Gene 95946.m00100 (T.vaginalis)

95946.m00100

Species: T.vaginalis
Alias: 95946.m00100, TvagK0344
External Links:
Annotation:

Classification

Group: TKL
Family: TKL-Tvag1

Sequence

Name Sequence Type Origin Length Description Download
95946.m00100.AA Protein None 848 None Fasta, JSON
95946.m00100.kin_dom Protein Kinase Domain None 252 None Fasta, JSON

Protein domain

Protein domains of 95946.m00100.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 95946.m00100.AA TKL 31-276 24 9.2e-76 258.01 In-house 1-364 (364) Show / Hide 
Range on Protein: 31-276
Range on HMM: 1-364/364
Sequence Identity: 24% (92 aa)

IGKGGFGEVKRAVEKK--------TGRECAVKTIFTERLEGNKL-------------------------RRYLGEVKTMSQCHNMFLVPFVGFTAEPP--
||.|||||| ... .         ||.. |||.. ..    . .                          .   |.. ||...   .|.|.|.  .||  
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

------------YAIITEYMSNGS-LDRFVRNRSGMSLSGTQLTAIAIGIANGMIHLHKIG--------IIHRDLKAANIMLDSRLF-------------
            ..|..||...|| |...            |.  .|..|| || .||  .        ||||||| .||..|. .              
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH---------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADW

-PRIGDFGIARFGETDGGMTA--------------------KIGTPNYMAPELITSH----------------DYNEKVDVYSYGMILYEMTQNVRPFKN
 . |.|||..|| ...|.|..                    ..|||..||||..  .                .|.||.||||.|..|.|.    ||...
CCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPYYD

MKME---------EIFDLVLKKDRRPTFY------------LDLPDSLKALIEACWATNPNDRPSFEEIYNAF
....         |.| .| .| .||.               | |.|.| |.. ||...|..||||.||   .
YPYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
Kinase 95946.m00100.AA TKL-Unique 27-276 28 1.6e-65 224.03 In-house 1-290 (290) Show / Hide 
Range on Protein: 27-276
Range on HMM: 1-290/290
Sequence Identity: 28% (84 aa)

FGDTIGKGGFGEVKRAVEKKTGRECAVKTIFT-ERLEGNKLRRYLGEVKTMSQCH-NMFLVPFVGFTA----EPP-YAIITEYMSNGSLDRFVR------
|. .|| ||.|.|.... ...  . |.|...  | ..  ...    ||..|.  |   ..| ..|...     || . |..||.. |||.          
FWNKIGEGGYGQVYKGKWRGY--PVAIKQFHPNEDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNNNN

--NRSGMSLSGTQLTAIAIGIANGMIHLHKIG--IIHRDLKAANIMLDSR-----LFPRIGDFGIARFGETDGGMTAK----------IGTPNYMAPELI
  |.. . |.  |   .|| || ||..||  .  |||||||  |. .|..     .  .| |||...|  ..  ||..          .|....||||..
NNNNNNCKLNMQQRVKMAIDIAQGMYYLHHCEPPIIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFRWMAPEVL

TS--HDYNEKVDVYSYGMILYEMTQNVR------PFKNMKMEEIFDLVLK--KDRRPTFYLDLPDSLKALIEACWATNPNDRPSFEEIYNAF
..   .|.||.||||.|..|.|.  . .      |...|  |... .| .  .  ||.   ..| ... ||..||. .| .||||.||..  
RMNFCQYSEKSDVYSFGIVLWEIATRKITKTYKKPYQGMDQEQWCEMVHYMEENYRPPIPNHCPKEYRDLIQQCWHHDPSQRPSFDEIIHRL
S_TKc 95946.m00100.AA S_TKc 25-277 27 3.5e-65 223.76 SMART 1-231 (231) Show / Hide 
Range on Protein: 25-277
Range on HMM: 1-231/231
Sequence Identity: 27% (74 aa)

