Gene LRRXI (S.moellendorffii)

LRRXI

Species: S.moellendorffii
Alias: LRRXI
External Links:
Annotation:

Classification

Group: TKL
Family: IRAK
Subfamily: LRRXI

Sequence

Name Sequence Type Origin Length Description Download
LRRXI.AA Protein None 1002 None Fasta, JSON
LRRXI.NA RNA None 3009 None Fasta, JSON
LRRXI.kin_dom Protein Kinase Domain None 197 None Fasta, JSON

Protein domain

Protein domains of LRRXI.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
LRRNT_2 LRRXI.AA LRRNT_2 34-73 39 4.8e-12 42.02 Pfam 1-46 (46) Show / Hide 
Range on Protein: 34-73
Range on HMM: 1-46/46
Sequence Identity: 39% (18 aa)

TSDDGSVLLELRSNLT--DP-LGSLRGWTRS---TSYCSWQGIRCR
 .|||  ||...| |.  || .|.|. |. |   ...||| |. | 
HNDDGQALLAFKSSLNDSDPHHGVLSSWNPSSSDSDCCSWTGVTCD
LRR_1 LRRXI.AA LRR_1 78-100 29 27.511673 1.64 Pfam 1-26 (26) Show / Hide 
Range on Protein: 78-100
Range on HMM: 1-26/26
Sequence Identity: 29% (8 aa)

TVTGISLSGR---SLQGVISPA-IGRL
. . ..|||    .|.| |.|  .  |
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRRXI.AA LRR_1 102-124 37 0.002672 15.87 Pfam 1-26 (26) Show / Hide 
Range on Protein: 102-124
Range on HMM: 1-26/26
Sequence Identity: 37% (10 aa)

GLQALDLSR-N--SISGFIPSE-VTSC
 || ||||. |  ...| ||..   ..
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRRXI.AA LRR_1 126-148 37 0.009984 13.84 Pfam 1-26 (26) Show / Hide 
Range on Protein: 126-148
Range on HMM: 1-26/26
Sequence Identity: 37% (10 aa)

QLTDINLSQ-N--SLTGTIPQR-LDLL
.|. ..||  |  .|||.|| . .  |
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRRXI.AA LRR_1 150-172 40 0.002964 15.71 Pfam 1-26 (26) Show / Hide 
Range on Protein: 150-172
Range on HMM: 1-26/26
Sequence Identity: 40% (11 aa)

NLTSLRLFM-N--RLQGSIPAS-IGSL
||..| |   |  .|.|.|| | . .|
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRRXI.AA LRR_1 174-196 29 0.662483 7.38 Pfam 1-26 (26) Show / Hide 
Range on Protein: 174-196
Range on HMM: 1-26/26
Sequence Identity: 29% (8 aa)

LLTRLRVDD-N--ELDGFIPSE-IGNC
 |..| ... |   | | ||.. . |.
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRRXI.AA LRR_1 198-220 22 27.333799 1.65 Pfam 1-26 (26) Show / Hide 
Range on Protein: 198-220
Range on HMM: 1-26/26
Sequence Identity: 22% (6 aa)

SLTFFQVYN-N--RLRGGVPAT-IGRL
.|.   . . |  .| | .|   .  |
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRRXI.AA LRR_1 222-244 29 0.0059 14.65 Pfam 1-26 (26) Show / Hide 
Range on Protein: 222-244
Range on HMM: 1-26/26
Sequence Identity: 29% (8 aa)

RLTHLALYN-N--SLSGPLPRE-LGGC
.|.|| | . |  .|.| .| . . ..
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRRXI.AA LRR_1 246-268 25 0.04504 11.52 Pfam 1-26 (26) Show / Hide 
Range on Protein: 246-268
Range on HMM: 1-26/26
Sequence Identity: 25% (7 aa)

ALKRLTINR-N--LFQGQIPSE-LGRL
 |..| ... |   ..|.||.. .  |
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRRXI.AA LRR_1 270-292 33 0.032342 12.03 Pfam 1-26 (26) Show / Hide 
Range on Protein: 270-292
Range on HMM: 1-26/26
Sequence Identity: 33% (9 aa)

NLNEFQASSC---NFTGSLPVE-LGSL
|| .   |.|   |.||..| . . .|
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRRXI.AA LRR_1 294-316 29 0.013635 13.36 Pfam 1-26 (26) Show / Hide 
Range on Protein: 294-316
Range on HMM: 1-26/26
Sequence Identity: 29% (8 aa)

SLSSLDVSR-N--RLSGELPLG-LGST
.| .||.|. |  .|.|..| . . . 
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRRXI.AA LRR_1 319-341 37 0.002724 15.84 Pfam 1-26 (26) Show / Hide 
Range on Protein: 319-341
Range on HMM: 1-26/26
Sequence Identity: 37% (10 aa)

QMLSLNLSS-N--NITGSVPDS-FGAM
.  .|.||. |  |.||..|.| | ..
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRRXI.AA LRR_1 343-365 37 0.412383 8.11 Pfam 1-26 (26) Show / Hide 
Range on Protein: 343-365
Range on HMM: 1-26/26
Sequence Identity: 37% (10 aa)

TLDALDLSL-N--SFTGELPLR-IGLL
.|  ||||  |  ..||..| . .  |
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRRXI.AA LRR_1 367-386 42 0.008006 14.18 Pfam 1-26 (26) Show / Hide 
Range on Protein: 367-386
Range on HMM: 1-26/26
Sequence Identity: 42% (11 aa)

NLSVLSLSG-N--QFQGPLPP---AL
|| .|.||| |  ...| .||   .|
NLQHLDLSGCNCCNLTGHIPPSCFNL
LRR_1 LRRXI.AA LRR_1 391-413 25 0.047751 11.43 Pfam 1-26 (26) Show / Hide 
Range on Protein: 391-413
Range on HMM: 1-26/26
Sequence Identity: 25% (7 aa)

DLRVLNASN-N--RFSGGLPPR-LCSS
 |..|. |. |  ...| .||. . . 
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRRXI.AA LRR_1 415-436 33 0.03829 11.77 Pfam 1-26 (26) Show / Hide 
Range on Protein: 415-436
Range on HMM: 1-26/26
Sequence Identity: 33% (9 aa)

NLSLLDLSN-N--RIEGTLLT--VENC
||  ||||. |  ...|..      |.
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRRXI.AA LRR_1 438-459 33 0.001202 17.1 Pfam 1-26 (26) Show / Hide 
Range on Protein: 438-459
Range on HMM: 1-26/26
Sequence Identity: 33% (9 aa)

SLQTLVVSN-N--FISGSFPQ--FQSL
.||.| .|. |   ..|..|   | .|
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRRXI.AA LRR_1 460-481 29 3.007834 5.05 Pfam 1-26 (26) Show / Hide 
Range on Protein: 460-481
Range on HMM: 1-26/26
Sequence Identity: 29% (8 aa)

RLEVLDLSM-N--QMGGQLSL--SNEL
.|..||||  |  .. |...      |
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRRXI.AA LRR_1 483-505 29 0.015326 13.18 Pfam 1-26 (26) Show / Hide 
Range on Protein: 483-505
Range on HMM: 1-26/26
Sequence Identity: 29% (8 aa)

HLKSLLLGS-N--RFSGPMPND-FYRL
.|..| |.. |  ...|  |.. |  |
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRRXI.AA LRR_1 507-528 25 0.148773 9.68 Pfam 1-26 (26) Show / Hide 
Range on Protein: 507-528
Range on HMM: 1-26/26
Sequence Identity: 25% (7 aa)

VLEALNVSR-N--LFQGSLPT--LLSL
 |. |..|. |   ..|..|   . .|
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRRXI.AA LRR_1 530-552 37 0.000729 17.87 Pfam 1-26 (26) Show / Hide 
Range on Protein: 530-552
Range on HMM: 1-26/26
Sequence Identity: 37% (10 aa)

GLHTLDLSH-N--NISDTIPDY-FSTF
 | .||||. |  |....||.  |  .
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRRXI.AA LRR_1 554-576 37 0.000202 19.85 Pfam 1-26 (26) Show / Hide 
Range on Protein: 554-576
Range on HMM: 1-26/26
Sequence Identity: 37% (10 aa)

SLTVLDISS-N--SFSGPIPSS-LGEL
.|..||.|. |  ...| ||.| .  |
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRRXI.AA LRR_1 578-599 25 0.376545 8.25 Pfam 1-26 (26) Show / Hide 
Range on Protein: 578-599
Range on HMM: 1-26/26
Sequence Identity: 25% (7 aa)

SLDQFNFSN-N--QLSGEIPQ--ITLF
.|   ..|. |  .|.|.||   .  .
NLQHLDLSGCNCCNLTGHIPPSCF-NL
Kinase LRRXI.AA TKL 709-968 20 2.4e-50 173.58 In-house 1-364 (364) Show / Hide 
Range on Protein: 709-968
Range on HMM: 1-364/364
Sequence Identity: 20% (78 aa)

IGTGPYGSVFRGIFA-WE--------KILAVKVGRTEQ-----------------------DADDTKNTYYYTSAARKLNRIRHPNVVKLEDFLVYKGA-
|| | .| |..|..  |         |  |||. ....                       | .  ..       .. ..|.||||.|..  .  . .  
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

------------KIFLYEYMPNKSLAEALHRPSGPKLHWNTRYKIAVGAAQGLSYLHHQY-------SIVHCDIKSNNVLLDSAFG--------------
              . .||.|. || . ||        |. | ..| ..|.|..||| .         |.|.|.||.|.|.|. .               
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH--------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWC

ARIADVGLAKLIGDSRN-------------------LSCLNR-SFGYTAPEAA-------------------KVSQKADVYSFGVVLLELLTGKRPMMED
. |.| ||.. .  | |                    ..  . .... |||.                    . |.|.||||||.|| |.||..||  ..
CKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPYYDY

GTSLVS------WVRNSIADDQ---PLSDIVDP-ILRNVNGPFQEEISSVFKIALISTDPSPARRPSMKDIVEVL
. . .       .    ..|..   |. .|      . .  |      |. |..    |. |  |||...|.. |
PYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHH-K-M-CPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
Kinase LRRXI.AA TKL-Unique 705-899 27 2.1e-35 122.36 In-house 1-233 (290) Show / Hide 
Range on Protein: 705-899
Range on HMM: 1-233/290
Sequence Identity: 27% (66 aa)

DGNVIGTGPYGSVFRGIFAWEKILAVKVG-RTEQDADDTKNTYYYTSAARKLNRIR-HPNVVKLEDFLV----YKGAKIFLYEYMPNKSLAEALHR----
..|.||.| ||.|..|... ...  ..     ..  . ...     .  . ..... |||.|..  . .    | .  ..  ||.|  || . ||.    
FWNKIGEGGYGQVYKGKWRGYPVAIKQFHPNEDSSNEMMQE---FENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNNN

----PSGPKLHWNTRYKIAVGAAQGLSYLHHQYS-IVHCDIKSNNVLLDSA-----FGARIADVGLAKLIGDSRNLSCLN-----------RSFGYTAPE
    ..  || .. |.|.|  .|||. ||||    | |.|.|| |.|.|..     . ..|.|.||.|.  ...| . .|            || . |||
NNNNNNNCKLNMQQRVKMAIDIAQGMYYLHHCEPPIIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFN-SKINKMTNNEHKGTRNQTRCGSFRWMAPE

AAKV-----SQKADVYSFGVVLLELLTGKR------P
  .      |.|.||||||.|| |..|.|.      |
VLRMNFCQYSEKSDVYSFGIVLWEIATRKITKTYKKP
Kinase LRRXI.AA IRAK 703-905 32 4.7e-35 121.72 In-house 1-229 (317) Show / Hide 
Range on Protein: 703-905
Range on HMM: 1-229/317
Sequence Identity: 32% (75 aa)

FSDGNVIGTGPYGSVFRGIFAWEK-ILAVKVGRTEQDADDTKNTYYYTS---AARKLNRIRHPNVVKLEDFLVYKGAKIFLYEYMPNKSLAEALHRPSG-
|. .|.|| | .| |.|| .  .  | |||  . . |   ..      .     . ..|.||||.| |  .    .   . |.|||| ||   |.   | 
FHKDNRIGEGGFGCVYRGQWKNTTGIYAVKKLKEMADMSWNEHWQRFQQSYNELKVCCRCRHPNIVPLYGYCTERQCHCLVYPYMPNGSLEDRLWCQDGQ

-PK--LHWNTRYKIAVGAAQGLSYLHHQY---SIVHCDIKSNNVLLDSAFGARIADVGLAKLI---GDSRNLSC----LNRSFG---YTAPEAAK-----
 |   | | .| .|. |.| |. .||      .| | |||| |.|||  | . |.| ||.      ...   ..     .. .|   | .||. .     
CPPKPLSWHQRCSICWGTACGIQFLHQNHPCTPIIHGDIKSANILLDQHFTPKICDFGLHRFGHPASHKEKQTYTCMMTSHVRGTTWYMPPEFIRDPQGQ

VSQKADVYSFGVVLLELLTGKRPMMEDGT
 . | ||||||.||||.||| |..  |..
LTKKTDVYSFGIVLLEVLTGCRAVYDDRP
Kinase LRRXI.AA Pkinase 703-897 24 4.7e-26 93.19 Pfam 1-209 (293) Show / Hide 
Range on Protein: 703-897
Range on HMM: 1-209/293
Sequence Identity: 24% (53 aa)

FSDGNVIGTGPYGSVFRGIFAWE-KILAVKVGRTEQDADDTKNTYYYT-SAARKLNRIRHPNVVKLEDFLVYKGAKIFLYEYMPNK----SLAEALHRPS
.  | .|| | .|.|....   . || |||. . . .... |. .    | .. ..|..|||.|.| |.  .|.   .  ||...     .|.. ... .
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKR-HEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWR

GPKL--HWNTRYKIAVGAAQGLSYLHHQYSIVHCDIKSNNVLLDSAFGA----RIADVGLAKL--IGDSRNLSCLNRSFGYTAPEAAK----VSQKADVY
. ..   ...  ...   ..|| |.| . .|.|.|.|. |.|.|.        .|.| ||||.  .  .. .. .  . .| |||  .     ..|.|..
HGCFYFSEWECKFYMYQILRGLEYCHSM-GIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMW

SFGVVLLELLTGK
|.|..| |.|.|.
SCGCILYEMLCGR
Kinase LRRXI.AA TK 703-899 14 9.4e-25 79.25 In-house 1-394 (486) Show / Hide 
Range on Protein: 703-899
Range on HMM: 1-394/486
Sequence Identity: 14% (57 aa)

FSDGNVIGTGPYG---SVFRGIF----AWEK----------------------ILAVKVGRTEQDADDTKNTYY-------------YTSAARKLN--RI
   |...| | .|    |..|.      |.                         |||. . . .....    .               ... ...    
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

RHPNVVKLED-------------FLVYKGAKIFLYEYMPNKS----LAEALH--RPSGPK----------------------------------------
.|||.|.|               . | ..  . . ||||. .    | . |.  || . .                                        
HHPNIVRLYGVCTQGEPKPCFEVV-VHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQD

--------------------------------LHWNTRYKIAVGAAQGLSYLHHQ-Y----SIVHCDIKSNNVLLDSAFG-----------ARIADVG--
                                |.  ..  ... .|.|..||| . .     .|| |.   |.|...              ..||| |  
YDDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLS

------LAKLIGDSRNLSCLN-RSFGY--------------------------TAPEAAK------------VSQKADVYSFGVVLLELLT-GKRP
      ||. |... .    . .. |                           .|||. .             . | ||.||||.. |..| |. |
RQGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEP
Kinase LRRXI.AA RIPK 709-908 26 3.6e-23 75.79 In-house 1-236 (290) Show / Hide 
Range on Protein: 709-908
Range on HMM: 1-236/290
Sequence Identity: 26% (62 aa)

IGTGPYGSVFRGIFA-WEKILAVKVGR-TEQDAD-DTKNTYYYTSAARKLNRIRHPNVVKLEDFLVYKGAKIFLY------EYMPNKSLAEALHRPSG--
.| |  | ||.   . |   .|.|.    . ..  | .   |   .| .....|. ..|... |   . ..          |||.| ||.. ||. .   
VGGGGFGEVFKARHRHWGDWVAKKCKPCKHCHTHMDDQERMYQKEEAKHMHKLRCEHIVPIYGFCQCEEWDCDCKLYGIVMEYMENGSLWHFLHTKWPYQ

-PKLHWNTRYKIAVGAAQGLSYLHHQY-SIVHCDIKSNNVLLDSAFGARIADVGLAKLIGDSRNLS--C----------LNR--SFGYTAPEAAK-----
 . . |  |  . .  . |  ||| ..  | | | |  |.|.|. | . ||| |||.  . |   .  |          .||     | .||.       
HHPDPWPLRCRMIHEISCGMCYLHSMNPPIIHRDLKPENILVDNNFHVKIADFGLATWMMWSHSHQDRCNQREVYSMKSKNRWGTLSYMPPEHFRTDNKK

----VSQKADVYSFGVVLLELLTGKRPMMEDGTSLV
    |. | |||||..|. |.||.| |  .......
PIKVVTPKYDVYSFAIVMWEVLTQKHPYEDRKCMMM
Kinase LRRXI.AA MLK 703-899 25 2.3e-22 74.5 In-house 1-235 (291) Show / Hide 
Range on Protein: 703-899
Range on HMM: 1-235/291
Sequence Identity: 25% (60 aa)

FSDGNVIGTGPYGSVFRGIFAWEK----ILAVKVGRTEQDADDTKN---TYYYTSAARKLNRIRHPN-----VVKLEDFLVYKGAKIFLYEYMPNKSLAE
.    .|| |..|.|..| .  .     |.|||  |.. . |  .           .|.|....|||     .. .   | .      . ||... ||..
IQFHEWIGSGSFGKVWKGRWRNKDIVAKIVAVKRVRARIF-DKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQPPCHFCIVMEYCEGGSLYN

ALHR-PSGPK-----------LHWNTRYKIAVGAAQGLSYLHHQY--SIVHCDIKSNNVLLDS------AFGARIADVGLAKLIGDS-RNLSCLNRSFGY
 ||  .|..                   ..|.  |.|..||| .    |.| |.|| |.|.|          ..|.| |... . ..  |  .   .. .
VLHGARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHSMAPKPIIHRDLKSHNILIDEICHDMHHGTLKICDFGTSRDWHQMCTNMMSNAGTYAW

TAPEA------AKVSQKADVYSFGVVLLELLTGKRP
 |||.       |.| |.||.|.|||| |.||.. |
MAPEVIQQFRCEKYSEKCDVWSWGVVLWEMLTREVP
Kinase LRRXI.AA LRRK 781-900 29 7.1e-22 74.17 In-house 135-283 (351) Show / Hide 
Range on Protein: 781-900
Range on HMM: 135-283/351
Sequence Identity: 29% (44 aa)

EYMPNKSLAEALHRPS-GP------KLHWNTRYKIAVGAAQGLSYLHHQY-SIVHCDIKSNNVLL---D---------SAFGARIADVGLAK--LIGDSR
||.|. .| . || ..  .      .. |....|||.  | |. ||| .  .|.|.| || |.||   .          .  | ||| |.     .  . 
EYAPHGDLYHFLHNKKQDGFHFMKAHISWMLKLKIALQIAKGMEYLHSHNPPIIHRDLKSPNILLWSSPQNHSPNYPNAHVCAKIADFGISRMFQCFHMG

NLSCLNRSFGYTAPEAAKV------SQKADVYSFGVVLLELLTGK-RPM
 .. .   .|. |||  .       ..|.|.||||..| ||||.. .|.
VAKGCVGNPGWMAPEIMRYNGEEEYTEKVDCYSFGMILWELLTRQHHPF
Kinase LRRXI.AA Dicty4-Unclassified 807-902 37 1.4e-20 67.18 In-house 113-210 (263) Show / Hide 
Range on Protein: 807-902
Range on HMM: 113-210/263
Sequence Identity: 37% (37 aa)

KIAVGAAQGLSYLHHQYSIVHCDIKSNNVLLDSAFGARIADVGLAKLIGDSRNLSCLNRSFGYTAPEAAKV---SQKADVYSFGVVLLELLTGKRPMME
|.|   |||. .||    ..| |||| |.|.|  | ..||| |..  |    |.         ..||  .     ||.||||....| ||.||  | .|
KYAFDIAQGMQHLHTR-NFIHRDIKSSNILMDKHFNIKIADFGISRVIDFNFNMTTIAGTPKWESPECLMHESYNQKSDVYSYAMMLYELATGDEPYQE
Kinase LRRXI.AA Ciliate-E2 753-899 19 2.4e-19 63.05 In-house 71-295 (365) Show / Hide 
Range on Protein: 753-899
Range on HMM: 71-295/365
Sequence Identity: 19% (45 aa)

RKLN-------------RIRHPNVVKLEDFLV--YKGAKIFLYEYMPNKSLAE-----ALHRPSGPK----LHWNTRYKIAVGAAQ--------------
|..|             .. |||..|. ..     .    .  ||   ..| .      . |.. ..    . .. . .|    .|              
REINCFYKKINEKNILEQLNHPNIIKMYECFQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACII

-GLSYLHHQYSIVHCDIKSNNVLLDSAFGARIADVGLAKLIGDS---------RNLSCLNR------------------------SFGYTAPEAAK----
 .| ||| . .|.| ||| .|.|.       |.| ||.| . |.         ...    .                        . || |||  .    
LALEYLHSKNNIIHRDIKPENILF-----IKIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKY

--------VSQKADVYSFGVVLLELLTGKRP
         . |.|..|.||.| |.|.||.|
DNQQKQKGYDYKCDIWSLGVILYEMLFGKPP
Kinase LRRXI.AA S_TKc 703-971 19 6.3e-19 70.11 SMART 1-231 (231) Show / Hide 
Range on Protein: 703-971
Range on HMM: 1-231/231
Sequence Identity: 19% (56 aa)

FSDGNVIGTGPYGSVFRGIFAW-EKILAVKVGRTEQDADDTKNTYYYTSAARKLNRIRHPNVVKLEDFLVYKGAKIFLYEYMPN--KSLAEALHRPSGPK
.  ...|| | .|.|....     .| |.|. .               .  . | . .|||.||| |. .  .   .  ||...   .| . ...  ...
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHG

----LHWNTRYKIAVGAAQGLSYLHHQYSIVHCDIKSNNVLLDSAFGARIADVGLAKLIGDSRNLSCLNRSF----GYTAPEAAKVSQ-KADVYSFGVVL
    ..  .  ...   ...| |.| .  |.|.|.|  |.|||.     |.| |||...          ..|     | |||  . .  |.|..|.|..|
LRFPFPE-HARFYMYQICCALEYCHSH-GIIHRDLKPENILLDE--HIKICDFGLARQL----------TTFCGTPWYMAPEVLGYGKCKCDWWSCGCIL

LELLTGKRPMMEDGTSLVSWVRNSIADDQPLSDIVDPILRNVNGPFQEEISSVFKIALIST--DPSPARRPSMKDIVE------VLSRI
 |.|.|. |                     .  . . |.           |. .|  .|.   .  |..||.  .. .          .
YEMLCGYPPFP------------------QMQMMFKKIG-----------SPEAKD-FIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase LRRXI.AA TyrKc 703-968 21 1.2e-14 13.99 SMART 1-280 (280) Show / Hide 
Range on Protein: 703-968
Range on HMM: 1-280/280
Sequence Identity: 21% (64 aa)

FSDGNVIGTGPYGSVFRGIFAWEKILAVKVGRTEQDADDTKNTYYYTSAARKLNRI--RHPNVVKLEDFLVYK-------GAKIFLYEYMPNKSLAEALH
 . | ..| | .| |..|.       |||. . .             . || . ..  .|||.|.|    . .       .    . ||||. .| . |.
ITLGKKLGEGAFGEVYKGTWK--IQVAVKMLKEDA-------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR

RPSGPKLHWNTRYKIAVGAAQGLSYLHHQYSIVHCDIKSNNVLLDSAFGARIADVGLAKLIGDS-------RNLS-----CLN--RSFGYTAPEAA---K
.. .  | . .  .... .|.| .|||..  ..| |.   |.|... . ..|.| ||.. |.|           .     . .       .|||.    |
KHRPK-LCMKDLLSFCWQIACGMEYLHSK-NCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGK

VSQKADVYSFGVVLLELLT-GKRPMME------DGTSLVSWVRNSIADDQPLSDIVDPILRNVNGPFQEEISSVFKIALIST--DPSPARRPSMKDIVEV
 . | ||.||||.. |..| |. |  .      . . .. .|..    .|| .|   |.       |  . ..     ....  .  |. ||....|.| 
FTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDY--PMS------F-VCCPDEMYQ-IMKQCWHEDPEDRPTFSEIHEC

L
.
F
Kinase LRRXI.AA Dicty4 781-854 33 3.4e-11 33.77 In-house 82-164 (277) Show / Hide 
Range on Protein: 781-854
Range on HMM: 82-164/277
Sequence Identity: 33% (28 aa)

EYMPNKSLAEALHR------PSGPKLHWNTRYK---IAVGAAQGLSYLHH-QYSIVHCDIKSNNVLLDSAFGARIADVGLAKLI
||||  .|.. ||       .|  || | .. .   .|  ||.|. .||     |.| |.|| | | |  . . ..| ||....
EYMPKGNLYSLLHDKPSEQQQSI-KLDWPLIKRAMRMAFDAARGMNWLHCCNPVIIHRDLKSHNLLVDKNWRVKVCDFGLSQYM
Kinase LRRXI.AA Pkinase_Tyr 758-899 27 2.2e-10 35.78 Pfam 60-214 (270) Show / Hide 
Range on Protein: 758-899
Range on HMM: 60-214/270
Sequence Identity: 27% (43 aa)

I-RHPNVVKLEDFLVYKGAK---IFLYEYMPNKSLAEALHRP--SGPKLHWNTRYKIAVGAAQGLSYLHHQYSIVHCDIKSNNVLLDSAFGARIADVGLA
. .|||.|.|    . .|     .   ||||. .| . |...  ....|   .  ....  |.|..||. .  ..| |.   |.|... . ..|.| |||
LGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKN-CIHRDLAARNCLVTENNVVKICDFGLA

KLI---GDS-RNLSCLNRSFGYTAPE---AAKVSQKADVYSFGVVLLELLT-GKRP
..|   .   |  .        .|||     | . | ||.||||.. |..| |. |
RDIYNDDYYYRKRGGGKLPIKWMAPECINYGKFTTKSDVWSFGVLMWEIFTYGEQP
Kinase LRRXI.AA Dicty4 879-899 66 2.2e-07 20.88 In-house 196-216 (277) Show / Hide 
Range on Protein: 879-899
Range on HMM: 196-216/277
Sequence Identity: 66% (14 aa)

QKADVYSFGVVLLELLTGKRP
.|||||||| || |.||.. |
EKADVYSFGIVLWEILTRQEP
Kinase LRRXI.AA TK 955-968 35 0.001041 7.46 In-house 473-486 (486) Show / Hide 
Range on Protein: 955-968
Range on HMM: 473-486/486
Sequence Identity: 35% (5 aa)

PARRPSMKDIVEVL
|..||......| |
PEDRPTFSQLHEQL
Kinase LRRXI.AA MLK 952-968 41 0.001651 8.19 In-house 275-291 (291) Show / Hide 
Range on Protein: 952-968
Range on HMM: 275-291/291
Sequence Identity: 41% (7 aa)

DPSPARRPSMKDIVEVL
.. |..|||.. ||. |
NQDPHKRPSFRQIVQHL
Kinase LRRXI.AA Dicty4 952-970 33 0.002455 7.18 In-house 257-277 (277) Show / Hide 
Range on Protein: 952-970
Range on HMM: 257-277/277
Sequence Identity: 33% (7 aa)

DPSPARRPSMKDIVEV--LSR
|..| .|||.. |..   |  
DHDPQHRPSFEEIIQRRILEH
Kinase LRRXI.AA LRRK 955-970 43 0.003118 7.27 In-house 336-351 (351) Show / Hide 
Range on Protein: 955-970
Range on HMM: 336-351/351
Sequence Identity: 43% (7 aa)

PARRPSMKDIVEVLSR
| .||.. .||..|| 
PKKRPHFSQIVKRLSQ
Kinase LRRXI.AA Dicty4-Unclassified 954-968 40 0.007002 5.66 In-house 249-263 (263) Show / Hide 
Range on Protein: 954-968
Range on HMM: 249-263/263
Sequence Identity: 40% (6 aa)

SPARRPSMKDIVEVL
.| .||.| .|.. |
DPNKRPTMNQIIQYL
Kinase LRRXI.AA Pkinase_Tyr 952-968 35 0.015112 9.25 Pfam 254-270 (270) Show / Hide 
Range on Protein: 952-968
Range on HMM: 254-270/270
Sequence Identity: 35% (6 aa)

DPSPARRPSMKDIVEVL
.. |..||....|.| |
HYDPEDRPTFSEIHEQL
Kinase LRRXI.AA Dicty4 703-721 31 0.036611 3.21 In-house 1-19 (277) Show / Hide 
Range on Protein: 703-721
Range on HMM: 1-19/277
Sequence Identity: 31% (6 aa)

FSDGNVIGTGPYGSVFRGI
   .. ||.| .|.|..|.
INIEQRIGKGSFGEVYKGT
Kinase LRRXI.AA LRRK 703-722 28 0.079174 2.23 In-house 1-21 (351) Show / Hide 
Range on Protein: 703-722
Range on HMM: 1-21/351
Sequence Identity: 28% (6 aa)

FSDGNVIGTGPYG-SVFRGIF
.  .. || | .| .|.|...
LKIEEQIGRGGFGTFVYRAKW