGTPDYL----SPEVILNMSHS----FSVDYWSLGAMLYEFFEGVPPFHGETAEE---------------TILNICKG
              .....   .||| |.    .|||. .  ..    ...|.||||  |||.  | .|| ... |.                .....| 
NNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNIKQ

KIPRIQC----------SDALWNLIKGLMDHNSKKMLGAK-SIEEIMHHPFF
|.. ...          |.  ...|. |.  . || .. . ..|.|. ||.|
KNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase 81907.m00061.AA AktR 208-457 32 3.4e-61 209.61 In-house 1-268 (268) Show / Hide 
Range on Protein: 208-457
Range on HMM: 1-268/268
Sequence Identity: 32% (88 aa)

FEFIKRLSNGAYGRVYLAKKK-TTGEVFAIKAIPRHQMDHQN---SAFNEKMTLS-QVSSSSVVSMYYSIAGVKNMYIVMEYLPGGDLSRLLDNVGSFSK
|...| | .||.|.|||..|| ......|.| |  . .  .|    . .|.  .  ... .  | ..|...  .. ...||| |||.| . | . . || 
FHVYKCLGKGAFGKVYLVQKKRDNQKQYAMKMIKKKKIIERNQMHHTITERNIMEMCCNHPFIVKLHYCFQTKEKLFFIMEYCPGGELFQHLKKKKKFSE

DVIRAYAAQIVMALADLRKF-GIIHRDIKPGNILVNKNGQLKLIDFGLSY--TG--SSERCVKLVGTPDYLSPEVILN-MSHSFSVDYWSLGAMLYEFFE
...| |.|||. ||  | ..  || ||.|| |||  ..| .|..|||||        .|.  ...||| |..||.|..   | .|||.|..|. .||   
EQARFYFAQILLALEYLHQHMNIIYRDLKPENILLDEDGHVKITDFGLSKLQFMMHYDEKAYSFCGTPEYMAPEMITKKKGHNKSVDWWAFGIFIYEMVT

GVPPFHGETAEETILNICKGK---IPR-IQCSDALWNLIK-GLMDHNSKKMLG--AKSIEEIMHHPFF
| |||  .  .. ...| .     .|  .. |... .||. .|.. | .| ||  ....|||  ||.|
GCPPFYHKNQNQMFQKIKIKQQNKFPYPSYFSSQCKDLIQRKLLCKNPNKRLGYYCNGWEEIKSHPWF
Kinase 81907.m00061.AA Ciliate-E2 208-457 22 4.4e-61 208.42 In-house 1-365 (365) Show / Hide 
Range on Protein: 208-457
Range on HMM: 1-365/365
Sequence Identity: 22% (85 aa)

FEFIKRLSNGAYGRVYLAKKKTTGEVFA--------------------------IKAIPRHQMDHQNSAF----------NEKMTLSQVSSSSVVSMYYS
..||| . .|..| ||..|.. ... ||                          .|     |.   .. .          |||  |.|...  .. ||..
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

IA--GVKNMYIVMEYLPGGDLSRLL-------------------DNVGSFSKDVIR-------AYAAQIVMALADLRKFG-IIHRDIKPGNILVNKNGQL
      .|.|.||||. ||||  ..                     .. ..| ...        |.|.|. ||  | . . |||||||| |||.     .
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----I

KLIDFGLSYTGSSERCVKL---------------------------------VGTPDYLSPEVILNMS---------HSFSVDYWSLGAMLYEFFEGVPP
|.||||||   . ... ..                                 .||| |..||.. . .         .....|.|||| .|||.  | ||
KIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPP

FHGETAEETILNICKGKIP-------------------RIQCSDALWNLIKG----LMDHNSKKMLGAKSIEEIMHHPFF
|        . .|...||                      ..|.   .|||     ... . .| ..  ..|.|. ||.|
F--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRIT--GWEQILNHPWF
Kinase 81907.m00061.AA Ciliate-E2b 208-401 31 5.3e-60 181.07 In-house 1-210 (272) Show / Hide 
Range on Protein: 208-401
Range on HMM: 1-210/272
Sequence Identity: 31% (67 aa)

FEFIKRLSNGAYGRVYLAKK-KTTGEVFAIKAIPRH---QMDHQNSAFNEKMTLSQVSSSSVVSMYYSIAGVKNMYIVMEYLPGGDLSRLLDNVG--SFS
...|| | .|..| ||| .. |.| . .|.|.|.     |     .  .|| .|  .    ..  ..|    ..|| .||.  |..|  .. ..|   .|
MIYIKKLGFGQFGSVYLVWNTKNTKQYYAMKCISKNQIIQQNMEKHMLQEKNVLEKCNHPFIMKFIRSFKDDQHMYFMMEFCNGMELFDVIREIGRLLLS

KDVIRAYAAQIVMALADLRKFGIIHRDIKPGNILVNKNGQLKLIDFGLSYT--GSSE---RCVKLVGTPDYLSPEVIL-----NMSHSFSVDYWSLGAML
. . . | |.|. .|  | . .||.||||| ||.| ..|..||||.|.. .  ...|   |.  ..||| |. ||.|      .   ...|| ||.| .|
TYDSQFYIASICLCLEYLHNQNIIYRDIKPENIMVDHKGYMKLIDMGTAKHMYKKNEQMTRTFTIIGTPHYMAPEIIQSLQPGGKGYTYKVDIWSVGICL

YEFFEGVPPF
|||  | .|.
YEFMCGYVPW
Kinase 81907.m00061.AA RSK-Unclassified 208-457 32 5.1e-58 180.61 In-house 1-283 (283) Show / Hide 
Range on Protein: 208-457
Range on HMM: 1-283/283
Sequence Identity: 32% (91 aa)

FEFIKRLSNGAYGRVYLAKKKTTGEVFAIKAIPRHQMDHQNS---AFNEKMTLSQVSSSSVVSMYYSIAGVKNMYIVMEYLPGGDLSRLLD--NVGSFSK
|. .. .  |  |.||| .|| |  ..|.|   .|.|  .|    .  |.  ..      .| .|.|      .| .||| .|||. | |       |. 
FIKHRLIGQGDFGKVYLVRKKDTQQIYAMKVLHKHKMIRHNKIKYVMTEQNIMATTNHPFIVTLYHSFQTQDYLYLCMEYCMGGDFFRHLQTRKEKCFCE

DVIRAYAAQIVMALADLRKFGIIHRDIKPGNILVNKNGQLKLIDFGLSYTG-----------------------SSERCVKLVGTPDYLSPEVILNMSHS
| .| ||. ...|| .| | ..| || || ||.  . |  .| ||.||  .                        . |    .|| .|| ||.|    | 
DDVRFYASEVTAALEYLHKRDFIYRDLKPDNIVLHQEGHVMLTDFDLSIQAKDSKKPVMKGSAQSTYVDTKICDHGFRTNSFCGTEEYLAPEMIRRCGHT

FSVDYWSLGAMLYEFFEGVPPFHGETAEETILNICKG--KIP-RIQCSDALWNLIKGLMDHNSKKMLGAKSI--EEIMHHPFF
  || | || ..||   |.||. |.  .||  || |.  |.|     |     ||| |.  |  | ||.|.   ..|  ||||
KAVDWWTLGIVMYEMLFGCPPYYGNNKNETFYNIEKNHVKFPHDSYISNNCRDLIKKLLQRNPAKRLGCKMGDADDIKRHPFF
Kinase 81907.m00061.AA RSK 211-457 30 4.8e-57 195.82 In-house 1-278 (278) Show / Hide 
Range on Protein: 211-457
Range on HMM: 1-278/278
Sequence Identity: 30% (84 aa)

IKRLSNGAYGRVYLAKKK---TTGEVFAIKAIPRHQMDHQN----SAFNEKMTLSQVS-SSSVVSMYYSIAGVKNMYIVMEYLPGGDLSRLLDNVGS---
.| |  |.|| |.| .|.    || ..| | . .. ..  .     .. |   |. .  .  .|. .|.    .  |..|||..||.| . | . ..   
LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFGC

FSKDVIRAYAAQIVMALADLRKFGIIHRDIKPGNILVNK---NGQLKLIDFGLSYTGSSE---RCVKLVGTPDYLSPEVIL---NMS-HSFSVDYWSLGA
|| |  ..|.|.||.|.  | . ||||||.|| ||| .    .| .||.|||..  .. .   .  . ..| .|. ||..      . |. ..|.||||.
FSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDESNEGHIKLTDFGFCKQFRCDHNQWTMTFCYTIEYMAPEMLKRANQQGGHDKACDWWSLGV

MLYEFFEGVPPFHG---ETAEETILNICKGK-IPRIQ----CSDALWNLIKGLMDHNSKKMLG--AKSIEEIMHHPFF
 .|| . | |||.|   ....|.. .|.|||  ...      |..  .||....  . .| ||   . .|||  ||.|
LMYEMLTGCPPFQGPNDNNRKEIMKRIQKGKFSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF
Kinase 81907.m00061.AA MAST 208-350 42 1.7e-56 170.78 In-house 1-149 (337) Show / Hide 
Range on Protein: 208-350
Range on HMM: 1-149/337
Sequence Identity: 42% (63 aa)

FEFIKRLSNGAYGRVYLAKKKTTGEVFAIKAIP-RHQMDH--QNSAFNEKMTLSQVSSSSVVSMYYSIAG--VKNMYIVMEYLPGGDLSRLLDNVG-SFS
||||| .|.||||.|||.|.|.|.. ||.| |  . ..|   ....| |. .|....  .||.|.||      |  ..||||. |||   || ..| .. 
FEFIKCISKGAYGAVYLVKHKKTNDRFAMKVINCQDTIDKNQVDQVFVERNILTMYQNPFVVKMFYSFQTPCKKYLCMVMEYMEGGDCASLLRMYGNCMP

KDVIRAYAAQIVMALADLRKFGIIHRDIKPGNILVNKNGQLKLIDFGLS
 .  . | |..| .|  | . ||.|||.|| |.|  .|| .|| |||||
EWMAKMYIAETVLCLEYLHSYGIVHRDLKPDNMLIDSNGHIKLTDFGLS
Kinase 81907.m00061.AA MAST 208-350 42 7.3e-55 175.14 In-house 1-146 (334) Show / Hide 
Range on Protein: 208-350
Range on HMM: 1-146/334
Sequence Identity: 42% (62 aa)

FEFIKRLSNGAYGRVYLAKKKTTGEVFAIKAIPRHQMDHQ---NSAFNEKMTLSQVSSSSVVSMYYSIAGVKNMYIVMEYLPGGDLSRLLDNVGSFSKDV
||||| .|.||||.|||.|.|.|.. ||.| |   .|      .. . |. .|.....  ||.|.||    .. ..||||. |||.  || ..|.|  . 
FEFIKPISKGAYGKVYLVKHKKTNDRFAMKVIKKSDMINKNMVDQVQVERNILAMYQNPFVVKMFYSFQTKNYLCMVMEYMEGGDCASLLHMYGYFDEWM

IRAYAAQIVMALADLRKFGIIHRDIKPGNILVNKNGQLKLIDFGLS
 . | |..|..|  | . ||.|||.|| |.|  .||  || |||||
AKMYIAETVLCLEYLHSHGIVHRDLKPDNMLIDSNGHIKLTDFGLS
Kinase 81907.m00061.AA NDR 208-350 38 2.6e-44 134.19 In-house 1-151 (350) Show / Hide 
Range on Protein: 208-350
Range on HMM: 1-151/350
Sequence Identity: 38% (60 aa)

