Gene LRRIb-2 (S.moellendorffii)

LRRIb-2

Species: S.moellendorffii
Alias: LRRIb-2
External Links:
Annotation:

Classification

Group: TKL
Family: IRAK
Subfamily: LRRIb

Sequence

Name Sequence Type Origin Length Description Download
LRRIb-2.AA Protein None 453 None Fasta, JSON
LRRIb-2.NA RNA None 1362 None Fasta, JSON
LRRIb-2.kin_dom Protein Kinase Domain None 262 None Fasta, JSON

Protein domain

Protein domains of LRRIb-2.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase LRRIb-2.AA TKL 156-413 22 1e-64 221.34 In-house 1-364 (364) Show / Hide 
Range on Protein: 156-413
Range on HMM: 1-364/364
Sequence Identity: 22% (83 aa)

VGRGAFGPVFKA-VRP--------TGPVLAVKVLDVKSKQGG---------------------------REFQTEVLLLGRLHHRNLVNLVGYCAERGH-
.|.|.|| |.|.  |         || . |||.. ... .                              ..  |.... ||.| |.| ..||| . .. 
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

------------CMLVYEFMSGGNLAEILYNEERAALSWKLRVSVAHDISRGIEYLHDGAV-----PPVIHRDIKSSNILLDAMST--------------
            ...|.|...||.| ..|         | .|.. |.||.||..|||         ||.||||.||.|||.|   |              
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH--------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWC

AKVADFGLSKEMTFGVP--------------------TSAVKGTFGYVDPQYLLTN----------------VFTEKSDVYSFGILLFELITGRNPQQGL
.|..|||||..|.                        |. . ||...  |  |  .                 ..||.|||||||.|.|..|.. | ...
CKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPYYDY

LDYVKLAALGVEGADGWGELVDPRLEGHCN------------LQEFGQIASIAFRCVNEDPRHRPKMRDVSQWL
  .  ...  .   . .   .| .|   .              .   ...... .| ..||. || . .. ..|
PYMPMIFQD-P-FEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
Kinase LRRIb-2.AA Dicty4 151-347 32 6e-50 164.86 In-house 2-216 (277) Show / Hide 
Range on Protein: 151-347
Range on HMM: 2-216/277
Sequence Identity: 32% (70 aa)

NFTTLVGRGAFGPVFKAVRPTGPVLAVKVL----DVKSKQGGREFQTEVLLLGRLHHRNLVNLVGYCA----ERGHCMLVYEFMSGGNLAEILYN-----
|.. . |.|.|| |.|. .  |   |||.|    .. .     ||  || ... . | |.. . |.|     . | .. | |.|. |||...| .     
NIEQRIGKGSFGEVYKG-TWRGKEVAVKKLNNHNQNFDENMLNEFRKEVHIMCKIRHPNICLFMGACTAPRSHPGKMCIVTEYMPKGNLYSLLHDKPSEQ

EERAALSWKLRVS---VAHDISRGIEYLHDGAVPPVIHRDIKSSNILLDAMSTAKVADFGLSK----EMTFGVPTSAVKGTFGYVDPQYLLTNVFTEKSD
 ..  |.| |. .    | |. ||. .|| .  | .||||.||.|.| |.  ..||.|||||.    . ...  .....|| ... |  .  . ..||.|
QQSIKLDWPLIKRAMRMAFDAARGMNWLH-CCNPVIIHRDLKSHNLLVDKNWRVKVCDFGLSQYMKKHEDHKDNQMTACGTPCWMAPEVMMHQPYNEKAD

VYSFGILLFELITGRNP
||||||.|.|. |.  |
VYSFGIVLWEILTRQEP
Kinase LRRIb-2.AA TKL-Unique 152-344 32 1.7e-48 167.4 In-house 1-224 (290) Show / Hide 
Range on Protein: 152-344
Range on HMM: 1-224/290
Sequence Identity: 32% (74 aa)

FTTLVGRGAFGPVFKAVRPTGPVLAVKVLDVKSKQGGR---EFQTEVLLLGRLH-HRNLVNLVGYCA----ERGHCMLVYEFMSGGNLAEILY-------
|  ..|.|..|.|.|.. .. || |.|.. .....  .   ||  || .. .|| | |.| ..|||.      ... .| |...||.| . |        
FWNKIGEGGYGQVYKGKWRGYPV-AIKQFHPNEDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNNNNN

-NEERAALSWKLRVSVAHDISRGIEYLHDGAVPPVIHRDIKSSNILLDAM-----STAKVADFGLSKEMTFGVPTSAV----------KGTFGYVDPQYL
 |..   |....||. |.||..| .|||    | .||||.||||.|.|         .|..||||||  .    ...           .|.| .. |. |
NNNNNCKLNMQQRVKMAIDIAQGMYYLHHCEPP-IIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFRWMAPEVL

LT--NVFTEKSDVYSFGILLFELITG
    . ..|||||||||| | |..|.
RMNFCQYSEKSDVYSFGIVLWEIATR
Kinase LRRIb-2.AA IRAK 151-413 28 1.5e-46 160.99 In-house 2-317 (317) Show / Hide 
Range on Protein: 151-413
Range on HMM: 2-317/317
Sequence Identity: 28% (91 aa)

NFTTLVGRGAFGPVFKAVRPTGP-VLAVK----VLDVKSKQGGREFQT---EVLLLGRLHHRNLVNLVGYCAERGHCMLVYEFMSGGNLAEILYNEER--
.   . | |.|| |.....   . . |||    . |.. ..  ..||.   |. .. |..| |.| | |||.||.   |||..|..| |   |       
HKDNRIGEGGFGCVYRGQWKNTTGIYAVKKLKEMADMSWNEHWQRFQQSYNELKVCCRCRHPNIVPLYGYCTERQCHCLVYPYMPNGSLEDRLWCQDGQC

A--ALSWKLRVSVAHDISRGIEYLHDGA-VPPVIHRDIKSSNILLDAMSTAKVADFGLSK------EMTFGVP----TSAVKGTFGYVDPQYLL--TNVF
.  .|||  |.|..  ...||..||.     |.||.||||.|||||.  |.| .||||        ..  ..     || |.||  |  | ..   .   
PPKPLSWHQRCSICWGTACGIQFLHQNHPCTPIIHGDIKSANILLDQHFTPKICDFGLHRFGHPASHKEKQTYTCMMTSHVRGTTWYMPPEFIRDPQGQL

TEKSDVYSFGILLFELITGR-------NPQQGLLDYVKLAALGVEGADGWGE----------------------------LVDPRLEGHCNLQEFGQIAS
| |.||||||| | |..||.        . ..|.|..       | .. ||                             ..|.| .. |. ..   ...
TKKTDVYSFGIVLLEVLTGCRAVYDDRPEHYYLKDLCE------EIMEEWGHLDSCQSTLWVGVATDAWAAPRRMQIYEKFIDHRMPP-CPPNMEKEMCQ

IAFRCVNEDPRHRPKMRDVSQWL
 | .|. .  . |..|. | | |
CACCCGHHRANRRCDMAWVMQQL
Kinase LRRIb-2.AA LRRK 150-347 26 7.9e-44 151.92 In-house 1-282 (351) Show / Hide 
Range on Protein: 150-347
Range on HMM: 1-282/351
Sequence Identity: 26% (75 aa)

NNFTTLVGRGAFG-PVFKAVRPT---------------------------GPVLAVKVLDVKS--------KQGG-------------------------
  .  ..|||.|| .|..|                               .   |.|.... .           .                         
LKIEEQIGRGGFGTFVYRAKWRGQPVHVCRMHQKMLQPYMYQGARNSYDMCQWVAIKKWNRDPMTIDNDCNNSNNNNNLNNNNSEQVEDMDQNHEDCCRA

-REFQTEVLLLGRLHHRNLVNLVGYCAERGHCMLVYEFMSGGNLAEILYNEERAA-------LSWKLRVSVAHDISRGIEYLHDGAVPPVIHRDIKSSNI
 |||. || .. .|.| |.|.|.|.| .  ....| |... |.| . | |... .       .|| |.  .| .|..|.||||. . ||.|||| || ||
FREFRHEVWIMSHLNHPNIVSLKGFCIH--PLCMVMEYAPHGDLYHFLHNKKQDGFHFMKAHISWMLKLKIALQIAKGMEYLHS-HNPPIIHRDLKSPNI

LL---D---------AMSTAKVADFGLSKEMTFGVPT---SAVKGTFGYVDPQYLLTN---VFTEKSDVYSFGILLFELITGR-NP
||   .         |  .||.||||.|  | . ...   . . |..|.. |  .  |   ..|||.|.||||..|.||.|..  |
LLWSSPQNHSPNYPNAHVCAKIADFGISR-MFQCFHMGVAKGCVGNPGWMAPEIMRYNGEEEYTEKVDCYSFGMILWELLTRQHHP
Pkinase LRRIb-2.AA Pkinase 150-347 27 5e-43 153.23 Pfam 1-211 (293) Show / Hide 
Range on Protein: 150-347
Range on HMM: 1-211/293
Sequence Identity: 27% (59 aa)

NNFTTLVGRGAFGPVFKAVRPTGPV-LAVKVLDVKSKQGGREFQT-----EVLLLGRLHHRNLVNLVGYCAERGHCMLVYEFMSGG----NLAEILYNEE
  .   .|.|.|| |.|...   .   |||..... ..   . ||     |. .. ||.| | | | ... ...|. .| |.. ||     |....  ..
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKR-HEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWR

RAAL--SWKLRVSVAHDISRGIEYLHDGAVPPVIHRDIKSSNILLDAMSTA----KVADFGLSKE--MTFGVPTSAVKGTFGYVDPQYLL-TNVFTEKSD
. ..  |..   ...  | ||.||.|.     .||||.|..|||.|   .     |..||||.|      .. .. . || .|. |  ..  .  . |.|
HGCFYFSEWECKFYMYQILRGLEYCHS-M--GIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVD

VYSFGILLFELITGRNP
..|.|..|.|...|| |
MWSCGCILYEMLCGRPP
Kinase LRRIb-2.AA TK 150-413 14 1.8e-41 136.3 In-house 1-486 (486) Show / Hide 
Range on Protein: 150-413
Range on HMM: 1-486/486
Sequence Identity: 14% (73 aa)

NNFTTLVGRGAFG---PVFKA--------------------------VRPTGPVLAVKVLDVKSKQGGREFQT-----------------EVLLLG--RL
  .    |.|.||    |.|.                           . .    |||.|  .. .  .||.                  |  ..    .
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

HHRNLVNLVGYCAER------------GHCMLVYEFMSGGN----LAEILYNEE----------------------------------------------
|| |.|.|.|.| .             ...|.| |.|..|.    | . | .                                                
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

----------------------------RAALSWKLRVSVAHDISRGIEYLHDGAV---PPVIHRDIKSSNILLDAMST-----------AKVADFGLSK
                            .. |. . ..  ...|..| ||||.  .   . ..|||.   |.|..   .           .|.||||||.
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSR

E----MTFGVPTSAVKGTFG-------------------------------YVDPQYLLTNV---------FTEKSDVYSFGILLFELIT-GRNPQQGLL
.    ..  .. .    . .                               .  |  |...|         ||.||||.|||.|..|. | |. |  | .
QGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGM

DY---------VKLAALGVEG-----ADGWGE-----LVDPRLEGHC-----NLQEFG-----QIASI-AFRCVNEDPRHRPKMRDVSQWL
.            .  . ..|       | ..     .  |. .. .     .    .     ..  .   .| ..||..|| .... . |
SNQDVWKDGDNQEVMEYLRRGGRLCRS-G-LNEVGYRMRMPQPPHCPDWMRYRM-H-PPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL
Kinase LRRIb-2.AA Dicty4-Unclassified 151-360 33 5.5e-41 138.09 In-house 2-220 (263) Show / Hide 
Range on Protein: 151-360
Range on HMM: 2-220/263
Sequence Identity: 33% (75 aa)

NFTTLVGRGAFGPVFKAVRPTGPVLAVKVLDVKSKQGG----REFQTEVLLLGRLHHRNLVNLVGYC-AERGH---CMLVYEFMSGGNLAEILY---NEE
     .|.|.|  | | .   |   ||| .   . .       .|  || .|| . | ||| . ||| . | |    . | |||  ||| |.      | 
QIDQFIGKGHFSKVHKGNW-KGKDVAVKKFNENKFKFREEMIQDFKKEVEILGSIQHPNLVKCYGYCINPRSHKSTMCIVMEFMHKGNLFEVIHSKPSEQ

RAALSWKL--RVSVAHDISRGIEYLHDGAVPPVIHRDIKSSNILLDAMSTAKVADFGLSKEMTFGVPTSAVKGTFGYVDPQYLLTNVFTEKSDVYSFGIL
   ..      . .| || .|. .||      .|||||||||||.|    .|.||||.| .  |     .. ||     |  |    .. ||||||....
QQPIKLDDTLIIKYAFDIAQGMQHLHTRN---FIHRDIKSSNILMDKHFNIKIADFGISRVIDFNFNMTTIAGTPKWESPECLMHESYNQKSDVYSYAMM

LFELITGRNPQQGLLDYVKLAAL
|.||.||  | |.    . .| .
LYELATGDEPYQEIQSIMNAARS
Kinase LRRIb-2.AA CZAK 151-351 34 3.4e-40 139.87 In-house 2-225 (279) Show / Hide 
Range on Protein: 151-351
Range on HMM: 2-225/279
Sequence Identity: 34% (79 aa)

NFTTLVGRGAFGPVFKAVRPTGPVLAVKVLDVKSKQGGRE------FQTEVLLLGRLHHRNLVNLVGYCAERG--HCMLVYEFMSGGNLAEILYNEERAA
 |   .|.| || | ||.   | . |.| .   .     |      || ||  .  | | | |  .| | | |  |   | |.| || |   |   ..  
KFGQTIGQGFFGEVYKAYW-RGKDVAIKIIHRNQFRNKDENKEENMFQKEVSIMSKLCHPNCVQFLGACSEDGPNHHCIVMEWMGGGSLRRLL--TDHYF

LSWK---LRVSVAHDISRGIEYLHDGAVP-PVIHRDIKSSNILLDAMST-------------AKVADFGLS---KEMTFGVPTSAVKGTFGYVDPQYLLT
.      |. . | || ||  ||||   | |..|||  |.|||||   |             .|..|||||   .|  |   |... |   .  |     
YHKQNPHLQWNMAIDIARGMNYLHDNWKPNPILHRDLSSRNILLDHSYTPKNPVVSSRQDIICKINDFGLSREMMEQPFEM-TQTM-GCLCWMAPECFKG

NVFTEKSDVYSFGILLFELITGRNPQQGL
  .|||.||||||..|...||.. |.|..
ENYTEKVDVYSFGMILWCIITCDQPYQNM
Kinase LRRIb-2.AA MLK 150-300 26 1.2e-37 128.22 In-house 1-184 (291) Show / Hide 
Range on Protein: 150-300
Range on HMM: 1-184/291
Sequence Identity: 26% (48 aa)

NNFTTLVGRGAFGPVFKAVRPTGP----VLAVKVLD------VKSKQGGREFQTEVLLLGRLHHRN----LVNLVGYCAERGH-CMLVYEFMSGGNLAEI
 .| . .| |.|| |.|..         ..|||  .      ...    ..|..|. .| .| |.|     . ..| |.. ..   .| |...|| |...
IQFHEWIGSGSFGKVWKGRWRNKDIVAKIVAVKRVRARIFDKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQPPCHFCIVMEYCEGGSLYNV

LYNEER------------AALSWKLRVSVAHDISRGIEYLHDGAVPPVIHRDIKSSNILLDA------MSTAKVADFGLSKEMT
|....             .  .  . .. |....||..|||  |..|.||||.||.|||.|.        |.|..|||.|....
LHGARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHSMAPKPIIHRDLKSHNILIDEICHDMHHGTLKICDFGTSRDWH
Kinase LRRIb-2.AA S_TKc 150-413 22 9.4e-36 126.02 SMART 1-231 (231) Show / Hide 
Range on Protein: 150-413
Range on HMM: 1-231/231
Sequence Identity: 22% (63 aa)

NNFTTLVGRGAFGPVFKAVRPT-GPVLAVKVLDVKSKQGGREFQTEVLLLGRLHHRNLVNLVGYCAERGHCMLVYEFMSG--GNLAEILYNEERAA----
  .  ..|.|||| |.|..    | . |.|...       . .. |. .| . || |.|.| ... . .|  .| |...|  |.| ... .  |      
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFP

LSWKLRVSVAHDISRGIEYLHDGAVPPVIHRDIKSSNILLDAMSTAKVADFGLSKEMTFGVPTSAVKGTFGYVDPQYLLTNVFTE-KSDVYSFGILLFEL
..     .... | ...||.|.     .||||.| .|||||   . |..||||....      . . ||  |. |  |    ..  |.|..|.|..|.|.
FPE-HARFYMYQICCALEYCHS---HGIIHRDLKPENILLDE--HIKICDFGLARQL------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEM

ITGRNPQQGLLDYVKLAALGVEGADGWGELVDPRLEGHCNLQEFGQIASIAFRCVNEDPRHRPKMRDVSQ---------WL
..|. | .   .. ..  . .                        .  ..  .| . ||..||   .. |         |.
LCGYPPFP---QMQMMFKKIG----------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase LRRIb-2.AA LISK 155-300 32 3.2e-35 111.76 In-house 1-156 (296) Show / Hide 
Range on Protein: 155-300
Range on HMM: 1-156/296
Sequence Identity: 32% (52 aa)

LVGRGAFGPVFKAV-RPTGPVLAVKVLD-----VKSKQGGREFQTEVLLLGRLHHRNLVNLVGYCAE-RGHCMLVYEFMSGGNLAEILYNEE--RAALSW
  |.|.|| |.|   | || | |.| .      .. .   . .. || .. .| |.| |. .| | .  |. ..| |...||.| ..| ...     |.|
EIGKGFFGKVYKGTHRQTGQVMAIKMIHRQPNDPNDPEYQKFMLREVQMMKNLRHPNIVQFMGVCYHNDGQLHIVTEYINGGDLHQYLKDMDKHKIPLPW

KLRVSVAHDISRGIEYLHDGAVPPVIHRDIKSSNILLDAM----STAKVADFGLSKEMT
..||. | ||..| .|||.     .|||| || |.|..       ..||.|||. . |.
PQRVKIALDIACGMSYLHSMN---IIHRDLKSKNCLVRENDNNQWRIKVCDFGFARMMD
Kinase LRRIb-2.AA Pkinase_Tyr 151-299 29 1.7e-27 93.74 Pfam 2-161 (270) Show / Hide 
Range on Protein: 151-299
Range on HMM: 2-161/270
Sequence Identity: 29% (48 aa)

NFTTLVGRGAFGPVFKAVRP------TGPVLAVKVLDVKSKQGG---REFQTEVLLLGRL-HHRNLVNLVGYCA-ERGH--CMLVYEFMSGGNLAEILYN
 |    |.|||| |.|..        . || |||.|  .. .     ..|  |. ..  | || |.|.|.| |  ....   ..| |.| .|.| . | .
TFGKKLGEGAFGEVYKGTWKGDPDNTKIPV-AVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRK

E--ERAALSWKLRVSVAHDISRGIEYLHDGAVPPVIHRDIKSSNILLDAMSTAKVADFGLSKEM
   .. .|. |  .. ...|..| |||..      ||||.   |.|..   ..|..||||.. .
HREDKQPLTMKDLLQMCWQIAKGMEYLESKN---CIHRDLAARNCLVTENNVVKICDFGLARDI
Kinase LRRIb-2.AA TyrKc 150-413 24 1e-26 95.99 SMART 1-280 (280) Show / Hide 
Range on Protein: 150-413
Range on HMM: 1-280/280
Sequence Identity: 24% (74 aa)

NNFTTLVGRGAFGPVFKAVRPTGPVLAVKVLDVKSKQGGREFQTEVLLLGRL--HHRNLVNLVGYCAER-------GHCMLVYEFMSGGNLAEIL-YNEE
  .    |.|||| |.|..    .| |||.|   .    ..|  |  .. .|  || |.|.|.|.| .        .  |.| |.|..|.| . | ....
ITLGKKLGEGAFGEVYKGTWK-IQV-AVKMLKEDA---REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRP

RAALSWKLRVSVAHDISRGIEYLHDGAVPPVIHRDIKSSNILLDAMSTAKVADFGLSKEMTFG----VPTSAVKGTFGYVDPQ----------YLLTNVF
.  |..|  .| ...|..| ||||.    ..||||.   |.|...  |.|..|||||.. . .    . ..  . . .                . ...|
K--LCMKDLLSFCWQIACGMEYLHSK---NCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKF

TEKSDVYSFGILLFELIT-GRNPQQGL----LDYVKLAALGVEGADGWGELVDPRLEGHCNLQE------FGQIASIAFRCVNEDPRHRPKMRDVSQWL
|.||||.|||....|. | |  |  |     ..   . ..  .|         |. . ..   .         . .|  .| .|||  || .... . .
TTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQG------YRMPQPPNDY---PMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase LRRIb-2.AA Pkinase_Tyr 320-351 44 4e-10 34.91 Pfam 186-219 (270) Show / Hide 
Range on Protein: 320-351
Range on HMM: 186-219/270
Sequence Identity: 44% (15 aa)

LLTNVFTEKSDVYSFGILLFELIT-GRNP-QQGL
. ...||.||||.|||.|..|..| |. |  .|.
INYGKFTTKSDVWSFGVLMWEIFTYGEQPTYPGM
Kinase LRRIb-2.AA MLK 325-347 43 3.4e-08 24.65 In-house 213-235 (291) Show / Hide 
Range on Protein: 325-347
Range on HMM: 213-235/291
Sequence Identity: 43% (10 aa)

FTEKSDVYSFGILLFELITGRNP
..||.||.|.|..| |..|.. |
YSEKCDVWSWGVVLWEMLTREVP
Kinase LRRIb-2.AA LISK 326-347 50 8.4e-08 21.21 In-house 217-238 (296) Show / Hide 
Range on Protein: 326-347
Range on HMM: 217-238/296
Sequence Identity: 50% (11 aa)

TEKSDVYSFGILLFELITGRNP
.|..||.||||.| |.||....
DESCDVFSFGIVLCEIITRVKA
Kinase LRRIb-2.AA LISK 391-413 39 0.000782 8.11 In-house 274-296 (296) Show / Hide 
Range on Protein: 391-413
Range on HMM: 274-296/296
Sequence Identity: 39% (9 aa)

IAFRCVNEDPRHRPKMRDVSQWL
..|.|.. ||. ||.  .. |||
LCFDCCKYDPKNRPSFKEIVQWL
Kinase LRRIb-2.AA MLK 394-413 45 0.001567 8.27 In-house 272-291 (291) Show / Hide 
Range on Protein: 394-413
Range on HMM: 272-291/291
Sequence Identity: 45% (9 aa)

RCVNEDPRHRPKMRDVSQWL
.| |.||. ||..| . | |
QCWNQDPHKRPSFRQIVQHL
Kinase LRRIb-2.AA Dicty4-Unclassified 395-413 42 0.002575 7.17 In-house 245-263 (263) Show / Hide 
Range on Protein: 395-413
Range on HMM: 245-263/263
Sequence Identity: 42% (8 aa)

CVNEDPRHRPKMRDVSQWL
|  .||. || | .. | |
CWHNDPNKRPTMNQIIQYL
Kinase LRRIb-2.AA Dicty4 394-415 33 0.089302 1.9 In-house 254-277 (277) Show / Hide 
Range on Protein: 394-415
Range on HMM: 254-277/277
Sequence Identity: 33% (8 aa)

RCVNEDPRHRPKMRDVSQW--LSR
.| ..|| ||| .  ..|   |  
WCWDHDPQHRPSFEEIIQRRILEH
Kinase LRRIb-2.AA LRRK 395-415 33 0.214048 0.68 In-house 331-351 (351) Show / Hide 
Range on Protein: 395-415
Range on HMM: 331-351/351
Sequence Identity: 33% (7 aa)

CVNEDPRHRPKMRDVSQWLSR
| ..||. ||.. .. . || 
CWQHDPKKRPHFSQIVKRLSQ
Kinase LRRIb-2.AA Pkinase_Tyr 394-413 30 4.987365 0.72 Pfam 251-270 (270) Show / Hide 
Range on Protein: 394-413
Range on HMM: 251-270/270
Sequence Identity: 30% (6 aa)

RCVNEDPRHRPKMRDVSQWL
.| ..|| .|| .... . |
QCWHYDPEDRPTFSEIHEQL