Gene MLKz_a-2 (S.moellendorffii)

MLKz_a-2

Species: S.moellendorffii
Alias: MLKz_a-2
External Links:
Annotation:

Classification

Group: TKL
Family: MLK
Subfamily: MLKz

Sequence

Name Sequence Type Origin Length Description Download
MLKz_a-2.AA Protein None 568 None Fasta, JSON
MLKz_a-2.NA RNA None 1707 None Fasta, JSON
MLKz_a-2.kin_dom Protein Kinase Domain None 249 None Fasta, JSON

Protein domain

Protein domains of MLKz_a-2.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase MLKz_a-2.AA Dicty4 314-552 40 8.5e-96 319.94 In-house 13-277 (277) Show / Hide 
Range on Protein: 314-552
Range on HMM: 13-277/277
Sequence Identity: 40% (107 aa)

GDIYRGTFCGQDVAIKVI--KPETW-TEHLQEFVHEIAIMRKVRHKNIVQFIGACT----TPPDLCIVTEYMSGGTVHDYLQK------QKGNLHLYVLL
|  |.||  |..||.|.   . ..   . |.|| .|..|| | || ||..| ||||    .|...|||||||. |...  | .      |.  | .   .
GEVYKGTWRGKEVAVKKLNNHNQNFDENMLNEFRKEVHIMCKIRHPNICLFMGACTAPRSHPGKMCIVTEYMPKGNLYSLLHDKPSEQQQSIKLDWPLIK

R---IALDIAKGMDYLHQ-N-NIIHRDLKASSLLMDENGVVKVADFGVAR----IQDQDGIMTAETGTYRWMAPEVLGHSHYDQKADVFSFGVLLWELLT
|   .|.|.|.|| .||  | .|||||||.. ||.|.| .|||.||| ..    . |.   ...  ||  ||||||. |  |..||||.||| .|||.||
RAMRMAFDAARGMNWLHCCNPVIIHRDLKSHNLLVDKNWRVKVCDFGLSQYMKKHEDHKDNQMTACGTPCWMAPEVMMHQPYNEKADVYSFGIVLWEILT

KKVPYE--LMTPFQVAVGVLQEELRPTIPQDAHPKFSQLLEWCWRTNPADRPDFSEITLV--LKD
.. ||    | ..|.. .| .. ||| ||..  |....|..||| ..|  || |.||.    |  
RQEPYQKHHMPYMQFVRAVCNKKLRPPIPDWCPPSWKHLIQWCWDHDPQHRPSFEEIIQRRILEH
Kinase MLKz_a-2.AA TKL 314-550 29 2.1e-91 309.96 In-house 7-364 (364) Show / Hide 
Range on Protein: 314-550
Range on HMM: 7-364/364
Sequence Identity: 29% (108 aa)

GDIYRGTFCG----------QDVAIKVIKP---ETWTEHL-----------------------QEFVHEIAIMRKVRHKNIVQFIGACTTPPD-------
| .|.|.. |          .|||.|..|      .|...                       .... || .|.. || |||||.|.|. ||.       
GEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCGCVCMHP

------LCIVTEYMSGGTVHDYLQKQKGNLHLYVLLRIALDIAKGMDYLHQNN--------IIHRDLKASSLLMDENGV--------------VKVADFG
      ||||.||..||. ..||.       . ...|.|||||.||.|||..|        ||||||| . .| |||.               .|..|||
VGPWGQLCIVMEYCPGGSLLHYLH-------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWCCKICDFG

VARIQDQDGIMTA--------------------ETGTYRWMAPEVL----------------GHSHYDQKADVFSFGVLLWELLTKKVPYE--LMTPFQV
 .|  .|.| |..                    . ||.||||||||                ... |..|.||.|||..|||.|| ..||.   . | ..
LSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPYYDYPYMPMIF

A-------VGVLQEELRPTIP------------QDAHPKFSQLLEWCWRTNPADRPDFSEITLVL
.       ..| .. |||.||             |. | ...|...|| ..| .|| |.||.  |
QDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
Kinase MLKz_a-2.AA MLK 302-550 32 3.5e-91 309.22 In-house 1-291 (291) Show / Hide 
Range on Protein: 302-550
Range on HMM: 1-291/291
Sequence Identity: 32% (95 aa)

LKRIKKILPSSNGDIYRGTFCGQD-----VAIKVIKPET-----WTEHLQEFVHEIAIMRKVRHKN----IVQFIGACTTPPD-LCIVTEYMSGGTVHDY
..  ..|  .| |. ..|.. ..|     ||.| .. ..       .  ..|  |. . |...|.|    |.|| |.|. ||  .|||.||..||  ...
IQFHEWIGSGSFGKVWKGRWRNKDIVAKIVAVKRVRARIFDKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQPPCHFCIVMEYCEGGSLYNV

L--QKQKGN-----------LHLYVLLRIALDIAKGMDYLHQNN---IIHRDLKASSLLMDE------NGVVKVADFGVAR-IQDQDGI-MTAETGTYRW
|  .. |..             . .....||..|.||.|||..    ||||||| . .| ||      .|..|..|||..| ... .   |.   |||.|
LHGARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHSMAPKPIIHRDLKSHNILIDEICHDMHHGTLKICDFGTSRDWHQMC-TNMMSNAGTYAW

MAPEVL---GHSHYDQKADVFSFGVLLWELLTKKVPYE-LMTPFQVAVGVLQEELRPTIPQDAHPKFSQLLEWCWRTNPADRPDFSEITLVL
|||||.    .. |. |.||.|.||.|||.||..|||.  . |...| .| ...|||.||... . ...|.. || ..|..||.|..|   |
MAPEVIQQFRCEKYSEKCDVWSWGVVLWEMLTREVPYKQHYDPMAIAWWVAYNGLRPPIPSTCPEHWKKLMKQCWNQDPHKRPSFRQIVQHL
Kinase MLKz_a-2.AA TKL-Unique 304-550 35 8.3e-91 307.99 In-house 1-290 (290) Show / Hide 
Range on Protein: 304-550
Range on HMM: 1-290/290
Sequence Identity: 35% (104 aa)

RIKKILPSSNGDIYRGTFCGQDVAIKVIKP-ETWT-EHLQEFVHEIAIMRKVR-HKNIVQFIGACT----TPPDLCIVTEYMSGGTVHDYLQ--------
 ..||  .. | .|.|.. | .||||...| |    | .|||  |. .| | . |.|||...|.|.    .||..|||.||..||. .|.|.        
FWNKIGEGGYGQVYKGKWRGYPVAIKQFHPNEDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNNNNNN

-KQKGNLHLYVLLRIALDIAKGMDYLHQNN--IIHRDLKASSLLMDEN-----GVVKVADFGVARIQDQDGIMTAE----------TGTYRWMAPEVLGH
 ... .| . . ...|.|||.||.||| ..  ||||||| |..| |.|       .|..||| .......  ||.            |..||||||||  
NNNNCKLNMQQRVKMAIDIAQGMYYLHHCEPPIIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFRWMAPEVLRM

--SHYDQKADVFSFGVLLWELLTKKV------PYELMTPFQVAVGVLQ--EELRPTIPQDAHPKFSQLLEWCWRTNPADRPDFSEITLVL
  ..|..|.||.|||. |||..| |.      ||. |.. |..  | .  |..||.||..  . .. |.. ||. .| .|| |.||   |
NFCQYSEKSDVYSFGIVLWEIATRKITKTYKKPYQGMDQEQWCEMVHYMEENYRPPIPNHCPKEYRDLIQQCWHHDPSQRPSFDEIIHRL
Kinase MLKz_a-2.AA DRK 314-552 41 1.9e-83 282.49 In-house 13-258 (258) Show / Hide 
Range on Protein: 314-552
Range on HMM: 13-258/258
Sequence Identity: 41% (102 aa)

GDIYRGTFCGQDVAIKVIKPETWT--EHLQEFVHEIAIMRKVRHKNIVQFIGACTTPPDLCIVTEYMSGGTVHDYLQKQKGNLHLYVLLRIALDIAKGMD
|...|||  |  ||.|  .       . |.||  || .| . || ||.||.|.|. ||| ||..|||. |     |  ..  .    ......|.|||| 
GEVFRGTWRGTQVAVKMLFNHNINDENFLNEFHREINLMCQLRHPNICQFMGTCNNPPDICICMEYMPRGSLYNILHDESIEMDWPLMKQMMFDCAKGMI

YLHQNN--IIHRDLKASSLLMDENGVVKVADFGVAR----IQDQDGIMTAETGTYRWMAPEVLGHSHYDQKADVFSFGVLLWELLTKKVPYELMTPFQVA
|||  |  |||||||   || ||.  ||||||| .     ....   ||.  ||  | |||||    |  ||||.||.. |||..| . ||  | .||| 
YLHCCNPIIIHRDLKSHNLLVDEHWQVKVADFGLSTRFKKHKQHKFAMTM-CGTPCWTAPEVLRNQRYTEKADVYSFAIVLWECVTRQDPYFGMPTFQVV

VGVLQEELRPTIPQDAHPKFSQLLEWCWRTNPADRPDFSEITLVLKD
  | .. .|| .||   ||. ||.  || ..|  || . |.   |  
FSVGRHGMRPPMPQWCPPKYIQLMNDCWNEDPQHRPSMQECLERLEA
Kinase MLKz_a-2.AA TyrKc 302-550 32 7.9e-77 262.46 SMART 1-280 (280) Show / Hide 
Range on Protein: 302-550
Range on HMM: 1-280/280
Sequence Identity: 32% (93 aa)

LKRIKKILPSSNGDIYRGTFCGQDVAIKVIKPETWTEHLQEFVHEIAIMRKV--RHKNIVQFIGACTTP-------PDLCIVTEYMSGGTVHDYLQKQKG
.. .||.     | .|.||   ..||.|..|...    ...| .|. ||.|.  .|.|||...|.||..       . |.||.|||..|  .|||.| ..
ITLGKKLGEGAFGEVYKGTWK-IQVAVKMLKEDA----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRP

NLHLYVLLRIALDIAKGMDYLHQNNIIHRDLKASSLLMDENGVVKVADFGVARIQDQD-------GIMTA-----ET--GTYRWMAPEVLGHSHYDQKAD
.| .  || ....||.||.|||..|.||||| |   | .||..||..||| .|  . |          ..     .     .||||||.. .. .  | |
KLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTTKSD

VFSFGVLLWELLTK-KVPYELM----TPFQVAVGVLQEELRPTIPQD--------AHPKFSQLLEWCWRTNPADRPDFSEITLVL
|.||||..||..|  . ||. |     . | ..  ...  |. .|..        ....  |. ..||. .|.||| ||||   .
VWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase MLKz_a-2.AA Pkinase_Tyr 314-550 37 8.9e-76 257.27 Pfam 13-270 (270) Show / Hide 
Range on Protein: 314-550
Range on HMM: 13-270/270
Sequence Identity: 37% (96 aa)

GDIYRGTFC------GQDVAIKVIKPETWTEH--LQEFVHEIAIMRKV-RHKNIVQFIGACT--TPP-DLCIVTEYMSGGTVHDYLQKQ---KGNLHLYV
|..|.||        ...||.|..|. .  |.  ...| .|..||..  .|.|||...|.||    |  ..||.||| .|  .|||.|.   |..| .  
GEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRKHREDKQPLTMKD

LLRIALDIAKGMDYLHQNNIIHRDLKASSLLMDENGVVKVADFGVARIQDQDGIM-TAETGTY---RWMAPEVLGHSHYDQKADVFSFGVLLWELLT-KK
|| ....|||||.||...|.||||| |   | .||.|||..||| ||    |.   .. .|.    .|||||.. .. .  | || |||||.||..|  .
LLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECINYGKFTTKSDVWSFGVLMWEIFTYGE

VP-YELMTPFQVAVGVLQEELRPTIPQDAHPKFSQLLEWCWRTNPADRPDFSEITLVL
 | |. |....|   . ..  |  .|......  .|.  ||. .|.||| ||||   |
QPTYPGMSNEEVYEYIYEDGYRMPCPENCPDEIYDLMKQCWHYDPEDRPTFSEIHEQL
Kinase MLKz_a-2.AA LRRK 314-552 28 1.4e-72 247.46 In-house 13-351 (351) Show / Hide 
Range on Protein: 314-552
Range on HMM: 13-351/351
Sequence Identity: 28% (96 aa)

G-DIYRGTFCG----------------------------QDVAIKVIKPE---------------------------------TWTEHLQEFVHEIAIMR
|  .||... |                            |.||||... .                                   .. ..|| ||..||.
GTFVYRAKWRGQPVHVCRMHQKMLQPYMYQGARNSYDMCQWVAIKKWNRDPMTIDNDCNNSNNNNNLNNNNSEQVEDMDQNHEDCCRAFREFRHEVWIMS

KVRHKNIVQFIGACTTPPDLCIVTEYMSGGTVHDYLQKQKGN--------LHLYVLLRIALDIAKGMDYLHQNN--IIHRDLKASSLLM---D-------
. .| |||. .| |  |  ||.|.||.. |. ...|.. | .        .   ..|.|||.|||||.||| .|  |||||||    |.   .       
HLNHPNIVSLKGFCIHP--LCMVMEYAPHGDLYHFLHNKKQDGFHFMKAHISWMLKLKIALQIAKGMEYLHSHNPPIIHRDLKSPNILLWSSPQNHSPNY

--ENGVVKVADFGVAR--IQDQDGIMTAETGTYRWMAPEVLG---HSHYDQKADVFSFGVLLWELLTKK-VPYELMT-P-----FQVAVGVLQEELRPTI
  .. ..|.||||  |    .. |.    .|. .|||||...    . |..|.|..|||..|||||| .  |.. .. .             .| |||||
PNAHVCAKIADFGISRMFQCFHMGVAKGCVGNPGWMAPEIMRYNGEEEYTEKVDCYSFGMILWELLTRQHHPFDEHDFFDHMQWMEQIEDKIIEGLRPTI

PQD-AHP-----KFSQLLEWCWRTNPADRPDFSEITLVLKD
||.  .|      ...|...|| ..| .|| ||.|. .|..
PQHYCPPCQPWHMYQDLIQHCWQHDPKKRPHFSQIVKRLSQ
Kinase MLKz_a-2.AA TK 302-550 18 5.1e-72 240.49 In-house 1-486 (486) Show / Hide 
Range on Protein: 302-550
Range on HMM: 1-486/486
Sequence Identity: 18% (91 aa)

LKRIKKILPSSNG---DIYRGTFCG---------------------------QDVAIKVIKPETWTEHLQ----------------EFVHEIAIMR--KV
.. .||.     |   ..|.|.  |                           ..||.|..|... ..  .                |...|...|.  . 
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

RHKNIVQFIGACTTP------------PDLCIVTEYMSGGT----VHDYLQKQKG---------------------------------------------
.|.|||...|.|| .            . ..||.|||..|      .|||.| ..                                             
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

----------NLHLYVLLR-------------------IALDIAKGMDYLHQN------NIIHRDLKASSLLMDENGV-----------VKVADFG----
           |..  ||.                   ....||.|| |||..      |..|||| |   | .||.|           .|.||||    
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLLMCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSRQ

----VARIQDQDGIMTAETGTYR---------------------------WMAPEVLGHSH---------YDQKADVFSFGVLLWELLT--KKVPYELMT
     ||  ..|.  .. .. ..                           |||||.| . .         .  | ||.|||||.||..|  .. .|. |.
GSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGMS

P--------FQVAVGVLQEE--------------LRPTIPQDAH--------------PKFSQLLEWCWRTNPADRPDFSEITLVL
          |  .  |...              .|.  |....              . . .|.  ||. .|.|||.||..   |
NQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL
Kinase MLKz_a-2.AA LISK 314-550 34 2e-70 227.98 In-house 8-296 (296) Show / Hide 
Range on Protein: 314-550
Range on HMM: 8-296/296
Sequence Identity: 34% (101 aa)

GDIYRGTFC--GQDVAIKVIKPE----TWTEHLQEFVHEIAIMRKVRHKNIVQFIGACTT-PPDLCIVTEYMSGGTVHDYLQK---QKGNLHLYVLLRIA
| .|.||    ||..||| |.       . | .  .  |...|.. ||.|||||.|.|      | |||||..||..|.|| .   .| .|   . ..||
GKVYKGTHRQTGQVMAIKMIHRQPNDPNDPEYQKFMLREVQMMKNLRHPNIVQFMGVCYHNDGQLHIVTEYINGGDLHQYLKDMDKHKIPLPWPQRVKIA

LDIAKGMDYLHQNNIIHRDLKASSLLMDEN----GVVKVADFGVARIQDQDG-----------------------------IMTAET------GTYRWMA
||||.|| ||| .||||||||.  .| .||      .||.||| ||. |..                               |  .       ||  |||
LDIACGMSYLHSMNIIHRDLKSKNCLVRENDNNQWRIKVCDFGFARMMDCENNSPCNMPREDESDPCMDNDMPMKRKIPKKCMNQRKRRMTICGTPYWMA

PEVLGHSHYDQKADVFSFGVLLWELLTKKVPYE-LMTPFQ-VAVGVLQEELRPTIPQD-AHPKFSQLLEWCWRTNPADRPDFSEITLVL
||.|  . ||...||||||..| |. | . . . .. ...  . |. .||... |. |   | |..|  .| . .| .|| |.||. .|
PEMLLGQSYDESCDVFSFGIVLCEIITRVKADPDYWPRTPQHDFGLDYEEFWQKICPDDCPPPFLDLCFDCCKYDPKNRPSFKEIVQWL
Kinase MLKz_a-2.AA Dicty5 304-554 37 2.2e-70 240.15 In-house 2-260 (260) Show / Hide 
Range on Protein: 304-554
Range on HMM: 2-260/260
Sequence Identity: 37% (97 aa)

RIKKILPS-SNGDIYRGTFCGQDVAIKVIKPET-WTEHLQEFVHEIAIMRKVR--HKNIVQFIGACTTPPDL-CIVTEYMSGGTVHDYLQKQKG----NL
 . ..  | . | .| | . | ||||||  .|      ..||  |..||  .   | |.. . || .       .|||| . |.. .||  |.     ..
SFHDWIASGASGRVYNGIYKGMDVAIKVYSQENCMCFDWNEFYREVTIMSIFQSDHPNFIRCYGAHQYNDKYPFHVTEYCHNGSLFNYLNDQRKTTGQPI

HLYVLLRIALDIAKGMDYLHQNNIIHRDLKASSLLMDENGVVKVADFGVARIQDQDGIMTAETGTYRWMAPEVLGHSHYDQKADVFSFGVLLWELLTKKV
     | .|.|||..| .||  ||||||||    |  ||  .|. |||. |  |    || . ||  |||.|.     |.||.||.|||. |||..|.| 
AYFQQLHMAIDIAQSMRHLHSMNIIHRDLKSMNFLITENWKIKIIDFGTSRFVDNRYHMTMHVGTQCWMACELFNGQPYHQKCDVYSFGIVLWEMFTRKE

PYELMTPFQVAVGVLQEELRPTIPQDAHPKFSQLLEWCWRTNPADRPDFSEITLVLKDIM
||. ..    .| |   | ||||| |    .| | . ||   |  || | ||  ... |.
PYDNINNWNIPVMVMKGE-RPTIPKDCPTEISNLIKKCWQQKPHNRPSFKEICKYFESII
Kinase MLKz_a-2.AA Dicty4-Unclassified 302-550 32 2.2e-67 229.85 In-house 1-263 (263) Show / Hide 
Range on Protein: 302-550
Range on HMM: 1-263/263
Sequence Identity: 32% (87 aa)

LKRIKKILPSSNGDIYRGTFCGQDVAIKVIKPETWTEH---LQEFVHEIAIMRKVRHKNIVQFIGACTTP----PDLCIVTEYMSGGTVHDYLQ-----K
..  . |       ...|   | |||.| .           .|.|  |..|.  . | | |.  |.|  |      .|||.| |  |.           .
IQIDQFIGKGHFSKVHKGNWKGKDVAVKKFNENKFKFREEMIQDFKKEVEILGSIQHPNLVKCYGYCINPRSHKSTMCIVMEFMHKGNLFEVIHSKPSEQ

QKGNLHLYV--LLRIALDIAKGMDYLHQNNIIHRDLKASSLLMDENGVVKVADFGVARIQDQDGIMTAETGTYRWMAPEVLGHSHYDQKADVFSFGVLLW
|.  . |     ...|.|||.|| .||  |.||||.|.| .||| .  .|.||||..|  |    ||.  || .| .||.| |  | ||.||.|....|.
QQ-PIKLDDTLIIKYAFDIAQGMQHLHTRNFIHRDIKSSNILMDKHFNIKIADFGISRVIDFNFNMTTIAGTPKWESPECLMHESYNQKSDVYSYAMMLY

ELLTKKVPYELMT-PFQVAVGVLQEELRPTIPQDAHPKFSQLLEWCWRTNPADRPDFSEITLVL
||.|   ||     .  .|  |    ||| ||    . ...|  |||   |  || . .|.  |
ELATGDEPYQEIQSIMNAARSVCDKKLRPKIPDNCDNFWKKLIKWCWHNDPNKRPTMNQIIQYL
Kinase MLKz_a-2.AA Pkinase 326-546 26 4.3e-67 234.01 Pfam 27-287 (293) Show / Hide 
Range on Protein: 326-546
Range on HMM: 27-287/293
Sequence Identity: 26% (69 aa)

VAIKVIKPETWTE-HLQEFVH--EIAIMRKVRHKNIVQFIGACTTPPDLCIVTEYMSGG----TVHDYLQ-KQKGNL--HLYVLLRIALDIAKGMDYLHQ
||.|.|| ..  .  .|. ..  ||.||....|.|||..............|.||. ||      .||.. ...|..     .. .... |..|..|.|.
VAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRHGCFYFSEWECKFYMYQILRGLEYCHS

NNIIHRDLKASSLLMDENGVV----KVADFGVARI--QDQDGIMTAETGTYRWMAPEVLG-HSHYDQKADVFSFGVLLWELLTKKVPYELM------TPF
..||||||| . .|.|.||..    |..|||.|.      .. ||  .||...|||||.  ...|..|.|..|.|..|.|.|... |.         .. 
MGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDNHDQM

QVAVGVLQEELRPTIPQD-------------------AHPKFSQLLEWCWRTNPADRPDFSEI
|. . ... .|.  .|..                   ... . ....||.. .|..|| . .|
QMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQI
Kinase MLKz_a-2.AA S_TKc 302-555 26 2e-62 214.63 SMART 1-231 (231) Show / Hide 
Range on Protein: 302-555
Range on HMM: 1-231/231
Sequence Identity: 26% (70 aa)

LKRIKKILPSSNGDIYRGTFCG--QDVAIKVIKPETWTEHLQEFVHEIAIMRKVRHKNIVQFIGACTTPPDLCIVTEYMSG--GTVHDYLQKQKGN----
 . ..||   . |  |...  .  . ||||.||        . .  ||.|..| .|.|||...... .  .|..|.||..|  |...||..|....    
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK--------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRF

-LHLYVLLRIALDIAKGMDYLHQNNIIHRDLKASSLLMDENGVVKVADFGVARIQDQDGIMTAETGTYRWMAPEVLGHSHYDQ-KADVFSFGVLLWELLT
 ..  .  ...  |.....|.|...||||||| . .|.||  ..|..|||.||.       |   ||  .||||||   .|.  |.|. |.|..|.|.|.
PFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLC

KKVPYELMTPFQVAVGVLQEELRPTIPQDAHPKFSQLLEWCWRTNPADRPDFSEITL----VLKDIMS
 . |..  .....   ..             | . .... |.. .|..||   |.      . ..   
GYPPFP--QMQMMFKKIG------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF