Gene RLCK17_a-2 (S.moellendorffii)
RLCK17_a-2
Species: S.moellendorffii
Alias: RLCK17_a-2
External Links:
Annotation:
Sequence
Name | Sequence Type | Origin | Length | Description | Download |
---|---|---|---|---|---|
RLCK17_a-2.AA | Protein | None | 523 | None | Fasta, JSON |
RLCK17_a-2.NA | RNA | None | 1572 | None | Fasta, JSON |
RLCK17_a-2.kin_dom | Protein Kinase Domain | None | 202 | None | Fasta, JSON |
Protein domains of RLCK17_a-2.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.
Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
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Kinase | RLCK17_a-2.AA | IRAK | 68-277 | 39 | 1.4e-72 | 247.43 | In-house | 1-229 (317) | Show / Hide |
Range on Protein: 68-277 Range on HMM: 1-229/317 Sequence Identity: 39% (91 aa) FKAECLLGEGGFGRVYKGRLENSGQVVAVK----QLDRNGLQGNREFLV---EVLMLSLLHHPNLVNLIGYCADGDQRLLVYEFMPLGCLEDHLHDIPPE | .. ..|||||| ||.|.. | . ..||| | . . ..|. |. .....|||.| | |||..... |||..|| | ||| |. . FHKDNRIGEGGFGCVYRGQWKNTTGIYAVKKLKEMADMSWNEHWQRFQQSYNELKVCCRCRHPNIVPLYGYCTERQCHCLVYPYMPNGSLEDRLWCQDGQ KAP--LDWNTRMKIAAGAAMGLEYLHDKA-NPPVIYRDFKSSNILLDNNFHPKLSDFGLAKLG-PVGDKTHVST------RVMGTYGYCAPEYAM--TGQ .| | | .| .|. |.| |...||.. |.| .| ||.||||| .| ||..||||. | | ..| . . .| || | .||. .|| CPPKPLSWHQRCSICWGTACGIQFLHQNHPCTPIIHGDIKSANILLDQHFTPKICDFGLHRFGHPASHKEKQTYTCMMTSHVRGTTWYMPPEFIRDPQGQ LTLKSDVYSFGVVLLELITGRKAIDNSRP || |.||||||.||||..||..| .. || LTKKTDVYSFGIVLLEVLTGCRAVYDDRP |
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Kinase | RLCK17_a-2.AA | TKL | 74-270 | 25 | 8.4e-69 | 234.89 | In-house | 1-287 (364) | Show / Hide |
Range on Protein: 74-270 Range on HMM: 1-287/364 Sequence Identity: 25% (77 aa) LGEGGFGRVYKGRLEN--------SGQVVAVKQLDRNGLQG--------------------------NREFLVEVL-MLSLLHHPNLVNLIGYCADGDQ- .|.|||| ||||.. . .|..||||.. .. . .|.|..|.. |.| |.|||.| ..||| .... IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG ------------RLLVYEFMPLGCLEDHLHDIPPEKAPLDWNTRMKIAAGAAMGLEYLHDKAN-----PPVIYRDFKSSNILLDNNFH------------ .|.|..| |.|...|| |. |...| ..| |..||| . ||.|.|| ||.|||.|.|.. CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH----------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNAD --PKLSDFGLAK-LGPVGDKTHVSTR----------------VMGTYGYCAPEYAM----------------TGQLTLKSDVYSFGVVLLELITGRK .|..||||.. . . |.... .| . ||....||| . .. . |.||||||.|| |..|... WCCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCR |
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Kinase | RLCK17_a-2.AA | LRRK | 68-269 | 27 | 1.5e-48 | 167.59 | In-house | 1-279 (351) | Show / Hide |
Range on Protein: 68-269 Range on HMM: 1-279/351 Sequence Identity: 27% (79 aa) FKAECLLGEGGFG-RVYKGRLEN--------------------------SGQVVAVKQLDRNG----------------------------------LQG .| | ..|.|||| .||...... ..| ||.|...| . . LKIEEQIGRGGFGTFVYRAKWRGQPVHVCRMHQKMLQPYMYQGARNSYDMCQWVAIKKWNRDPMTIDNDCNNSNNNNNLNNNNSEQVEDMDQNHEDCCRA NREFLVEVLMLSLLHHPNLVNLIGYCADGDQRLLVYEFMPLGCLEDHLHDIPPEK-----APLDWNTRMKIAAGAAMGLEYLHDKANPPVIYRDFKSSNI ||| || ..| |.|||.|.|.|.| . . .| |..|.| | ..||. . | ..|... ||| | |.|||| ..|||.|.|| || || FREFRHEVWIMSHLNHPNIVSLKGFCIHP--LCMVMEYAPHGDLYHFLHNKKQDGFHFMKAHISWMLKLKIALQIAKGMEYLH-SHNPPIIHRDLKSPNI LL---D---------NNFHPKLSDFGLAKLGPVGDKTHVSTRVMGTYGYCAPEYAMTG---QLTLKSDVYSFGVVLLELITGR || . .. . |..|||. . ... | .. |. |..||| . . | |.|.||||..| ||.|.. LLWSSPQNHSPNYPNAHVCAKIADFGISRMF-QCFHMGVAKGCVGNPGWMAPEIMRYNGEEEYTEKVDCYSFGMILWELLTRQ |
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Kinase | RLCK17_a-2.AA | TK | 68-267 | 18 | 1.3e-47 | 157.19 | In-house | 1-389 (486) | Show / Hide |
Range on Protein: 68-267 Range on HMM: 1-389/486 Sequence Identity: 18% (72 aa) FKAECLLGEGGFG---RVYKGRLENSG-------------------------QVVAVKQLDRNGLQGNRE-----------------FLVEVLMLS--LL . . |||| || .||||.... . . ||||.| . .| .. | |.. |. ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG HHPNLVNLIGYCADG------------DQRLLVYEFMPLGC----LEDHLHDIPPEKAP----------------------------------------- ||||.|.|.|.| .| ..| |.||.|. | |.|.. .|.. . HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY -------------------------------LDWNTRMKIAAGAAMGLEYLHDK----ANPPVIYRDFKSSNILLDNNFH-----------PKLSDFGLA |. ... ... .| |.||||.| . .. || |.|...| . |..||||. DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFI-QNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLS K-----LGPVGDKTHVSTRVMGTYG---------------------------YCAPEYAM---------TGQLTLKSDVYSFGVVLLELIT . | .. . .|. . .. ..||| . .| | ||||.||||.. |. | RQGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFT |
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Kinase | RLCK17_a-2.AA | TKL-Unique | 73-268 | 35 | 2.7e-46 | 160.13 | In-house | 4-224 (290) | Show / Hide |
Range on Protein: 73-268 Range on HMM: 4-224/290 Sequence Identity: 35% (80 aa) LLGEGGFGRVYKGRLENSGQVVAVKQLD-RNGLQGN--REFLVEVLMLSLLH-HPNLVNLIGYCA----DGDQRLLVYEFMPLGCLEDHLHD------IP ..||||.|.|||| . | ||.||. ... .|| || .. || |||.| ..|||. . .. .| |..|.| | |.||. KIGEGGYGQVYKG--KWRGYPVAIKQFHPNEDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNNNNNNN PEKAPLDWNTRMKIAAGAAMGLEYLHDKANPPVIYRDFKSSNILLDNN-----FHPKLSDFGLAKLGPVGDKTHVS-------TRVMGTYGYCAPEYAMT ... .|... |.|.| .| |..||| . | .| || ||||.|.||| . |..||||.|. .|. .. . ..|.. . ||| . NNNCKLNMQQRVKMAIDIAQGMYYLHHCEPP-IIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFRWMAPEVLRM --GQLTLKSDVYSFGVVLLELITG | . ||||||||.|| |..|. NFCQYSEKSDVYSFGIVLWEIATR |
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Kinase | RLCK17_a-2.AA | S_TKc | 68-345 | 23 | 4.5e-46 | 160.31 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 68-345 Range on HMM: 1-231/231 Sequence Identity: 23% (67 aa) FKAECLLGEGGFGRVYKGRLENSGQVVAVKQLDRNGLQGNREFLVEVLMLSLLHHPNLVNLIGYCADGDQRLLVYEFMPL--GCLEDHLHDIPPEKAP-- .. ..|.|.||.|||.| ..|..||.|... . .. |. .|. ||||.|.|.... | | .| |... | | |.... .... . YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFP LDWNTRMKIAAGAAMGLEYLHDKANPPVIYRDFKSSNILLDNNFHPKLSDFGLAKLGPVGDKTHVSTRVMGTYGYCAPEYAMTGQLTL-KSDVYSFGVVL .. . .... . .|||.|.. . .|.|| | .|||||. | |..|||||.. | . || |.||| . . |.|..|.|..| FPE-HARFYMYQICCALEYCHSH-G--IIHRDLKPENILLDE--HIKICDFGLARQL---------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCIL LELITGRKAIDNSRPAGEHNLVAWARPLFKDRRKFPSMSDPLLQGRYPMRGLYQALAVAAMCLQEQAATRPLIADVVT------ALNYL |...|. . .. . . . .|. ||| . || . .. . . .. YEMLCGYPPFP--------QMQMMFKKIG----------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF |
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Kinase | RLCK17_a-2.AA | Pkinase | 68-269 | 29 | 1.7e-43 | 154.86 | Pfam | 1-209 (293) | Show / Hide |
Range on Protein: 68-269 Range on HMM: 1-209/293 Sequence Identity: 29% (64 aa) FKAECLLGEGGFGRVYKGRLENSGQVVAVKQLDRNGLQG--NREFLV--EVLMLSLLHHPNLVNLIGYCADGDQRLLVYEFMPLG----CLEDHLHDIPP .. . .|.|.||.|||.. ..|..||||.... . ... . |. .. |.||| | |.... |.| .| |... | | |... YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYIST--W EKAPL--DWNTRMKIAAGAAMGLEYLHDKANPPVIYRDFKSSNILLDNNFHP----KLSDFGLAKLGPVGDKTHVSTRVMGTYGYCAPEYAM-TGQLTLK .. .. .... ... . ||||.|.. .|.|| |..|||.||| |. |..||||||. . . | . ||..|.||| . . | RHGCFYFSEWECKFYMYQILRGLEYCHSM---GIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD-Y-NNS-MTTFCGTPWYMAPEVIRGGQYYGPK SDVYSFGVVLLELITGR .|..|.|..| |...|| VDMWSCGCILYEMLCGR |
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Kinase | RLCK17_a-2.AA | Dicty4 | 68-268 | 36 | 3e-40 | 132.05 | In-house | 1-213 (277) | Show / Hide |
Range on Protein: 68-268 Range on HMM: 1-213/277 Sequence Identity: 36% (79 aa) FKAECLLGEGGFGRVYKGRLENSGQVVAVKQL--DRNGLQGNR--EFLVEVLMLSLLHHPNLVNLIGYCA----DGDQRLLVYEFMPLGCLEDHLHDIPP . | ..|.|.|| ||||. |. |||| | . .. |. ||. || .. . |||.. . |.| . | |.|| | |. ||| | INIEQRIGKGSFGEVYKGTWR--GKEVAVKKLNNHNQNFDENMLNEFRKEVHIMCKIRHPNICLFMGACTAPRSHPGKMCIVTEYMPKGNLYSLLHDKPS ---EKAPLDWNTRMK---IAAGAAMGLEYLHDKANPPVIYRDFKSSNILLDNNFHPKLSDFGLAK-LGPVGDKTH-VSTRVMGTYGYCAPEYAMTGQLTL .. .||| .. . .| || |. .|| || .| || ||.|.| | |. | .||||.. .. |.. .| . || .. ||| | . EQQQSIKLDWPLIKRAMRMAFDAARGMNWLHC-CNPVIIHRDLKSHNLLVDKNWRVKVCDFGLSQYMKKHEDHKDNQMT-ACGTPCWMAPEVMMHQPYNE KSDVYSFGVVLLELITG |.|||||| || |. |. KADVYSFGIVLWEILTR |
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Kinase | RLCK17_a-2.AA | MLK | 68-269 | 28 | 1.7e-39 | 134.69 | In-house | 1-233 (291) | Show / Hide |
Range on Protein: 68-269 Range on HMM: 1-233/291 Sequence Identity: 28% (68 aa) FKAECLLGEGGFGRVYKGRLENSG---QVVAVKQLDRNG----LQG--NREFLVEVLMLSLLHHPN----LVNLIGYCADGDQ-RLLVYEFMPLGCLEDH .. . .|.|.|| |.||| | .||||. . . . ..| |. |. | ||| . . | |.. . ..| |... |.| . IQFHEWIGSGSFGKVWKGRWRNKDIVAKIVAVKRVRARIFDKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQPPCHFCIVMEYCEGGSLYNV LHDIPPEKA----------PLDWNTRMKIAAGAAMGLEYLHDKANPPVIYRDFKSSNILLDN------NFHPKLSDFGLAKLGPVGDKTHV---STRVMG ||..... . | |..| | |..||| .| .|.| || ||.|||.|. . . | .|||... |... . .| LHGARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHSMAPKPIIHRDLKSHNILIDEICHDMHHGTLKICDFGTSR-----DWHQMCTNMMSNAG TYGYCAPEY---AMTGQLTLKSDVYSFGVVLLELITGR || . ||| . .. . |.||.|.|||| |..|.. TYAWMAPEVIQQFRCEKYSEKCDVWSWGVVLWEMLTRE |
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Kinase | RLCK17_a-2.AA | Dicty4-Unclassified | 68-268 | 34 | 1.8e-37 | 125.85 | In-house | 1-204 (263) | Show / Hide |
Range on Protein: 68-268 Range on HMM: 1-204/263 Sequence Identity: 34% (74 aa) FKAECLLGEGGFGRVYKGRLENSGQVVAVKQLDRNGLQGN----REFLVEVLMLSLLHHPNLVNLIGYCADG----DQRLLVYEFMPLGCLEDHLHDIPP . .|.| | .|.|| | |||| . | . .|. || .| .. ||||| . ||| | |||. | | | | IQIDQFIGKGHFSKVHKGNWK--GKDVAVKKFNENKFKFREEMIQDFKKEVEILGSIQHPNLVKCYGYCINPRSHKSTMCIVMEFMHKGNLFEVIHSKPS EKA-PLDWNT--RMKIAAGAAMGLEYLHDKANPPVIYRDFKSSNILLDNNFHPKLSDFGLAKLGPVGDKTHVSTRVMGTYGYCAPEYAMTGQLTLKSDVY |. |. . .|.| | |. .|| . .| || ||||||.| .| | |||.. | | . | . || .|| | . ||||| EQQQPIKLDDTLIIKYAFDIAQGMQHLHTRN---FIHRDIKSSNILMDKHFNIKIADFGISR---VIDFNFNMTTIAGTPKWESPECLMHESYNQKSDVY SFGVVLLELITG |....| ||.|| SYAMMLYELATG |
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Kinase | RLCK17_a-2.AA | TyrKc | 68-342 | 26 | 1.6e-36 | 128.58 | SMART | 1-280 (280) | Show / Hide |
Range on Protein: 68-342 Range on HMM: 1-280/280 Sequence Identity: 26% (81 aa) FKAECLLGEGGFGRVYKGRLENSGQVVAVKQLDRNGLQGNREFLVEVLMLSLL--HHPNLVNLIGYCADG-------DQRLLVYEFMPLGCLEDHLHDIP . . |||| ||.||||.. . |||| | . ..|. | ... | ||||.|.|.|.| .. .. ..| |.||.|.| |.|.. ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA---REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHR PEKAPLDWNTRMKIAAGAAMGLEYLHDKANPPVIYRDFKSSNILLDNNFHPKLSDFGLAKLGPVG-------DKTHV----STRVMGTYGYCAPEYAMTG |. | . . ... .| | ||||.| ..| || |.|...|.. | |||||.. . . | .. ... | . .||| ..| PK---LCMKDLLSFCWQIACGMEYLHSK---NCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYG QLTLKSDVYSFGVVLLELITGRKAIDNSRPAGE------HNLVAWARPLFKDRRKFPSM----SDPLLQGRYPMRGLYQALAVAAMCLQEQAATRPLIAD | ||||.||||.. |. | . | . | . .. .|.. | | . . . .| .|... || .. KFTTKSDVWSFGVCMWEIFT-----YGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMS-------F-VCCPDEMYQIMKQCWHEDPEDRPTFSE VVTAL .. . IHECF |
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Kinase | RLCK17_a-2.AA | TK-Unique | 68-267 | 26 | 3.6e-36 | 122.26 | In-house | 1-234 (294) | Show / Hide |
Range on Protein: 68-267 Range on HMM: 1-234/294 Sequence Identity: 26% (63 aa) FKAECLLGEGGFGRVYKGRLENSG------QVVAVKQLD-RNGLQGNREFLVEVLMLSLLH-HPNLVNLIGYCADGD-QRLLVYEFMPLGCLEDHLHDIP .. . ..||| || |..| ... ..||||.| .. .. ..|| | |.. | |||.|...|.| . | . ....|..| |.|...|. LEVGDVIGEGAFGQVWRGEVWGIWKHWDKQKCVAVKMLKDNATDTDKQDFLKEIQMMKELGDHPNIVQCLGCCTKSDEPWMIIMEYCPCGNLQHYLRTCR PE----------------------KAPLDWNTRMKIAAGAAMGLEYLHD--KANPPVIYRDFKSSNILLDNNFHPKLSDFGLAKLGPVGDKTHVS-TRVM |. ..|.. . .| . |.|.|||. | ...|| ..|.|| ... |..|||.|. . . .. . .. . PAMRQHQTYGNLKFDFHHMPDKPRTEPISPKDLYHFAWQIACGMEYLASQRKK---IVHRDLCARNVLLTEDKVCKICDFGMARDVYTNGVYSMMCSQGR GTYGYCAPEYAM--TGQL-TLKSDVYSFGVVLLELIT . ..|||. .|. | ||||.||||.. |. | IPIRWMAPESLKCYHGMYHTTKSDVWSFGVLMWEIFT |
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Kinase | RLCK17_a-2.AA | LISK | 73-219 | 37 | 1.6e-33 | 106.11 | In-house | 1-154 (296) | Show / Hide |
Range on Protein: 73-219 Range on HMM: 1-154/296 Sequence Identity: 37% (59 aa) LLGEGGFGRVYKGRLENSGQVVAVKQLDR-----NGLQGNREFLVEVLMLSLLHHPNLVNLIGYCAD-GDQRLLVYEFMPLGCLEDHLHDIPPEKAPLDW .|.|.|| ||||.. .|||.|.|.. | | . .| || |. .| ||| |. .| | .| .| |.. |.|.. |.| . | || | EIGKGFFGKVYKGTHRQTGQVMAIKMIHRQPNDPNDPEYQKFMLREVQMMKNLRHPNIVQFMGVCYHNDGQLHIVTEYINGGDLHQYLKDMDKHKIPLPW NTRMKIAAGAAMGLEYLHDKANPPVIYRDFKSSNILLDNN----FHPKLSDFGLAKL |.||| . | |..|||.. .| || || |.|...| . |. |||.|.. PQRVKIALDIACGMSYLHSMN---IIHRDLKSKNCLVRENDNNQWRIKVCDFGFARM |
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Kinase | RLCK17_a-2.AA | Pkinase_Tyr | 68-186 | 35 | 8.4e-32 | 108.33 | Pfam | 1-130 (270) | Show / Hide |
Range on Protein: 68-186 Range on HMM: 1-130/270 Sequence Identity: 35% (46 aa) FKAECLLGEGGFGRVYKGRLE----NSGQVVAVKQLDRNGLQGN----REFLVEVLMLSLL-HHPNLVNLIGYCA-DGDQ--RLLVYEFMPLGCLEDHLH . |||| ||.||||.. | .. |||| | ..| ..|. |. ... | ||||.|.|.| | .|.. ..| |.||.|.| |.|. ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR DIPPEKAPLDWNTRMKIAAGAAMGLEYLHDK . ..| ||. . .... |.|.|||..| KHREDKQPLTMKDLLQMCWQIAKGMEYLESK |
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Kinase | RLCK17_a-2.AA | Pkinase_Tyr | 200-270 | 35 | 2.8e-09 | 32.05 | Pfam | 141-213 (270) | Show / Hide |
Range on Protein: 200-270 Range on HMM: 141-213/270 Sequence Identity: 35% (26 aa) NILLDNNFHPKLSDFGLAKLGPVGDKT-HVSTRVMGTYGYCAPEYAMTGQLTLKSDVYSFGVVLLELIT-GRK |.|...|.. | .|||||.. | .... . .||| ..| | ||||.||||.. |..| |.. NCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECINYGKFTTKSDVWSFGVLMWEIFTYGEQ |
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Kinase | RLCK17_a-2.AA | LISK | 252-271 | 60 | 2e-08 | 23.27 | In-house | 219-238 (296) | Show / Hide |
Range on Protein: 252-271 Range on HMM: 219-238/296 Sequence Identity: 60% (12 aa) KSDVYSFGVVLLELITGRKA ..||.|||.||.|.||..|| SCDVFSFGIVLCEIITRVKA |