Gene 82576.m00144 (T.vaginalis)

82576.m00144

Species: T.vaginalis
Alias: TvagK0274, 82576.m00144
External Links:
Annotation:

Classification

Group: TKL
Family: TKL-Tvag1

Sequence

Name Sequence Type Origin Length Description Download
82576.m00144.AA Protein None 859 None Fasta, JSON
82576.m00144.kin_dom Protein Kinase Domain None 257 None Fasta, JSON

Protein domain

Protein domains of 82576.m00144.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 82576.m00144.AA TKL 31-278 23 3.5e-77 262.74 In-house 1-364 (364) Show / Hide 
Range on Protein: 31-278
Range on HMM: 1-364/364
Sequence Identity: 23% (88 aa)

IGKGGFGEVHRAIYKK--------TGTECAIKQIFAERLEGNRL-------------------------RRYIGEIETLARCDNMFLVPFIGFTAQPP--
||.||||||......         ||.. |.|..  .    . .                          . . ||  . |..   .|.|.|.  .||  
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

------------YTIVTEFMPNGSLDKYVRKKAGVEPLSGTQLTAIAIGIAHGMCHLHSLG--------IIHRDLKAANILLDSRLF-------------
            . ||.|..|.|||  |.            |.  .|..|| ||..||| .        ||||||| .|||.|. .              
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH---------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADW

-PRICDFGIAR-FEEHGSVGMTA------------------KIGTPNYMAPELIQST----------------NYDRKVDVYAFAMILYEMNENVRPFRG
 . |||||..| ....|.  .|.                  ..|||..||||... .                 |. |.|||.|...|.|.    ||...
CCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPYYD

LKVN---------DIFKAVIQNDERPEFT------------KVTPQKMQELIRRCWHREPAERPTFEEIRDEF
.. .         ..|. |... .||.              . .|. | .|. .||. .| .||.|.|| ...
YPYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
Kinase 82576.m00144.AA TKL-Unique 27-278 27 5.9e-66 225.42 In-house 1-290 (290) Show / Hide 
Range on Protein: 27-278
Range on HMM: 1-290/290
Sequence Identity: 27% (81 aa)

FGDVIGKGGFGEVHRAIYKKTGTECAIKQIFAERLEGNRLRR-YIGEIETLARCD-NMFLVPFIGFTA----QPP-YTIVTEFMPNGSLDKYVR------
|. .|| ||.|.| .....  |.. ||||.. . .  |....  . |. .. . .   ..| ..|...    .|| . ||.|..| |||...        
FWNKIGEGGYGQVYKGKWR--GYPVAIKQFHPNEDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNNNN

-KKAGVEPLSGTQLTAIAIGIAHGMCHLHSLG--IIHRDLKAANILLDSR-----LFPRICDFGIARFEEHG---SVGMT------AKIGTPNYMAPELI
   .   .|.  |   .|| || ||..||...  |||||||  |.|.|..     .  .|||||...|       ....        ..|....||||..
NNNNNNCKLNMQQRVKMAIDIAQGMYYLHHCEPPIIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFRWMAPEVL

QS--TNYDRKVDVYAFAMILYEMNENVR------PFRGLKVNDIFKAVIQ--NDERPEFTKVTPQKMQELIRRCWHREPAERPTFEEIRDEF
 .  . |..|.|||.|...|.|. .. .      |..|.  . ....| .     ||.     |.  ..||..|||..| .||.|.||. . 
RMNFCQYSEKSDVYSFGIVLWEIATRKITKTYKKPYQGMDQEQWCEMVHYMEENYRPPIPNHCPKEYRDLIQQCWHHDPSQRPSFDEIIHRL
S_TKc 82576.m00144.AA S_TKc 25-279 28 1.5e-64 221.66 SMART 1-231 (231) Show / Hide 
Range on Protein: 25-279
Range on HMM: 1-231/231
Sequence Identity: 28% (78 aa)

FDFGDVIGKGGFGEVHRAIYKKTGTECAIKQIFAERLEGNRLRRYIGEIETLARCDNMFLVPFIGFTAQPPYTIVTEFMPN--GSLDKYVRKKAGV---E
......||||.||.|.... |||| ..|||.|          .. . ||. | . .  ..| ....     . .|.|....  |.| .| .|. .     
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQDDHLYMVMEYCDGDLGDLFDYIKKRGRHGLRF

PLSGTQLTAIAIGIAHGMCHLHSLGIIHRDLKAANILLDSRLFPRICDFGIARFEEHGSVGMTAKIGTPNYMAPELIQSTNYDR-KVDVYAFAMILYEMN
|..  .   ..  |. .. ..||.|||||||| .|||||.     |||||.||.        |  .|||.|||||..    |.. |.|....  ||||| 
PFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEML

ENVRPFRGLKVNDIFKAVIQNDERPEFTKVTPQKMQELIRRCWHREPAERPTFEEIRD--------EFA
    ||.   .. .|| .             .. . ..||.|....|..|||  |.          .. 
CGYPPFP--QMQMMFKKIG------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Pkinase 82576.m00144.AA Pkinase 25-278 26 3.4e-59 207.76 Pfam 1-293 (293) Show / Hide 
Range on Protein: 25-278
Range on HMM: 1-293/293
Sequence Identity: 26% (78 aa)

FDFGDVIGKGGFGEVHRAIYKKTGTECAIKQIFAERLEGNRLRRYIG--EIETLARCDNMFLVPFIGFTAQPPYTI-VTEFMPNG----SLDKYVR--KK
. .| .||.|.||.| ... |.|| . |.|.|  .. . . ... .   ||. ..|..  . | ....   ...   |.|....|    .|  |..  ..
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

AGVEPLSGTQLTAIAIGIAHGMCHLHSLGIIHRDLKAANILLDSRLFP----RICDFGIARF--EEHGSVGMTAKIGTPNYMAPELIQ-STNYDRKVDVY
 ..  .|  ..  ..  |. |. ..|| |||||||| .|||.|..  .    .|||||.|..  . ..|  ||   |||.|||||.|. .. |..|||..
GCFY-FSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS--MTTFCGTPWYMAPEVIRGGQYYGPKVDMW

AFAMILYEMNENVRPFRGL------KVNDIFKAVIQNDERPEFTKVTP-------------------QKMQELIRRCWHREPAERPTFEEIRDE--F
..  |||||     ||.|         . ... . . . . .. .  .                   . ....|..|... |..|||.|.|     |
SCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase 82576.m00144.AA MLK 25-278 26 1.2e-57 197.78 In-house 1-291 (291) Show / Hide 
Range on Protein: 25-278
Range on HMM: 1-291/291
Sequence Identity: 26% (76 aa)

FDFGDVIGKGGFGEVHRAIYKKTG---TECAIKQIFA-------ERLEGNRLRRYIGEIETLARCD-NMFLVPFIGFTAQP-P-YTIVTEFMPNGSLDKY
..|  .||.|.||.|... ....     . |.|...|       .  |   ... . .   | .   .   ..| |  .|| . . ||.|....|||  .
IQFHEWIGSGSFGKVWKGRWRNKDIVAKIVAVKRVRARIFDKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQPPCHFCIVMEYCEGGSLYNV

VRK-KAGVE----------PLSGTQLTAIAIGIAHGMCHLHSLG---IIHRDLKAANILLDS------RLFPRICDFGIAR-FEEHGSVGMTAKIGTPNY
 .  . . .            .  ..  .|  .|.||  |||.    |||||||  |||.|        .  .|||||..| . ...   |. ..||. .
LHGARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHSMAPKPIIHRDLKSHNILIDEICHDMHHGTLKICDFGTSRDWHQMC-TNMMSNAGTYAW

MAPELI---QSTNYDRKVDVYAFAMILYEMNENVRPFR-GLKVNDIFKAVIQNDERPEFTKVTPQKMQELIRRCWHREPAERPTFEEIRDEF
|||| |   ... |..|.||. ....|.||     |.. ...   |.  |..| .||   .  |  . .|. .||. .|..||.| .|  ..
MAPEVIQQFRCEKYSEKCDVWSWGVVLWEMLTREVPYKQHYDPMAIAWWVAYNGLRPPIPSTCPEHWKKLMKQCWNQDPHKRPSFRQIVQHL
Kinase 82576.m00144.AA TyrKc 25-278 25 1.3e-55 192.02 SMART 1-280 (280) Show / Hide 
Range on Protein: 25-278
Range on HMM: 1-280/280
Sequence Identity: 25% (73 aa)

FDFGDVIGKGGFGEVHRAIYKKTGTECAIKQIFAERLEGNRLRRYIGEIETLARC--DNMFLVPFIGFTAQ--------PPYTIVTEFMPNGSLDKYVRK
  .|...| | ||||.....|   ...|.| . ..      ..  . |.. . .   ..  .| ..|   |        .|. ||.|.||.|.|..| ||
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRK

KAGVEPLSGTQLTAIAIGIAHGMCHLHSLGIIHRDLKAANILLDSRLFPRICDFGIARFEEHG-------SVGMTAK-IGTP-----NYMAPELIQSTNY
. .   |.  .|  ... || || .||| ..||||| | |.|.....  .|.||| .|. ...       .. ....  |.        |||| |.   .
HRPK--LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKF

DRKVDVYAFAMILYEMNENVRPFRGL-----KVNDIFKAVIQNDERPEFTKV--------TPQKMQELIRRCWHREPAERPTFEEIRDEF
  | ||..|   ..|.  .  .         . |.   . ... .|..  .          |..| .....|||..|..||||.||...|
TTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase 82576.m00144.AA TK 25-278 14 4.1e-53 176.02 In-house 1-486 (486) Show / Hide 
Range on Protein: 25-278
Range on HMM: 1-486/486
Sequence Identity: 14% (70 aa)

FDFGDVIGKGGFG---EVHRAIYKKTG-------------------------TECAIKQIFAERLEGNRLRRY---------------IGEIETLA--RC
  .|...|.| ||   ||......  .                         |..|.|.. ..  .  . ..                  |.. .    .
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

DNMFLVPFIG-FTAQ------------PPYTIVTEFMPNGS----LDKYVRKKAGVEP------------------------------------------
.   .| ..|  | .            .|. ||.|.||.|.    |..| ||. . .                                           
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

-------------------------------LSGTQLTAIAIGIAHGMCHLHSL------GIIHRDLKAANILLDSRLF-----------PRICDFGIA-
                               |.  ||  ..  || || .|||.      ...|||| | |.|.....             .|.||| . 
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSR

-------RFEEHGSVGMTAKIGTPNY--------------------------MAPELIQ---------STNYDRKVDVYAFAMILYEMNENV-RPFRGLK
       |  ....   ... .. .                           |||| ..            .  | ||..|   ..|.  .   |. |  
QGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGM

VN---------DIFKAVIQND--------------ERPEFTKVTP--------------QKMQELIRRCWHREPAERPTFEEIRDEF
 |         . .   ...                |..  .  |              . ...|...|||..|..||||.......
SNQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL
Kinase 82576.m00144.AA Pkinase_Tyr 25-278 28 9.2e-53 179.32 Pfam 1-270 (270) Show / Hide 
Range on Protein: 25-278
Range on HMM: 1-270/270
Sequence Identity: 28% (76 aa)

FDFGDVIGKGGFGEVHRAIYK----KTGTECAIKQIFAERLEGNR--LRRYIGEIETLARC-DNMFLVPFIGFTA--QPP--YTIVTEFMPNGSLDKYVR
  || ..|.| ||||.....|    .|....|.| .  |        ..  . |....    ..  .| ..|     . |  . ||.|.||.|.|..| |
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR

KK-AGVEPLSGTQLTAIAIGIAHGMCHLHSLGIIHRDLKAANILLDSRLFPRICDFGIARFEEHGSVG---MTAKIGTPNYMAPELIQSTNYDRKVDVYA
|.  . .||.  .|  ... || || .|.| ..||||| | |.|... .. .||||| ||  .. .      .        |||| |.   .  | ||..
KHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECINYGKFTTKSDVWS

FAMILYEMNENV-RP-FRGLKVNDIFKAVIQNDERPEFTKVTPQKMQELIRRCWHREPAERPTFEEIRDEF
|   ..|.      | . |.. ....... .. .| .  . .|... .|...||| .|..||||.||. ..
FGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYRMPCPENCPDEIYDLMKQCWHYDPEDRPTFSEIHEQL
Kinase 82576.m00144.AA STE 25-273 22 4.1e-50 172.8 In-house 1-350 (359) Show / Hide 
Range on Protein: 25-273
Range on HMM: 1-350/359
Sequence Identity: 22% (79 aa)

FDFGDVIGKGGFGEVHRAIYKK---------------TGTECAIKQIFAERLE---------------GNRLRRYIGEIETLARCD--NMFLVPFIGFTA
... ..||||.||.|..|...|               ||. .||||.  |. .                . . ... ||... .|.    . | ..|   
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

QPP--------YTIVTEFMPNGSLDKYVRKKAGV-EPLS----------GTQLTAIAIGIAHG-MCHLHSLGIIHRDLKAANILLDSRLFPRICDFGIAR
.            |. |.|..||||. ...| |. .||.           .|. .|.  | .| . .|||..|||||.|.|||||       .||||.. 
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-----VKLCDFGVCG

-FEEHGS--------------VGMT-AKIGTPNYMAPELIQS------TNYDRKVDVYAFAMILYEMNENVRPF---RGLKV--NDIFKAVIQN------
 ......              ....   .||| .|||| ||         ||.|.|.. .   . || .   |.     ...  . .|. ..|.      
QLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQLC

---DERPEFTKVTP-------------------QKMQELIRRCWHREPAERPTFEE
   .. | .   .                    ..... |..|  ..| .||| ..
IVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQ
Kinase 82576.m00144.AA RIPK 31-278 28 1.3e-49 167.29 In-house 1-290 (290) Show / Hide 
Range on Protein: 31-278
Range on HMM: 1-290/290
Sequence Identity: 28% (84 aa)

IGKGGFGEVHRAIYKKTGTECAIKQ----IFAERLEGNRLRRYIGEIETLARCDNMFLVPFIGFTAQP------P-YTIVTEFMPNGSLDKYVRKKAGV-
.|.|||||| .|  .. |.. |.|       .. ..       . | . ... .. . ||  ||. ..        | ||.|.|.|||| .    |    
VGGGGFGEVFKARHRHWGDWVAKKCKPCKHCHTHMDDQERMYQKEEAKHMHKLRCEHIVPIYGFCQCEEWDCDCKLYGIVMEYMENGSLWHFLHTKWPYQ

---EPLSGTQLTA-IAIGIAHGMCHLHSLG--IIHRDLKAANILLDSRLFPRICDFGIARFEEHG---S--------VGMTAKI--GTPNYMAPELIQST
    |..   |.  .   |. ||| ||| .  ||||||| .|||.|. .   | ||| | . .     .         .|. |   ||  ||.||..   
HHPDPWP---LRCRMIHEISCGMCYLHSMNPPIIHRDLKPENILVDNNFHVKIADFGLATWMMWSHSHQDRCNQREVYSMKSKNRWGTLSYMPPEHFRTD

NYDR------KVDVYAFAMILYEMNENVRPFRGLKVNDIFKAVIQNDERPEFTKV---TP-----QKMQELIRRCWHREPAERPTFEEIRDEF
| ..      | ||| ||....|   .  |. . |   .. .... . ||. . |   .|     ..| ||..|||. .| .||.| |.....
NKKPIKVVTPKYDVYSFAIVMWEVLTQKHPYEDRKCMMMIMMCCKQGHRPCLQPVPEYWPEPPHCEQMIELMQRCWQQDPNDRPCFQECEEWT
Kinase 82576.m00144.AA Dicty5 98-282 37 6.4e-48 163.01 In-house 76-260 (260) Show / Hide 
Range on Protein: 98-282
Range on HMM: 76-260/260
Sequence Identity: 37% (70 aa)

IVTEFMPNGSLDKYVRKKAG--VEPLSGTQLTAIAIGIAHGMCHLHSLGIIHRDLKAANILLDSRLFPRICDFGIARFEEHGSVGMTAKIGTPNYMAPEL
.|||.  ||||  | . .      |..  |   .||.|| .| |||| .|||||||  |.|.  ..   | |||. || .    .||  .||...||.||
HVTEYCHNGSLFNYLNDQRKTTGQPIAYFQQLHMAIDIAQSMRHLHSMNIIHRDLKSMNFLITENWKIKIIDFGTSRFVDN-RYHMTMHVGTQCWMACEL

IQSTNYDRKVDVYAFAMILYEMNENVRPFRGLKVNDIFKAV-IQNDERPEFTKVTPQKMQELIRRCWHREPAERPTFEEIRDEFARGK
 ..  |. |.|||.|. .|.||     |.  .  | .  .| ..  |||.  |  |     ||  ||   |  ||.| || . | .  
FNGQPYHQKCDVYSFGIVLWEMFTRKEPYDNI--NNWNIPVMVMKGERPTIPKDCPTEISNLIKKCWQQKPHNRPSFKEICKYFESII
Kinase 82576.m00144.AA LRRK 95-280 30 8.8e-47 161.73 In-house 129-351 (351) Show / Hide 
Range on Protein: 95-280
Range on HMM: 129-351/351
Sequence Identity: 30% (68 aa)

PYTIVTEFMPNGSLDKYVRKKAGVE------PLSGTQLTAIAIGIAHGMCHLHSLG--IIHRDLKAANILL---D---------SRLFPRICDFGIAR--
|...|.|..|.|.|... ..|.  .       .| . .  ||. || || .|||    |||||||  ||||   .               |.|||| |  
PLCMVMEYAPHGDLYHFLHNKKQDGFHFMKAHISWMLKLKIALQIAKGMEYLHSHNPPIIHRDLKSPNILLWSSPQNHSPNYPNAHVCAKIADFGISRMF

FEEHGSVGMTAKIGTPNYMAPELIQST---NYDRKVDVYAFAMILYE-MNENVRPFRGLK-V-----NDIFKAVIQNDERPEFTKV-TPQ-----KMQEL
.  | .| .. . |.| .|||| .. .   .|. |||.|.|.|||.| .   ..||.... .     . ...  |..  || .     |.      .|.|
QCFHMGVAKG-CVGNPGWMAPEIMRYNGEEEYTEKVDCYSFGMILWELLTRQHHPFDEHDFFDHMQWMEQIEDKIIEGLRPTIPQHYCPPCQPWHMYQDL

IRRCWHREPAERPTFEEIRDEFAR
|  ||. .| .||.|..| .    
IQHCWQHDPKKRPHFSQIVKRLSQ
Kinase 82576.m00144.AA Dicty4-Unclassified 25-278 31 3.6e-45 152.63 In-house 1-263 (263) Show / Hide 
Range on Protein: 25-278
Range on HMM: 1-263/263
Sequence Identity: 31% (84 aa)

FDFGDVIGKGGFGEVHRAIYKKTGTECAIKQIFAERLEGNR---LRRYIGEIETLARCDNMFLVPFIGFTAQP-----PYTIVTEFMPNGSLDKYVR---
      |||| | .||. . |  | . |.| .| |     |   .  .  |.| |       ||   |    |      . ||.|||. | |   .    
IQIDQFIGKGHFSKVHKGNWK--GKDVAVK-KFNENKFKFREEMIQDFKKEVEILGSIQHPNLVKCYGYCINPRSHKSTMCIVMEFMHKGNLFEVIHSKP

--KKAGVEPLSGTQLTAIAIGIAHGMCHLHSLGIIHRDLKAANILLDSRLFPRICDFGIARFEEHGSVGMTAKIGTPNYMAPELIQSTNYDRKVDVYAFA
  ..  .  |  |   ..|. || || |||.  .||||.|..|||.|     .| ||||.| .      ||.  |||   .||      |  | ||| .|
SEQQQPIK-LDDTLIIKYAFDIAQGMQHLHTRNFIHRDIKSSNILMDKHFNIKIADFGISR-VIDFNFNMTTIAGTPKWESPECLMHESYNQKSDVYSYA

MILYEMNENVRPFRGLK-VNDIFKAVIQNDERPEFTKVTPQKMQELIRRCWHREPAERPTFEEIRDEF
|.|||.     |. .   . ..   |     ||.     .  .. ||  ||| .|  |||...| .  
MMLYELATGDEPYQEIQSIMNAARSVCDKKLRPKIPDNCDNFWKKLIKWCWHNDPNKRPTMNQIIQYL
Kinase 82576.m00144.AA Dicty4 98-274 32 2.2e-44 146.04 In-house 79-269 (277) Show / Hide 
Range on Protein: 98-274
Range on HMM: 79-269/277
Sequence Identity: 32% (62 aa)

IVTEFMPNGSLDKYVRK----KAGVEPLSGTQLTA---IAIGIAHGMCHLHS--LGIIHRDLKAANILLDSRLFPRICDFGIAR-FEEHG--SVGMTAKI
||||.|| |.| .  ..    .    .|. .  ..   .|. .| || .||.    |||||||..|.| |  .   .||||... . .|   . .... .
IVTEYMPKGNLYSLLHDKPSEQQQSIKLDWPLIKRAMRMAFDAARGMNWLHCCNPVIIHRDLKSHNLLVDKNWRVKVCDFGLSQYMKKHEDHKDNQMTAC

GTPNYMAPELIQSTNYDRKVDVYAFAMILYEMNENVRPFR--GLKVNDIFKAVIQNDERPEFTKVTPQKMQELIRRCWHREPAERPTFEEI
||| .||||  ..  |. |.||| |...|.|.     |.   .     .. || .  .||.  . .| .  .|| .||. .|  ||.||||
GTPCWMAPEVMMHQPYNEKADVYSFGIVLWEILTRQEPYQKHHMPYMQFVRAVCNKKLRPPIPDWCPPSWKHLIQWCWDHDPQHRPSFEEI
Kinase 82576.m00144.AA LRRK 25-56 20 2e-06 18.42 In-house 1-59 (351) Show / Hide 
Range on Protein: 25-56
Range on HMM: 1-59/351
Sequence Identity: 20% (12 aa)

FDFGDVIGKGGFG-EVHRAIYKK--------------------------TGTECAIKQI
. ..  ||.|||| .|.||....                           ... |||..
LKIEEQIGRGGFGTFVYRAKWRGQPVHVCRMHQKMLQPYMYQGARNSYDMCQWVAIKKW
Kinase 82576.m00144.AA Dicty4 25-54 40 4.5e-05 13.06 In-house 1-28 (277) Show / Hide 
Range on Protein: 25-54
Range on HMM: 1-28/277
Sequence Identity: 40% (12 aa)

FDFGDVIGKGGFGEVHRAIYKKTGTECAIK
 .... ||||.||||.... .  |.| |.|
INIEQRIGKGSFGEVYKGTWR--GKEVAVK
Kinase 82576.m00144.AA Dicty5 27-54 46 0.119772 1.44 In-house 3-28 (260) Show / Hide 
Range on Protein: 27-54
Range on HMM: 3-28/260
Sequence Identity: 46% (13 aa)

FGDVIGKGGFGEVHRAIYKKTGTECAIK
|.|.|  |  | |   |||  |   |||
FHDWIASGASGRVYNGIYK--GMDVAIK