Gene MLK-p1_f-2 (S.moellendorffii)

MLK-p1_f-2

Species: S.moellendorffii
Alias: MLK-p1_f-2
External Links:
Annotation:

Classification

Group: TKL
Family: MLK
Subfamily: MLK-plant1

Sequence

Name Sequence Type Origin Length Description Download
MLK-p1_f-2.AA Protein None 465 None Fasta, JSON
MLK-p1_f-2.NA RNA None 1398 None Fasta, JSON
MLK-p1_f-2.kin_dom Protein Kinase Domain None 253 None Fasta, JSON

Protein domain

Protein domains of MLK-p1_f-2.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase MLK-p1_f-2.AA Dicty4 189-441 47 3.8e-123 412.45 In-house 1-277 (277) Show / Hide 
Range on Protein: 189-441
Range on HMM: 1-277/277
Sequence Identity: 47% (131 aa)

LTIRELIGQGSCGSVYRGMWCGSDVAVKVF--SERGFSPALLDDFRKEVAIMRKVRHPNVLLFMGAVA----TPDNLCIVTEFLPRGSLFRLLHR-----
..| ..||.||.|.||.| | |..||||..     .|. ..| .|||||.|| | ||||..|||||      .|  .|||||..|.|.|..|||      
INIEQRIGKGSFGEVYKGTWRGKEVAVKKLNNHNQNFDENMLNEFRKEVHIMCKIRHPNICLFMGACTAPRSHPGKMCIVTEYMPKGNLYSLLHDKPSEQ

-KTPGLD--LRRR-LRMALDIARGMNYLHHCKPPIVHRDLKSSNLLVDKDWTV--GDFGLSR-LKHATLLTT--KSGRGTPQWMAPEVLRNEPSDERADV
 .   ||  |..| .|||.|.|||||.|| | | |.||||||.||||||.|.|  .|||||.  |  . ...  ..  ||| ||||||....| .| |||
QQSIKLDWPLIKRAMRMAFDAARGMNWLHCCNPVIIHRDLKSHNLLVDKNWRVKVCDFGLSQYMKKHEDHKDNQMTACGTPCWMAPEVMMHQPYNEKADV

YSFGVIVWELATEQVPWD--GMNPMQVVGAVGFMNQRLTIPPNTDPGFTALMEQCWQSDPKARPSFEEIIAR--IRE
|||| . ||..| | |    .|..||.| ||.    |. ||....| ...|.. ||  ||. |||||||| |    .
YSFGIVLWEILTRQEPYQKHHMPYMQFVRAVCNKKLRPPIPDWCPPSWKHLIQWCWDHDPQHRPSFEEIIQRRILEH
Kinase MLK-p1_f-2.AA DRK 189-441 43 9.3e-110 370.94 In-house 1-258 (258) Show / Hide 
Range on Protein: 189-441
Range on HMM: 1-258/258
Sequence Identity: 43% (112 aa)

LTIRELIGQGSCGSVYRGMWCGSDVAVKVFSERGFS-PALLDDFRKEVAIMRKVRHPNVLLFMGAVATPDNLCIVTEFLPRGSLFRLLHRKTPGLDLRRR
  |   || |..| |.|| | |. ||||           .| .|..|. .| . ||||. .|||.   |   ||..|..||||| . ||     .|  ..
IKIGNRIGRGNYGEVFRGTWRGTQVAVKMLFNHNINDENFLNEFHREINLMCQLRHPNICQFMGTCNNPPDICICMEYMPRGSLYNILHDESIEMDWPLM

LRMALDIARGMNYLHHCKPPIVHRDLKSSNLLVDKDWTV--GDFGLSR--LKHATLLTTKSGRGTPQWMAPEVLRNEPSDERADVYSFGVIVWELATEQV
..|..|.|.||.||| | | |.|||||| |||||  | |   |||||    ||    ...   ||| | |||||||..  | ||||||... ||..| | 
KQMMFDCAKGMIYLHCCNPIIIHRDLKSHNLLVDEHWQVKVADFGLSTRFKKHKQHKFAMTMCGTPCWTAPEVLRNQRYTEKADVYSFAIVLWECVTRQD

PWDGMNPMQVVGAVGFMNQRLTIPPNTDPGFTALMEQCWQSDPKARPSFEEIIARIRE
|  ||...||| .||    |. .|..  | ...||  ||  ||  |||..|.. |.  
PYFGMPTFQVVFSVGRHGMRPPMPQWCPPKYIQLMNDCWNEDPQHRPSMQECLERLEA
Kinase MLK-p1_f-2.AA TKL 195-439 30 2.5e-106 359.55 In-house 1-364 (364) Show / Hide 
Range on Protein: 195-439
Range on HMM: 1-364/364
Sequence Identity: 30% (115 aa)

IGQGSCGSVYRGMWCG----------SDVAVKVFSERGFSPALL-------------------------DDFRKEVAIMRKVRHPNVLLFMGAVATPDN-
||.|. | ||.| | |           |||||.|...  .   .                         . ...|. .|.. ||||...|||..  |.. 
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

------------LCIVTEFLPRGSLFRLLHRKTPGLDLRRRLRMALDIARGMNYLHHCK------PPIVHRDLKSSNLLVDKDWT---------------
            ||||.|. |.|||. .||       . .|.|.|||||||||||| ..      |||.||||||.|.|||..||               
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH-------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWCC

-VGDFGLSRLKHATLL-------------------TTKSGRGTPQWMAPEVLRNE----------------PSDERADVYSFGVIVWELATEQVPWDGMN
 ..|||||| .. .                     || . .|||.||||||||..                . .|..||||||.. ||..| ..|.....
KICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPYYDYP

PMQVV---------GAVGFMNQRLTIP------------PNTDPGFTALMEQCWQSDPKARPSFEEIIARI
.|...           |.  ..|..||            |...|..  ||..||..||..||||.||. |.
YMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
Kinase MLK-p1_f-2.AA TKL-Unique 191-439 39 6.7e-104 351.48 In-house 1-290 (290) Show / Hide 
Range on Protein: 191-439
Range on HMM: 1-290/290
Sequence Identity: 39% (114 aa)

IRELIGQGSCGSVYRGMWCGSDVAVKVFS-ERGFSPALLDDFRKEVAIMRKVR-HPNVLLFMGAVA----TPDNLCIVTEFLPRGSLFRLLH--------
. ..||.|..|.||.|.| |..||.|.|. . ..|. ....|..|| .| | . |||....||. .    .| |.|||.|..|.|||  .||        
FWNKIGEGGYGQVYKGKWRGYPVAIKQFHPNEDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNNNNNN

-RKTPGLDLRRRLRMALDIARGMNYLHHCKPPIVHRDLKSSNLLVDKD-----WTV--GDFGLSRLKHATLLTTKSGR---------GTPQWMAPEVLRN
 ..   |.. .|..||.|||.||.|||||.||| ||||||||.||| .     | .   |||||...   . .|...          |...||||||||.
NNNNCKLNMQQRVKMAIDIAQGMYYLHHCEPPIIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFRWMAPEVLRM

--EPSDERADVYSFGVIVWELATEQV------PWDGMNPMQVVGAVGF--MNQRLTIPPNTDPGFTALMEQCWQSDPKARPSFEEIIARI
  .  .| .||||||...||.|| ..      | .||.. |.  .| .   |.|..||..  . .. |..||| .||  ||||.||| |.
NFCQYSEKSDVYSFGIVLWEIATRKITKTYKKPYQGMDQEQWCEMVHYMEENYRPPIPNHCPKEYRDLIQQCWHHDPSQRPSFDEIIHRL
Kinase MLK-p1_f-2.AA MLK 189-439 35 3.3e-90 305.99 In-house 1-291 (291) Show / Hide 
Range on Protein: 189-439
Range on HMM: 1-291/291
Sequence Identity: 35% (103 aa)

LTIRELIGQGSCGSVYRGMWCGSD-----VAVKVFSERGFSPAL----LDDFRKEVAIMRKVRHPN----VLLFMGAVATPDN-LCIVTEFLPRGSLFRL
... | || || |.|..| | . |     |||| .  | |. .      .||..|. . |...|||    .  |.|. . | . .|||.|... |||...
IQFHEWIGSGSFGKVWKGRWRNKDIVAKIVAVKRVRARIFDKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQPPCHFCIVMEYCEGGSLYNV

LHRKTP-------------GLDLRRRLRMALDIARGMNYLHHCKP-PIVHRDLKSSNLLVD--------KDWTVGDFGLSRLKHATLLTTKSG-RGTPQW
|| ...               |.   .. ||..||||.|||  .| ||.||||||.|.|.|        ..  . |||.|| .| .  |.. . .||. |
LHGARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHSMAPKPIIHRDLKSHNILIDEICHDMHHGTLKICDFGTSRDWHQMC-TNMMSNAGTYAW

MAPEVL---RNEPSDERADVYSFGVIVWELATEQVPWD-GMNPMQVVGAVGFMNQRLTIPPNTDPGFTALMEQCWQSDPKARPSFEEIIARI
|||||.   |.|. .| .||.|.||. ||. | .|| . ...||..   |.  ..|..||.. ....  ||.|||..||. |||| .|.   
MAPEVIQQFRCEKYSEKCDVWSWGVVLWEMLTREVPYKQHYDPMAIAWWVAYNGLRPPIPSTCPEHWKKLMKQCWNQDPHKRPSFRQIVQHL
Kinase MLK-p1_f-2.AA Shk 189-444 42 5.6e-85 288.62 In-house 1-269 (269) Show / Hide 
Range on Protein: 189-444
Range on HMM: 1-269/269
Sequence Identity: 42% (115 aa)

LTIRELIGQGSCGSVYRGMWCGSDVAVKVFSERGFSPALLDDFRKEVAIMRKVRHPNVLLFMGAVA-TPDNLCIVTEFLPRGSLFRLLHRKTPGLD--LR
 .  ...|||| |.|| |   | .|||||     |. . . .|||||.|| |..|||..|||||   .|  . ||||  |.|.|  ||| .   ..  | 
INREDFLGQGSFGKVYKGRCRGKEVAVKVMHKQNFDENTMTSFRKEVHIMSKIFHPNICLFMGACTSQPGKCMIVTELMPKGNLEKLLHDQMVKKPFILY

RR-LRMALDIARGMNYLHHCKPPIVHRDLKSSNLLVDKDWTV--GDFGLSR-LKHATLLTT--KSGRGTPQWMAPEVLRNEPSDERADVYSFGVIVWELA
.| .||..| | ||| ||   . |.|||||..|||||..|.|  .|||.|   |  . |    |.  ||| ||||||. | | .| ||||||| | ||..
KRAMRMCRDAALGMNWLHGSNCNIIHRDLKTANLLVDQNWRVKVCDFGFSQYMKKHEMLKDKQKGAKGTPLWMAPEVMMNHPYNEKADVYSFGIILWEIL

TEQVPWD--GMNPMQVVGAVGFMNQRLTIPPNTDPGFTALMEQCWQSDPKARPSFEEIIAR--IRELLA
| | |      .  . . |.     |  ||  . .    | . ||  .|. ||||.||| |    . | 
TCQEPYPKHHSEYDKFYEAICNKKERPPIPDDCPKSLKHLIQKCWDHNPQRRPSFNEIIQRRILNHILI
Kinase MLK-p1_f-2.AA LRRK 189-441 29 4.5e-74 252.41 In-house 1-351 (351) Show / Hide 
Range on Protein: 189-441
Range on HMM: 1-351/351
Sequence Identity: 29% (103 aa)

LTIRELIGQGSCG-SVYRGMWCG----------------------------SDVAVKVFSERG--------------------------------FSPAL
| | |.||.|. | .|||. | |                            ..||.|..   .                                ...  
LKIEEQIGRGGFGTFVYRAKWRGQPVHVCRMHQKMLQPYMYQGARNSYDMCQWVAIKKWNRDPMTIDNDCNNSNNNNNLNNNNSEQVEDMDQNHEDCCRA

LDDFRKEVAIMRKVRHPNVLLFMGAVATPDNLCIVTEFLPRGSLFRLLH--RKTP------GLDLRRRLRMALDIARGMNYLHHCKPPIVHRDLKSSNLL
.  ||.||.||.. .|||..  .|    |  ||.|.|..| |.| ..||  ....       ..   .|. ||.||.||.||| ..|||.|||||| | |
FREFRHEVWIMSHLNHPNIVSLKGFCIHP--LCMVMEYAPHGDLYHFLHNKKQDGFHFMKAHISWMLKLKIALQIAKGMEYLHSHNPPIIHRDLKSPNIL

VDKDW--------------TVGDFGLSRLKHATLLT--TKSGRGTPQWMAPEVLR---NEPSDERADVYSFGVIVWELATEQ-VPWDGMN-P-----MQV
. .                ...|||.||.  .....  .|   |.|.|||||..|   .|  .| .|.||||.| ||| | |  | |... .     |  
LWSSPQNHSPNYPNAHVCAKIADFGISRMF-QCFHMGVAKGCVGNPGWMAPEIMRYNGEEEYTEKVDCYSFGMILWELLTRQHHPFDEHDFFDHMQWMEQ

VGAVGFMNQRLTIPPN-TDP-----GFTALMEQCWQSDPKARPSFEEIIARIRE
.       .| |||..   |      . .|...||| ||| ||.|..|. |. .
IEDKIIEGLRPTIPQHYCPPCQPWHMYQDLIQHCWQHDPKKRPHFSQIVKRLSQ
Kinase MLK-p1_f-2.AA Dicty4-Unclassified 189-439 35 4.9e-72 245.64 In-house 1-263 (263) Show / Hide 
Range on Protein: 189-439
Range on HMM: 1-263/263
Sequence Identity: 35% (94 aa)

LTIRELIGQGSCGSVYRGMWCGSDVAVKVFSERGFSPA--LLDDFRKEVAIMRKVRHPNVLLFMGAVATP----DNLCIVTEFLPRGSLFRLLH----RK
. |   ||.|    |..| | | ||||| | |  |.    ...||.|||.|.  . ||| .   |.   |      .|||.||...| || . |     .
IQIDQFIGKGHFSKVHKGNWKGKDVAVKKFNENKFKFREEMIQDFKKEVEILGSIQHPNLVKCYGYCINPRSHKSTMCIVMEFMHKGNLFEVIHSKPSEQ

TPGLDLRR--RLRMALDIARGMNYLHHCKPPIVHRDLKSSNLLVDKDWT--VGDFGLSRLKHATLLTTKSGRGTPQWMAPEVLRNEPSDERADVYSFGVI
   . |     ...|.|||.|| .||     ..|||.||||.|.||.    ..|||.||    .   |  . ||| | .||.|. |    ..||||....
QQPIKLDDTLIIKYAFDIAQGMQHLHTRN--FIHRDIKSSNILMDKHFNIKIADFGISRVIDFNFNMTTIA-GTPKWESPECLMHESYNQKSDVYSYAMM

VWELATEQVPWDGMN-PMQVVGAVGFMNQRLTIPPNTDPGFTALMEQCWQSDPKARPSFEEIIARI
 .||||   |. .   .| .   |     |  || | |. .  |   ||  ||. ||....|| . 
LYELATGDEPYQEIQSIMNAARSVCDKKLRPKIPDNCDNFWKKLIKWCWHNDPNKRPTMNQIIQYL
Kinase MLK-p1_f-2.AA CZAK 189-439 37 1.5e-68 234.09 In-house 1-279 (279) Show / Hide 
Range on Protein: 189-439
Range on HMM: 1-279/279
Sequence Identity: 37% (106 aa)

LTIRELIGQGSCGSVYRGMWCGSDVAVKVFSERGFSPALL----DDFRKEVAIMRKVRHPNVLLFMGA--VATPDNLCIVTEFLPRGSLFRLLHRKTPGL
|..   ||||  | ||.. | | |||.|      |           | |||.|| | .|||.. |.||     |.  |||.|.   ||| |||  .   .
LKFGQTIGQGFFGEVYKAYWRGKDVAIKIIHRNQFRNKDENKEENMFQKEVSIMSKLCHPNCVQFLGACSEDGPNHHCIVMEWMGGGSLRRLLTDHYFYH

DL--RRRLRMALDIARGMNYLHH-CKP-PIVHRDLKSSNLLVDKDWT---------------VGDFGLSRLKHATLLTTKSGRGTPQWMAPEVLRNEPSD
      .. ||.||||||||||   || ||.|||| |.| | |   |               . ||||||..        .  |   |||||.   |   
KQNPHLQWNMAIDIARGMNYLHDNWKPNPILHRDLSSRNILLDHSYTPKNPVVSSRQDIICKINDFGLSREMMEQPFEMTQTMGCLCWMAPECFKGENYT

ERADVYSFGVIVWELATEQVPWDGMNPMQVVGAVGFMNQRLTIPPNTDPGFT---ALMEQCWQSDPKARPSFEEIIARI
| .|||||| |.|.. |   |  .| ||       . | |. .|  .||       |.|.|| . |  |||| .|.   
EKVDVYSFGMILWCIITCDQPYQNMQPMKMAHLAAYENYRPPMPQPMDPMWKNLGELIEMCWNKNPDERPSFKQILQHL
Kinase MLK-p1_f-2.AA Pkinase_Tyr 189-439 31 3.8e-68 231.41 Pfam 1-270 (270) Show / Hide 
Range on Protein: 189-439
Range on HMM: 1-270/270
Sequence Identity: 31% (85 aa)

LTIRELIGQGSCGSVYRGMWC------GSDVAVKVFSERGFSPAL--LDDFRKEVAIMRKV-RHPNVLLFMGAVA-TPDN--LCIVTEFLPRGSLFRLLH
.|. . .|.|. |.||.| |       . .||||.    | ..    ..|| .|..||..  .|||.. ..|..    .   ..||.|. | |.|   |.
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR

RK---TPGLDLRRRLRMALDIARGMNYLHHCKPPIVHRDLKSSNLLVDKDWTV--GDFGLSRLK--HATL-LTTKSGRGTPQWMAPEVLRNEPSDERADV
..    . |.. . | |...||.||.||.  .  ..||||   | ||... .|  .||||.|.     .   ....|.    |||||....    .  ||
KHREDKQPLTMKDLLQMCWQIAKGMEYLESKN--CIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECINYGKFTTKSDV

YSFGVIVWELAT-EQVP-WDGMNPMQVVGAVGFMNQRLTIPPNTDPGFTALMEQCWQSDPKARPSFEEIIARI
.||||  ||. |  . | . || . .|. ...  ..|. .|.|. .    || |||. ||. ||.|.||. ..
WSFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYRMPCPENCPDEIYDLMKQCWHYDPEDRPTFSEIHEQL
Kinase MLK-p1_f-2.AA Pkinase 189-439 24 7.5e-67 233.21 Pfam 1-293 (293) Show / Hide 
Range on Protein: 189-439
Range on HMM: 1-293/293
Sequence Identity: 24% (73 aa)

LTIRELIGQGSCGSVYRGMWCGSD--VAVKVFSERGFSPALLDDFRK--EVAIMRKVRHPNVLLFMGAVATPDNLCIVTEFLPRG----SLFRLLH-RKT
..| . ||.|| |.||.... |.   ||||... |. ..  .   |.  |..||....|||.. . ... ..|....|.|... |    .||.... .. 
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

PGL--DLRRRLRMALDIARGMNYLHHCKPPIVHRDLKSSNLLVDKDWTV------GDFGLSRLK-HATLLTTKSGRGTPQWMAPEVLR-NEPSDERADVY
 ..  . .   .... |.||..|.| .   |.|||||..|.|.|.. ..      .||||.... .     ...  ||| .|||||.| ... . ..|..
GCFYFSEWECKFYMYQILRGLEYCHSM--GIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMW

SFGVIVWELATEQVPWDGM------NPMQVVGAVGFMNQRLTIP-------------------PNTDPGFTALMEQCWQSDPKARPSFEEIIAR--I
|.|.|..|... . |..|       ..||..  ..    .  .|                   .|... .  ... |.. ||| ||..|.|     .
SCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase MLK-p1_f-2.AA Dicty5 189-443 34 4.4e-62 212.48 In-house 1-260 (260) Show / Hide 
Range on Protein: 189-443
Range on HMM: 1-260/260
Sequence Identity: 34% (93 aa)

LTIRELIGQGSCGSVYRGMWCGSDVAVKVFSERG---FSPALLDDFRKEVAIMRKVR--HPNVLLFMGAVATPDNL-CIVTEFLPRGSLFRLLHRKTP--
  . . |  |. | || |   | |||.||.|  .   |    ...| .||.||  .   |||.  . ||    |.   .|||.  .|||| .|  .    
VSFHDWIASGASGRVYNGIYKGMDVAIKVYSQENCMCFD---WNEFYREVTIMSIFQSDHPNFIRCYGAHQYNDKYPFHVTEYCHNGSLFNYLNDQRKTT

--GLDLRRRLRMALDIARGMNYLHHCKPPIVHRDLKSSNLLVDKDWTVG--DFGLSR-LKHATLLTTKSGRGTPQWMAPEVLRNEPSDERADVYSFGVIV
   .    .| ||.|||..| .||     |.|||||| | |. ..|..   ||| ||    .   |.    ||. |||.|.    | .. .||||||.. 
GQPIAYFQQLHMAIDIAQSMRHLHSMN--IIHRDLKSMNFLITENWKIKIIDFGTSRFVDNRYHMTMH--VGTQCWMACELFNGQPYHQKCDVYSFGIVL

WELATEQVPWDGMNPMQVVGAVGFMNQRLTIPPNTDPGFTALMEQCWQSDPKARPSFEEIIARIRELL
||. |   | | .|       |     | |||.     .  | . |||  |. |||| ||.. .. . 
WEMFTRKEPYDNINNWNIPVMV-MKGERPTIPKDCPTEISNLIKKCWQQKPHNRPSFKEICKYFESII
Kinase MLK-p1_f-2.AA TyrKc 189-439 31 1.6e-60 208.29 SMART 1-280 (280) Show / Hide 
Range on Protein: 189-439
Range on HMM: 1-280/280
Sequence Identity: 31% (91 aa)

LTIRELIGQGSCGSVYRGMWCGSDVAVKVFSERGFSPALLDDFRKEVAIMRKV--RHPNVLLFMGAVATP-------DNLCIVTEFLPRGSLFRLLHRKT
.|  . .| |  | ||.|.|   .||||.  |       . ||..|  ||.|.  .|||.. . |.. ..       . |.||.|. | |.|   |... 
ITLGKKLGEGAFGEVYKGTWK-IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHR

PGLDLRRRLRMALDIARGMNYLHHCKPPIVHRDLKSSNLLVDKD--WTVGDFGLSRLKHAT-------LLTTK----SGR--GTPQWMAPEVLRNEPSDE
| | ..  | ....||.||.|||.   ...||||   | ||...    ..||||||  .            .|    .|.      |||||...     .
PKLCMKDLLSFCWQIACGMEYLHSK--NCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTT

RADVYSFGVIVWELATE-QVPWDG-----MNPMQVVGAVGFMNQRLTIPPN--------TDPGFTALMEQCWQSDPKARPSFEEIIARI
  ||.||||  ||. |  | |. |     |.. .|.  |     |. .|||          .    .|.|||. ||. ||.|.||. ..
KSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVK-QGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase MLK-p1_f-2.AA S_TKc 189-443 23 2.6e-59 204.25 SMART 1-231 (231) Show / Hide 
Range on Protein: 189-443
Range on HMM: 1-231/231
Sequence Identity: 23% (65 aa)

LTIRELIGQGSCGSVYRGMWCG--SDVAVKVFSERGFSPALLDDFRKEVAIMRKVRHPNVLLFMGAVATPDNLCIVTEFLPR--GSLFRLLHRKTPG---
 .| ..||.|. |.||.. . .    ||.|. .         ...|.|..|..| .|||.  . ..  . |.|..|.|...   |.||...... ..   
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLR

--LDLRRRLRMALDIARGMNYLHHCKPPIVHRDLKSSNLLVDKDWTV--GDFGLSRLKHATLLTTKSGRGTPQWMAPEVLRNEPSDE-RADVYSFGVIVW
  ..  .  ...  |.....|.|     |.||||| .|.|.|.  ..  .||||.|.        ..  ||| .||||||   . .  ..|..|.|.|..
FPFPE-HARFYMYQICCALEYCHSH--GIIHRDLKPENILLDE--HIKICDFGLARQL-------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILY

ELATEQVPWDGMNPMQVVGAVGFMNQRLTIPPNTDPGFTALMEQCWQSDPKARPSFEEIIA-----RIRELL
|... . |..  .....   .|            .| .  ....|.| ||. ||.  |. .     .. . .
EMLCGYPPFP--QMQMMFKKIG------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF