Gene 87835.m00244 (T.vaginalis)

87835.m00244

Species: T.vaginalis
Alias: 87835.m00244, TvagK0395
External Links:
Annotation:

Classification

Group: AGC
Family: Akt

Sequence

Name Sequence Type Origin Length Description Download
87835.m00244.AA Protein None 423 None Fasta, JSON
87835.m00244.kin_dom Protein Kinase Domain None 252 None Fasta, JSON

Protein domain

Protein domains of 87835.m00244.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
PH 87835.m00244.AA PH 4-99 18 8.4e-13 49.77 SMART 1-82 (82) Show / Hide 
Range on Protein: 4-99
Range on HMM: 1-82/82
Sequence Identity: 18% (18 aa)

VLINGFLNKKGSKFGFWHKRYVVAIGSQIIISKSQTDKPERYINMNGDVTIESQSDVSPPRFTLTPKGEKPITLATNTVEELNDWLNQMRSMTFMT
|.. |.| ||.  .  |.||..|  ...... |.   ||   |....  |..         |...  ..  ....... ||...|.. .....   
VIKEGWLYKKS--K-RWKKRWFVLFNDCLYYYKDK--KPKGSIPLSDC-TVRE-P-----CFEIHH-DR-TYYFQCESEEEMQEWMQAIQKAIHNN
PH 87835.m00244.AA PH 4-97 24 1.4e-09 37.25 Pfam 1-92 (92) Show / Hide 
Range on Protein: 4-97
Range on HMM: 1-92/92
Sequence Identity: 24% (23 aa)

VLINGFLNKKGSKFGFWHKRYVVAIGSQIIISKSQTDKPERYINMNGDVTIESQSDV-SPPRFTLTPKGEKPITLATNTVEELNDWLNQMRSMTF
| . |.| ||| |.. |.||..|  ...... |. . .| ..|....  ...  .|   |  | ..  ... ....... ||.|||.. ..|   
VIKEGWLHKKG-KRKSWKKRWFVLFNNCLYYYKDDKYRPKGSIPLSDC-QVTKVPDNKRPHCFQIRT-DRRTYYFQAESEEEMNDWMQAIQSACR
Kinase 87835.m00244.AA AGC 107-358 31 8.4e-163 424.77 In-house 1-395 (395) Show / Hide 
Range on Protein: 107-358
Range on HMM: 1-395/395
Sequence Identity: 31% (125 aa)

FDVISVLGRGFYGKVMLCHKK------NTNDIFAIKTVHKNR-LVSAK--KVHTIFTE------------RNVLMKAQ----------HPFIVS-LKFAF
|... |.|.| .|||.|. ||       |....|.| . | .  |  |  .|. . ||            ||.|.|..          |||||. |...|
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF

QTDTK--VYLGLEYAP---------GG-ELFYHLQ---KFGSFPIDDVRIYIAE-------MALALDFLHK-HGVIYRD-IKPENILLDAQGHVKLTDFG
|....  .|. .||.|         || |||.|||   | |.|. . .|.|.||       ..|||..||. .|.|.|| .||||||||..||.||||||
QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG

LAKDLTDES---------------------------------------------------STTTFCG--TFEYMAPEVVARSSYGPAIDWWA--LGILTY
|.| . ..                                                     |.||||  | ||||||..    ||.| |||.  ||.| |
LCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL----YGKACDWWSFGLGCLMY

ELLNGHSPFQSDN----------RALLFMSIR------TQPPKFP----------ARTDRNTIDFISNLLNKDPELRYG----------MDQIRTHPFF
|.| |..||..||          .. .| .|.      ....|||             . .  |.|. ||.|||| | |           ..|. ||.|
EMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNHPWF
Kinase 87835.m00244.AA Akt 107-358 44 7.2e-123 394.62 In-house 1-264 (264) Show / Hide 
Range on Protein: 107-358
Range on HMM: 1-264/264
Sequence Identity: 44% (118 aa)

FDVISVLGRGFYGKVMLCHKKNTNDIF-AIKTVHKNRLVSAKKVHTIFTERNVLMKAQHPFIVSLKFAFQTDTKVYLGLEYAPGGELFYHLQKFGSFPID
||.. |||.| .|||.|. ||.|.... |.|   |....  ..|  ..||||.| . .|||||.|...||| .| |. ..|..|||||||||. . |. |
FDFLKVLGKGSFGKVFLVKKKDTQKWYYAMKVLKKDYIIQKNQVEHTKTERNILQHCNHPFIVNLHYSFQTQDKLYFVMDYCNGGELFYHLQRKRRFSED

DVRIYIAEMALALDFLHKHGVIYRD-IKPENILLDAQGHVKLTDFGLAK-D-LTDESSTTTFCGTFEYMAPEVVARSSYGPAIDWWA-LGILTYELLNGH
  | |.||. ||...||....||||  ||||||.|..||..||||||.| . ..|   |.||||| ||.|||.     .. | |||. ||...||.. | 
RARFYCAEIILAIEHLHSKNIIYRDYLKPENILMDKDGHICLTDFGLCKENIIKDHDKTKTFCGTPEYLAPEILNGNGHTKAVDWWGSLGCVMYEMMCGR

SPFQSDNRALLFMSIRTQPPKFP--ARTDRNTIDFISNLLNKDPELRYG-----MDQIRTHPFF
 || ....  .|  | .|| |||   . . .  |.|| ||||||..| |      ..|. ||.|
PPFYNQDHHQMFKKIKNQPVKFPDKDWISPECKDLISGLLNKDPKKRLGGGPNDAQEIKRHPWF
Kinase 87835.m00244.AA SGK 107-358 39 5.8e-121 375.43 In-house 1-283 (283) Show / Hide 
Range on Protein: 107-358
Range on HMM: 1-283/283
Sequence Identity: 39% (113 aa)

FDVISVLGRGFYGKVMLCHKKNT------------------NDIFAIKTVHKNRLV-------SAKKVHTIFTER-NVLMKAQHPFIVSLKFAFQTDTKV
|| ..|.| | .|||..  .| .                   ...|.|   |.  .         |..  | .|| ..| .  |||||.|..||||..| 
FDFLKVIGKGSFGKVYQVKHKDDETCQRVWLIFQSLLSQSEDKFYAMKVLQKQHIINEYRQDLKKKEQKHIMAERNVILKNMKHPFIVNLHYAFQTKWKL

YLGLEYAPGGELFYHLQKFGSFPIDDVRIYIAEMALALDFLHKHGVIYRDIKPENILLDAQGHVKLTDFGLAK-DLTDESSTTTFCGTFEYMAPEVVARS
|. ..|. |||.|||||. ..|| | .|.| || ..||. ||.  .|||| ||||||||.|||..||||||.| .  ..  |.||||| ||.|||| .  
YFVMDYVNGGEMFYHLQREKHFPEDRARFYAAEIVCALEYLHSQDIIYRDLKPENILLDHQGHCCLTDFGLCKEGIKTNDTTFTFCGTPEYLAPEVLRKQ

SYGPAIDWWALGILTYELLNGHSPFQSDNRALLFMSIRTQPPKFPARTDRNTIDFISNLLNKDPELRYGMD----QIRTHPFF
 .. . ||| ||.. ||.. |  || | |.....  |. || ..|        | |  ||.|||. | |      .|. ||||
PHDRTVDWWCLGCVLYEMMYGLPPFYSRNKQQMYDNIINQPLQIPPQMSNDAWDLIQGLLQKDPKKRLGTKRDFMEIKNHPFF
Kinase 87835.m00244.AA RSK 110-358 42 4.4e-112 378.67 In-house 1-278 (278) Show / Hide 
Range on Protein: 110-358
Range on HMM: 1-278/278
Sequence Identity: 42% (118 aa)

ISVLGRGFYGKVMLCHKK---NTNDIFAIKTVHKNRLVSAKK-VHTIFTERNVLMKAQ-HPFIVSLKFAFQTDTKVYLGLEYAPGGELFYHLQKFGS---
..|||.| |||| ||.|.   .|. |.| | ..|. .| ..| . . .||||.|.  | |||||.|. ||||..|.|| .|| .|||||.|||| ..   
LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFGC

FPIDDVRIYIAEMALALDFLHKHGVIYRDIKPENILLDA---QGHVKLTDFGLAKD-LTD-ESSTTTFCGTFEYMAPEVVA----RSSYGPAIDWWALGI
|  |....|.|| .||...||..|.|.||.||||||.|    .||.||||||..|    | .. | |||.| ||||||...    .. .. | ||| ||.
FSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDESNEGHIKLTDFGFCKQFRCDHNQWTMTFCYTIEYMAPEMLKRANQQGGHDKACDWWSLGV

LTYELLNGHSPFQS---DNRALLFMSIRTQP--PKFP--ARTDRNTIDFISNLLNKDPELRYG-----MDQIRTHPFF
| ||.| |..|||.   .||. ..  |..    ...|  .   ..  |.|. .| .||. |.|     ...|. ||.|
LMYEMLTGCPPFQGPNDNNRKEIMKRIQKGKFSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF
Kinase 87835.m00244.AA AktR 107-358 40 1.5e-108 366.95 In-house 1-268 (268) Show / Hide 
Range on Protein: 107-358
Range on HMM: 1-268/268
Sequence Identity: 40% (109 aa)

FDVISVLGRGFYGKVMLCHKK-NTNDIFAIKTVHKNRLVSAKKVHTIFTERNVLM-KAQHPFIVSLKFAFQTDTKVYLGLEYAPGGELFYHLQKFGSFPI
|.|. .||.| .|||.|. || ......|.| ..|  ..  .. | . ||||..  ...||||| |...|||..| .. .|| ||||||.||.| . |  
FHVYKCLGKGAFGKVYLVQKKRDNQKQYAMKMIKKKKIIERNQMHHTITERNIMEMCCNHPFIVKLHYCFQTKEKLFFIMEYCPGGELFQHLKKKKKFSE

DDVRIYIAEMALALDFLHKH-GVIYRDIKPENILLDAQGHVKLTDFGLAK---DLTDESSTTTFCGTFEYMAPEVVAR-SSYGPAIDWWALGILTYELLN
...|.|.|.. |||..||.|  .||||.||||||||  ||||.|||||.|   .  ..  ...||||.||||||.. .   .. ..||||.||. ||.. 
EQARFYFAQILLALEYLHQHMNIIYRDLKPENILLDEDGHVKITDFGLSKLQFMMHYDEKAYSFCGTPEYMAPEMITKKKGHNKSVDWWAFGIFIYEMVT

GHSPFQSDNRALLFMSIRTQP---PKFPARTDRNTIDFIS-NLLNKDPELRYG-----MDQIRTHPFF
|. ||...|.  .| .|....   ...|.    .  |.|   ||.|.|. | |      ..|. ||.|
GCPPFYHKNQNQMFQKIKIKQQNKFPYPSYFSSQCKDLIQRKLLCKNPNKRLGYYCNGWEEIKSHPWF
Kinase 87835.m00244.AA PKA 107-358 41 2.8e-104 352.73 In-house 1-263 (263) Show / Hide 
Range on Protein: 107-358
Range on HMM: 1-263/263
Sequence Identity: 41% (109 aa)

FDVISVLGRGFYGKVMLCHKKNTNDIFAIKTVHKNRLVSAKKVHTIFTERNVLMKAQHPFIV-SLKFAFQTDTKVYLGLEYAPGGELFYHLQKFGSFPID
|. | .||.| .|.|||| .|.. ...|.|.  |.. |  | |. . .|.|.|.  .||||| .... ||.|.. |. .||.||||.|..|.| |.|. .
FEIIQTLGTGSFGRVMLCRHKHSGNYYAMKMLKKQEIVRLKQVEHVHNEKNILQNIKHPFIVKKMYWTFQDDRYLYMVMEYVPGGEMFSYLRKSGRFSNP

DVRIYIA-EMALALDFLHKHGVIYRDIKPENILLDAQGHVKLTDFGLAKDLTDESSTTTFCGTFEYMAPEVVARS-SYGPAIDWWALGILTYELLNGHSP
. ..|.| .  |||..||..  |||| ||||||.| .||.|.|||| || ..|   | | |||.||.|||.. ..  .| ..|||||||| ||.| |..|
HAKFYAASQIVLALEYLHSQNIIYRDLKPENILIDKNGHIKITDFGFAKKVDD--RTWTLCGTPEYLAPEIIQSKNGHGKSVDWWALGILIYEMLAGYPP

FQSD--NRALLFMSIRTQPPKFPARTDRNT---IDFISNLLNKDPELRY-----GMDQIRTHPFF
|  .  . . ..  |.    |||   | .     |.|..||..|.. ||     | ..|..|..|
FYDHNRDPMQIYEKICNGKIKFPRHFDSDANYFKDLIKKLLQVDLTKRYGNMKNGVNDIKNHKWF
Kinase 87835.m00244.AA S_TKc 107-358 36 2.9e-104 353.59 SMART 1-231 (231) Show / Hide 
Range on Protein: 107-358
Range on HMM: 1-231/231
Sequence Identity: 36% (98 aa)

FDVISVLGRGFYGKVMLCHKKNTNDIFAIKTVHKNRLVSAKKVHTIFTERNVLMKAQHPFIVSLKFAFQTDTKVYLGLEYAPG--GELFYHLQKFGS---
.... ..|.| .|||..|..|.|. |.||| ..           .|  |...|.| .||.|| |. .||. ...|. .||..|  |.|| ...| |.   
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

---FPIDDVRIYIAEMALALDFLHKHGVIYRDIKPENILLDAQGHVKLTDFGLAKDLTDESSTTTFCGTFEYMAPEVVARSSYGP-AIDWWALGILTYEL
   ||  ..| |......||...|.||.|.||.||||||||   |.|..|||||. |      |||||| .||||||.   .||. ..|||..|.. ||.
RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEM

LNGHSPFQSDNRALLFMSIRTQPPKFPARTDRNTIDFISNLLNKDPELRYGMDQIRT-------HPFF
| |  ||.  . ...|  |.          ..  .|||...|.|||| |..  .. .       ||.|
LCGYPPFP--QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 87835.m00244.AA RSK-Unclassified 107-358 39 1.8e-103 325.94 In-house 1-283 (283) Show / Hide 
Range on Protein: 107-358
Range on HMM: 1-283/283
Sequence Identity: 39% (111 aa)

FDVISVLGRGFYGKVMLCHKKNTNDIFAIKTVHKNRLVSAKKVHTIFTERNVLMKAQHPFIVSLKFAFQTDTKVYLGLEYAPGGELFYHLQ--KFGSFPI
| ..  .|.|  ||| |  ||.|. |.|.|  ||....  .|.  . ||.|..   .||||| | ..|||  . || .|| .||..| |||  |   |  
FIKHRLIGQGDFGKVYLVRKKDTQQIYAMKVLHKHKMIRHNKIKYVMTEQNIMATTNHPFIVTLYHSFQTQDYLYLCMEYCMGGDFFRHLQTRKEKCFCE

DDVRIYIAEMALALDFLHKHGVIYRDIKPENILLDAQGHVKLTDFGLAKDL----------------------TDESSTTTFCGTFEYMAPEVVARSSYG
||||.|..|  .||  ||| ..|||| ||.||.|.  |||.||||.| ..                        . . |  |||| ||.|||.. |   .
DDVRFYASEVTAALEYLHKRDFIYRDLKPDNIVLHQEGHVMLTDFDLSIQAKDSKKPVMKGSAQSTYVDTKICDHGFRTNSFCGTEEYLAPEMIRRCGHT

PAIDWWALGILTYELLNGHSPFQSDNRALLFMSIRTQPPKFP--ARTDRNTIDFISNLLNKDPELRYG-----MDQIRTHPFF
 |.||| |||. ||.| |  |.  .|.  .|  | ... |||      .|  | |  ||.. |  | |      | |. ||||
KAVDWWTLGIVMYEMLFGCPPYYGNNKNETFYNIEKNHVKFPHDSYISNNCRDLIKKLLQRNPAKRLGCKMGDADDIKRHPFF
Kinase 87835.m00244.AA PKC 107-358 39 7.4e-99 321.07 In-house 1-262 (262) Show / Hide 
Range on Protein: 107-358
Range on HMM: 1-262/262
Sequence Identity: 39% (104 aa)

FDVISVLGRGFYGKVMLCHKKNTNDIFAIKTVHKNRLVSAKKVHTIFTERNVLMKA-QHPFIVSLKFAFQTDTKVYLGLEYAPGGELFYHLQKFGSFPID
|. . |||.| .|||||  .|.|. ..||| . |   .    |    ||. ||  | .||| ..|   |||  . .  .||  || | .| |... |.  
FNFLKVLGKGSFGKVMLAERKGTDEYYAIKVLKKDVIIQDDDVECTMTEKRVLALAWKHPFLTHLHCCFQTMDRLFFVMEYVNGGDLMFHIQQQRRFKEE

DVRIYIAEMALALDFLHKHGVIYRDIKPENILLDAQGHVKLTDFGLAKD-LTDESSTTTFCGTFEYMAPEVVARSSYGPAIDWWALGILTYELLNGHSPF
  | | || ..|| |||..|.|||| | .|.|||. ||.|..|||..|. ..... |.||||| .|.|||...   ||...||||.|.| ||.. |.|||
HARFYAAEIICALQFLHEKGIIYRDLKLDNVLLDHEGHIKIADFGMCKENMWNGDTTSTFCGTPDYIAPEILQYQEYGKSVDWWAFGVLMYEMMAGQSPF

QSDNRALLFMSIRTQPPKFPARTDRNTIDFISNLLNKDPELRYGM--------DQIRTHPFF
  ..   || ||... | .|    .   . .. ...|.|| | |.        . ||.||||
HGEDEDELFQSIMHDNPHYPRWLSKEAVSICKGFMTKNPEKRLGCHPQQEEGEQDIREHPFF
Kinase 87835.m00244.AA p70 107-358 39 7.4e-96 324.76 In-house 1-299 (299) Show / Hide 
Range on Protein: 107-358
Range on HMM: 1-299/299
Sequence Identity: 39% (117 aa)

FDVISVLGRGFYGKVMLCHKKN---TNDIFAIKTVHKNRLVSAKK--VHTI------------------------FTERNVLMKAQHPFIVSLKFAFQTD
|  . |||.| ||||..  | .   |. |.| |   |   |   |   ||                         | |||.|   .||||. | .||||.
FELLKVLGKGGYGKVFQVRKVTGEDTGKIYAMKVLRKAKIVRNQKDTAHTREDEDKNDGNNNDNDDGLSKRLERTFAERNILEEVKHPFICDLHYAFQTN

TKVYLGLEYAPGGELFYHLQKFGSFPIDDVRIYIAEMALALDFLHKHGVIYRDIKPENILLDAQGHVKLTDFGLAKDLTDESST-----------TTFCG
 | || ||| .|||||.|| . | .. | .. | .|  .|| .||.||.|||| ||||..|..||||.|||||| |    ...             ||||
GKLYLILEYLHGGELFMHLERHGIWMEDTACFYLSEIICALEHLHQHGIIYRDLKPENCMLNQQGHVVLTDFGLCKESIHDGAVDEEDPENVNATHTFCG

TFEYMAPEVVARSSYGPAIDWWALGILTYELLNGHSPFQSDNRALLFMSIRTQP--PKFPARTDRNTIDFISNLLNKDPELRYG-----MDQIRTHPFF
| ||||||.. |. .. |.|||.||.| |  | |  ||  .||.    .|      .| |.       | |  || ..| .| |       .|. ||||
TIEYMAPEILMRCGHNHAVDWWSLGCLMYDMLTGGPPFTGENRKKTIDKILKGKQGLKLPPYLTHEMRDLIKKLLKRHPTQRWGAGPEDAADIQEHPFF
Kinase 87835.m00244.AA Pkinase 107-358 31 1e-91 315.82 Pfam 1-293 (293) Show / Hide 
Range on Protein: 107-358
Range on HMM: 1-293/293
Sequence Identity: 31% (94 aa)

FDVISVLGRGFYGKVMLCHKKNTNDIFAIKTVHKNRLVSAKKVHTIF-TERNVLMKAQHPFIVSLKFAFQTDTKVYLGLEYAPGG----ELFYHLQ--KF
. .....|.| .|.| .||.|.|..|.|.|.. | .  | |... .  .|  .. . .||.|| |. .|......|. .||..||    .|| ...  . 
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

GSF--PIDDVRIYIAEMALALDFLHKHGVIYRDIKPENILLDAQGHV----KLTDFGLAKD--LTDESSTTTFCGTFEYMAPEVVA-RSSYGPAIDWWAL
|.|  . .... |. ... .|...|..|.|.||.||||||.| .||.    |..||||||   .   | .|||||| .||||||.  .. |||..|.|..
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSC

GILTYELLNGHSPFQSD------NRALLFMSIRTQPPKFPARTD---------------------RNTIDFISNLLNKDPELRYGMDQIRTHPFF
|.. ||.|.|. ||...      .   ..  |.  |..|.  ..                     .. .|||...|.|||. |.. .||  ||.|
GCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase 87835.m00244.AA RSK 107-358 36 1.2e-87 297.54 In-house 1-271 (271) Show / Hide 
Range on Protein: 107-358
Range on HMM: 1-271/271
Sequence Identity: 36% (99 aa)

FDVISVLGRGFYGKVMLCHKK---NTNDIFAIKTVHKNRLVSAKKVHTIFTERNVLMKAQHPFIVSLKFAFQTDTKVYLGLEYAPGGELFYHLQKFGSFP
.......|.| ..|| .|.|.    ||. .|.| . |. .. . .     .||..|   .||||| |. .||. .|||. .. . ||.|| .|.| ..|.
YELHECIGQGSFSKVYVCKKCQHKDTNQHYAMKIIKKATRDVKDR-VCWEEERIILRYGHHPFIVKLHYVFQDEGKVYMIMDFMRGGDLFDRLLKQKMFS

IDDVRIYIAEMALALDFLHKHGVIYRDIKPENILLDAQ----GHVKLTDFGLAKDLTDESS-TTTFCGTFEYMAPEVVARSSYGPAIDWWALGILTYELL
 ..|..| || |||...||..|...|| ||||||.|..    ||.|..|||.|| | ||   . |||.| .||||||. |  .. | ||| .|.| || |
EREVKFYMAEIALAMEYLHSQGIVHRDLKPENILYDDESGNPGHIKICDFGFAKQLRDENGMLMTFCYTANYMAPEVLKRQGHDQACDWWSFGVLMYEML

NGHSPFQSDNRALLFMSIRTQPPKF-------PARTDRNTIDFISNLLNKDPELRYGM-----DQIRTHPFF
 |. |||. .|  ..  |  ..          ..   .   | .. .|  ||. |.|       ||. ||.|
TGCTPFQNKPRDTPMNIIQRIKLGMFSMTHGNWDFISDEAKDLLRMMLHRDPHNRLGAGPNGVEQIKQHPWF
Kinase 87835.m00244.AA TyrKc 107-358 20 1.2e-15 30.2 SMART 1-280 (280) Show / Hide 
Range on Protein: 107-358
Range on HMM: 1-280/280
Sequence Identity: 20% (59 aa)

FDVISVLGRGFYGKVMLCHKKNTNDIFAIKTVHKNRLVSAKKVHTIFTERNVLMKA--QHPFIVSLKFAFQTD-------TKVYLGLEYAPGGELFYHLQ
   . .||.|..|.|.... |      |.|.....       .  .  | ....|   .|| || |  .  ..         ... .||.|.| |  .|.
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR

KFGS-FPIDDVRIYIAEMALALDFLHKHGVIYRDIKPENILLDAQGHVKLTDFGLAKDLTDE------SSTTTF----CGT----FEYMAPEVVARSSYG
| .  .. .|   .    |   ..||....| ||.   |.|......|| .||||..|..|.      ... .     .|        ||||.   . . 
KHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFT

PAIDWWALGILTYELL-NGHSPFQS------DNRALLFMSIRTQPPKFPAR--------TDRNTIDFISNLLNKDPELRYGMDQIRTHPFF
.. | |. |.. .|.. .| .|         .|. ..    .   .. |.               . ..   . ||| |  . .|  | .|
TKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF
Kinase 87835.m00244.AA Pkinase_Tyr 107-305 24 1.2e-11 40.1 Pfam 1-217 (270) Show / Hide 
Range on Protein: 107-305
Range on HMM: 1-217/270
Sequence Identity: 24% (53 aa)

FDVISVLGRGFYGKVMLCHKK----NTNDIFAIKTVHKNRLVSAK-KVHTIFTERNVLMKA-QHPFIVSLKFAFQ-TDTK--VYLGLEYAPGGELFYHLQ
   . .||.| .|.|.... |    ||.   |.|.. |.   .   .    . | .....  .|| ||.|  .    .    .|. .||.|.| |  .|.
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR

K----FGSFPIDDVRIYIAEMALALDFLHKHGVIYRDIKPENILLDAQGHVKLTDFGLAKDLTDESST-TTFCGTFE---YMAPEVVARSSYGPAIDWWA
|     ..... |   . .. | ....|. .. | ||.   |.|.. ...|| .|||||.|.....   ..  |.      ||||. . . .  . | |.
KHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECINYGKFTTKSDVWS

LGILTYELLN-GHSP-FQ
 |.| .|..  | .| ..
FGVLMWEIFTYGEQPTYP
Kinase 87835.m00244.AA S_TK_X 359-418 24 8.1e-10 39.86 SMART 1-79 (79) Show / Hide 
Range on Protein: 359-418
Range on HMM: 1-79/79
Sequence Identity: 24% (20 aa)

NGMNFDDVLE--KKYKPSFVPTIP----NDVAALNFDSEFTCEPAQDSIATPVGQ------GNE----------FNGFSFVA
 | ..|...   |...| |.|.|     ..  . ||| ||| |..    .||. .      ...          | ||..|.
RGIDWDKLYNQQKEIEPPFKPKIKEVYASPTDTSNFDPEFTEETPM---LTPDDPPLSNSMWQNEMETEIPPDPFRGFTYVF
Kinase 87835.m00244.AA Pkinase_C 387-420 39 3.3e-07 28.66 Pfam 10-46 (46) Show / Hide 
Range on Protein: 387-420
Range on HMM: 10-46/46
Sequence Identity: 39% (15 aa)

NFDSEFTCEPAQDS----IATPVGQGNEFNGFSFVAPG
||| |||.||..|.       . |. ..| ||..|.| 
NFDPEFTDEPPMDTPPDWR-MSSGDQEPFRGFTYVNPD