FEFGDTIGKGGFGEVKRAVEKKTGRECAVKTIFTERLEGNKLRRYLGEVKTMSQCHNMFLVPFVGFTAEPPYAIITEYMSN--GSLDRFVRNRSG----M
.|....||||.||.|.....|||||..|.| |          .. . |.. ... |  ..| . ..  .  . ...||...  |.| .. ..| .     
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQDDHLYMVMEYCDGDLGDLFDYIKKRGRHGLRF

SLSGTQLTAIAIGIANGMIHLHKIGIIHRDLKAANIMLDSRLFPRIGDFGIARFGETDGGMTAKIGTPNYMAPELITSHDYNE-KVDVYSYGMILYEMTQ
 ..  .   ..  |.... ..|. |||||||| .||.||.     |.|||.||.       |  .|||.|||||..    |.  |.|..| | |||||  
PFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLC

NVRPFKNMKMEEIFDLVLKKDRRPTFYLDLPDSLKALIEACWATNPNDRPSFEEIYN--------AFV
   ||    |...|....            ....| .|. |.  .|..||.  |. .         ..
GYPPFP--QMQMMFKKIG------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Pkinase 95946.m00100.AA Pkinase 25-276 25 2e-62 218.5 Pfam 1-293 (293) Show / Hide 
Range on Protein: 25-276
Range on HMM: 1-293/293
Sequence Identity: 25% (75 aa)

FEFGDTIGKGGFGEVKRAVEKKTGRECAVKTIFTERLEGNKLRRYLG--EVKTMSQCHNMFLVPFVGFTA-EPPYAIITEYMSNG----SLDRFVRNRSG
...| .||.|.||.|.....|.||.. |||.|  .. . .|... .   |.. |  ..  . | . ..   .. . ...||. .|    .| .... ...
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

MSL--SGTQLTAIAIGIANGMIHLHKIGIIHRDLKAANIMLDSRLFP----RIGDFGIARF--GETDGGMTAKIGTPNYMAPELIT-SHDYNEKVDVYSY
 ..  |  ..  ..  |. |. ..|. |||||||| .||..|..  .    .|.|||.|..     .. ||   |||.|||||.|  . .|  |||..|.
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSC

GMILYEMTQNVRPFKNM------KMEEIFDLVLKKDRRPTFYLDLP-------------------DSLKALIEACWATNPNDRPSFEEIYNA--F
| |||||     ||..        . .......... .  .. . .                   ...| .|. |.. .|..||..|.| .   |
GCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase 95946.m00100.AA MLK 25-276 26 2.2e-56 193.62 In-house 1-291 (291) Show / Hide 
Range on Protein: 25-276
Range on HMM: 1-291/291
Sequence Identity: 26% (78 aa)

FEFGDTIGKGGFGEVKRAVEKKTG---RECAVKTIF-------TERLEGNKLRRYLGEVKTMSQCH-NMFLVPFVGFTAEP-P-YAIITEYMSNGSLDRF
..|   ||.|.||.| ... ...    .. ||| ..        .  |  ....   ... .|.   .   ..|.|  ..| . ..|..||...||| ..
IQFHEWIGSGSFGKVWKGRWRNKDIVAKIVAVKRVRARIFDKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQPPCHFCIVMEYCEGGSLYNV

VRN-RSGMS-----------LSGTQLTAIAIGIANGMIHLHKIG---IIHRDLKAANIMLDS------RLFPRIGDFGIAR-FGETDGG-MTAKIGTPNY
 .. ||. .            .  ..  .|  .|.||  ||.     |||||||  ||..|        .  .| |||..| . ...   |. ..||. .
LHGARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHSMAPKPIIHRDLKSHNILIDEICHDMHHGTLKICDFGTSRDWHQMC-TNMMSNAGTYAW

MAPELI---TSHDYNEKVDVYSYGMILYEMTQNVRPFK-NMK-MEEIFDLVLKKDRRPTFYLDLPDSLKALIEACWATNPNDRPSFEEIYNAF
|||| |    .  |.||.||.|.|..|.||     |.|  .. |. ..  ....  ||.   . |...| |.. || ..|..|||| .|   .
MAPEVIQQFRCEKYSEKCDVWSWGVVLWEMLTREVPYKQHYDPMAIAWWVAYNG-LRPPIPSTCPEHWKKLMKQCWNQDPHKRPSFRQIVQHL
Kinase 95946.m00100.AA Pkinase_Tyr 25-276 29 7.4e-56 189.79 Pfam 1-270 (270) Show / Hide 
Range on Protein: 25-276
Range on HMM: 1-270/270
Sequence Identity: 29% (79 aa)

FEFGDTIGKGGFGEVKRAVEK----KTGRECAVKTIFTERLEGNK--LRRYLGEVKTMSQC-HNMFLVPFVGFTA--EPP--YAIITEYMSNGSLDRFVR
 .|| ..|.| ||||.... |    .|. ..|||..  |        ..  . |.|.|.|  |.  .| ..|     . |  . |..||| .|.|. . |
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR

NR--SGMSLSGTQLTAIAIGIANGMIHLHKIGIIHRDLKAANIMLDSRLFPRIGDFGIARFGETDGGM-TAKIGTP---NYMAPELITSHDYNEKVDVYS
..  .. .|.  .|  ... ||.|| .|. ...||||| | |..... .. .|.||| ||  . |.   ... |..     |||| |    ...| ||.|
KHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECINYGKFTTKSDVWS

YGMILYEMTQNV-RP-FKNMKMEEIFDLVLKKDRRPTFYLDLPDSLKALIEACWATNPNDRPSFEEIYNAF
.|  ..|.      | ...|. ||..... .. .|     . || .  |.  ||. .|.|||.|.||.. .
FGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYRMPCPENCPDEIYDLMKQCWHYDPEDRPTFSEIHEQL
Kinase 95946.m00100.AA Dicty5 98-280 37 1.4e-52 179.34 In-house 76-260 (260) Show / Hide 
Range on Protein: 98-280
Range on HMM: 76-260/260
Sequence Identity: 37% (70 aa)

IITEYMSNGSLDRFVRNRSG---MSLSGTQLTAIAIGIANGMIHLHKIGIIHRDLKAANIMLDSRLFPRIGDFGIARFGETDGGMTAKIGTPNYMAPELI
..||| .||||    . .       ..  |   .||.||..| ||| ..|||||||  |. .  ..   | |||. || .   .||  .||...||.|| 
HVTEYCHNGSLFNYLNDQRKTTGQPIAYFQQLHMAIDIAQSMRHLHSMNIIHRDLKSMNFLITENWKIKIIDFGTSRFVDNRYHMTMHVGTQCWMACELF

TSHDYNEKVDVYSYGMILYEMTQNVRPFKNMKMEEIFDLVLKKDRRPTFYLDLPDSLKALIEACWATNPNDRPSFEEIYNAFVRGE
..  | .|.||||.| .|.||     |..|.   .|  .| | . |||   | | .   ||..||   |  |||| ||   | .  
NGQPYHQKCDVYSFGIVLWEMFTRKEPYDNINNWNIPVMVMKGE-RPTIPKDCPTEISNLIKKCWQQKPHNRPSFKEICKYFESII
Kinase 95946.m00100.AA TyrKc 25-276 26 7.3e-52 179.54 SMART 1-280 (280) Show / Hide 
Range on Protein: 25-276
Range on HMM: 1-280/280
Sequence Identity: 26% (78 aa)

FEFGDTIGKGGFGEVKRAVEKKTGRECAVKTIFTERLEGNKLRRYLGEVKTMSQC--HNMFLVPFVGFTAE--------PPYAIITEYMSNGSLDRFVRN
 ..|...| | |||| ... |   ...|||..  .      ..  . | . |..   |.  .| ..|   .        .|. |..|||..|.|. . |.
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRK

RSGMSLSGTQLTAIAIGIANGMIHLHKIGIIHRDLKAANIMLDSRLFPRIGDFGIARFGETD------GGMTAK---IGTP-----NYMAPELITSHDYN
. .  |.  .|  ... ||.|| .||. ..||||| | |.......  .|.||| .|... |      . .  |    |.        |||| |  . ..
HRPK-LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFT

EKVDVYSYGMILYEM-TQNVRPFKN-----MKMEEIFDLVLKKDRRPTFYLD-------LPDSLKALIEACWATNPNDRPSFEEIYNAF
.| ||.|.|  ..|. |    |  .     |. .|.. .| . .|.|    |        || .  ... ||. .|.|||.|.||.  |
TKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase 95946.m00100.AA Dicty4 98-278 33 8.2e-50 164.4 In-house 79-277 (277) Show / Hide 
Range on Protein: 98-278
Range on HMM: 79-277/277
Sequence Identity: 33% (66 aa)

IITEYMSNGSLDRFVRN-----RSGMSLSGTQLTA---IAIGIANGMIHLHK-I-GIIHRDLKAANIMLDSRLFPRIGDFGIAR---FGETDGG-MTAKI
| ||||. |.| .  ..      .  .|. .  ..   .|. .| ||..||  .  |||||||..|.. |  .   ..|||...    .|. .  ... .
IVTEYMPKGNLYSLLHDKPSEQQQSIKLDWPLIKRAMRMAFDAARGMNWLHCCNPVIIHRDLKSHNLLVDKNWRVKVCDFGLSQYMKKHEDHKDNQMTAC

GTPNYMAPELITSHDYNEKVDVYSYGMILYEMTQNVRPFK--NMKMEEIFDLVLKKDRRPTFYLDLPDSLKALIEACWATNPNDRPSFEEIYNA--FVR
||| .||||   .. ||||.||||.|..|.|.     |.    |  ......|  |  ||    . |.|.|.||. || ..|. ||||||| ..     
GTPCWMAPEVMMHQPYNEKADVYSFGIVLWEILTRQEPYQKHHMPYMQFVRAVCNKKLRPPIPDWCPPSWKHLIQWCWDHDPQHRPSFEEIIQRRILEH
Kinase 95946.m00100.AA LRRK 95-272 31 8.3e-50 171.79 In-house 129-345 (351) Show / Hide 
Range on Protein: 95-272
Range on HMM: 129-345/351
Sequence Identity: 31% (69 aa)

PYAIITEYMSNGSLDRFVRNRSGMSL-----S---GTQLTAIAIGIANGMIHLHKIG--IIHRDLKAANIML---D---------SRLFPRIGDFGIAR-
|.....||...|.|..| .|.. ...     .   ...|  ||. || || .||.    |||||||  || |   .               |.|||| | 
PLCMVMEYAPHGDLYHFLHNKKQDGFHFMKAHISWMLKLK-IALQIAKGMEYLHSHNPPIIHRDLKSPNILLWSSPQNHSPNYPNAHVCAKIADFGISRM

FGETDGG--MTAKIGTPNYMAPELITSH---DYNEKVDVYSYGMILYE-MTQNVRPFKN------MKMEEIFDLVLKKDRRPTFYLD-LPD-----SLKA
|  ...      . |.| .|||| .       |.||||.||.||||.| .|  ..|| .      |...|.. .  .. .|||.  .  |      ....
F-QCFHMGVAKGCVGNPGWMAPEIMRYNGEEEYTEKVDCYSFGMILWELLTRQHHPFDEHDFFDHMQWMEQIEDKIIEGLRPTIPQHYCPPCQPWHMYQD

LIEACWATNPNDRPSFEEI
||. ||...|..||.|..|
LIQHCWQHDPKKRPHFSQI
Kinase 95946.m00100.AA TK 25-276 14 2.2e-49 163.3 In-house 1-486 (486) Show / Hide 
Range on Protein: 25-276
Range on HMM: 1-486/486
Sequence Identity: 14% (69 aa)

FEFGDTIGKGGFG---EVKRA-------------------------VEKKTGRECAVKTIFTERLEGNKLRRY---------------LGEVKTMSQ--C
 ..|...|.| ||   || ..                          ....  ..|||..  .  .  . ..                . | | |..  .
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

HNMFLVPFVG-FTAE------------PPYAIITEYMSNGS----LDRFVRNRSG---------------------------------------------
|   .| ..|  | .            .|. |..|||..|.    |. . |....                                             
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

---------MSLSGTQLTA-------------------IAIGIANGMIHLHKI------GIIHRDLKAANIMLDSRLF-----------PRIGDFGIA--
         ..|. ..|                     ..  ||.|| .||.       ...|||| | |.......             .|.||| .  
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLLMCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSRQ

------RFGETDGGMTAKIGTPN---------------------------YMAPELITSHD---------YNEKVDVYSYGMILYEMTQNV-RPFKN-MK
      |  . |.  ..| .                              .|||| ....          . .| ||.|.|  ..|.  .   |.   | 
GSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGMS

M---------EEIFDLVLK-------------KDRRPTFYLDLP--------------DSLKALIEACWATNPNDRPSFEEIYNAF
          .|..... .                |.    . |              . .  |.  ||. .|.|||.|.......
NQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL
Kinase 95946.m00100.AA STE 25-277 21 3.9e-49 169.56 In-house 1-359 (359) Show / Hide 
Range on Protein: 25-277
Range on HMM: 1-359/359
Sequence Identity: 21% (80 aa)

FEFGDTIGKGGFGEVKRAVEKK---------------TGRECAVKTIFTERLE---------------GNKLRRYLGEVKTMSQCH--NMFLVPFVGFTA
.|. . ||||.||.| .|. .|               ||. .|.| .  |. .                ... ..| |.|.|..|.    . | . |   
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

--------EPPYAIITEYMSNGSLDRFVRN--RSGMSLS----------GTQLTAIAIGIANG-MIHLHKIGIIHRDLKAANIMLDSRLFPRIGDFGIAR
        .    |. |||..|||| ....    |..|.           .|. .|.  |  | . .||. .|||||.|.|||.|       . |||.. 
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-----VKLCDFGVCG

FGETDGG----------------MT-AKIGTPNYMAPELITS------HDYNEKVDVYSYGMILYEMTQNVRPFKNMK-MEEIFDLVLKK----------
  . ..                 ..   .||| .|||| |.       ..|..|.|..| |  . ||     |. .|. |. .|    ..          
QLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQLC

---DRRPTFYLDLP-------------------DSLKALIEACWATNPNDRPSFEEIYN---AFV
   .  |..  .|                    ...|  |. |   .||.||. ..  .    |.
IVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI
Kinase 95946.m00100.AA Dicty4-Unclassified 25-276 30 8.5e-46 154.81 In-house 1-263 (263) Show / Hide 
Range on Protein: 25-276
Range on HMM: 1-263/263
Sequence Identity: 30% (82 aa)

FEFGDTIGKGGFGEVKRAVEKKTGRECAVKTIFTERLEGNK---LRRYLGEVKTMSQCHNMFLVPFVGFTAEP-----PYAIITEYMSNGSLDRFVR---
      |||| | .| . . |  |.. ||| .| |         .  .. ||  .       ||   |    |      . |..| |  | |   .    
IQIDQFIGKGHFSKVHKGNWK--GKDVAVK-KFNENKFKFREEMIQDFKKEVEILGSIQHPNLVKCYGYCINPRSHKSTMCIVMEFMHKGNLFEVIHSKP

--NRSGMSLSGTQLTAIAIGIANGMIHLHKIGIIHRDLKAANIMLDSRLFPRIGDFGIARFGETDGGMTAKIGTPNYMAPELITSHDYNEKVDVYSYGMI
      ..|  |   ..|. || || |||   .||||.|..||..|     .|.||||.|  .    ||.  |||   .||      || | |||||.|.
SEQQQPIKLDDTLIIKYAFDIAQGMQHLHTRNFIHRDIKSSNILMDKHFNIKIADFGISRVIDFNFNMTTIAGTPKWESPECLMHESYNQKSDVYSYAMM

LYEMTQNVRPFKNMK-MEEIFDLVLKKDRRPTFYLDLPDSLKALIEACWATNPNDRPSFEEIYNAF
|||.     |.       ..  .|  |  ||      .  .| ||  ||   || ||....| .  
LYELATGDEPYQEIQSIMNAARSVCDKKLRPKIPDNCDNFWKKLIKWCWHNDPNKRPTMNQIIQYL
Kinase 95946.m00100.AA RIPK 31-276 27 1.3e-44 149.94 In-house 1-290 (290) Show / Hide 
Range on Protein: 31-276
Range on HMM: 1-290/290
Sequence Identity: 27% (80 aa)

IGKGGFGEVKRAVEKKTGRECAVKT----IFTERLEGNKLRRYLGEVKTMSQCHNMFLVPFVGFTAEP------P-YAIITEYMSNGSLDRFVRNRSG--
.|.|||||| .|. .. | . |.|        . ..  .    . |.| | .  . . ||  ||. ..        |.| .||| ||||  |   ..   
VGGGGFGEVFKARHRHWGDWVAKKCKPCKHCHTHMDDQERMYQKEEAKHMHKLRCEHIVPIYGFCQCEEWDCDCKLYGIVMEYMENGSLWHFLHTKWPYQ

---MSLSGTQLTA-IAIGIANGMIHLHKIG--IIHRDLKAANIMLDSRLFPRIGDFGIARFGETD--GG----------MTAKI--GTPNYMAPELIT--
     ..   |.  .   |. ||  || ..  ||||||| .|| .|. .   | ||| | . ..   ..          |. |   ||  ||.||..   
HHPDPWP---LRCRMIHEISCGMCYLHSMNPPIIHRDLKPENILVDNNFHVKIADFGLATWMMWSHSHQDRCNQREVYSMKSKNRWGTLSYMPPEHFRTD

SHDY----NEKVDVYSYGMILYEMTQNVRPFKNMKMEEIFDLVLKKDRRP-----TFYLDLP---DSLKALIEACWATNPNDRPSFEEIYNAF
  .     ..| ||||......|   .  |. . | .... ...|.. ||     . | . |    ... |.. ||. .|||||.| |.   .
NKKPIKVVTPKYDVYSFAIVMWEVLTQKHPYEDRKCMMMIMMCCKQGHRPCLQPVPEYWPEPPHCEQMIELMQRCWQQDPNDRPCFQECEEWT
Kinase 95946.m00100.AA Dicty4 25-39 53 0.015215 4.5 In-house 1-15 (277) Show / Hide 
Range on Protein: 25-39
Range on HMM: 1-15/277
Sequence Identity: 53% (8 aa)

FEFGDTIGKGGFGEV
  ... ||||.||||
INIEQRIGKGSFGEV
Kinase 95946.m00100.AA LRRK 25-39 43 0.023242 4.14 In-house 1-16 (351) Show / Hide 
Range on Protein: 25-39
Range on HMM: 1-16/351
Sequence Identity: 43% (7 aa)

FEFGDTIGKGGFG-EV
....  ||.|||| .|
LKIEEQIGRGGFGTFV