FEFIKRLSNGAYGRVYLAKKKTTGEVFAIKA------IPRHQMDHQNSAFNEKMTLSQVS--SSSVVSMYYSIAGVKNMYIVMEYLPGGDLSR---LLDN
||.|| .. ||.|.|.|..|| ||...|.|       . ..|..|     .|.  .....  .  ||..|||    .. | ||||.||||.     || .
FEIIKIIGKGAFGEVWLVRKKDTGHIYAMKIMRKSEMMWKNQVAH---VRAERDIMAEADNKNPWVVKLYYSFQDKQYLYLVMEYHPGGDMMTYCYLLMK

VGSFSKDVIRAYAAQIVMALADLRKFGIIHRDIKPGNILVNKNGQLKLIDFGLS
 . |. |..| | | .|.|. .. | |.||||||| |.|..| | .||.||||.
MDIFTEDWARFYIAEMVCAIESVHKMGYIHRDIKPDNFLIDKDGHIKLTDFGLC
Kinase 81907.m00061.AA NDR 360-457 34 1.9e-36 109.47 In-house 240-350 (350) Show / Hide 
Range on Protein: 360-457
Range on HMM: 240-350/350
Sequence Identity: 34% (38 aa)

KLVGTPDYLSPEVILN-MSHSFSVDYWSLGAMLYEFFEGVPPFHGETAEETILNICKGKIPR------IQ----CSDALWNLIKGLMDHNSKKMLGAKS-
..||||||. |||...   .....|.||||...||.  |.|||...| .||  .| . |.        ..     |.  |.||. |.  . .. ||..  
STVGTPDYMAPEVFQQKTGYNQTCDWWSLGCIMYEMLVGYPPFCSDTPQETCMKIMNWKQTWDWPMTHFPPEANLSPEAWDLIRRLCCPDPDHRLGSHGK

-IEEIMHHPFF
 ..||  ||||
GVDEIKSHPFF
Kinase 81907.m00061.AA MAST 360-457 41 3.2e-35 104.58 In-house 227-337 (337) Show / Hide 
Range on Protein: 360-457
Range on HMM: 227-337/337
Sequence Identity: 41% (46 aa)

KLVGTPDYLSPEVILNMS-HSFSVDYWSLGAMLYEFFEGVPPFHGETAEE-TILNICK--GKIPRIQC---------SDALWNLIKGLMDHNSKKMLGAK
. .|||||..|||||  . .. .||.||.| ..|||  |.||| |.| || .  || .   .|  .           |.    ||| | ..| || |||.
QCCGTPDYIAPEVILGQGTYGKPVDWWSMGIIMYEFLVGCPPFNGDTPEEMIFQNIINHDREIEWPEEGDPNDDDCMSPEAQDLIKKLLQPNPKKRLGAN

SIEEIMHHPFF
  .||. ||||
GADEIKQHPFF
Kinase 81907.m00061.AA MAST 360-457 37 9.3e-32 99.4 In-house 223-334 (334) Show / Hide 
Range on Protein: 360-457
Range on HMM: 223-334/334
Sequence Identity: 37% (42 aa)

KLVGTPDYLSPEVILNMS-HSFSVDYWSLGAMLYEFFEGVPPFHGETAEETILNICKGK-----IPRI-------QCSDALWNLIKGLMDHNSKKMLGAK
...|||||..|||||. . |. .||.||.| ..|||. |.||| ..| ||.  || . .     .|           |     ||. | ... .| |||.
QCCGTPDYIAPEVILGQGTHGKPVDWWSMGIIMYEFLVGCPPFNDDTPEEIFQNILNRNCNEIEWPEGGDINDDEAMSPEAQDLIEKLLQPDPRKRLGAN

-SIEEIMHHPFF
   .|.. ||||
NGADEVKQHPFF
Kinase 81907.m00061.AA TyrKc 208-452 21 3e-14 7.69 SMART 1-280 (280) Show / Hide 
Range on Protein: 208-452
Range on HMM: 1-280/280
Sequence Identity: 21% (62 aa)

FEFIKRLSNGAYGRVYLAKKKTTGEVFAIKAIPRHQMDHQNSAFNEKMTLSQV--SSSSVVSMYYSIAGV-------KNMYIVMEYLPGGDLSRLL-DNV
 ...| | .||.|.||... |   .  |.| .  .    .    .|   ....  .   .| .|  .          . ..||||| |.|||   | .. 
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA---REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHR

GSFSKDVIRAYAAQIVMALADLRKFGIIHRDIKPGNILVNKNGQLKLIDFGLSYTGSSE-RC-----VKLV----GTPD-----YLSPEVILNMSHSFSV
. .. .    .. ||    . | . ..||||.   |.||..|.. |  |||||  . .. ..     .. .    |. .      ..||.|     ..  
PKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTTKS

DYWSLGAMLYEFFE-GVPPFHG-----ETAEETILNICKG---KIPRI-------QCSDALWNLIKGLMDHNSKKMLGAKSIEEIM
| || | ...| |  | .|  |      ...| | .. .|   ..|          |.|.. ...|   ... ..    . | |..
DVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase 81907.m00061.AA S_TK_X 458-511 20 1.5e-07 32.31 SMART 1-79 (79) Show / Hide 
Range on Protein: 458-511
Range on HMM: 1-79/79
Sequence Identity: 20% (16 aa)

KGIDWKHVH----KIVPPFIPALK----NDFDTSYFD----PNPEVGDSAQNNIAIGS--------------IVKIDDMS
.||||...     .| |||.| .|    ...|||.||     .. . .. .. ....|                  . . 
RGIDWDKLYNQQKEIEPPFKPKIKEVYASPTDTSNFDPEFTEETPM-LTPDDPPLSNSMWQNEMETEIPPDPFRGFTYVF
Kinase 81907.m00061.AA Pkinase_Tyr 208-350 28 6.8e-07 23.98 Pfam 1-158 (270) Show / Hide 
Range on Protein: 208-350
Range on HMM: 1-158/270
Sequence Identity: 28% (46 aa)

FEFIKRLSNGAYGRVYLAKKK-----TTGEVFAIKAIPRHQMDHQN---SAF-NEKMTLSQV-SSSSVVSMYYSIA-GVKN--MYIVMEYLPGGDLSRLL
 .|.| |  ||.|.||... |     |. .| |.| . ... .|..    .| .|  ...|  .   .|..|  .    .   .|||||| |.|||   |
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPV-AVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYL

DN----VGSFSKDVIRAYAAQIVMALADLRKFGIIHRDIKPGNILVNKNGQLKLIDFGLS
 .     ....   .  ...|| .... |   ..||||.   |.||..|.. |  ||||.
RKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLA
Kinase 81907.m00061.AA APH 315-353 22 0.000676 14.17 Pfam 162-205 (248) Show / Hide 
Range on Protein: 315-353
Range on HMM: 162-205/248
Sequence Identity: 22% (10 aa)

ALADLRK-FGIIHRDIKPGNILVN--KNGQLK--LIDFGLSYTG
.|....  ....|.| .|||....   .|.    .||.. .  |
WLEAHWPPPCWCHGDFHPGNVMWDPRPDGGRVTGVIDWDDACWG
Kinase 81907.m00061.AA Pkinase_Tyr 368-416 30 1.087786 2.96 Pfam 181-232 (270) Show / Hide 
Range on Protein: 368-416
Range on HMM: 181-232/270
Sequence Identity: 30% (16 aa)

LSPEVILNMSHSFSVDYWSLGAMLYEFFE-GVPP-FHGETAEETILNI-CKG
..||.| ..  .   | || |  ..| |  |  | . | . || .  |  .|
MAPECINYGKFTTKSDVWSFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDG