Gene LmjF32.1810 (L.major)

LmjF32.1810

Species: L.major
Alias: LmajK124, LmjF32.1810
External Links:
Annotation:

Classification

Group: Other
Family: NEK
Subfamily: NEK-Unclassified

Sequence

Name Sequence Type Origin Length Description Download
LmjF32.1810.AA Protein None 655 None Fasta, JSON
LmjF32.1810.kin_dom Protein Kinase Domain None 326 None Fasta, JSON

Protein domain

Protein domains of LmjF32.1810.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
S_TKc LmjF32.1810.AA S_TKc 144-469 22 2.5e-59 204.34 SMART 1-231 (231) Show / Hide 
Range on Protein: 144-469
Range on HMM: 1-231/231
Sequence Identity: 22% (74 aa)

YIKISSIGRGAYGEAYMVKRNPDYDAAARPMVEAQIQSNALANPTQPNGLYVAKVMDLRAMMSQDRQYAQTEIMCLAHTHHFAIIRYYEHYVLDSDDETV
| ..  ||.||.|. | .. .                          . ..  |...         . .. || .| . ||  |...|....     . .
YEILRKIGKGAFGKVYKCRHKK------------------------TGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQD----DHL

VIVTELADH--GDLRRNLYSGSVVRPFLEAGSQATTGGNAGTTNSGMLLTEREAGTYFVQLLLALHHISARRMIHRDIKSANVLLTSRGFLKLGDFGFSQ
 .|.|..|.  |||.. . .    ..                   .  ..| .|  |. |...|| ..  .. ||||.| .|.||..   .|..|||.. 
YMVMEYCDGDLGDLFDYIKKRGRHGL-------------------RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLAR

KYESTVSSETIAGTFLGTPYYLSPEMWKGKRYGK-KADVWAAGVVLYEMLMGGRRPFEAAGLPELRMCVLQEEFTPPTGPPTSGTADVNSQEGGQAKFSN
..           || |||.|..||.     ||| |.|.|. |..|||||  |. ||.    ... . ..                            | 
QL----------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLC-GYPPFP---QMQMMFKKIG---------------------------SP

DMRELLVAIFQKAPEKRPSAEELLH-------KPVM
......  ..|| |||||.| |.|.        | .
EAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase LmjF32.1810.AA NEK 193-416 30 2.5e-52 180.18 In-house 31-248 (286) Show / Hide 
Range on Protein: 193-416
Range on HMM: 31-248/286
Sequence Identity: 30% (74 aa)

LYVAKVMDLRAMMSQDRQYAQ-TEIMCLAHTHHFAIIRYYEHYVLDSDDETVVIVTELAD-HGDLRRNLYSGSVVRPFLEAGSQATTGGNAGTTNSGMLL
||| | ...  | ....| ||  |.  |.. .|  |..||.... . ....  || | ..  ||| . . |       .. . |           .| ..
LYVWKKINMGNMSEKEKQNAQNNEVRILKQLKHPNIVKYYDSFI-EEQNNCLCIVMEYCEGGGDLYQKIKS-------IKKQKQ-----------KGKYF

TEREAGTYFVQLLLALHHISAR-----RMIHRDIKSANVLLTSRG----FLKLGDFGFSQKYESTVSSETIAGT-FLGTPYYLSPEMWKGKRYGKKADVW
 |..   .|.|..|||...  |     . .|||||..|. ||...    ..|.|||| |   ..|..    | | . |||||.|||....| |. |.|.|
EEEQIWDWFIQMCLALKYMHDRKGPQRKILHRDIKPQNIFLTKNNNDYHNVKIGDFGISKVLNHTTD---MAYTTQVGTPYYMSPEVCQNKPYNNKSDIW

AAGVVLYEMLMGG-RRPFEAA--GLPELRMCVLQE-EFTP
. |.||||| .   ..||||    .|.| | . .. .. |
SLGCVLYEMCTLKPKHPFEAWDMNMPSLYMKIMKGPQYPP
Pkinase LmjF32.1810.AA Pkinase 144-469 20 1.3e-51 182.58 Pfam 1-293 (293) Show / Hide 
Range on Protein: 144-469
Range on HMM: 1-293/293
Sequence Identity: 20% (74 aa)

YIKISSIGRGAYGEAYMVKRNPDYDAAARPMVEAQIQSNALANPTQPNGLYVAKVMDLRAMMSQDRQYAQT--EIMCLAHTHHFAIIRYYEHYVLDSDDE
| ... ||.|..|. |  ..  . .                        ... |....|   |. .|..    ||  ... .|  |.|.|. .     . 
YHIGRKIGSGSFGCVYKCHHKGTGK------------------------IVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFED---KD

TVVIVTELADHG----DLR----RNLYSGSVVRPFLEAGSQATTGGNAGTTNSGMLL--TEREAGTYFVQLLLALHHISARRMIHRDIKSANVLLTSRGF
 . .|.|....|    ||     .                            ..  .  .|.|.  |. |.| .| .. ... ||||.|..|.|. ..| 
HIYMVMEYCEGGLYVMDLFDYIST---------------------------WRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGH

L----KLGDFGFSQKYESTVSSETIAGTFLGTPYYLSPEMWK-GKRYGKKADVWAAGVVLYEMLMGGRRPFEAA------GLPELRMCVLQ---------
.    |..|||.. ... . ...  . || |||.|..||  . |. ||.|.|.|..|..|||||  || ||  .         ..   ...         
IDACVKICDFGLAKQFD-Y-NNS--MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLC-GRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPW

-------EEFTPPTGPPTSGTADVNSQEGGQAKFSNDMRELLVAIFQKAPEKRPSAEELLHKPVM
       . |.. . .           .    . | ......  ...| |.|||.||..|. | .
WCSISYFF-FRH-W-H--------F-HWTF-HNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase LmjF32.1810.AA NEK1 298-469 33 3.3e-50 172.36 In-house 109-276 (276) Show / Hide 
Range on Protein: 298-469
Range on HMM: 109-276/276
Sequence Identity: 33% (63 aa)

YFVQLLLALHHISARRMIHRDIKSANVLLT--SRG---------------FLKLGDFGFSQKYESTVSSETIAGTFLGTPYYLSPEMWKGKRYGKKADVW
.|.|. ||| ||. |. .|||||| |. ||  . |               ..|||||| .    .|..    | | .|||||||||..  | |  | |.|
WFCQICLALNHIHDRKILHRDIKSQNIFLTISKNGMGSGSGSGSSNDSIPLVKLGDFGIARMLNHTME---YACTCIGTPYYLSPEICQNKPYNNKSDIW

AAGVVLYEMLMGGRRPFEAAGLPELRMCVLQEEFTPPTGPPTSGTADVNSQEGGQAKFSNDMRELLVAIFQKAPEKRPSAEELLHKPVM
..|.|||| |.   .||||. .. |.. ..|  ..|.                  . .|.. ..|.   |.. |. |||.  .| .| .
SLGCVLYE-LCTLKHPFEANNWKNLVLKICQGTYPPIP-----------------PHYSYELQSLVSQMFKRNPRHRPSVNQILERPFI
Kinase LmjF32.1810.AA NEK8 292-469 34 5e-49 138.04 In-house 118-278 (278) Show / Hide 
Range on Protein: 292-469
Range on HMM: 118-278/278
Sequence Identity: 34% (64 aa)

EREAGTYFVQLLLALHHISARRMIHRDIKSANVLLTSR-GFLKLGDFGFSQKYESTVSSETIAGT---FLGTPYYLSPEMWKGKRYGKKADVWAAGVVLY
|.. . ||.| ..|.||.      |||.| .|...| . ...|.|||| | .     .... . |    .|||||.|||| .|| |  | |.|| | |||
EQMILWYFFQMCSAVHHMHQHNILHRDLKTQNIFMTRHRMVVKIGDFGISKI----MNTKYHMQTTKTVVGTPYYMSPEMCEGKPYNQKSDMWALGCVLY

EMLMGGRRPFEAAGLPELRMCVLQ-EEFTPPTGPPTSGTADVNSQEGGQAKFSNDMRELLVAIFQKAPEKRPSAEELLHKPVM
||.   .| |||. ||.| .   |  ...|           . ..       ||.|| |  .  |. ||.|||| ...  |  
EMCC-LKRAFEASNLPALVWKIMQCRAYEP-----------ISDH------YSNEMRMLVHNCLQQDPEQRPSASQIMAMPLC
Kinase LmjF32.1810.AA CAMK 149-469 17 1.2e-41 131.48 In-house 1-425 (425) Show / Hide 
Range on Protein: 149-469
Range on HMM: 1-425/425
Sequence Identity: 17% (86 aa)

SIGRGAYGEAYMVKRNPDYDAAARPMVEAQIQSNALANPTQPNGL------------YVAKVMDLRAM--------------------------MSQDRQ
 .|||..|. .                        |.  .. .|.            . .|..| . .                            .||.
TLGRGSFGKVK------------------------LCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRK

YAQTEIMCLAH-------THHFAIIRYYEHYV------------LDSD-----DETVVIVT---ELADHGDL--R-------RNLYSGSVVRPFLEAGSQ
  . || .. .        .|  ||. ||.|               |.     |. ...|.   |... |.|  .       .  |. .       .   
NVRREIEIMKKLQGIGNKLDHPNIIKLYEVYEDPHYFKNTNDYET-SKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEF------D---

ATTGGNAGTTNSGML--------LTEREAGTYFVQLLLALHHISARRMIHRDIKSANVLLTSR-----------------GFLKLGDFGFSQKYESTVSS
                       .||||| .|| |.. |.|..  .  .|||.|  |.||...                 . .|. ||||..|...  ..
--------------QFDIVERGRFTEREARRYFRQICSAVHYCHSHNIVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENN

ETI--------------------AGTFLGTPYYLS-PEMWKGKR--------------YGKKADVWAAGVVLYEMLMGGRRPFEAA-------------G
 ..                      || |||.| . ||. .||.              ||.|.|.|..||.|| || | . ||..               
FMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNMQNATDEEKPYYGPKCDMWSCGVILYIMLCG-YPPFYGDCDNEICEDEWIGMN

LPELRMCVLQEEFTPPTGPPTSGTADVNSQEGGQAK---------------FSNDMRELLVAIFQKAPEKRPSAEELLHKPVM
..||   ... ... |  . .  ...         .               .| . . |.  . |. ||||...|. |  | |
DYELFEKIMKGKYDFPPPYFSPISCN---------YGPEWWDDISDEFHHFVSQECKDLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase LmjF32.1810.AA Ciliate-E2-Unclassified 144-469 22 2.1e-40 137.89 In-house 1-352 (352) Show / Hide 
Range on Protein: 144-469
Range on HMM: 1-352/352
Sequence Identity: 22% (87 aa)

YIKISSIGRGAYGEAYMVKR--NPDYDAAARPMVEAQIQSNALANPTQPNGLYVAKVMDLRAMMSQDRQYAQTEIMC--LAHTHHFAIIRYYEHYVLDSD
|..|  ||.|..|. |....  .  . .|   |  .||..  . .  . . .  .| |  . . ...| |    ||   | .  |  |......   . |
YKIIKQIGQGGFGKVYKCQHKKQK-QYYAMKYMKKIQIYKQKQIMNKD-EIMNEMKEMNNKKK-YHQRKY--NKIMQQILLNHPHPFIVKMFYC---FQD

DETVVIVTELADHGDLRRNLYSGSV---VRPFLEAGSQATTGGNAGTTNSGML----------LTEREAG-----TYFVQLLLALHHISAR-RMIHRDIK
.... ||.|....|||.  . . .    .                     | .          .||..|      .|| |.|..| ..      ||||||
KQNIYIVMEYCEGGDLWQYIKKRKKQKQK---------------------GNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIK

SANVLLTSRG---FLKLGDFGFSQKYEST------------VSSETIAGTFLGTPYYL----SPEMWKGKRYG----KKADVWAAGVVLYEMLMGGRRPF
  |.|... |    .|. |||.| ||..             . .. .. || |||.|.    .||. .|. |.    .|.|.|. ||.|||||.|  .||
PENILFDNNGKNYYIKIIDFGISKKYQQNNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGY-YPF

EAAGLPE----------------LRMCVLQEEFTPPTGPPTSGTADVNSQEGGQAKFSNDMRELLV----AIFQKAPEKRPSAEELLHKPVM
..    .                |.   .| ..  |  |. .             . |.   ...      ...| |.||...|..|  | .
YDNNCEQHQQLITQWINNAYRKQLYQNIKQKNIQFPKFPWQQ----------IPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase LmjF32.1810.AA Ciliate-E2 227-469 20 2.4e-39 132.7 In-house 94-365 (365) Show / Hide 
Range on Protein: 227-469
Range on HMM: 94-365/365
Sequence Identity: 20% (66 aa)

IIRYYEHYVLDSDDETVVIVTELADHGDLRR-----NLYSGSVVRPFLEAGSQATTGGNAGTTNSGMLLTEREAGTYFVQLLL---------------AL
||..||..  . ||... .|.|....|||.      .. ...                          .||.|..... |.|                ||
IIKMYECFQ-EKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIE-----------------K-D-KYFTEKEIKYIMKQILQGFKTKAEFYIACIILAL

HHISARR-MIHRDIKSANVLLTSRGFLKLGDFGFSQKY--------------ESTVSSETIAGTFL---------------GTPYYLSPEMWK-------
...  .   ||||||  |.|.     .|. |||.|.||              . .  .  . .|.                |||.|..||. .       
EYLHSKNNIIHRDIKPENILF-----IKIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQ

--GKRYGKKADVWAAGVVLYEMLMGGRRPFEAAGLPELRMCVLQEEFTPPTGPPTSGTADVNSQEGGQAKFS----------------------NDMREL
  .|.|..|.|.|..||.|||||.| ..||                               . .. .. .|.                      ...  |
QKQKGYDYKCDIWSLGVILYEMLFG-KPPF------------------------------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDL

LVA----IFQKAPEKRPS-AEELLHKPVM
.      ..|| ||||.. .|..|  | .
IKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase LmjF32.1810.AA STE 144-469 18 7.7e-39 134.8 In-house 1-359 (359) Show / Hide 
Range on Protein: 144-469
Range on HMM: 1-359/359
Sequence Identity: 18% (78 aa)

YIKISSIGRGAYGEAYMV---------------KRNPDYDAAARPMVEAQIQSNALANPTQPNGL------YVAKVMDLRAMMS---------------Q
. .|. ||.||.|. |                 .                                     .  |.|.|.   .               .
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVEN------------------------------NGETGEIMAIKQMNLENCNNKDENQENQELENKNHE

DRQYAQTEIMCLAHTH--HFAIIRYYEHYVLDS----DDETVVIVTELADHGDLR---RNLYSGSVVRPFLEAGSQATTGGNAGTTNSGMLLTEREAGTY
..|  . ||  . . .  |  |..|| .|. ..    .|... |. |. | | |.   .. |.     ..                  .  . | . ...
EMQQILKEIKIMKKCNHMHPNIVKYYGCYFKEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQ-------------H-QHRFPESQIAYI

FVQLLLA-LHHISARRMIHRDIKSANVLLTSRGFLKLGDFGFSQKYESTVS------------SET-IAGTFLGTPYYLSPEMWKG------KRYGKKAD
 .|.| . |...   . ||||||.||.||      || |||.. . .....            .      || ||| . .||. ..      | |. |.|
CRQILKGLLYYLHSHHIIHRDIKPANILL-----VKLCDFGVCGQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCD

VWAAGVVLYEMLMGGRRPF---EAA------------------------GLPELRMCVLQEEFTPPTGPPTSGTADVNSQEGG----QAKFSNDMRELLV
.|  | .. ||.  |. |.                              . | |   . |.|  ..          .  . |     . |.| .... . 
IWSLGCTIIEMA-TGKPPWHDMHPMRAMFMIPFNYHMQQQFEQLCIVNGPPPPLPDHLSQNEM-IS----------Y--G-GSGTTYPHKWSPEFKDFIN

AIFQKAPEKRPSAEELLH--KPVM
  .|| |.|||.|..||.   |  
KCLQKDPNKRPTASQLLKSEHPFI
Kinase LmjF32.1810.AA ULK 227-469 21 1e-33 115.09 In-house 80-329 (329) Show / Hide 
Range on Protein: 227-469
Range on HMM: 80-329/329
Sequence Identity: 21% (62 aa)

IIRYYEHYVLDSDDETVVIVTELADHGDLR----RN-------LYSGSVVRPFLEAGSQATTGGNAGTTNSGMLLTEREAGTYFVQLLLALHHISARRMI
|...|. .  . .   . |..|. ..|||.    .|       .                           .  |.| ||  .| |.| .. ..  .. |
IVKLYDWFETSNH-NNIYIIMEYCNGGDLEQYIKKNKKLPEDTE--------------------------EKKRLSEQEAIQFFKQILNGFKELHKHNII

HRDIKSANVLLTSR------------GFLKLGDFGFSQKYESTVSSETIAGTFL------GTPYYLSPEMWK----GKRYG-KKADVWAAGVVLYEMLMG
||||| .|.|..              | ||..||||... ..   .. .. |..      |||.| .|. ..    .| |. .|.|.|  |...||||  
HRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNDNMEQQMMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLY-

GRRPFEAAGLPELR---MCVL-QEEFTPPTGPPTSGTADVNSQEGG------QAKFSNDMRELLVAIFQKAPEKRPSAEELLHKPVM
|. ||.|    ..    .  | . ....|.         ...|         . ..|.....|.   .|. ...| | |||.. |..
GKPPFYAW-FNDQYLQIIQKLINNPPPWPQ--------QIKKQPLQFPKDGNDPQISPECKDLIRRMLQYDEKDRISWEELFNHPWF
Kinase LmjF32.1810.AA ULK 290-392 30 1.1e-32 113.38 In-house 123-248 (324) Show / Hide 
Range on Protein: 290-392
Range on HMM: 123-248/324
Sequence Identity: 30% (38 aa)

LTEREAGTYFVQLLLALHHISARRMIHRDIKSANVLLTSR------------GFLKLGDFGFSQKYESTVSSETIAGTFL------GTPYYLSPEMWK--
|.| ||  .| |.. .. ..  .  |||||| .| |..              | ||..||||... ..   ....  |..      |||.| .|. ..  
LSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNNNMEQQMCQTCVNEKRIKGTPLYMAPQILQGQ

--GKRYG-KKADVWAAGVVLYEMLMG
  .| |. .|.|.|  |...|||| |
GEQKPYYDYKCDIWSLGCIFYEMLYG
Kinase LmjF32.1810.AA STE20 301-392 35 2e-26 93.76 In-house 125-223 (288) Show / Hide 
Range on Protein: 301-392
Range on HMM: 125-223/288
Sequence Identity: 35% (36 aa)

QLLLALHHISARRMIHRDIKSANVLLTSRGFLKLGDFGFSQKYES--TVSSETIA---GTFLGTPYYLSPEMWKG-----KRYGKKADVWAAGVVLYEML
..| .|... ....||||||..|.|||..|  || |||.... ..  .    |..    || ||||...||. ..     | |. |.|.|. |  . ||.
EVLQGLDYLHSNHIIHRDIKADNILLTEDGEVKLADFGVCAQLTKHGR-D--TMQFKRNTFVGTPYWMAPEVIQCMEGPDKGYDYKCDIWSLGITAIEMA

MG
 |
EG
Kinase LmjF32.1810.AA TyrKc 144-467 18 4.7e-15 20.68 SMART 1-280 (280) Show / Hide 
Range on Protein: 144-467
Range on HMM: 1-280/280
Sequence Identity: 18% (65 aa)

YIKISSIGRGAYGEAYMVKRNPDYDAAARPMVEAQIQSNALANPTQPNGLYVA-KVMDLRAMMSQDRQYAQTEIMCLAHT--HHFAIIRYYEHYVLDS--
  ..  .|.||.|| |  . .                            . || |..   |     |.    |.  . .   ||  |.| |  .....  
ITLGKKLGEGAFGEVYKGTWK----------------------------IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLY-GVCTQQGR

---DDETVVIVTELADHGDLRRNL-YSGSVVRPFLEAGSQATTGGNAGTTNSGMLLTEREAGTYFVQLLLALHHISARRMIHRDIKSANVLLTSRGFLKL
    .| . ||.|...||||.  | ...                           |. ..   . .|      ... .. ||||.   |.|.....  | 
NFMYIEPLMIVMEYMPHGDLKDYLRKHRPK-------------------------LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKI

GDFGFSQKYEST----VSSETIA------GTFLGTPYYLSPEMWKGKRYGKKADVWAAGVVLYEMLMGGRRPFEA-----AGLPELRMCVLQEEFTPPTG
.||| | . ..     .|....       | ..     ..|| .. ...  | |||. ||...|..  |  | .          |.. .| | .  |.  
SDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQ--

PPT----SGTADVNSQEGGQAKFSNDMRELLVAIFQKAPEKRPSAEELLHKP
||     |      .        . .| ..     .  ||.||. .|. .. 
PPNDYPMS------F-----VCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase LmjF32.1810.AA NEK 437-469 34 6.5e-07 20.82 In-house 252-286 (286) Show / Hide 
Range on Protein: 437-469
Range on HMM: 252-286/286
Sequence Identity: 34% (12 aa)

K--FSNDMRELLVAIFQKAPEKRPSAEELLHKPVM
.  .|.|...|.   .|| ||.|||....| .| .
HRMYSQDLQNLISQMLQKDPEQRPSCNQILEMPFI
Kinase LmjF32.1810.AA Pkinase_Tyr 245-338 23 2e-06 22.24 Pfam 84-156 (270) Show / Hide 
Range on Protein: 245-338
Range on HMM: 84-156/270
Sequence Identity: 23% (22 aa)

IVTELADHGDLRRNLYSGSVVRPFLEAGSQATTGGNAGTTNSGMLLTEREAGTYFVQLLLALHHISARRMIHRDIKSANVLLTSRGFLKLGDFG
||.|.. ||||.  | . .                     ...  ||  .   . .|   .. . .....||||.   |.|.|. .. | .|||
IVMEYMPHGDLLDYLRKHR---------------------EDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFG
Kinase LmjF32.1810.AA NEK 144-166 43 1.4e-05 16.01 In-house 1-23 (286) Show / Hide 
Range on Protein: 144-166
Range on HMM: 1-23/286
Sequence Identity: 43% (10 aa)

YIKISSIGRGAYGEAYMVKRNPD
| .|  ||.|..|..| |.|  |
YEIIKKIGQGSFGKVYKVRRKSD
Kinase LmjF32.1810.AA STE20 410-469 23 3.8e-05 15.08 In-house 249-288 (288) Show / Hide 
Range on Protein: 410-469
Range on HMM: 249-288/288
Sequence Identity: 23% (14 aa)

LQEEFTPPTGPPTSGTADVNSQEGGQAKFSNDMRELLVAIFQKAPEKRPSAEELLHKPVM
|... .                   . |.| . ....    || |||||.|..||. |  
LKDD-K-------------------PHKWSPEFHDFVDKCLQKDPEKRPTASQLLKHPFI
Kinase LmjF32.1810.AA NEK1 144-163 45 5.2e-05 13.52 In-house 1-20 (276) Show / Hide 
Range on Protein: 144-163
Range on HMM: 1-20/276
Sequence Identity: 45% (9 aa)

YIKISSIGRGAYGEAYMVKR
|..|. || |..| |. ||.
YHYIKQIGEGSFGKAWLVKH
Kinase LmjF32.1810.AA Pkinase_Tyr 363-398 29 0.000409 14.56 Pfam 181-217 (270) Show / Hide 
Range on Protein: 363-398
Range on HMM: 181-217/270
Sequence Identity: 29% (11 aa)

LSPEMWKGKRYGKKADVWAAGVVLYEMLMGGRRP-FE
..|| .. ...  | |||. ||...|..  |. | ..
MAPECINYGKFTTKSDVWSFGVLMWEIFTYGEQPTYP
Kinase LmjF32.1810.AA NEK8 144-158 46 0.001199 6.15 In-house 1-15 (278) Show / Hide 
Range on Protein: 144-158
Range on HMM: 1-15/278
Sequence Identity: 46% (7 aa)

YIKISSIGRGAYGEA
|..|  .|||| |..
YERIRVVGRGAFGIC
Kinase LmjF32.1810.AA NEK8 195-233 38 0.001582 5.8 In-house 30-68 (278) Show / Hide 
Range on Protein: 195-233
Range on HMM: 30-68/278
Sequence Identity: 38% (15 aa)

VAKVMDLRAMMSQDRQYAQTEIMCLAHTHHFAIIRYYEH
. |  ..  | .  || || ||  |.  .|  || ||.|
IWKQINMHRMSEKERQMAQNEIQVLSMLQHPNIISYYDH
Kinase LmjF32.1810.AA ULK 437-469 27 0.004418 6.85 In-house 292-324 (324) Show / Hide 
Range on Protein: 437-469
Range on HMM: 292-324/324
Sequence Identity: 27% (9 aa)

KFSNDMRELLVAIFQKAPEKRPSAEELLHKPVM
|.|.....|.   .|. ...| | ||... |..
KISPECKDLIRRMLQYDEKDRISWEEIFNHPWF
Kinase LmjF32.1810.AA STE20 144-157 42 0.144949 1.85 In-house 1-14 (288) Show / Hide 
Range on Protein: 144-157
Range on HMM: 1-14/288
Sequence Identity: 42% (6 aa)

YIKISSIGRGAYGE
| ..  ||.|.||.
YELLEKIGQGSYGK
Kinase LmjF32.1810.AA STE20 197-241 28 0.201622 1.32 In-house 34-82 (288) Show / Hide 
Range on Protein: 197-241
Range on HMM: 34-82/288
Sequence Identity: 28% (14 aa)

KVMDLRAMMS--QDRQYAQTEIMCLAHTHHFAIIRYYEHYVLDSD--DE
|.|.|.  .   ....  |.||  ..  .|  |..||. |. |..  ||
KKMNLEKCDNEQDEWEDIQKEISIMKQCKHPNIVKYYGSYLKDDTCDDE
Kinase LmjF32.1810.AA ULK 144-159 31 0.21249 0.75 In-house 1-16 (329) Show / Hide 
Range on Protein: 144-159
Range on HMM: 1-16/329
Sequence Identity: 31% (5 aa)

YIKISSIGRGAYGEAY
|...  .| |..|  |
YCLNHCLGKGSFGKVY
Kinase LmjF32.1810.AA ULK 144-159 29 0.252559 0.53 In-house 1-17 (324) Show / Hide 
Range on Protein: 144-159
Range on HMM: 1-17/324
Sequence Identity: 29% (5 aa)

YIKISSIGRGAYG-EAY
|...  .| |..|   |
YCLNHCLGKGSFGVKVY
PH LmjF32.1810.AA PH 538-655 20 6.8e-11 43.44 SMART 1-82 (82) Show / Hide 
Range on Protein: 538-655
Range on HMM: 1-82/82
Sequence Identity: 20% (24 aa)

TCFEGVVYKNNHNGVWKERYLLLDGTTLTISLSKGKEAVGGGERSKRVLLSSIKSVSPCEVEDVHVRVVNAESPSDGYKPPYAFAIAMLSSNSIIFGVAS
.  || .||   .  ||.|.. |.. .|..  .|        . .... ||.. .|.. .                      .| | . .  ...|   |
VIKEGWLYKKS-K-RWKKRWFVLFNDCLYYYKDK--------KPKGSIPLSDC-TVRE-P----------------------CFEIHH-DR-TYYFQCES

AEELDHWMQALMRALQID
.||.. ||||. .|..  
EEEMQEWMQAIQKAIHNN
PH LmjF32.1810.AA PH 538-653 20 5.3e-09 35.12 Pfam 1-92 (92) Show / Hide 
Range on Protein: 538-653
Range on HMM: 1-92/92
Sequence Identity: 20% (24 aa)

TCFEGVVYKNNHNGVWKERYLLLDGTTLTISLSKGKEAVGGGERSKRVLLSSIKSVSPCEVEDVHVRVVNAESPSDGYKPPYAFAIAMLSSNSIIFGVAS
   || ..|   .. ||.|.. | ...| .  ...       .  . . ||.. .| ...                  | |. | | . . ....|  .|
VIKEGWLHKKGKRKSWKKRWFVLFNNCLYYYKDDK------YRPKGSIPLSDC-QVTKVPDN----------------KRPHCFQIRT-DRRTYYFQAES

AEELDHWMQALMRALQ
.||...||||. .|. 
EEEMNDWMQAIQSACR