Gene LRR8_j-1 (S.moellendorffii)

LRR8_j-1

Species: S.moellendorffii
Alias: LRR8_j-1
External Links:
Annotation:

Classification

Group: TKL
Family: IRAK
Subfamily: LRR8

Sequence

Name Sequence Type Origin Length Description Download
LRR8_j-1.AA Protein None 1032 None Fasta, JSON
LRR8_j-1.NA RNA None 3099 None Fasta, JSON
LRR8_j-1.kin_dom Protein Kinase Domain None 216 None Fasta, JSON

Protein domain

Protein domains of LRR8_j-1.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
LRRNT_2 LRR8_j-1.AA LRRNT_2 27-67 36 2.3e-12 43.07 Pfam 1-46 (46) Show / Hide 
Range on Protein: 27-67
Range on HMM: 1-46/46
Sequence Identity: 36% (17 aa)

GSEEVAALLGVKELLV--DE-FGHTNDWSASD--SSPCSWTGIQCD
 .....|||  |  |.  |  .|   .|..|.  |..|||||. ||
HNDDGQALLAFKSSLNDSDPHHGVLSSWNPSSSDSDCCSWTGVTCD
LRR_1 LRR8_j-1.AA LRR_1 96-118 33 0.335006 8.43 Pfam 1-26 (26) Show / Hide 
Range on Protein: 96-118
Range on HMM: 1-26/26
Sequence Identity: 33% (9 aa)

HLVNISLEQ-N--NLAGPLPPE-LSLL
.|  ..|   |  || | .||. .  |
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRR8_j-1.AA LRR_1 120-142 25 0.031924 12.05 Pfam 1-26 (26) Show / Hide 
Range on Protein: 120-142
Range on HMM: 1-26/26
Sequence Identity: 25% (7 aa)

RLRFLNISH-N--NF-GYGFPAN-LSAI
.|. |..|. |  |. |. .| . . . 
NLQHLDLSGCNCCNLTGH-IPPSCF-NL
LRR_1 LRR8_j-1.AA LRR_1 144-166 33 0.007551 14.27 Pfam 1-26 (26) Show / Hide 
Range on Protein: 144-166
Range on HMM: 1-26/26
Sequence Identity: 33% (9 aa)

TLEVLDTYN-N--NFSGPLPPE-LGAL
.|..||  . |  |..| .||. . .|
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRR8_j-1.AA LRR_1 168-190 37 0.006378 14.53 Pfam 1-26 (26) Show / Hide 
Range on Protein: 168-190
Range on HMM: 1-26/26
Sequence Identity: 37% (10 aa)

SIRHLHLGG-S--YFSGAIPPE-LGNL
...||.|.|     ..| |||. . ||
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRR8_j-1.AA LRR_1 192-214 51 5.2e-05 21.93 Pfam 1-26 (26) Show / Hide 
Range on Protein: 192-214
Range on HMM: 1-26/26
Sequence Identity: 51% (14 aa)

TLRYLALSG-N--SLTGRIPPE-LGNL
.|..| ||| |  .||| |||. . ||
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRR8_j-1.AA LRR_1 216-239 29 1.003843 6.74 Pfam 1-26 (26) Show / Hide 
Range on Protein: 216-239
Range on HMM: 1-26/26
Sequence Identity: 29% (8 aa)

ELEELYLGYYN--EFEGGIPRE-IGKL
 |..|.|.. |   ..| || . . .|
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRR8_j-1.AA LRR_1 241-263 44 0.001141 17.18 Pfam 1-26 (26) Show / Hide 
Range on Protein: 241-263
Range on HMM: 1-26/26
Sequence Identity: 44% (12 aa)

NLVRIDLGFC---GLTGRIPAE-IGNL
|| ..||. |    ||| || . . ||
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRR8_j-1.AA LRR_1 265-287 33 3.188842 4.96 Pfam 1-26 (26) Show / Hide 
Range on Protein: 265-287
Range on HMM: 1-26/26
Sequence Identity: 33% (9 aa)

RLDSIFLQI-N--NLSGPIPAE-IGLL
.| .. |.  |  ||.| || . .  |
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRR8_j-1.AA LRR_1 289-311 40 0.001194 17.11 Pfam 1-26 (26) Show / Hide 
Range on Protein: 289-311
Range on HMM: 1-26/26
Sequence Identity: 40% (11 aa)

ALKSLDLSN-N--LLSGPIPDE-LAML
 |..||||. |   |.| ||.. .  |
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRR8_j-1.AA LRR_1 313-335 33 0.26517 8.79 Pfam 1-26 (26) Show / Hide 
Range on Protein: 313-335
Range on HMM: 1-26/26
Sequence Identity: 33% (9 aa)

SIALVNLFR-N--RLTGSIPSF-FGDL
..   .| . |  .|||.||.  |  |
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRR8_j-1.AA LRR_1 337-359 44 0.00765 14.25 Pfam 1-26 (26) Show / Hide 
Range on Protein: 337-359
Range on HMM: 1-26/26
Sequence Identity: 44% (12 aa)

NLEVLQLWA-N--NLTGSIPPQ-LGQA
||..| |   |  ||||.|||  . . 
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRR8_j-1.AA LRR_1 386-408 33 0.036827 11.83 Pfam 1-26 (26) Show / Hide 
Range on Protein: 386-408
Range on HMM: 1-26/26
Sequence Identity: 33% (9 aa)

ALQVLILYG-N--QIGGALPES-LGQC
 ||.| | | |  .. | .|.| . ..
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRR8_j-1.AA LRR_1 362-385 33 0.084012 10.56 Pfam 1-26 (26) Show / Hide 
Range on Protein: 362-385
Range on HMM: 1-26/26
Sequence Identity: 33% (9 aa)

SLMTVDLSS-N--SLSGSIPDKICWGG
.| . |||. |  .|.|.||. .. . 
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRR8_j-1.AA LRR_1 410-432 29 0.335006 8.43 Pfam 1-26 (26) Show / Hide 
Range on Protein: 410-432
Range on HMM: 1-26/26
Sequence Identity: 29% (8 aa)

TLVRVRLGH-N--QLTGGLPKN-TLGL
.| .  |.. |  .||| .|..   .|
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRR8_j-1.AA LRR_1 458-480 44 0.003794 15.33 Pfam 1-26 (26) Show / Hide 
Range on Protein: 458-480
Range on HMM: 1-26/26
Sequence Identity: 44% (12 aa)

ELELLDLSQ-N--RLRGSIPRA-IGNL
 |. ||||  |  .| |.||   . ||
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRR8_j-1.AA LRR_1 482-504 37 0.015527 13.16 Pfam 1-26 (26) Show / Hide 
Range on Protein: 482-504
Range on HMM: 1-26/26
Sequence Identity: 37% (10 aa)

NLKNLLLGD-N--RISGRIPAS-IGML
||. | |.. |  ...| || | .  |
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRR8_j-1.AA LRR_1 506-528 37 0.003122 15.63 Pfam 1-26 (26) Show / Hide 
Range on Protein: 506-528
Range on HMM: 1-26/26
Sequence Identity: 37% (10 aa)

QLSVLDASG-N--AISGEIPRS-IGSC
.| .|| || |   ..|.|| | . ..
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRR8_j-1.AA LRR_1 530-552 37 0.007123 14.36 Pfam 1-26 (26) Show / Hide 
Range on Protein: 530-552
Range on HMM: 1-26/26
Sequence Identity: 37% (10 aa)

RLSSVDLSR-N--QLVGAIPGE-LAQL
.| . |||. |  .|.| || . . .|
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRR8_j-1.AA LRR_1 554-576 29 0.337189 8.42 Pfam 1-26 (26) Show / Hide 
Range on Protein: 554-576
Range on HMM: 1-26/26
Sequence Identity: 29% (8 aa)

ALDALNVSR-N--GLSGEIPRE-LEEA
 |  |..|. |   |.|.|| . .   
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRR8_j-1.AA LRR_1 578-602 32 26.120429 1.72 Pfam 1-26 (26) Show / Hide 
Range on Protein: 578-602
Range on HMM: 1-26/26
Sequence Identity: 32% (9 aa)

ALTSADFSY-N--RLFGPIPSQGQFGFF
 |.. |.|. |  .| | ||.   |  .
NLQHLDLSGCNCCNLTGHIPPS-CF-NL
Kinase LRR8_j-1.AA TKL 718-944 25 2.6e-62 213.35 In-house 1-312 (364) Show / Hide 
Range on Protein: 718-944
Range on HMM: 1-312/364
Sequence Identity: 25% (82 aa)

IGRGGSGTVYKAMMRS---------GELVAVKRLASCPVNSGKRSS---------------GSRSSHDDFGFSAEVQTLGKIRHMNIVKLLGFCSNHET-
||.||.|.|||.  |          |. ||||.. |  ...  ..|                  .|.  | .  |.  . ..|| |||...|.| . .  
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

------------NLLVYEYMPNGSLGEVLHGVGTKACPVLDWETRYKVAVQAANGLCYLHHDCS-----PLIVHRDVKSNNILLDSNLR-----------
              .|.||.|.||| ..||           |. | . | ..| |..||| .       | |.||| ||.|||.|.|..           
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH-----------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNA

---AHVADFGLAKLFQGSDKSESMSS-----------------VAGSYGYIAPEYA-----YT-----------LKVNEKSDIYSFGVVLLELVTGRRPI
   . ..||||.. ...| ... ...                 . |.... |||       ||           .. .||.|.||||.|| |..|..|| 
DWCCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPY

E-PGYGDEI------DIVKWVRK
. ..| ..|      .. ..| .
YDYPYMPMIFQDPFEEMFMMVCD
Kinase LRR8_j-1.AA IRAK 713-927 33 1.4e-56 194.32 In-house 2-223 (317) Show / Hide 
Range on Protein: 713-927
Range on HMM: 2-223/317
Sequence Identity: 33% (77 aa)

SEDNVIGRGGSGTVYKAMMRSGE-LVAVKRLASCPVNSGKRSSGSRSSHDDFGFS--AEVQTLGKIRHMNIVKLLGFCSNHETNLLVYEYMPNGSLGEVL
..||.|| || |.||.. ..  .  .|||.|        .  . |  .|. .. .   |.... ..|| ||| |.|.|.  .   |||.|||||||   |
HKDNRIGEGGFGCVYRGQWKNTTGIYAVKKLK-------EMADMSWNEHWQRFQQSYNELKVCCRCRHPNIVPLYGYCTERQCHCLVYPYMPNGSLEDRL

HGVGTKACP-VLDWETRYKVAVQAANGLCYLHHDCS--PLIVHRDVKSNNILLDSNLRAHVADFGLAKL--FQGSDKSESM-----SSVAGSYGYIAPEY
.. ..   |  | | .| ...  .|.|. .|| . .  |.| |.|.|| ||||| .. .  .||||.    . .. .. .      | | |.  | .||.
WCQDGQCPPKPLSWHQRCSICWGTACGIQFLHQNHPCTPII-HGDIKSANILLDQHFTPKICDFGLHRFGHPASHKEKQTYTCMMTSHVRGTTWYMPPEF

AY--TLKVNEKSDIYSFGVVLLELVTGRRP
 .  . .   |.|.||||.||||..||.|.
IRDPQGQLTKKTDVYSFGIVLLEVLTGCRA
Kinase LRR8_j-1.AA MLK 712-927 30 2.4e-45 155.25 In-house 1-235 (291) Show / Hide 
Range on Protein: 712-927
Range on HMM: 1-235/291
Sequence Identity: 30% (73 aa)

LSEDNVIGRGGSGTVYKAMMRSGE----LVAVKRLASCPVNSGKRSSGSRSSHDDFGFSAEVQTLGKIRHMN----IVKLLGFCSNHETN-LLVYEYMPN
. .  .|| |..| |.|. .|  .     ||||| .. .  ... .. ..       |  |.  | ...| |    |....| |.... . ..| ||...
IQFHEWIGSGSFGKVWKGRWRNKDIVAKIVAVKRVRARIFDKSDTYCEQWD------FEMECRHLRILSHPNNHPCIIQFYGVCLQPPCHFCIVMEYCEG

GSLGEVLHGVGTKACP---------VLDWETRYKVAVQAANGLCYLHHDCSPLIVHRDVKSNNILLDS------NLRAHVADFGLAKLFQGSDKSESMSS
||| .||||  .|  .         | | .   . |.| |.|. ||| .  ..|.||| || |||.|       .. . ..|||... .. ..  . | |
GSLYNVLHGARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHSMAPKPIIHRDLKSHNILIDEICHDMHHGTLKICDFGTSRDWHQMC--TNMMS

VAGSYGYIAPEY---AYTLKVNEKSDIYSFGVVLLELVTGRRP
 ||.| . |||    .   |..||.|..|.|||| |..|.. |
NAGTYAWMAPEVIQQFRCEKYSEKCDVWSWGVVLWEMLTREVP
Pkinase LRR8_j-1.AA Pkinase 712-925 26 1.1e-43 155.48 Pfam 1-209 (293) Show / Hide 
Range on Protein: 712-925
Range on HMM: 1-209/293
Sequence Identity: 26% (61 aa)

LSEDNVIGRGGSGTVYKAMMRSGEL-VAVKRLASCPVNSGK------RSSGSRSSHDDFGFSAEVQTLGKIRHMNIVKLLGFCSNHETNLLVYEYMPNG-
.    .||.|..|.|||.. .. .  ||||..  .  .|.|      .              .|.| . ...| |||.|.... ..    .| ||...| 
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRL--------------SEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGL

---SLGEVLHGVGTKACPVL--DWETRYKVAVQAANGLCYLHHDCSPLIVHRDVKSNNILLDSNLRA----HVADFGLAKLFQGSDKSESMSSVAGSYGY
   .| .....   ..  ..  ....  ... | . || |.|      |.|||.|. |||.|.|       ...||||||.|.   ... |....|...|
YVMDLFDYIST---WRHGCFYFSEWECKFYMYQILRGLEYCHSM---GIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD-Y-NNS-MTTFCGTPWY

IAPEYAY-TLKVNEKSDIYSFGVVLLELVTGR
.|||      .   |.|..|.|..| |...||
MAPEVIRGGQYYGPKVDMWSCGCILYEMLCGR
Kinase LRR8_j-1.AA TKL-Unique 716-927 33 5.8e-42 145.74 In-house 3-233 (290) Show / Hide 
Range on Protein: 716-927
Range on HMM: 3-233/290
Sequence Identity: 33% (80 aa)

NVIGRGGSGTVYKAMMRSGELVAVKRLASCPVNSGKRSSGSRSSHDDFGFSAEVQTLGKIR-HMNIVKLLGFCS----NHETNLLVYEYMPNGSLGEVLH
|.||.||.|.|||.. | |. ||.|...       . .. | .. ..  |. || .. |.. | |||.. |.|           .| ||.| ||| .|||
NKIGEGGYGQVYKGKWR-GYPVAIKQFH-------PNEDSSNEMMQE--FENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLH

-----GVGTKACPVLDWETRYKVAVQAANGLCYLHHDCSPLIVHRDVKSNNILLDSN-----LRAHVADFGLAKLFQGSDKSESM-------SSVAGSYG
         .    |... |.| | ..| |..||||   | | ||| || |.|.|.|     ... ..||||.|.   ..|. .        ... ||. 
QNNNNNNNNNNNCKLNMQQRVKMAIDIAQGMYYLHHCEPP-IIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFR

YIAPEYAYT--LKVNEKSDIYSFGVVLLELVTGRR------P
..|||       . .||||.||||.|| |..|. .      |
WMAPEVLRMNFCQYSEKSDVYSFGIVLWEIATRKITKTYKKP
Kinase LRR8_j-1.AA LRRK 712-927 28 6.4e-41 142.27 In-house 1-282 (351) Show / Hide 
Range on Protein: 712-927
Range on HMM: 1-282/351
Sequence Identity: 28% (82 aa)

LSEDNVIGRGGSG-TVYKAMMRS---------------------------GELVAVKRLASCP------VNSGKRSSG------------------SRSS
| . . |||||.| .||.| .|.                           .. ||.| .  .|       |    |..                  ....
LKIEEQIGRGGFGTFVYRAKWRGQPVHVCRMHQKMLQPYMYQGARNSYDMCQWVAIKKWNRDPMTIDNDCN---NSNNNNNLNNNNSEQVEDMDQNHEDC

HDDFG-FSAEVQTLGKIRHMNIVKLLGFCSNHETNLLVYEYMPNGSLGEVLH---GVG---TKACPVLDWETRYKVAVQAANGLCYLHHDCSPLIVHRDV
.  |  |  ||  . . .| |||.|.||| .. .  .| ||.|.|.| ..||     |    |  ....| ...|.|.| | |. || |...| |.||| 
CRAFREFRHEVWIMSHLNHPNIVSLKGFCIHPLC--MVMEYAPHGDLYHFLHNKKQDGFHFMK--AHISWMLKLKIALQIAKGMEYL-HSHNPPIIHRDL

KSNNILL---D---------SNLRAHVADFGLAKLFQGSDKSESMSSVAGSYGYIAPEYAY---TLKVNEKSDIYSFGVVLLELVTGR-RP
|| ||||   .          .  |..||||.  .|  .....  . . |  |. |||      .   .||.|.||||..| ||.|.. .|
KSPNILLWSSPQNHSPNYPNAHVCAKIADFGISRMF-QCFHMGVAKGCVGNPGWMAPEIMRYNGEEEYTEKVDCYSFGMILWELLTRQHHP
Kinase LRR8_j-1.AA S_TKc 712-992 22 3.2e-39 137.55 SMART 1-231 (231) Show / Hide 
Range on Protein: 712-992
Range on HMM: 1-231/231
Sequence Identity: 22% (65 aa)

LSEDNVIGRGGSGTVYKAMMRS-GELVAVKRLASCPVNSGKRSSGSRSSHDDFGFSAEVQTLGKIRHMNIVKLLGFCSNHETNLLVYEYMPN--GSLGEV
    ..||.|. |.|||.  .. |..||.|..                      .  |.| | | .| |||||.... . .   .| ||...  |.| ..
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-------------------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDY

LHGVGT--KACPVLDWETRYKVAVQAANGLCYLHHDCSPLIVHRDVKSNNILLDSNLRAHVADFGLAKLFQGSDKSESMSSVAGSYGYIAPEYAYTLKVN
..  |.  . .|    ..|. .. | ...| |.|      |.|||.|  |||||.  .  ..|||||...         ... |.  |.|||     . .
IKKRGRHGLRFPFPE-HARF-YMYQICCALEYCHSHG---IIHRDLKPENILLDE--HIKICDFGLARQL---------TTFCGTPWYMAPEVL---GYG

E-KSDIYSFGVVLLELVTGRRPIEPGYGDEIDIVKWVRKMIQTKDGVLAILDPRMGSTDLLPLHEVMLVLRVALLCSSDQPAE-------RPAM
  |.|..|.|..| |...|. | .    ..  . | ..                  | ... . . .|.   .   .  .  .        | .
KCKCDWWSCGCILYEMLCGYPPFP----QMQMMFKKIG------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase LRR8_j-1.AA RIPK 718-930 31 2.2e-38 128.42 In-house 1-230 (290) Show / Hide 
Range on Protein: 718-930
Range on HMM: 1-230/290
Sequence Identity: 31% (74 aa)

IGRGGSGTVYKAMMRSGELVAVKRLASCPVNSGKRSSGSRSSHDDFGFSAEVQTLGKIRHMNIVKLLGFCSNHET------NLLVYEYMPNGSLGEVLHG
.|.||.|.|.||  |.   ...|  . |.    .    . . .     . |.. . |.|. .||...|||   |         .| |||.|||| ..|| 
VGGGGFGEVFKARHRHWGDWVAKKCKPCKHCHTHM-DDQERMY----QKEEAKHMHKLRCEHIVPIYGFCQCEEWDCDCKLYGIVMEYMENGSLWHFLHT

VGT-KACPVLDWETRYKVAVQAANGLCYLHHDCSPLIVHRDVKSNNILLDSNLRAHVADFGLAKLFQGS----DKS-----ESMSSVA--GSYGYIAPEY
       |.. |  |    .. . | ||| |.  | | ||| |  |||.|.|. . .||||||.  ..|    |.       || |    |   |..|| 
KWPYQHHPDP-WPLRCRMIHEISCGMCYL-HSMNPPIIHRDLKPENILVDNNFHVKIADFGLATWMMWSHSHQDRCNQREVYSMKSKNRWGTLSYMPPEH

AY--TLKV----NEKSDIYSFGVVLLELVTGRRPIEP
      |     ..|.|.|||..|. |. |.. | |.
FRTDNKKPIKVVTPKYDVYSFAIVMWEVLTQKHPYED
Kinase LRR8_j-1.AA Dicty4 765-927 37 1.9e-37 122.6 In-house 45-216 (277) Show / Hide 
Range on Protein: 765-927
Range on HMM: 45-216/277
Sequence Identity: 37% (66 aa)

FSAEVQTLGKIRHMNIVKLLGFCS----NHETNLLVYEYMPNGSLGEVLHG------VGTKACPVLDWETRYK---VAVQAANGLCYLHHDCSPLIVHRD
| .||  ..|||| ||....| |     . .. . | |||| |.| ..||         .|    |||... .    |  || |. .||  | | |.|||
FRKEVHIMCKIRHPNICLFMGACTAPRSHPGKMCIVTEYMPKGNLYSLLHDKPSEQQQSIK----LDWPLIKRAMRMAFDAARGMNWLHC-CNPVIIHRD

VKSNNILLDSNLRAHVADFGLAKLFQ-GSDKSESMSSVAGSYGYIAPEYAYTLKVNEKSDIYSFGVVLLELVTGRRP
 || |.| | |.|. |.||||..... ..|..  .....|. .. |||       |||.| |||| || |..|.  |
LKSHNLLVDKNWRVKVCDFGLSQYMKKHEDHKDNQMTACGTPCWMAPEVMMHQPYNEKADVYSFGIVLWEILTRQEP
Kinase LRR8_j-1.AA TK 712-999 15 3.7e-36 118.16 In-house 1-486 (486) Show / Hide 
Range on Protein: 712-999
Range on HMM: 1-486/486
Sequence Identity: 15% (79 aa)

LSEDNVIGRGGSG---TVYKAMMRSG--------------------------ELVAVKRLASCPVNSGK-RSS-------GSRSSHDDFG-----FSAEV
.   ...|.|  |   .|||...|..                          . |||| | .   .| . .         |        |     . .| 
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDG--------GEDFLEEAEEM

QTLG--KIRHMNIVKLLGFCSNHET------------NLLVYEYMPNGS----LGEVLH--GVGTKACPV------------------------------
. .   . .| |||.|.| |. .|.             ..| ||||.|.    | . |.    ...  .                               
KMMCHSLGHHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNS

---------------------------------------LDWETRYKVAVQAANGLCYLHHD-CSPL---IVHRDVKSNNILLDSNLR-----------A
                                       |. ...   ..|.|.|. |||   |. .   .||||.   |.|...|..           .
PCPEEQDYDDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCE-FIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVC

HVADFGLAK-----LFQGSDKSESMSSVAGSYG---------------------------YIAPEYAY---------TLKVNEKSDIYSFGVVLLELVT-
 .|||||..     |    ....   .. . ..                           . |||            . |  .|||..||||.. |..| 
KIADFGLSRQGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTY

GRRPIEPGYGDEIDIV----KWVRKMIQT----------KDGVLAILDPRMGSTD------LLPLHEVMLVL-RVALLCSSDQPAERPAMRDVVQML
|. |  .|  ..  ..    . | .....          . |    . . .. .|      . | |.   .. .. . | . .|..|| .......|
GQEPYYGGMSNQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMH-PPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL
Kinase LRR8_j-1.AA STE 712-927 22 1.1e-34 119.91 In-house 1-267 (359) Show / Hide 
Range on Protein: 712-927
Range on HMM: 1-267/359
Sequence Identity: 22% (62 aa)

LSEDNVIGRGGSGTVYKAMMR----------------SGELVAVKRLASCPVNSGKRS---SGSRS-----SHDDFGFSAEVQTLGKIR--HMNIVKLLG
.    .||.|..||||||| .                .||..|.|..  .. |. . .   . . .     . .   .  |.... | .  | |||| .|
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKD-ENQEN-Q-ELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYG

FCSNH-------ETNLLVYEYMPNGSLGEVLHGVGTKACP---------VLDWETRYKVAVQAANG-LCYLHHDCSPLIVHRDVKSNNILLDSNLRAHVA
 . .        ..  .. |||..||| .... .. . .|         ... .   ....|   | | |||      |.|||.|. ||||     .  .
CYFKEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHH---IIHRDIKPANILL-----VKLC

DFGLAKLFQGS--------------DKSESMSSVAGSYGYIAPEYAYT------LKVNEKSDIYSFGVVLLELVTGRRP
|||... .. |              . ..   ...|.  . |||           . ..|.||.|.| ...|..||. |
DFGVCGQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPP
Kinase LRR8_j-1.AA Pkinase_Tyr 712-927 27 9.2e-32 108.19 Pfam 1-214 (270) Show / Hide 
Range on Protein: 712-927
Range on HMM: 1-214/270
Sequence Identity: 27% (64 aa)

LSEDNVIGRGGSGTVYKAMMR-----SGELVAVKRLASCPVNSGKRSSGSRSS---HDDFGFSAEVQTLGKI-RHMNIVKLLGFCS-NHET--NLLVYEY
.. . ..|.|  |.|||. ..      .  |||| |            |. ..   ..|| .. |.... .. .| |||.|.| |.   |    ..| ||
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLK----------EGAMHEQNCREDF-MR-EAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEY

MPNGSLGEVLHGVGTKACPVLDWETRYKVAVQAANGLCYLHHDCSPLIVHRDVKSNNILLDSNLRAHVADFGLAKLFQGSDKS-ESMSSVAGSYGYIAPE
||.|.| . |.       . |. ..  . ..| |.|. ||.      ..|||.   |.|...|. . ..|||||.. .  |    . ..        |||
MPHGDLLDYLRKHR-EDKQPLTMKDLLQMCWQIAKGMEYLESKN---CIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPE

YAYTLKVNEKSDIYSFGVVLLELVT-GRRP
   . | ..|||..||||.. |..| |. |
CINYGKFTTKSDVWSFGVLMWEIFTYGEQP
Kinase LRR8_j-1.AA Dicty4-Unclassified 712-927 32 1.6e-29 98.22 In-house 1-207 (263) Show / Hide 
Range on Protein: 712-927
Range on HMM: 1-207/263
Sequence Identity: 32% (73 aa)

LSEDNVIGRGGSGTVYKAMMRSGELVAVKRLASCPVNSGKRSSGSRSSHDDFGFSAEVQTLGKIRHMNIVKLLGFCSNH----ETNLLVYEYMPNGSLGE
.  |  ||.|    |.|   . |  |||| .     |..| .       |   | .||  || | | | ||. | | |      |   | | |. | | |
IQIDQFIGKGHFSKVHKGNWK-GKDVAVKKF-----NENKFKFREEMIQD---FKKEVEILGSIQHPNLVKCYGYCINPRSHKSTMCIVMEFMHKGNLFE

VLHGVGTKACPVLDWET--RYKVAVQAANGLCYLHHDCSPLIVHRDVKSNNILLDSNLRAHVADFGLAKLFQGSDKSESMSSVAGSYGYIAPEYAYTLKV
| |         .  .     |.|   | |. .||   .  ..|||.|| |||.| .  . .||||..      |    |  .||     .||       
VIHSKPSEQQQPIKLDDTLIIKYAFDIAQGMQHLH---TRNFIHRDIKSSNILMDKHFNIKIADFGISRVI---DFNFNMTTIAGTPKWESPECLMHESY

NEKSDIYSFGVVLLELVTGRRP
| |||.||....| ||.||  |
NQKSDVYSYAMMLYELATGDEP
Kinase LRR8_j-1.AA TyrKc 712-999 22 1.1e-24 89.2 SMART 1-280 (280) Show / Hide 
Range on Protein: 712-999
Range on HMM: 1-280/280
Sequence Identity: 22% (71 aa)

LSEDNVIGRGGSGTVYKAMMRSGELVAVKRLASCPVNSGKRSSGSRSSHDDFGFSAEVQTLGKI--RHMNIVKLLGFCSNH-------ETNLLVYEYMPN
.. . ..|.|  |.|||....  . |||| | ..                   |  | . . |.  .| |||.|.| |. .       |  ..| ||||.
ITLGKKLGEGAFGEVYKGTWK--IQVAVKMLKEDA---------------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPH

GSLGEVLHGVGTKACPVLDWETRYKVAVQAANGLCYLHHDCSPLIVHRDVKSNNILLDSNLRAHVADFGLAKLFQGSDKS----ESMSS----VA---GS
|.| . |.  . |    | ...  . ..|.|.|  |||.     ..|||    |.|...|... ..||||..     |..    .  ..     .     
GDLKDYLRKHRPK----LCMKDLLSFCWQIACGMEYLHSK---NCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLP

YGYIAPEYAYTLKVNEKSDIYSFGVVLLELVTGRRPIEPGYG------DEIDIVKWVRKMIQTKDGVLAILDPRMGSTDLLPLHEVMLVLRVALLCSSDQ
.   |||   . | ..|||..||||.. |. |  .  .| .|      . ......|..    .    .   | | .      .    . .. . |   .
IRWMAPECINYGKFTTKSDVWSFGVCMWEIFT--YGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDY--P-MSF-----VCCPDEMYQIMKQCWHED

PAERPAMRDVVQML
|..|| ...... .
PEDRPTFSEIHECF
Kinase LRR8_j-1.AA Dicty4 712-740 44 0.00297 6.9 In-house 1-28 (277) Show / Hide 
Range on Protein: 712-740
Range on HMM: 1-28/277
Sequence Identity: 44% (13 aa)

LSEDNVIGRGGSGTVYKAMMRSGELVAVK
.  .. ||.|. |.|||.  | |  ||||
INIEQRIGKGSFGEVYKGTWR-GKEVAVK
Kinase LRR8_j-1.AA Dicty4-Unclassified 981-999 36 0.008429 5.38 In-house 245-263 (263) Show / Hide 
Range on Protein: 981-999
Range on HMM: 245-263/263
Sequence Identity: 36% (7 aa)

CSSDQPAERPAMRDVVQML
| .. |  || | ...| |
CWHNDPNKRPTMNQIIQYL
Kinase LRR8_j-1.AA MLK 983-999 41 0.07822 2.3 In-house 275-291 (291) Show / Hide 
Range on Protein: 983-999
Range on HMM: 275-291/291
Sequence Identity: 41% (7 aa)

SDQPAERPAMRDVVQML
.. |..|| .| .|| |
NQDPHKRPSFRQIVQHL
Kinase LRR8_j-1.AA TKL 981-999 26 0.31275 0.2 In-house 346-364 (364) Show / Hide 
Range on Protein: 981-999
Range on HMM: 346-364/364
Sequence Identity: 26% (5 aa)

CSSDQPAERPAMRDVVQML
| .  | .|| . .... |
CWDHDPEKRPSFQEILKRL
Kinase LRR8_j-1.AA Pkinase_Tyr 985-999 26 0.713649 3.58 Pfam 256-270 (270) Show / Hide 
Range on Protein: 985-999
Range on HMM: 256-270/270
Sequence Identity: 26% (4 aa)

QPAERPAMRDVVQML
.|..|| .......|
DPEDRPTFSEIHEQL