Gene 91727.m00169 (T.vaginalis)

91727.m00169

Species: T.vaginalis
Alias: TvagK0317, 91727.m00169
External Links:
Annotation:

Classification

Group: TKL
Family: TKL-Tvag1

Sequence

Name Sequence Type Origin Length Description Download
91727.m00169.AA Protein None 960 None Fasta, JSON
91727.m00169.kin_dom Protein Kinase Domain None 249 None Fasta, JSON

Protein domain

Protein domains of 91727.m00169.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 91727.m00169.AA TKL 177-421 27 1.3e-90 307.29 In-house 1-364 (364) Show / Hide 
Range on Protein: 177-421
Range on HMM: 1-364/364
Sequence Identity: 27% (101 aa)

IGRGQSGTVYLGHFKDSD--------DNIAIKVLSKQTLSQADVES----------------------YRREVYFLTILS---HPSLTKFCGYTEDAP--
||.| .|.|| |...  .          .|.|.....  .  .  |                        .|.. . ..|   || . .| ||  . |  
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

------------FYICTEFMSGGSLYHKLRNNPEQLNPTTRSLIALTVARGLEYLHS--------KGVIHRDLKSLNVLLDDNNN--------------A
            ..| .|...||||.| |        .  |  .|| .|||..||||        ...||||||| |.|.|.|..              .
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH-------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWCC

KICDFGMVRTRDSRP---------------------MTGMIGTVHWMAPEVLMSTPF---------------YDERVDVYSFGIFLWELLTGQMPYKDMQ
||||||  |. . .                          .||  |||||||. ...               |.|..||||||| |||.||.. ||.|. 
KICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPYYDYP

ANQII---------RTVTELGERPPIP------------EDCPQHLAKLITKCWSQDPEDRPTMAKVVAEL
 ...|           | . |.|||||            .|||....||...||..|||.||.. ... .|
YMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
Kinase 91727.m00169.AA TKL-Unique 173-421 33 7.2e-85 288.27 In-house 1-290 (290) Show / Hide 
Range on Protein: 173-421
Range on HMM: 1-290/290
Sequence Identity: 33% (99 aa)

FEKTIGRGQSGTVYLGHFKDSDDNIAIKVLSKQTLSQADVES-YRREVYFLTILS-HPSLTKFCGYTE----DAP-FYICTEFMSGGSLYHKLR------
| ..||.| .|.|| | .. ..  .|||..... .|  ...   ..||  .  |  || .... ||.     ..| ..| .|...|||||  |       
FWNKIGEGGYGQVYKGKWRGYP--VAIKQFHPNEDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNNNN

---NNPEQLNPTTRSLIALTVARGLEYLHSKG--VIHRDLKSLNVLLDDN-----NNAKICDFGMVRTRDSR---PMT--------GMIGTVHWMAPEVL
   ||   ||.  |  .|. .|.|..|||...  .|||||||.|.|.| |     .|.|||||| .......   . .        . .|.  |||||||
NNNNNNCKLNMQQRVKMAIDIAQGMYYLHHCEPPIIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFRWMAPEVL

MST-PFYDERVDVYSFGIFLWELLTGQM------PYKDMQANQIIRTVTE--LGERPPIPEDCPQHLAKLITKCWSQDPEDRPTMAKVVAEL
..    |.| .||||||| |||..|..       ||..|  .|.. .|..   . |||||..||. . .||..|| .||..||.   .. .|
RMNFCQYSEKSDVYSFGIVLWEIATRKITKTYKKPYQGMDQEQWCEMVHYMEENYRPPIPNHCPKEYRDLIQQCWHHDPSQRPSFDEIIHRL
Kinase 91727.m00169.AA Dicty4 171-423 35 1.9e-82 274.79 In-house 1-277 (277) Show / Hide 
Range on Protein: 171-423
Range on HMM: 1-277/277
Sequence Identity: 35% (100 aa)

CVFEKTIGRGQSGTVYLGHFKDSDDNIAIKVL--SKQTLSQADVESYRREVYFLTILSHPSLTKFCGYTE---DAP--FYICTEFMSGGSLYHKLRN---
 ..|. ||.|  |.||.|  . ..   |.|.|   .|.....  .. |.||  .  ..|| . .| |.      .|  . |.||.|. |.||  |..   
INIEQRIGKGSFGEVYKGTWRGKE--VAVKKLNNHNQNFDENMLNEFRKEVHIMCKIRHPNICLFMGACTAPRSHPGKMCIVTEYMPKGNLYSLLHDKPS

---NPEQLN-PTTRS--LIALTVARGLEYLHSKG--VIHRDLKSLNVLLDDNNNAKICDFGMVR----TRDSRP-MTGMIGTVHWMAPEVLMSTPFYDER
      .|  |. ..  ..|. .|||. .||.    .||||||| | | |.|...|.||||  .      |    .....||. ||||||.|. | |.| 
EQQQSIKLDWPLIKRAMRMAFDAARGMNWLHCCNPVIIHRDLKSHNLLVDKNWRVKVCDFGLSQYMKKHEDHKDNQMTACGTPCWMAPEVMMHQP-YNEK

VDVYSFGIFLWELLTGQMPYK--DMQANQIIRTVTELGERPPIPEDCPQHLAKLITKCWSQDPEDRPTMAKVVAE--LQD
.||||||| |||.||.| ||    |   |..| | . ..||||| .||  ...||..||. ||. ||... .. .  |  
ADVYSFGIVLWEILTRQEPYQKHHMPYMQFVRAVCNKKLRPPIPDWCPPSWKHLIQWCWDHDPQHRPSFEEIIQRRILEH
Kinase 91727.m00169.AA MLK 171-421 34 1.5e-79 270.56 In-house 1-291 (291) Show / Hide 
Range on Protein: 171-421
Range on HMM: 1-291/291
Sequence Identity: 34% (100 aa)

CVFEKTIGRGQSGTVYLGHFKDSD---DNIAIKVLSKQT----LSQADVESYRREVYFLTILSHPS----LTKFCGYTEDA-P-FYICTEFMSGGSLYHK
  |.. || | .| |..| ..  |     .|.|     .     . .  .  ..|.. | |||||       .| |   .  . |.| .|...|||||. 
IQFHEWIGSGSFGKVWKGRWRNKDIVAKIVAVKRVRARIFDKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQPPCHFCIVMEYCEGGSLYNV

L---RNNPE----------QLNPTTRSLIALTVARGLEYLHSKG---VIHRDLKSLNVLLDD------NNNAKICDFGMVRTRDSR-P-MTGMIGTVHWM
|   |....             .     .|| .|||..||||.    .||||||| |.|.|.      . ..|||||| .|   ..   |....||. ||
LHGARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHSMAPKPIIHRDLKSHNILIDEICHDMHHGTLKICDFGTSRDWHQMCTNMMSNAGTYAWM

APEVL--MSTPFYDERVDVYSFGIFLWELLTGQMPYK-DMQANQIIRTVTELGERPPIPEDCPQHLAKLITKCWSQDPEDRPTMAKVVAEL
||||.       |.| .||.|.|. |||.||...||| .. . .|.  |.. |.||||| .|| |..||...||.|||..||... .| .|
APEVIQQFRCEKYSEKCDVWSWGVVLWEMLTREVPYKQHYDPMAIAWWVAYNGLRPPIPSTCPEHWKKLMKQCWNQDPHKRPSFRQIVQHL
Kinase 91727.m00169.AA Pkinase_Tyr 171-421 33 1.4e-73 249.82 Pfam 1-270 (270) Show / Hide 
Range on Protein: 171-421
Range on HMM: 1-270/270
Sequence Identity: 33% (91 aa)

CVFEKTIGRGQSGTVYLGHFK----DSDDNIAIKVLSKQTLSQAD--VESYRREVYFLTIL-SHPSLTKFCGYTE--DAP--FYICTEFMSGGSLYHKLR
 .| |..|.|. |.||.|. |    . .   |.|.| |.. .. .   |.  ||.  .. | .|| . .. |     . |   || .|.| .|.|.. ||
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR

NN---PEQLNPTTRSLIALTVARGLEYLHSKGVIHRDLKSLNVLLDDNNNAKICDFGMVRTR----DS-RPMTGMIGTVHWMAPEVLMSTPFYDERVDVY
..   ...|.. .   ... .|.|.|||.||. |||||   |.|...|| .||||||. |.        |  .|    . |||||...    . .  ||.
KHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECINYGK-FTTKSDVW

SFGIFLWELLT-GQMP-YKDMQANQIIRTVTELGERPPIPEDCPQHLAKLITKCWSQDPEDRPTMAKVVAEL
|||. .||..| |..| |..|  ..... ..| |.| |.||.||. . .|...|| .|||||||.. .. .|
SFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYRMPCPENCPDEIYDLMKQCWHYDPEDRPTFSEIHEQL
Kinase 91727.m00169.AA LRRK 171-423 27 8.5e-70 238.19 In-house 1-351 (351) Show / Hide 
Range on Protein: 171-423
Range on HMM: 1-351/351
Sequence Identity: 27% (97 aa)

CVFEKTIGRGQSG-TVYLGHFK--------------------------DSDDNIAIKVLSKQ--TLSQADVE----------------------------
 ..|. |||| .| .|| . ..                          |.. ..|||.. .   |    | .                            
LKIEEQIGRGGFGTFVYRAKWRGQPVHVCRMHQKMLQPYMYQGARNSYDMCQWVAIKKWNRDPMTID-NDCNNSNNNNNLNNNNSEQVEDMDQNHEDCCR

---SYRREVYFLTILSHPSLTKFCGYTEDAPFYICTEFMSGGSLYHKLRNNPE--------QLNPTTRSLIALTVARGLEYLHSKG--VIHRDLKSLNVL
   ..|.||. .  | ||.. .  |.. . |. . .|... |.||| |.|. .         ......  ||| .|.|.|||||.   .||||||| |.|
AFREFRHEVWIMSHLNHPNIVSLKGFCIH-PLCMVMEYAPHGDLYHFLHNKKQDGFHFMKAHISWMLKLKIALQIAKGMEYLHSHNPPIIHRDLKSPNIL

L--DDNN----------NAKICDFGMVR--TRDSRP-MTGMIGTVHWMAPEVLMST--PFYDERVDVYSFGIFLWELLTGQ-MPYKDMQ-ANQI--IRTV
|   ..|          .|||.|||  |  . .      |. |.  |||||..  .    |.| ||.||||..||||||.|  |. ...   ..  . ..
LWSSPQNHSPNYPNAHVCAKIADFGISRMFQCFHMGVAKGCVGNPGWMAPEIMRYNGEEEYTEKVDCYSFGMILWELLTRQHHPFDEHDFFDHMQWMEQI

TE---LGERPPIPED-CPQ-----HLAKLITKCWSQDPEDRPTMAKVVAELQD
 .    | ||.||.. ||.      . .||..||..||..||.. ..|  | .
EDKIIEGLRPTIPQHYCPPCQPWHMYQDLIQHCWQHDPKKRPHFSQIVKRLSQ
Kinase 91727.m00169.AA Dicty5 171-425 35 4.1e-69 235.91 In-house 1-260 (260) Show / Hide 
Range on Protein: 171-425
Range on HMM: 1-260/260
Sequence Identity: 35% (93 aa)

CVFEKTIGRGQSGTVYLGHFKDSDDNIAIKVLSKQTLSQADVESYRREVYFLTILS--HPSLTKFCG-YTEDAPF-YICTEFMSGGSLYHKLRNNPE---
  | . |  | ||.|| | .|  |  .||||.|       | ... |||  . |    || .... |  . .    .. ||. . |||   |.       
VSFHDWIASGASGRVYNGIYKGMD--VAIKVYSQENCMCFDWNEFYREVTIMSIFQSDHPNFIRCYGAHQYNDKYPFHVTEYCHNGSLFNYLNDQRKTTG

-QLNPTTRSLIALTVARGLEYLHSKGVIHRDLKSLNVLLDDNNNAKICDFGMVR-TRDSRPMTGMIGTVHWMAPEVLMSTPFYDERVDVYSFGIFLWELL
  .   ..  .|. .|.....|||...|||||||.|.|.  |  .|| |||  |       ||  .||  |||.|.  . | |.. .||||||| |||..
QPIAYFQQLHMAIDIAQSMRHLHSMNIIHRDLKSMNFLITENWKIKIIDFGTSRFVDNRYHMTMHVGTQCWMACELFNGQP-YHQKCDVYSFGIVLWEMF

TGQMPYKDMQANQIIRTVTELGERPPIPEDCPQHLAKLITKCWSQDPEDRPTMAKVVAELQDSK
|   ||...    |   |   |||| || |||   ..|| ||| | |  ||.  .... ..   
TRKEPYDNINNWNIPVMVMK-GERPTIPKDCPTEISNLIKKCWQQKPHNRPSFKEICKYFESII
Kinase 91727.m00169.AA Pkinase 171-421 26 1e-66 232.77 Pfam 1-293 (293) Show / Hide 
Range on Protein: 171-421
Range on HMM: 1-293/293
Sequence Identity: 26% (77 aa)

CVFEKTIGRGQSGTVYLGHFKDSDDNIAIKVLSKQTLSQADVESYRR--EVYFLTILSHPSLTKFCGYTE-DAPFYICTEFMSGG----SLYHKLR-NNP
 .....||.| .|.||..| |.. .  |.|...|.. .    .. ||  |.. .  |.||   .. .. | .   |...|.. ||    .|.. ..  . 
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

EQL--NPTTRSLIALTVARGLEYLHSKGVIHRDLKSLNVLLDDNNNA----KICDFGMVR---TRDSRPMTGMIGTVHWMAPEVLMSTPFYDERVDVYSF
  .   . .   ... ..|||||.||.|.||||||. |.|.|.|..     ||||||  .   .  .. ||.  || ..|||||... . |. .||..|.
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSC

GIFLWELLTGQMPYKDM------QANQIIRTVTELGERPPIPEDCP-------------------QHLAKLITKCWSQDPEDRPTMAKVVAE--L
|. |.|.|.|. |...         .|.|. . .   . ..|..|.                   . . ..|..|. .||..||| . ..    .
GCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase 91727.m00169.AA S_TKc 171-426 27 4.5e-66 226.75 SMART 1-231 (231) Show / Hide 
Range on Protein: 171-426
Range on HMM: 1-231/231
Sequence Identity: 27% (75 aa)

CVFEKTIGRGQSGTVYLGHFKDSDDNIAIKVLSKQTLSQADVESYRREVYFLTILSHPSLTKFCGYTEDAPFYICTEFMSG--GSLYHKLRNNPEQ----
  . ..||.|  |.||... |...   |||...         |. |||.  |    || . |. .. .|  .|...|...|  |.|.. ..... .    
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQDDHLYMVMEYCDGDLGDLFDYIKKRGRHGLRF

-LNPTTRSLIALTVARGLEYLHSKGVIHRDLKSLNVLLDDNNNAKICDFGMVRTRDSRPMTGMIGTVHWMAPEVLMSTPFYDE-RVDVYSFGIFLWELLT
 ... .   ..  ....|||.||.|.||||||  |.|||.  . ||||||. |       | ..|| ..||||||     |.  ..|..|.|. |.|.|.
PFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-----TTFCGTPWYMAPEVL----GYGKCKCDWWSCGCILYEMLC

GQMPYKDMQANQIIRTVTELGERPPIPEDCPQHLAKLITKCWSQDPEDRPTMAKVVA----ELQDSKY
|. |.   | ..... .             .. .  .| ||.  |||.|||  .. .      ..   
GYPPFP--QMQMMFKKIG------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 91727.m00169.AA TyrKc 171-421 29 3.2e-65 223.91 SMART 1-280 (280) Show / Hide 
Range on Protein: 171-421
Range on HMM: 1-280/280
Sequence Identity: 29% (85 aa)

CVFEKTIGRGQSGTVYLGHFKDSDDNIAIKVLSKQTLSQADVESYRREVYFLTIL--SHPSLTKFCGYTED--------APFYICTEFMSGGSLYHKLRN
 ...|..|.|. |.||.|. |    . |.|.| . .     .|  .||   .. |  .|| . .. |.  .         | .| .|.|..|.| . ||.
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRK

NPEQLNPTTRSLIALTVARGLEYLHSKGVIHRDLKSLNVLLDDNNNAKICDFGMVRTRDSR-------PMT------GMI--GTVHWMAPEVLMSTPFYD
. ..|.. .   ... .|.| ||||||..|||||   |.|...|. .||.|||. |  ..         .       |      . |||||..  .  . 
HRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI-NYGKFT

ERVDVYSFGIFLWELLT-GQMPYKDM----QANQIIRTVTELGERPPIPED--------CPQHLAKLITKCWSQDPEDRPTMAKVVAEL
.  ||.|||. .||..| ||.|| .|      || ..   . |.|.|.|..        ||. . .....||  |||||||.. .. ..
TKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase 91727.m00169.AA TK 171-421 17 1.2e-62 208.5 In-house 1-486 (486) Show / Hide 
Range on Protein: 171-421
Range on HMM: 1-486/486
Sequence Identity: 17% (84 aa)

CVFEKTIGRGQSG---TVYLGHFKDSD-------------------------DNIAIKVLSKQ-TLSQADVES--------------YRREVYFLT--IL
 ...|..|.|| |   .||.|  .. .                            |.|.| .  . ||.. .                 .|   .   ..
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

SHPSLTKFCGYTEDA-------------PFYICTEFMSGGS----LYHKLRNNPE---------------------------------------------
 || . .. |.  .              |..| .|.|..|.    | . ||....                                             
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

------------------------------QLNPTTRSLIALTVARGLEYLHSK------GVIHRDLKSLNVLLDDNNN-----------AKICDFGMV-
                              ||.. ..  ... .|.|.||||||      ...||||   |.|...||.           .||.|||.  
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSR

-----RTRDSRPMTGMIGTVH------------------------------WMAPEVLMSTPF--------YDERVDVYSFGIFLWELLT-G-QMPYKDM
     ..||  . .    .                                |||||.|..  |        . .  ||.|||...||..| | ...| .|
QGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGM

QA---------NQIIRTVTEL-----------GERPPIP--EDCP--------------QHLAKLITKCWSQDPEDRPTMAKVVAEL
            .... ...            |.| . |  ..||              . .. |...||. |||||||.. .. .|
SNQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL
Kinase 91727.m00169.AA Dicty4-Unclassified 173-421 34 1.5e-60 206.06 In-house 3-263 (263) Show / Hide 
Range on Protein: 173-421
Range on HMM: 3-263/263
Sequence Identity: 34% (91 aa)

FEKTIGRGQSGTVYLGHFKDSDDNIAIKVLSKQTLSQA--DVESYRREVYFLTILSHPSLTKFCGYTEDAP------FYICTEFMSGGSLYHKLR-----
  . ||.|    |. |  |  |  .|.| .     .     .. ...||  |  ..|| | |  ||   .|      . | .|||  | |          
IDQFIGKGHFSKVHKGNWKGKD--VAVKKFNENKFKFREEMIQDFKKEVEILGSIQHPNLVKCYGYCI-NPRSHKSTMCIVMEFMHKGNLFEVIHSKPSE

-NNPEQLNPTTRSLIALTVARGLEYLHSKGVIHRDLKSLNVLLDDNNNAKICDFGMVRTRD-SRPMTGMIGTVHWMAPEVLMSTPFYDERVDVYSFGIFL
 . | .|. |    .|. .|.|. .||.. .||||.|| |.|.| ..|.|| |||. |  |    ||   ||. | .||.||    |  . ||||... |
QQQPIKLDDTLIIKYAFDIAQGMQHLHTRNFIHRDIKSSNILMDKHFNIKIADFGISRVIDFNFNMTTIAGTPKWESPECLMHES-YNQKSDVYSYAMML

WELLTGQMPYKDMQ-ANQIIRTVTELGERPPIPEDCPQHLAKLITKCWSQDPEDRPTMAKVVAEL
.||.||  || . |    . | | . . || ||. |.  . |||  ||. ||  |||| ...  |
YELATGDEPYQEIQSIMNAARSVCDKKLRPKIPDNCDNFWKKLIKWCWHNDPNKRPTMNQIIQYL
Kinase 91727.m00169.AA UTK 171-421 28 4.8e-57 193.69 In-house 1-296 (296) Show / Hide 
Range on Protein: 171-421
Range on HMM: 1-296/296
Sequence Identity: 28% (83 aa)

CVFEKTIGRGQSGTVYLGHFKD-----SDDNIAIKVLSKQTLSQADVE---SYRREVY---FLTILS-HPSLTKFCGY-TEDAPFYICTEFMSGGSLYHK
  . ...|.|. |.|....|..      ..  |.||...   .| . |     ..|     ..  .. ||.. .. |. | . |..| ||.|..|.| . 
VQLGRQLGQGAFGEVHKARFTQCSEHMYEMDVAVKVCQHHADAQQEPEPYPDFMEEARELQMMKQFHWHPNVLRLVGVCTQEEPWMIVTEYMENGDLRSY

LRNNPE-------QLNPTTRSLIALTVARGLEYLHSKGVIHRDLKSLNVLLDDN-------NNAKICDFG---MVRTRD---------SRPMTGMIG---
||....       .|. ..|   |. .|||..||||.|..||||   |.|....       . .||.|||   | |            . ..  . .   
LRRHRPTPPACPHWLTLHQRLCMAWDIARGMQYLHSCGFVHRDLAARNCLVHMHRMMWHCMMVCKIADFGRGGMSRRVNTFHFSNRYWESYYYMAQHQDR

-TVHWMAPEVLMSTPFYDERVDVYSFGIFLWELLT-GQMPYKDMQANQIIRTVTELG-ERPPIPEDCPQHLAKLITKCWSQDPEDRPTMAKVVAEL
 .. |||||.| .   . .  ||.|||...||..| |..||..| . |..  |.. |  |.| |.|||  . .| ..|| .||..||..  .|...
WPIRWMAPEALTHHTRFTTKSDVWSFGVVCWEIWTWGRLPYPGMSNMQVWHQVCNGGRYRMPCPWDCPHPVYRLMHRCWHYDPQERPDFEDLVQQM
Kinase 91727.m00169.AA STE 173-416 22 4.9e-57 195.79 In-house 1-350 (359) Show / Hide 
Range on Protein: 173-416
Range on HMM: 1-350/359
Sequence Identity: 22% (79 aa)

FEK--TIGRGQSGTVYLGHFK------DSDDN---------IAIKVLSKQTLSQ---------------ADVESYRREVYFLTILS--HPSLTKFCGYTE
.|.   ||.| .||||..  .      ... .         .|||...... ..                ..... .|. ..  ..  ||   |. |. .
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

DAP--------FYICTEFMSGGSLYHKLRNNPEQLNP-------------TTRSLIALTVARG-LEYLHSKGVIHRDLKSLNVLLDDNNNAKICDFGMVR
.           .|| |.|.||||   .... . ..|             .  . |.  . .| |.||||...||||.|. |.||     .|.||||   
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-----VKLCDFGVCG

-------------------TRDSRPMTGMIGTVHWMAPEVLMS-----TPFYDERVDVYSFGIFLWELLTGQMPY---KDMQANQIIR--TVTEL-----
                   |....  | ..||  ||||||..       . ||...|..|.|. ..|..||. |.   ..|.|   |   .. .      
QLTDSMANIQSNNIIDCIETMQQKRNT-FVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQL

----GERPPIPE-------------------DCPQHLAKLITKCWSQDPEDRPTMAK
    |. ||.|.                    . ...   | ||   ||..|||  .
CIVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQