Gene RLCK-OS3_b (S.moellendorffii)

RLCK-OS3_b

Species: S.moellendorffii
Alias: RLCK-OS3_b
External Links:
Annotation:

Classification

Group: TKL
Family: IRAK
Subfamily: RLCK-OS3

Sequence

Name Sequence Type Origin Length Description Download
RLCK-OS3_b.AA Protein None 576 None Fasta, JSON
RLCK-OS3_b.NA RNA None 1731 None Fasta, JSON
RLCK-OS3_b.kin_dom Protein Kinase Domain None 196 None Fasta, JSON

Protein domain

Protein domains of RLCK-OS3_b.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase RLCK-OS3_b.AA TKL 299-561 21 9.3e-60 204.85 In-house 1-364 (364) Show / Hide 
Range on Protein: 299-561
Range on HMM: 1-364/364
Sequence Identity: 21% (79 aa)

LGEGSAGKVYIGQLPS---------GKLVAVKRILKER-----------------------------KVETFYKEVELLARIRHPNLTALLGYCRSKHV-
.|.|. |.|| |..           || ||||.. ..                                ... .|. .. |.||||.  ..||| .    
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

------------CLLVYEYMSNGDLAQKLLRKDGPALTWDQRIQIAIDCARGLTYLHEC-P----EGPVVHRDIKPTNILLNGLLE--------------
            . .|.||...|.|   |.        |.||...|.|.|||. ||| . |      |..|||.|. |||..  ..              
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH--------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWC

AKLSDFGLSKIIELDASHVSTE------------------IKGTTGYLDPEYLILG----------------QLTEASDVYSFGIVLLQLMSGRKAIDND
.|..|||||. .. . .   |.                  . ||.... || |                   . .|..|||||||||  ......  ...
CKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPYYDY

TRVNRSIVEMVSTLFLHDNQ--GLSQLLDPRLDC----DVPLPAFQKLAEVAHLCVQPRSYDRPSISEVLHDL
    . .    . ...  .   ||  ...|.  .      . .. . ... .  | ..   .||| .|.|. |
PYMPMIFQDP-FEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
Kinase RLCK-OS3_b.AA IRAK 293-561 28 2.2e-55 190.31 In-house 1-317 (317) Show / Hide 
Range on Protein: 293-561
Range on HMM: 1-317/317
Sequence Identity: 28% (91 aa)

FSNASLLGEGSAGKVYIGQLPSGK-LVAVKRILKERKVET------FYK---EVELLARIRHPNLTALLGYCRSKHVCLLVYEYMSNGDLAQKLLRKDG-
|. . ..|||  | || ||.      .|||.. .......      |     |.....|.||||. .|.|||       |||.||.|| |   |   || 
FHKDNRIGEGGFGCVYRGQWKNTTGIYAVKKLKEMADMSWNEHWQRFQQSYNELKVCCRCRHPNIVPLYGYCTERQCHCLVYPYMPNGSLEDRLWCQDGQ

-P--ALTWDQRIQIAIDCARGLTYLHECP-EGPVVHRDIKPTNILLNGLLEAKLSDFGLSKII---ELDASHVS-----TEIKGTTGYLDPEYLI--LGQ
 |  .|.| ||. |..  |.|. .||.     |. |.|||. ||||   ...|..||||       .   ....       ..||| |. ||..    ||
CPPKPLSWHQRCSICWGTACGIQFLHQNHPCTPIIHGDIKSANILLDQHFTPKICDFGLHRFGHPASHKEKQTYTCMMTSHVRGTTWYMPPEFIRDPQGQ

LTEASDVYSFGIVLLQLMSGRKAIDNDTRVNRSIVEMVSTLFLHDNQ---GLS---------------------QLLDPRLDCDVPLPAFQKLAEVAHLC
||  .|||||||||| . .|..| ..| . .. ... .. .    ..    .|                      ..|.|   ..|    .... .|  |
LTKKTDVYSFGIVLLEVLTGCRAVYDDRPEHYYLKDLCEEIMEEWGHLDSCQSTLWVGVATDAWAAPRRMQIYEKFIDHRMP-PCPPNMEKEMCQCACCC

VQPRSYDRPSISEVLHDL
.  |   |... .|.  |
GHHRANRRCDMAWVMQQL
Kinase RLCK-OS3_b.AA Pkinase 293-561 20 2.7e-42 150.62 Pfam 1-293 (293) Show / Hide 
Range on Protein: 293-561
Range on HMM: 1-293/293
Sequence Identity: 20% (64 aa)

FSNASLLGEGSAGKVYIGQLPSG-KLVAVKRILKERKVETFYK------EVELLARIRHPNLTALLGYCRSKHVCLLVYEYMSNG----DLAQKLLR-KD
.   . .|.|| |.||...  .  |.||||.| |... . . .      |.....|..|||   |......|  . .| ||. .|    ||.  ... ..
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLF-DYISTWR

GPAL--TWDQRIQIAIDCARGLTYLHECPEGPVVHRDIKPTNILLNGLLEA----KLSDFGLSKIIELDASHVSTEIKGTTGYLDPEYLI-LGQLTEASD
. ..  .... . ..   .||| |.|..    ..|||.|| |||..   .     |..||||.| ...  ..  | . || .|. || .      . ..|
HGCFYFSEWECKFYMYQILRGLEYCHSM---GIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVD

VYSFGIVLLQLMSGRKAIDNDTRVNRSIVEMVSTLFLHD----NQGLSQLLDPRLDCDVPLPAF-----------------------QKLAEVAHLCVQP
..|.|..| ....||                  ..| ..    |    |... ....... . .                       . . ..   | ..
MWSCGCILYEMLCGR------------------PPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCK

RSYDRPSISEVLHD--L
  ..||.. ..|..  .
DPKKRPTAEQILQHPWF
Kinase RLCK-OS3_b.AA TKL-Unique 295-481 31 5.5e-42 145.81 In-house 1-218 (290) Show / Hide 
Range on Protein: 295-481
Range on HMM: 1-218/290
Sequence Identity: 31% (70 aa)

NASLLGEGSAGKVYIGQLPSGKLVAVKRILK-----ERKVETFYKEVELLARIR-HPNLTALLGYCR----SKHVCLLVYEYMSNGDLAQKLLR------
  ...|||..|.|| |  . |. ||.|.. .      .....|..|| .. ... |||.. . |||     .   . .| ||.. | |   | .      
FWNKIGEGGYGQVYKGKWR-GYPVAIKQFHPNEDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNNNNN

--KDGPALTWDQRIQIAIDCARGLTYLHECPEGPVVHRDIKPTNILLNGL-----LEAKLSDFGLSKIIELDASHVSTEI--------KGTTGYLDPEYL
  ..   |.. ||...|||.|.|. ||| | |.|. |||.|..|.|..       . .|..||||||.   .    ..|.        .|.. .. || |
NNNNNCKLNMQQRVKMAIDIAQGMYYLHHC-EPPIIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFRWMAPEVL

IL--GQLTEASDVYSFGIVL
     | .| ||||||||||
RMNFCQYSEKSDVYSFGIVL
Kinase RLCK-OS3_b.AA Dicty4 293-481 32 6.2e-41 134.36 In-house 1-207 (277) Show / Hide 
Range on Protein: 293-481
Range on HMM: 1-207/277
Sequence Identity: 32% (69 aa)

FSNASLLGEGSAGKVYIGQLPSGKLVAVKRI--LKER----KVETFYKEVELLARIRHPNLTALLGYCR----SKHVCLLVYEYMSNGDLAQKLLRK---
    ...|.|| |.|| |    || ||||    ...       . | |||.... |||||.  ..|.|      .  .. | |||. |.|. .||..   
INIEQRIGKGSFGEVYKGTW-RGKEVAVKKLNNHNQNFDENMLNEFRKEVHIMCKIRHPNICLFMGACTAPRSHPGKMCIVTEYMPKGNLY-SLLHDKPS

---DGPALTWDQRIQ---IAIDCARGLTYLHECPEGPVVHRDIKPTNILLNGLLEAKLSDFGLSKIIELDASHVS--TEIKGTTGYLDPEYLILGQLTEA
   .   | |  ...   .|.|.|||...||.|    ..|||.|. |.|    . .| .|||||...  . .|    .  .||...  || .     .|.
EQQQSIKLDWPLIKRAMRMAFDAARGMNWLHCC-NPVIIHRDLKSHNLLVDKNWRVKVCDFGLSQYMKKHEDHKDNQMTACGTPCWMAPEVMMHQPYNEK

SDVYSFGIVL
.|||||||||
ADVYSFGIVL
Kinase RLCK-OS3_b.AA TK 293-561 15 2e-36 119.06 In-house 1-486 (486) Show / Hide 
Range on Protein: 293-561
Range on HMM: 1-486/486
Sequence Identity: 15% (77 aa)

FSNASLLGEGSAG---KVYIGQLPSGK--------------------------LVAVKRILKE--RKVET--------------FYKEVELLARIR----
      ||||  |   .|| |.. ...                           |||| . ..     |               |..|.| ..  .    
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

-HPNLTALLGYCRSK------------HVCLLVYEYMSNGD----LAQKLL--RKDGPA-----------------------------------------
 |||.  |.|.|  .            . ...| |||..||    | . |   |...                                           
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

-------------------------------LTWDQRIQIAIDCARGLTYLHECP-EG--PVVHRDIKPTNILLNGLLE-----------AKLSDFG---
                               ||  |.. .. . |.|. |||... |.   .||||.   |.|..  .            .|..|||   
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSR

-----LSKIIELDASHVSTEIKGTTG-------------------------YLDPEYLI---------LGQLTEASDVYSFGIVLLQLMS-GRKAIDNDT
     |.. |. |   .... .||..                         .. || |           |  |..|||.|||...  ... |..    . 
QGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGM

RV--------NRSIVEMVSTL-------FLHDNQGLSQLLDPRLDCDV----PLPAFQ-----KLA-EVAHLCVQPRSYDRPSISEVLHDL
          |. ..|.. .        . . ..|    . .  .|         . .     ..  ..   | ..   |||. |.... |
SNQDVWKDGDNQEVMEYLRRGGRLCRSGL-N-EVGYRMRMPQPPHCPDWMRYRM-H-PPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL
Kinase RLCK-OS3_b.AA S_TKc 293-564 20 1.9e-35 125.02 SMART 1-231 (231) Show / Hide 
Range on Protein: 293-564
Range on HMM: 1-231/231
Sequence Identity: 20% (59 aa)

FSNASLLGEGSAGKVYIGQLPS-GKLVAVKRILKERKVETFYKEVELLARIRHPNLTALLGYCRSKHVCLLVYEYMSN--GDLAQKLLRKDGPA----LT
.    ..|.|. |||| ..  . |..||.|.|      |....|...| . .|||.  |...... .   .| ||...  ||| . . .. ..     ..
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-----EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFP

WDQRIQIAIDCARGLTYLHECPEGPVVHRDIKPTNILLNGLLEAKLSDFGLSKIIELDASHVSTEIKGTTGYLDPEYLILGQLTE-ASDVYSFGIVLLQL
  .   ..   ...| |.|.     ..|||.|| ||||.   . |..||||....        | . ||  |. || |   . .  ..|..|.|..|  .
E-HARFYMYQICCALEYCHSHG---IIHRDLKPENILLDE--HIKICDFGLARQL--------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEM

MSGRKAIDNDTRVNRSIVEMVSTLFLHDNQGLSQLLDPRLDCDVPLPAFQKLAEVAHLCVQPRSYDRPSISEVLH-D-----LELA
..|.   .        . ...                            . . .    | |    .||.. |.|. .      .  
LCGYPPFP----QMQMMFKKIG--------------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase RLCK-OS3_b.AA MLK 293-488 25 6.9e-35 118.49 In-house 1-233 (291) Show / Hide 
Range on Protein: 293-488
Range on HMM: 1-233/291
Sequence Identity: 25% (60 aa)

FSNASLLGEGSAGKVYIGQLPSGKL-----VAVKRIL--------KERKVETFYKEVELLARIRHPN----LTALLGYCRSK-HVCLLVYEYMSNGDLAQ
. .   .|.|| |||. |.   .|.     |||||.         ..   . | .|...|....|||      ...| | .  .  ..| ||...| |. 
IQFHEWIGSGSFGKVWKGRW-RNKDIVAKIVAVKRVRARIFDKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQPPCHFCIVMEYCEGGSLYN

KLLR-KDGPA-----------LTWDQRIQIAIDCARGLTYLHECPEGPVVHRDIKPTNILLN------GLLEAKLSDFGLSKIIELDASHVSTEIKGTTG
 |   .....            . |. ...| .||||. |||.    |..|||.|. |||.       . . .| .|||.|. .        .  .||  
VLHGARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHSMAPKPIIHRDLKSHNILIDEICHDMHHGTLKICDFGTSRDWHQMC-TNMMSNAGTYA

YLDPEYL---ILGQLTEASDVYSFGIVLLQLMSGR
.  || .     .. .|..||.|.|.|| ......
WMAPEVIQQFRCEKYSEKCDVWSWGVVLWEMLTRE
Kinase RLCK-OS3_b.AA STE 293-488 18 1.6e-33 115.78 In-house 1-265 (359) Show / Hide 
Range on Protein: 293-488
Range on HMM: 1-265/359
Sequence Identity: 18% (52 aa)

FSNASLLGEGSAGKVYIGQLP----------------SGKLVAVKRILKER-------------------KVETFYKEVELLARIR--HPNLTALLGYCR
. . . .|.|. |.|| .                   .|...|.|.. .|.                   ... . ||.... . .  |||    .|.. 
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

SK-------HVCLLVYEYMSNGDLAQKLLRKDGPALT------------WDQRIQIAIDCARG-LTYLHECPEGPVVHRDIKPTNILLNGLLEAKLSDFG
 .       . . .. |||..| | . . .| |.  .             .| . |. .. .| | |||.     ..|||||| ||||     .||.|||
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHH---IIHRDIKPANILL-----VKLCDFG

LSKIIELD--------------ASH-VSTEIKGTTGYLDPEYLIL------GQLTEASDVYSFGIVLLQLMSGR
...... .               .   .. . ||  .  || .        .. .. .|..|.|.... .  |.
VCGQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGK
Kinase RLCK-OS3_b.AA LRRK 293-488 23 3.2e-31 107.68 In-house 1-279 (351) Show / Hide 
Range on Protein: 293-488
Range on HMM: 1-279/351
Sequence Identity: 23% (66 aa)

FSNASLLGEGSAG-KVYIGQLPS---------------------------GKLVAVKRILKE------------------------------------RK
.   ...|.|. | .|| . . .                           .. ||.| ....                                    |.
LKIEEQIGRGGFGTFVYRAKWRGQPVHVCRMHQKMLQPYMYQGARNSYDMCQWVAIKKWNRDPMTIDNDCNNSNNNNNLNNNNSEQVEDMDQNHEDCCRA

VETFYKEVELLARIRHPNLTALLGYCRSKHVCLLVYEYMSNGDLAQKLL--RKDG-----PALTWDQRIQIAIDCARGLTYLHECPEGPVVHRDIKPTNI
  .| .|| .. . .|||.  |.|.| . . | .| ||...||| . |   ..||     . ..|  ...||.. |.|. ||| .   |..||| |. ||
FREFRHEVWIMSHLNHPNIVSLKGFCIH-PLC-MVMEYAPHGDLYHFLHNKKQDGFHFMKAHISWMLKLKIALQIAKGMEYLHSH-NPPIIHRDLKSPNI

LLNGL------------LEAKLSDFGLSKIIELDASHVSTEIKGTTGYLDPEYLILG-----QLTEASDVYSFGIVLLQLMSGR
||...              ||..|||.| .   . . |     |. |.. ||  |..     . || .|.||||..|  |....
LLWSSPQNHSPNYPNAHVCAKIADFGISRMFQCFHMGVAKGCVGNPGWMAPE--IMRYNGEEEYTEKVDCYSFGMILWELLTRQ
Kinase RLCK-OS3_b.AA Pkinase_Tyr 293-481 29 1.8e-30 103.79 Pfam 1-204 (270) Show / Hide 
Range on Protein: 293-481
Range on HMM: 1-204/270
Sequence Identity: 29% (62 aa)

FSNASLLGEGSAGKVYIGQLP-----SGKLVAVKRILKERKVET------FYKEVELLARI-RHPNLTALLGYCR-SKHV--CLLVYEYMSNGDLAQKLL
 .    ||||. |.|| | .       .  |||| . ||   .       | .|....  . .|||.  |.| |   .     ..| ||| .|||   | 
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR

RK--DGPALTWDQRIQIAIDCARGLTYLHECPEGPVVHRDIKPTNILLNGLLEAKLSDFGLSKIIELDASH-VSTE-----IKGTTGYLDPEYLILGQLT
..  |...||  . .|.... |.|. ||.. .    .|||.   |.|..  . .| .||||.. |. |    ....     || .     || .  |  |
KHREDKQPLTMKDLLQMCWQIAKGMEYLESKN---CIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWM----APECINYGKFT

EASDVYSFGIVL
..|||.|||...
TKSDVWSFGVLM
Kinase RLCK-OS3_b.AA TK-Unique 293-481 24 3e-30 101.55 In-house 1-229 (294) Show / Hide 
Range on Protein: 293-481
Range on HMM: 1-229/294
Sequence Identity: 24% (57 aa)

FSNASLLGEGSAGKVYIGQLPS-------GKLVAVKRILKERKVET---FYKEVELLARIR-HPNLTALLGYCRSKH-VCLLVYEYMSNGDLAQKLLRKD
. . ...|||. | |. |.. .        | ||||   ..   ..   | || ...  .  |||.  .||.| ..    ....||...|.| |..||. 
LEVGDVIGEGAFGQVWRGEVWGIWKHWDKQKCVAVKMLKDNATDTDKQDFLKEIQMMKELGDHPNIVQCLGCCTKSDEPWMIIMEYCPCGNL-QHYLRTC

GPA-------------------------LTWDQRIQIAIDCARGLTYLHECPEGPVVHRDIKPTNILLNGLLEAKLSDFGLSKIIELDASHVSTEIKGTT
.||                         ..  . ...|...|.|. ||.. ... .||||.   |.||.. ...|..|||... .. .  ..... .|..
RPAMRQHQTYGNLKFDFHHMPDKPRTEPISPKDLYHFAWQIACGMEYLASQRKK-IVHRDLCARNVLLTEDKVCKICDFGMARDVYTNGVYSMMCSQGRI

G--YLDPEYLI--LGQL-TEASDVYSFGIVL
   .. ||.|    |.  |. |||.|||...
PIRWMAPESLKCYHGMYHTTKSDVWSFGVLM
Kinase RLCK-OS3_b.AA ULK 293-481 21 1.7e-29 100.19 In-house 1-246 (329) Show / Hide 
Range on Protein: 293-481
Range on HMM: 1-246/329
Sequence Identity: 21% (55 aa)

FSNASLLGEGSAGKVYIGQ-LPS----GKLVAVKRIL----KERKVET--------FYKEVELLARIR--------HPNLTALLGYCRSKHV--CLLVYE
..    ||.|| |||| |    .    ...||.| |.    .. . |         . .|.... ..         |||   |. ......   . ...|
YCLNHCLGKGSFGKVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYIIME

YMSNGDLAQKLLRKDGPA---------LTWDQRIQIAIDCARGLTYLHECPEGPVVHRDIKPTNILLNGLL------------EAKLSDFGLSKIIELD-
|   ||| .... |...          |. .. ||. .. . |. .||.     ..|||||| |||..                .|..|||..| .. | 
YCNGGDL-EQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKH---NIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNDN

---ASHVSTE----IKGTTGYLDPEYLILGQ-----LTEA-SDVYSFGIVL
   .  ...     ..||  |  |. .. ||      ... .|..|.|...
MEQQMMMTCVNEKRLCGTPLYMAPQ-ILQGQGEQKPYYDYKCDIWSLGCIF
Kinase RLCK-OS3_b.AA TyrKc 293-561 24 6e-24 86.8 SMART 1-280 (280) Show / Hide 
Range on Protein: 293-561
Range on HMM: 1-280/280
Sequence Identity: 24% (75 aa)

FSNASLLGEGSAGKVYIGQLPSGKLVAVKRILKERKVETFYKEVELLARI--RHPNLTALLGYCRSK-------HVCLLVYEYMSNGDLAQKLLRKDGPA
 .    ||||  |.|| |..     |||| . ..  .| |..| ... ..  .|||. .|.|.|...       .  ..| |||..||| .. ||| .| 
ITLGKKLGEGAFGEVYKGTWK--IQVAVKMLKEDA-REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDL-KDYLRKHRPK

LTWDQRIQIAIDCARGLTYLHECPEGPVVHRDIKPTNILLNGLLEAKLSDFGLSKIIELD---ASHVSTEIKGTTG--YLD---------PEYLILGQLT
|.... ...... |.|  |||.    ...|||.   |.|..  . .| ||||||. |. |      .|.. . ...    .         || .  |  |
LCMKDLLSFCWQIACGMEYLHSK---NCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQG--ESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFT

EASDVYSFGIVLLQLMSGRKAIDNDT-----RVNRSIVEMVSTLFLHDNQGLSQLLDPRLDCDVPLP-----AFQKLAEVAHLCVQPRSYDRPSISEVLH
..|||.|||...  ... . .            |. ..| | . .         .  |  |.    |     . ... ..   | .    |||. ||. .
TKSDVWSFGVCMWEIFT-YGQQPYPGMIQQMMSNQEVIEYVKQGYR--------MPQPPNDY----PMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHE

DL
..
CF
Kinase RLCK-OS3_b.AA TK-Unique 550-561 41 0.048062 2.99 In-house 283-294 (294) Show / Hide 
Range on Protein: 550-561
Range on HMM: 283-294/294
Sequence Identity: 41% (5 aa)

DRPSISEVLHDL
.|||.....| |
ERPSFRQIKHRL
Kinase RLCK-OS3_b.AA TKL-Unique 550-561 50 0.082232 2.39 In-house 279-290 (290) Show / Hide 
Range on Protein: 550-561
Range on HMM: 279-290/290
Sequence Identity: 50% (6 aa)

DRPSISEVLHDL
.||| .|..| |
QRPSFDEIIHRL