Gene 90981.m00083 (T.vaginalis)

90981.m00083

Species: T.vaginalis
Alias: 90981.m00083, TvagK0411
External Links:
Annotation:

Classification

Group: AGC
Family: Akt

Sequence

Name Sequence Type Origin Length Description Download
90981.m00083.AA Protein None 440 None Fasta, JSON
90981.m00083.kin_dom Protein Kinase Domain None 258 None Fasta, JSON

Protein domain

Protein domains of 90981.m00083.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
PH 90981.m00083.AA PH 6-101 34 4.3e-23 83.97 SMART 1-82 (82) Show / Hide 
Range on Protein: 6-101
Range on HMM: 1-82/82
Sequence Identity: 34% (33 aa)

QIHSGWCTKIGYYIKSWKKRWFVLTSHTLTYFIEPNGKERGIIDLLQIKEIRPFPECAKPNAFMITVPERTYEISCENAKQMEEWVNLITKARDEL
 |..|| .| .    .||||||||....|.|. ..  | .|.|.|  . ..|. |      .| |.  .|||...||....|.||.. | || ...
VIKEGWLYKKS--K-RWKKRWFVLFNDCLYYYKDK--KPKGSIPLSDC-TVRE-P------CFEIHH-DRTYYFQCESEEEMQEWMQAIQKAIHNN
PH 90981.m00083.AA PH 6-99 33 8.3e-19 70.47 Pfam 1-92 (92) Show / Hide 
Range on Protein: 6-99
Range on HMM: 1-92/92
Sequence Identity: 33% (32 aa)

QIHSGWCTKIGYYIKSWKKRWFVLTSHTLTYFIEPNGKERGIIDLLQIKEIRPFPECAKPNAFMITVPER-TYEISCENAKQMEEWVNLITKARD
 |..|| .| | ..||||||||||.. .| |. ... . .|.|.|  . .... |.  .|. | |.  .| ||....|....|..|.. | .|  
VIKEGWLHKKG-KRKSWKKRWFVLFNNCLYYYKDDKYRPKGSIPLSDC-QVTKVPDNKRPHCFQIRT-DRRTYYFQAESEEEMNDWMQAIQSACR
Kinase 90981.m00083.AA AGC 117-374 34 8.20000000001e-179 467.12 In-house 1-395 (395) Show / Hide 
Range on Protein: 117-374
Range on HMM: 1-395/395
Sequence Identity: 34% (137 aa)

FDILKVLGKGSYGKVQLVRHK------MTDLIYAMKSISKQL---LSEHDLVSRIIAE------------RDVLLSIN----------HPFLVS-ARYAF
|..|||.||||.||| |||.|       |. .|||| ..|.    . ... | ....|            |..|  .|          |||.|.   |.|
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF

QTETK--IFLVLDYVQ---------GG-ELFSRLR---AEQKFAEPRARYYIAE-------LVSAIGYLHK-KGIMHRD-LKPENILFDKDGYIKLTDFG
|....  ...|..|..         || |||..|.    |..| |.|||.|.||       .|.|. |||. .|| ||| |||||||.|.||.|||||||
QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG

LVKRNMTKD--------------------------------------------------STTTTFCG--TPEYLAPEMINGNEYTISVDWWA--IGTLAY
| |..|...                                                   .|.||||  ||||.|||..    |. ..|||.   | | |
LCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL----YGKACDWWSFGLGCLMY

EMLYGVPPFYDAN----------TNAMYRSIL------RDEVVFP----------EDASLDAIDLITKLLDKDPKTRLGSGPTD-----AEEIKAHPFF
|||.| ||||. |           . |. .|.       ..| ||          .  | .| |||.||| |||. |||.|. |     |||||.||.|
EMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNHPWF
Kinase 90981.m00083.AA Akt 117-374 52 3.1e-156 502.97 In-house 1-264 (264) Show / Hide 
Range on Protein: 117-374
Range on HMM: 1-264/264
Sequence Identity: 52% (139 aa)

FDILKVLGKGSYGKVQLVRHKMTDLIY-AMKSISKQLLSEHDLVSRIIAERDVLLSINHPFLVSARYAFQTETKIFLVLDYVQGGELFSRLRAEQKFAEP
||.||||||||.||| ||. | |. .| |||...|. . ... |  ...|| .|  .||||.|.  |.|||..|...|.||..|||||. |. ...| |.
FDFLKVLGKGSFGKVFLVKKKDTQKWYYAMKVLKKDYIIQKNQVEHTKTERNILQHCNHPFIVNLHYSFQTQDKLYFVMDYCNGGELFYHLQRKRRFSED

RARYYIAELVSAIGYLHKKGIMHRD-LKPENILFDKDGYIKLTDFGLVKRN-MTKDSTTTTFCGTPEYLAPEMINGNEYTISVDWWA-IGTLAYEMLYGV
|||.|.||...||..||.|.|. || ||||||| ||||.|.|||||| |.| .. . .|.||||||||||||..||| .| .||||. .| . |||..| 
RARFYCAEIILAIEHLHSKNIIYRDYLKPENILMDKDGHICLTDFGLCKENIIKDHDKTKTFCGTPEYLAPEILNGNGHTKAVDWWGSLGCVMYEMMCGR

PPFYDANTNAMYRSILRDEVVFP--EDASLDAIDLITKLLDKDPKTRLGSGPTDAEEIKAHPFF
||||. .   |.  |.  .| ||  .  | .. |||..|| |||| |||.|| ||.|||.||.|
PPFYNQDHHQMFKKIKNQPVKFPDKDWISPECKDLISGLLNKDPKKRLGGGPNDAQEIKRHPWF
Kinase 90981.m00083.AA SGK 117-374 47 1e-151 472.13 In-house 1-283 (283) Show / Hide 
Range on Protein: 117-374
Range on HMM: 1-283/283
Sequence Identity: 47% (135 aa)

FDILKVLGKGSYGKVQLVRHKMT------------------DLIYAMKSISKQLLS-------EHDLVSRIIAER-DVLLSINHPFLVSARYAFQTETKI
||.|||.||||.||| .|.|| .                  | .|||| ..||             ..  | ||| ..|  ..|||.|. .|||||..| 
FDFLKVIGKGSFGKVYQVKHKDDETCQRVWLIFQSLLSQSEDKFYAMKVLQKQHIINEYRQDLKKKEQKHIMAERNVILKNMKHPFIVNLHYAFQTKWKL

FLVLDYVQGGELFSRLRAEQKFAEPRARYYIAELVSAIGYLHKKGIMHRDLKPENILFDKDGYIKLTDFGLVKRNMTKDSTTTTFCGTPEYLAPEMINGN
..|.|||.|||.|. |. |..| |.||| | ||.|.|..|||.. | .||||||||| | .|...|||||| | .. .  ||.||||||||||||.... 
YFVMDYVNGGEMFYHLQREKHFPEDRARFYAAEIVCALEYLHSQDIIYRDLKPENILLDHQGHCCLTDFGLCKEGIKTNDTTFTFCGTPEYLAPEVLRKQ

EYTISVDWWAIGTLAYEMLYGVPPFYDANTNAMYRSILRDEVVFPEDASLDAIDLITKLLDKDPKTRLGSGPTDAEEIKAHPFF
..  .|||| .|.. |||.|| ||||. |.. ||  |.. .  .|   | || |||. || |||| |||.   |..||| ||||
PHDRTVDWWCLGCVLYEMMYGLPPFYSRNKQQMYDNIINQPLQIPPQMSNDAWDLIQGLLQKDPKKRLGTK-RDFMEIKNHPFF
Kinase 90981.m00083.AA AktR 117-374 46 2.7e-124 419.23 In-house 1-268 (268) Show / Hide 
Range on Protein: 117-374
Range on HMM: 1-268/268
Sequence Identity: 46% (124 aa)

FDILKVLGKGSYGKVQLVRHK-MTDLIYAMKSISKQLLSEHDLVSRIIAERDVLL-SINHPFLVSARYAFQTETKIFLVLDYVQGGELFSRLRAEQKFAE
|...|.|||| .||| ||..|  .. .||||.|.|. . |  . ...| ||...   .||||.|   |.|||..|.|....|..|||||. |. ..|| |
FHVYKCLGKGAFGKVYLVQKKRDNQKQYAMKMIKKKKIIERNQMHHTITERNIMEMCCNHPFIVKLHYCFQTKEKLFFIMEYCPGGELFQHLKKKKKFSE

PRARYYIAELVSAIGYLHKK-GIMHRDLKPENILFDKDGYIKLTDFGLVK-RNMT-KDSTTTTFCGTPEYLAPEMING-NEYTISVDWWAIGTLAYEMLY
 .|| |.|. . |. |||..  |. ||||||||| |.||..|.||||| |  .|  .| ....|||||||.|||||.    .. ||||||.|.. |||..
EQARFYFAQILLALEYLHQHMNIIYRDLKPENILLDEDGHVKITDFGLSKLQFMMHYDEKAYSFCGTPEYMAPEMITKKKGHNKSVDWWAFGIFIYEMVT

GVPPFYDANTNAMYRSILRDE-VVFPEDASL--DAIDLIT-KLLDKDPKTRLGSGPTDAEEIKAHPFF
| ||||. |.| |. .|.  . . ||. . .   . |||. |||.|.|. |||..  ..|||| ||.|
GCPPFYHKNQNQMFQKIKIKQQNKFPYPSYFSSQCKDLIQRKLLCKNPNKRLGYYCNGWEEIKSHPWF
Kinase 90981.m00083.AA PKA 117-374 44 6.4e-119 401.37 In-house 1-263 (263) Show / Hide 
Range on Protein: 117-374
Range on HMM: 1-263/263
Sequence Identity: 44% (119 aa)

FDILKVLGKGSYGKVQLVRHKMTDLIYAMKSISKQLLSEHDLVSRIIAERDVLLSINHPFLV-SARYAFQTETKIFLVLDYVQGGELFSRLRAEQKFAEP
|.|...||.||.|.|.|.||| .  .|||| ..||       | ... |. .|..|.|||.| .  . ||.......|..||.|||.||.||....| .|
FEIIQTLGTGSFGRVMLCRHKHSGNYYAMKMLKKQEIVRLKQVEHVHNEKNILQNIKHPFIVKKMYWTFQDDRYLYMVMEYVPGGEMFSYLRKSGRFSNP

RARYYIA-ELVSAIGYLHKKGIMHRDLKPENILFDKDGYIKLTDFGLVKRNMTKDSTTTTFCGTPEYLAPEMINGN-EYTISVDWWAIGTLAYEMLYGVP
 |. |.| . |.|. |||.. |..||||||||| ||.|.||.|||| .|.  ..|  | | ||||||||||.|..   .  |||||| | | |||| |.|
HAKFYAASQIVLALEYLHSQNIIYRDLKPENILIDKNGHIKITDFGFAKK--VDD-RTWTLCGTPEYLAPEIIQSKNGHGKSVDWWALGILIYEMLAGYP

PFYDA--NTNAMYRSILRDEVVFPEDASLDA---IDLITKLLDKDPKTRLGSGPTDAEEIKAHPFF
||||   .....|. |.  .. ||.  . ||    ||| ||| .|.. |.|.   ... || |..|
PFYDHNRDPMQIYEKICNGKIKFPRHFDSDANYFKDLIKKLLQVDLTKRYGNMKNGVNDIKNHKWF
Kinase 90981.m00083.AA RSK 120-374 44 4.90000000001e-116 391.8 In-house 1-278 (278) Show / Hide 
Range on Protein: 120-374
Range on HMM: 1-278/278
Sequence Identity: 44% (124 aa)

LKVLGKGSYGKVQLVRHK---MTDLIYAMKSISKQLLSEHDL-VSRIIAERDVLLSIN-HPFLVSARYAFQTETKIFLVLDYVQGGELFSRLRAEQK---
|||||.|.|||| |.| .    |. ||||| ..|  .  ..  . .  .||..|. .. |||.|.  ||||||.|..|...|. ||||| .|. |.    
LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFGC

FAEPRARYYIAELVSAIGYLHKKGIMHRDLKPENILFDK---DGYIKLTDFGLVKR-NMTKDSTTTTFCGTPEYLAPEMIN----GNEYTISVDWWAIGT
| | .|..|.||.|.|. .||..|| ||||||||||.|    .| |||||||. |  .  . . | |||.| ||.||||..    .. .. ..|||  | 
FSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDESNEGHIKLTDFGFCKQFRCDHNQWTMTFCYTIEYMAPEMLKRANQQGGHDKACDWWSLGV

LAYEMLYGVPPFYD---ANTNAMYRSILRDE--VVFP--EDASLDAIDLITKLLDKDPKTRLGSGPTDAEEIKAHPFF
| |||| | |||.    .| .   . |.. .  . .|  .  | .| |||.|.| .||. |||.|| ||||||.||.|
LMYEMLTGCPPFQGPNDNNRKEIMKRIQKGKFSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF
Kinase 90981.m00083.AA PKC 117-374 43 3.2e-111 361.8 In-house 1-262 (262) Show / Hide 
Range on Protein: 117-374
Range on HMM: 1-262/262
Sequence Identity: 43% (114 aa)

FDILKVLGKGSYGKVQLVRHKMTDLIYAMKSISKQLLSEHDLVSRIIAERDVL-LSINHPFLVSARYAFQTETKIFLVLDYVQGGELFSRLRAEQKFAEP
|. ||||||||.||| |...| || .||.| . | .  . | |    .|. || |. .||||..    |||. ..| |. ||.|| |       ..| |.
FNFLKVLGKGSFGKVMLAERKGTDEYYAIKVLKKDVIIQDDDVECTMTEKRVLALAWKHPFLTHLHCCFQTMDRLFFVMEYVNGGDLMFHIQQQRRFKEE

RARYYIAELVSAIGYLHKKGIMHRDLKPENILFDKDGYIKLTDFGLVKRNMTKDSTTTTFCGTPEYLAPEMINGNEYTISVDWWAIGTLAYEMLYGVPPF
.|| | || ..|  .||.|||  |||| .|.| |..| ||..|||. | ||....||.||||||.|.||| . . ||. |||||| | | |||. | .||
HARFYAAEIICALQFLHEKGIIYRDLKLDNVLLDHEGHIKIADFGMCKENMWNGDTTSTFCGTPDYIAPEILQYQEYGKSVDWWAFGVLMYEMMAGQSPF

YDANTNAMYRSILRDEVVFPEDASLDAIDLITKLLDKDPKTRLGSGPTD---AEEIKAHPFF
   .   . .||. |....| . | .| ........|.|..|||..|..   ...|..||||
HGEDEDELFQSIMHDNPHYPRWLSKEAVSICKGFMTKNPEKRLGCHPQQEEGEQDIREHPFF
Kinase 90981.m00083.AA RSK-Unclassified 117-374 38 6.6e-111 349.71 In-house 1-283 (283) Show / Hide 
Range on Protein: 117-374
Range on HMM: 1-283/283
Sequence Identity: 38% (109 aa)

FDILKVLGKGSYGKVQLVRHKMTDLIYAMKSISKQLLSEHDLVSRIIAERDVLLSINHPFLVSARYAFQTETKIFLVLDYVQGGELFSRLR--AEQKFAE
|   . .|.|. ||| ||| | |. |||||  .|. .  | .. ... |....   |||| |   ..|||. . .|...|  ||..|  |    | .|.|
FIKHRLIGQGDFGKVYLVRKKDTQQIYAMKVLHKHKMIRHNKIKYVMTEQNIMATTNHPFIVTLYHSFQTQDYLYLCMEYCMGGDFFRHLQTRKEKCFCE

PRARYYIAELVSAIGYLHKKGIMHRDLKPENILFDKDGYIKLTDFGLVKRN--------------------MTKDST-TTTFCGTPEYLAPEMINGNEYT
 ..|.|..| . |  ||||...  |||||.||. ...| ..||||.| .                         ... |  |||| |||||||| ..  |
DDVRFYASEVTAALEYLHKRDFIYRDLKPDNIVLHQEGHVMLTDFDLSIQAKDSKKPVMKGSAQSTYVDTKICDHGFRTNSFCGTEEYLAPEMIRRCGHT

ISVDWWAIGTLAYEMLYGVPPFYDANTNAMYRSILRDEVVFP--EDASLDAIDLITKLLDKDPKTRLGSGPTDAEEIKAHPFF
  ||||  | . |||| |.||.|  |.| ..  |.. .| ||  .  | .. ||| ||| . |  |||..  ||..||.||||
KAVDWWTLGIVMYEMLFGCPPYYGNNKNETFYNIEKNHVKFPHDSYISNNCRDLIKKLLQRNPAKRLGCKMGDADDIKRHPFF
Kinase 90981.m00083.AA S_TKc 117-374 36 6.1e-106 359.17 SMART 1-231 (231) Show / Hide 
Range on Protein: 117-374
Range on HMM: 1-231/231
Sequence Identity: 36% (98 aa)

FDILKVLGKGSYGKVQLVRHKMTDLIYAMKSISKQLLSEHDLVSRIIAERDVLLSINHPFLVSARYAFQTETKIFLVLDYVQG--GELFSRLRAEQK---
..||...|||..||| ..||| |. |.|.| |.           .|. |...| . .||..|   ..||. .....|..|. |  |.||....  ..   
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

---FAEPRARYYIAELVSAIGYLHKKGIMHRDLKPENILFDKDGYIKLTDFGLVKRNMTKDSTTTTFCGTPEYLAPEMINGNEYTI-SVDWWAIGTLAYE
   | | .||.|......|. |.|..||.||||||||||.|.   ||..|||| ..        |||||||.|.|||..    |.  ..|||..| . ||
RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYE

MLYGVPPFYDANTNAMYRSILRDEVVFPEDASLDAIDLITKLLDKDPKTRLGSGPTDA--EEIKAHPFF
||.| |||.  . ..|.. |.          | .|.|.| |.|.|||. |..     .  ..||.||.|
MLCGYPPFP--QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 90981.m00083.AA p70 117-374 38 2.1e-102 346.51 In-house 1-299 (299) Show / Hide 
Range on Protein: 117-374
Range on HMM: 1-299/299
Sequence Identity: 38% (114 aa)

FDILKVLGKGSYGKVQLVRHKM---TDLIYAMKSISKQ--LLSEHDLVSRI------------------------IAERDVLLSINHPFLVSARYAFQTE
|  ||||||| |||| .||      |  ||||| . |   . .. |. .                           ||| .| ...|||..   |||||.
FELLKVLGKGGYGKVFQVRKVTGEDTGKIYAMKVLRKAKIVRNQKDTAHTREDEDKNDGNNNDNDDGLSKRLERTFAERNILEEVKHPFICDLHYAFQTN

TKIFLVLDYVQGGELFSRLRAEQKFAEPRARYYIAELVSAIGYLHKKGIMHRDLKPENILFDKDGYIKLTDFGLVKRNMTKDST----------TTTFCG
 | .|.|.|  |||||  |  .  . |  |..| .| . |...||..||  |||||||.. .. | ..|||||| |  . ...           | ||||
GKLYLILEYLHGGELFMHLERHGIWMEDTACFYLSEIICALEHLHQHGIIYRDLKPENCMLNQQGHVVLTDFGLCKESIHDGAVDEEDPENVNATHTFCG

TPEYLAPEMINGNEYTISVDWWAIGTLAYEMLYGVPPFYDANTNAMYRSILRDE--VVFPEDASLDAIDLITKLLDKDPKTRLGSGPTDAEEIKAHPFF
|.|| |||.. .  .   ||||. | | | || |.|||   |      .||.    .  |   . .. ||| ||| ..|..|.|.|| ||..|..||||
TIEYMAPEILMRCGHNHAVDWWSLGCLMYDMLTGGPPFTGENRKKTIDKILKGKQGLKLPPYLTHEMRDLIKKLLKRHPTQRWGAGPEDAADIQEHPFF
Kinase 90981.m00083.AA Pkinase 117-374 32 1.4e-92 318.65 Pfam 1-293 (293) Show / Hide 
Range on Protein: 117-374
Range on HMM: 1-293/293
Sequence Identity: 32% (97 aa)

FDILKVLGKGSYGKVQLVRHKMTDLIYAMKSISKQLLSEHDLVSRII-AERDVLLSINHPFLVSARYAFQTETKIFLVLDYVQGG----ELFSRLR--AE
. |....|.||.|.| . .|| |  |.|.| |.|.  ..  .....  .|  .....|||. |  ...|.....| .|..|..||    .||....  ..
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

QKF--AEPRARYYIAELVSAIGYLHKKGIMHRDLKPENILFDKDGYI----KLTDFGLVKRN-MTKDSTTTTFCGTPEYLAPEMIN-GNEYTISVDWWAI
 .|   |  .. |. ...... |.|..||.||||||||||.|..|.|    |..|||| |     ..| .|||||||.|.||| |. |..|. .||.|..
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSC

GTLAYEMLYGVPPFYDA------NTNAMYRSILRDEVVFPEDAS---------------------LDAIDLITKLLDKDPKTRLGSGPTDAEEIKAHPFF
| . |||| | |||...      . ..|.. |.. .. |... .                      ...|.|...|.|||| |..     ||.|. ||.|
GCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPT-----AEQILQHPWF
Kinase 90981.m00083.AA MAST 117-263 44 8.3e-63 190.44 In-house 1-150 (337) Show / Hide 
Range on Protein: 117-263
Range on HMM: 1-150/337
Sequence Identity: 44% (66 aa)

FDILKVLGKGSYGKVQLVRHKMTDLIYAMKSISKQLLSEHDLVSRIIAERDVLLSINHPFLVSARYAFQT--ETKIFLVLDYVQGGELFSRLRAEQ-KFA
|...|...|| ||.| ||.|| |  ..|||.| .| .     |  ...||..|  .  || |.. |.|||  ... ..|..|..||  .| ||.    . 
FEFIKCISKGAYGAVYLVKHKKTNDRFAMKVINCQDTIDKNQVDQVFVERNILTMYQNPFVVKMFYSFQTPCKKYLCMVMEYMEGGDCASLLRMYGNCMP

EPRARYYIAELVSAIGYLHKKGIMHRDLKPENILFDKDGYIKLTDFGLVK
|  |. ||||.| .. |||..|| ||||||.|.|.|..| |||||||| |
EWMAKMYIAETVLCLEYLHSYGIVHRDLKPDNMLIDSNGHIKLTDFGLSK
Kinase 90981.m00083.AA MAST 276-374 43 5.6e-46 138.06 In-house 229-337 (337) Show / Hide 
Range on Protein: 276-374
Range on HMM: 229-337/337
Sequence Identity: 43% (48 aa)

CGTPEYLAPEMINGNE-YTISVDWWAIGTLAYEMLYGVPPFYDANTNA-MYRSILR--DEVVFPED--------ASLDAIDLITKLLDKDPKTRLGSGPT
||||.|.||| |.|   |  .||||. |   || | |.||| . . .     .|.   .|. .||.         | .|.||| |||...||.|||..  
CGTPDYIAPEVILGQGTYGKPVDWWSMGIIMYEFLVGCPPFNGDTPEEMIFQNIINHDREIEWPEEGDPNDDDCMSPEAQDLIKKLLQPNPKKRLGAN--

DAEEIKAHPFF
 |.||| ||||
GADEIKQHPFF
Kinase 90981.m00083.AA S_TK_X 375-438 32 1.7e-15 58.74 SMART 1-79 (79) Show / Hide 
Range on Protein: 375-438
Range on HMM: 1-79/79
Sequence Identity: 32% (26 aa)

ASINWTNLEK--KTIPMQWKPPVQ----DLLDVSQFDQEFTGEAPKLTYEDPSLVGDNIQKK---------LQGFTYTN
..|.| .|..  |.|.  .||...    .  |.|.||.||| |.|.||  || |.. . |..           |||| .
RGIDWDKLYNQQKEIEPPFKPKIKEVYASPTDTSNFDPEFTEETPMLTPDDPPLSNSMWQNEMETEIPPDPFRGFTYVF
Kinase 90981.m00083.AA TyrKc 117-374 19 4.7e-14 4.53 SMART 1-280 (280) Show / Hide 
Range on Protein: 117-374
Range on HMM: 1-280/280
Sequence Identity: 19% (58 aa)

FDILKVLGKGSYGKVQLVRHKMTDLIYAMKSISKQLLSEHDLVSRIIAERDVLLSI--NHPFLVSARYAFQTE-------TKIFLVLDYVQGGELFSRLR
   .|.|| | .|.| . . |   .  | |.. .        .  .. |  .. ..  .|| .|    .  ..         ...|. |. .| | ..||
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR

AEQK-FAEPRARYYIAELVSAIGYLHKKGIMHRDLKPENILFDKDGYIKLTDFGLVKRNMTK-------DSTTTTF--CGTP----EYLAPEMINGNEYT
. .. .  .   ..     .   |||.|.. ||||   |.| .... .| .|||| .    .       |  ...   .|        .||| || ...|
KHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFT

ISVDWWAIGTLAYEML-YGVPPFYD------ANTNAMYRSILRDEVVFPED--------ASLDAIDLITKLLDKDPKTRLGSGPTDAEEIKAHPFF
.  | |. | . .|.. || .| ..       |. .. .   ..    |..        .. .  .....  . ||. |        .||  | .|
TKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRP-----TFSEI--HECF
Kinase 90981.m00083.AA Pkinase_C 394-440 38 6.3e-10 38.21 Pfam 1-46 (46) Show / Hide 
Range on Protein: 394-440
Range on HMM: 1-46/46
Sequence Identity: 38% (18 aa)

PVQDLLDVSQFDQEFTGEAPKLTYEDPSLVGDNIQKKLQGFTYTNDI
 | . .|.| || ||| |.|..|. |..    . |   .||||.|. 
QVKSPTDTSNFDPEFTDEPPMDTPPDWR-MSSGDQEPFRGFTYVNPD
Kinase 90981.m00083.AA Pkinase_Tyr 117-261 23 2.1e-07 25.71 Pfam 1-157 (270) Show / Hide 
Range on Protein: 117-261
Range on HMM: 1-157/270
Sequence Identity: 23% (37 aa)

FDILKVLGKGSYGKVQLVRHK----MTDLIYAMKSISKQLLSEHD-LVSRIIAERDVLLSI-NHPFLVSARYAFQ-TETK--IFLVLDYVQGGELFSRLR
  ..|.||.|..|.| . . |     |..  | |.. |.  .... .    ..|  .. .. .|| .|.   .    .    |..|. |...| | . ||
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR

A----EQKFAEPRARYYIAELVSAIGYLHKKGIMHRDLKPENILFDKDGYIKLTDFGL
.    .|..  ..   . ..  ..  ||. |.. ||||   |.| .... .| .||||
KHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGL