Gene LRR11_c-1 (S.moellendorffii)

LRR11_c-1

Species: S.moellendorffii
Alias: LRR11_c-1
External Links:
Annotation:

Classification

Group: TKL
Family: IRAK
Subfamily: LRR11

Sequence

Name Sequence Type Origin Length Description Download
LRR11_c-1.AA Protein None 1066 None Fasta, JSON
LRR11_c-1.NA RNA None 3201 None Fasta, JSON
LRR11_c-1.kin_dom Protein Kinase Domain None 205 None Fasta, JSON

Protein domain

Protein domains of LRR11_c-1.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
LRRNT_2 LRR11_c-1.AA LRRNT_2 41-81 32 8.8e-11 37.93 Pfam 1-46 (46) Show / Hide 
Range on Protein: 41-81
Range on HMM: 1-46/46
Sequence Identity: 32% (15 aa)

KAEEEAALLDFRRSFAS-QP-GEVFDSWILS---RTCCAWRGIQCS
 ... .|||.|. |. .  | . |. ||  |    .|| |.|. |.
HNDDGQALLAFKSSLNDSDPHHGVLSSWNPSSSDSDCCSWTGVTCD
LRR_1 LRR11_c-1.AA LRR_1 100-122 37 3.35886 4.88 Pfam 1-26 (26) Show / Hide 
Range on Protein: 100-122
Range on HMM: 1-26/26
Sequence Identity: 37% (10 aa)

RVRVLSLPG-L--KLAGEIPPS-IARL
. ..|.| |    .| |.|||| .  |
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRR11_c-1.AA LRR_1 124-146 33 0.014933 13.22 Pfam 1-26 (26) Show / Hide 
Range on Protein: 124-146
Range on HMM: 1-26/26
Sequence Identity: 33% (9 aa)

ALEAVDLSA-N--QISGSIPAQ-LVSL
 |.  |||  |  ...|.||   . .|
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRR11_c-1.AA LRR_1 148-170 44 0.018744 12.87 Pfam 1-26 (26) Show / Hide 
Range on Protein: 148-170
Range on HMM: 1-26/26
Sequence Identity: 44% (12 aa)

HLKLLDLSA-N--NLSGALPPA-FRQG
.|. ||||  |  ||.| .||  | . 
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_TYP LRR11_c-1.AA LRR_TYP 146-169 45 0.053399 10.28 SMART 1-24 (24) Show / Hide 
Range on Protein: 146-169
Range on HMM: 1-24/24
Sequence Identity: 45% (11 aa)

LAHLKLLDLSANNLSGALPPAFRQ
| .|. |||| |.|.   | ||. 
LPNLRELDLSNNQLTHLPPGAFQG
LRR_1 LRR11_c-1.AA LRR_1 173-195 33 0.43156 8.04 Pfam 1-26 (26) Show / Hide 
Range on Protein: 173-195
Range on HMM: 1-26/26
Sequence Identity: 33% (9 aa)

AIVRLNLSD-N--LLEGPIPPM-LSSA
 . .|.||. |   |.| |||  . . 
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRR11_c-1.AA LRR_1 196-213 33 1.143058 6.54 Pfam 1-21 (26) Show / Hide 
Range on Protein: 196-213
Range on HMM: 1-21/26
Sequence Identity: 33% (7 aa)

SIESLDLSY-N--FFAGALPS
....||||. |   . | .|.
NLQHLDLSGCNCCNLTGHIPP
LRR_1 LRR11_c-1.AA LRR_1 220-239 20 27.333799 1.65 Pfam 4-26 (26) Show / Hide 
Range on Protein: 220-239
Range on HMM: 4-26/26
Sequence Identity: 20% (5 aa)

SLNVSN-N--ELSGPVLAA-LAHC
.|..|. |   |.| .    . ..
HLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRR11_c-1.AA LRR_1 296-318 37 0.05162 11.31 Pfam 1-26 (26) Show / Hide 
Range on Protein: 296-318
Range on HMM: 1-26/26
Sequence Identity: 37% (10 aa)

ALEELFLGY-N--SLGGEIPSS-ISNI
 |..| |.. |  .| |.||.| . | 
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_TYP LRR11_c-1.AA LRR_TYP 294-318 32 0.192873 5.71 SMART 1-24 (24) Show / Hide 
Range on Protein: 294-318
Range on HMM: 1-24/24
Sequence Identity: 32% (8 aa)

LAALEELFLGYNSLGGEIPSSISNI
| .|.|| |..| |  ..|. . . 
LPNLRELDLSNNQL-THLPPGAFQG
LRR_1 LRR11_c-1.AA LRR_1 272-294 33 7.811693 3.58 Pfam 1-26 (26) Show / Hide 
Range on Protein: 272-294
Range on HMM: 1-26/26
Sequence Identity: 33% (9 aa)

SIKLLDLST-N--AIPGGIPAA-IGRL
... ||||  |   . | ||   .  |
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRR11_c-1.AA LRR_1 345-367 37 1.1e-05 24.31 Pfam 1-26 (26) Show / Hide 
Range on Protein: 345-367
Range on HMM: 1-26/26
Sequence Identity: 37% (10 aa)

NLTELDLSY-N--RISGNIPSG-ISQC
||..||||. |  ...|.||.. . ..
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_TYP LRR11_c-1.AA LRR_TYP 343-367 52 0.000181 22.09 SMART 1-24 (24) Show / Hide 
Range on Protein: 343-367
Range on HMM: 1-24/24
Sequence Identity: 52% (13 aa)

LPNLTELDLSYNRISGNIPSGISQC
||||.|||||.|..   .|.|. |.
LPNLRELDLSNNQL-THLPPGAFQG
LRR_1 LRR11_c-1.AA LRR_1 320-343 29 1.010382 6.73 Pfam 1-26 (26) Show / Hide 
Range on Protein: 320-343
Range on HMM: 1-26/26
Sequence Identity: 29% (8 aa)

ALRILSLRN-N--DLGGEMAALDFSRL
 |..|.|.. |   | |.     |  |
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRR11_c-1.AA LRR_1 393-415 37 0.009296 13.95 Pfam 1-26 (26) Show / Hide 
Range on Protein: 393-415
Range on HMM: 1-26/26
Sequence Identity: 37% (10 aa)

KLETLSLSG-N--ELGGGIPAE-LQEC
.|..|.||| |   | | || . .  .
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRR11_c-1.AA LRR_1 369-391 37 0.036589 11.84 Pfam 1-26 (26) Show / Hide 
Range on Protein: 369-391
Range on HMM: 1-26/26
Sequence Identity: 37% (10 aa)

HLTSLTLGK-N--ELRGDIPSS-LGAL
.|..| |.  |   | |.||.| . .|
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_TYP LRR11_c-1.AA LRR_TYP 391-415 32 0.114361 7.57 SMART 1-24 (24) Show / Hide 
Range on Protein: 391-415
Range on HMM: 1-24/24
Sequence Identity: 32% (8 aa)

LRKLETLSLSGNELGGGIPAELQEC
|..|..|.||.| |   .|... ..
LPNLRELDLSNNQL-THLPPGAFQG
LRR_1 LRR11_c-1.AA LRR_1 417-440 25 15.243927 2.55 Pfam 1-26 (26) Show / Hide 
Range on Protein: 417-440
Range on HMM: 1-26/26
Sequence Identity: 25% (7 aa)

ALVMLVLSK-N--SFT-EPLPDRNVTGF
 |  | ||  |  ..| . .|..   ..
NLQHLDLSGCNCCNLTGH-IPPSCF-NL
LRR_1 LRR11_c-1.AA LRR_1 442-464 33 0.475713 7.89 Pfam 1-26 (26) Show / Hide 
Range on Protein: 442-464
Range on HMM: 1-26/26
Sequence Identity: 33% (9 aa)

NLQLLAIGN-A--GLSGSIPAW-IGNC
||| | ...     |.|.|| . . |.
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRR11_c-1.AA LRR_1 466-488 44 5.1e-05 21.97 Pfam 1-26 (26) Show / Hide 
Range on Protein: 466-488
Range on HMM: 1-26/26
Sequence Identity: 44% (12 aa)

KLQVLDLSW-N--RLVGEIPRW-IGAL
.||.||||  |  .|.|.|| . . .|
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRR11_c-1.AA LRR_1 490-512 40 0.000417 18.73 Pfam 1-26 (26) Show / Hide 
Range on Protein: 490-512
Range on HMM: 1-26/26
Sequence Identity: 40% (11 aa)

HLFYLDLSN-N--SFTGSIPPD-ILGI
.| .||||. |  ..||.|||. . . 
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_TYP LRR11_c-1.AA LRR_TYP 488-512 44 0.146857 6.68 SMART 1-24 (24) Show / Hide 
Range on Protein: 488-512
Range on HMM: 1-24/24
Sequence Identity: 44% (11 aa)

LDHLFYLDLSNNSFTGSIPPDILGI
| .|  |||||| .| ..||.... 
LPNLRELDLSNNQLT-HLPPGAFQG
LRR_1 LRR11_c-1.AA LRR_1 579-601 40 0.000983 17.41 Pfam 1-26 (26) Show / Hide 
Range on Protein: 579-601
Range on HMM: 1-26/26
Sequence Identity: 40% (11 aa)

KLVSLDLSN-N--KLVGSIPAC-LANA
.| .||||. |  .|.|.||   . | 
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_TYP LRR11_c-1.AA LRR_TYP 577-601 40 0.050339 10.49 SMART 1-24 (24) Show / Hide 
Range on Protein: 577-601
Range on HMM: 1-24/24
Sequence Identity: 40% (10 aa)

LRKLVSLDLSNNKLVGSIPACLANA
|..| .||||||.|  ..|. . . 
LPNLRELDLSNNQL-THLPPGAFQG
LRR_1 LRR11_c-1.AA LRR_1 561-577 42 1.824379 5.82 Pfam 7-26 (26) Show / Hide 
Range on Protein: 561-577
Range on HMM: 7-26/26
Sequence Identity: 42% (9 aa)

LAS-N--NLSGVIPLE-FGKL
| . |  ||.| || . | .|
LSGCNCCNLTGHIPPSCF-NL
LRR_1 LRR11_c-1.AA LRR_1 603-625 48 7.2e-05 21.43 Pfam 1-26 (26) Show / Hide 
Range on Protein: 603-625
Range on HMM: 1-26/26
Sequence Identity: 48% (13 aa)

DLESLDLSS-N--GLSGSIPPS-LVKL
 |..||||. |   |.|.|||| . .|
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRR11_c-1.AA LRR_1 627-651 28 20.679979 2.08 Pfam 1-26 (26) Show / Hide 
Range on Protein: 627-651
Range on HMM: 1-26/26
Sequence Identity: 28% (8 aa)

FLAAFNVSF-N--RLSGAIPSGNQFASF
 |   ..|  |  .|.| ||..  | ..
NLQHLDLSGCNCCNLTGHIPPS-CF-NL
Kinase LRR11_c-1.AA TKL 779-1051 21 2.5e-55 190.12 In-house 1-364 (364) Show / Hide 
Range on Protein: 779-1051
Range on HMM: 1-364/364
Sequence Identity: 21% (82 aa)

IGCGGFGLVFKANLPD---------GNVVAIKRLTSEDGGPQME-------------------------KEFDAELSTLGNITHPNLVSLEGYCR-----
|| |||| |.|...           |..||.|.. |..    ..                         ...  |.  . .. |||.|.. |||      
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

-LGMRD------RLLVYSYMENGSLDYWLHERSDGGSRLTWRHRLAILRETARGLEYLHR------GCNPHIVHRDIKSSNILLDGDLR-----------
   |.         .|. |...||| . ||          | .|. . ...|||..|||       .  | |.|||.||.|||.| ...           
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH----------WHQRCRWALDIARGMNYLHSMNPKWCT-KPPIIHRDLKSKNILVDENWTNVSNYMYNPNA

---AHVADFGLARLM----LPSDTHVTTE--------------LVGTLGYIPPEYAQSS----------------EASLRGDVYSFGVLVLEVLSRRRPV
   . ..||||.| |      .||  |.                .||... .||  . .                |.| . ||||||..  |.|.|.|  
DWCCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCR--

DACRRGGIRDLVPWVEGMQA------------TGRGIEIVDPLLLQNYSE----VDALEEMLRVLDVACYCVDSCPQRRPGIEEVVAWL
            |. . .               ... .   |..    ..    ..    . .. . .  | |. |. ||  .|.. .|
------------PYYDYPYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
Kinase LRR11_c-1.AA IRAK 773-1051 29 2.1e-52 180.41 In-house 1-317 (317) Show / Hide 
Range on Protein: 773-1051
Range on HMM: 1-317/317
Sequence Identity: 29% (96 aa)

FDATNIIGCGGFGLVFKANLPDGNV--VAIKRLTSEDG--GPQMEKEFDA---ELSTLGNITHPNLVSLEGYCRLGMRDRLLVYSYMENGSLDYWLHERS
|.. | || |||| |... . ...   .|.|.| ..      .....|..   || ..  . |||.|.| ||| ..  .  ||| || |||| . |. . 
FHKDNRIGEGGFGCVYRGQW-KNTTGIYAVKKLKEMADMSWNEHWQRFQQSYNELKVCCRCRHPNIVPLYGYC-TERQCHCLVYPYMPNGSLEDRLWCQD

DGGSR--LTWRHRLAILRETARGLEYLHR-G-CNPHIVHRDIKSSNILLDGDLRAHVADFGLARL-----MLPSDTH---VTTELVGTLGYIPPEYAQ--
  ..   |.|  |. |.  ||.|...||  . | |.| |.||||.||||| .. .  .||||.|       . . |     |  ..||. | |||.    
GQCPPKPLSWHQRCSICWGTACGIQFLHQNHPCTPII-HGDIKSANILLDQHFTPKICDFGLHRFGHPASHKEKQTYTCMMTSHVRGTTWYMPPEFIRDP

SSEASLRGDVYSFGVLVLEVLSRRRPVDACRRG--GIRDLVPWVEGMQATG---------------------RGIEIVDPLLLQNYSEVD-ALEEMLRVL
. . . . ||||||. .||||. .|.|.  |.   ...||.   | |. .|                     | . |.  ..    . .. ..|. .  .
QGQLTKKTDVYSFGIVLLEVLTGCRAVYDDRPEHYYLKDLC--EEIMEEWGHLDSCQSTLWVGVATDAWAAPRRMQIYEKFIDHRMPPCPPNMEKEM--C

DVACYCVDSCPQRRPGIEEVVAWL
..|| |.  .  ||. ...|.. |
QCACCCGHHRANRRCDMAWVMQQL
Kinase LRR11_c-1.AA Pkinase 773-975 24 2.5e-40 143.67 Pfam 1-209 (293) Show / Hide 
Range on Protein: 773-975
Range on HMM: 1-209/293
Sequence Identity: 24% (54 aa)

FDATNIIGCGGFGLVFKANLPDGNV-VAIKRLTSEDGGPQMEKEFDA--ELSTLGNITHPNLVSLEGYCRLGMRDRLLVYSYMENG----SLDYWLH-ER
.    .|| |.|| |.|.   . .  ||.|..  ..  ......     |.. . .. ||| | | ....   ..  .|  |.|.|    .|  ... .|
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFED-KDHIYMVMEYCEGGLYVMDLFDYISTWR

SDGGSRLTWRHRLAILRETARGLEYLHRGCNPHIVHRDIKSSNILLDGDLRA----HVADFGLARLM-LPSDTHVTTELVGTLGYIPPEYAQ-SSEASLR
. . . .....   ......|||||.|. .   |.|||.|..|||.| .       ...|||||... . ...  .| ..||..|..||  . ... . .
HGCFY-FSEWECKFYMYQILRGLEYCHS-M--GIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS--MTTFCGTPWYMAPEVIRGGQYYGPK

GDVYSFGVLVLEVLSRR
 |..|.|... |.|..|
VDMWSCGCILYEMLCGR
Kinase LRR11_c-1.AA S_TKc 773-1051 22 4e-34 120.62 SMART 1-231 (231) Show / Hide 
Range on Protein: 773-1051
Range on HMM: 1-231/231
Sequence Identity: 22% (66 aa)

FDATNIIGCGGFGLVFKANLPD-GNVVAIKRLTSEDGGPQMEKEFDAELSTLGNITHPNLVSLEGYCRLGMRDRLLVYSYMEN--GSLDYWLHERSDGGS
..  ..|| |.|| |.|.   . | .||||..          . .  |.. | .  |||.| | ....    .  .|  |...  |.|   ...|  .| 
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQD--DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

R--LTWRHRLAILRETARGLEYLHRGCNPHIVHRDIKSSNILLDGDLRAHVADFGLARLMLPSDTHVTTELVGTLGYIPPEYAQSSEASL-RGDVYSFGV
|  ..  |   ........|||.|   . .|.|||.| .|||||   .  ..||||||..        | ..||. |..||       .  . |..|.|.
RFPFPE-HARFYMYQICCALEYCH--SH-GIIHRDLKPENILLDE--HIKICDFGLARQL--------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGC

LVLEVLSRRRPVDACRRGGIRDLVPWVEGMQATGRGIEIVDPLLLQNYSEVDALEEMLRVLDVACYCVDSCPQRRPGIEEVVA---------WL
.. | |... | .        ..    . .                             ..|  . | .  |..||.. |. .         |.
ILYEMLCGYPPFP--------QMQMMFKKIG-------------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase LRR11_c-1.AA TKL-Unique 775-977 29 5e-34 117.45 In-house 1-233 (290) Show / Hide 
Range on Protein: 775-977
Range on HMM: 1-233/290
Sequence Identity: 29% (69 aa)

ATNIIGCGGFGLVFKANLPDGNVVAIKRLT-SEDGGPQMEKEFDAELSTLGNIT-HPNLVSLEGYCR---LGMRDRLLVYSYMENGSLDYWLH---ERS-
  | || ||.| |.|.  . |  ||||..   ||  ..|..||  |.... ..  |||.| . |||        .. .| .|.. |||.  ||     . 
FWNKIGEGGYGQVYKGKWR-GYPVAIKQFHPNEDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNNNNN

--DGGSRLTWRHRLAILRETARGLEYLHRGCNPHIVHRDIKSSNILLDGD-----LRAHVADFGLARLMLPSDTHVTTEL--------VGTLGYIPPEYA
     . |..  |. . .  |.|..|||.   | | |||.||||.|.| .     ... ..||||...   ...  ..|.        .|.. ...||  
NNNNNCKLNMQQRVKMAIDIAQGMYYLHHCEPP-IIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFRWMAPEVL

QS--SEASLRGDVYSFGVLVLEVLSRRR------P
 .  .  |   ||||||. . | ..| .      |
RMNFCQYSEKSDVYSFGIVLWEIATRKITKTYKKP
Kinase LRR11_c-1.AA TK 773-974 16 7e-34 110.39 In-house 1-390 (486) Show / Hide 
Range on Protein: 773-974
Range on HMM: 1-390/486
Sequence Identity: 16% (64 aa)

FDATNIIGCGGFG---LVFKANLPDGN--------------------------VVAIKRLTSEDGGPQMEKE---------------FDAELSTLGN--I
    . .| | ||    |.|. . ..|                           ||.| |...|.  |.|..               . .|.. . .   
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

THPNLVSLEGYCRLGMRD-----------RLLVYSYMENGS----LDYWLHERSDGGSR-----------------------------------------
 |||.|.| |.|  |               ..|  ||..|.    |. .|........                                          
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

-------------------------------LTWRHRLAILRETARGLEYLHRG----CNPHIVHRDIKSSNILLDGDLR-----------AHVADFG--
                               || ...| . .  |.|.||||.       ...||||.   |.|.. ...           . .||||  
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFI-QNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLS

------LARLMLPSDTHVTTELVGTLG-------------------------YIPPEYAQSSE---------ASLRGDVYSFGVLVLEVLSR
      ||| . ..|  ....  || .                         . .||  .. .          .   ||.|||||. |....
RQGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTY
Kinase LRR11_c-1.AA LRRK 773-979 25 6.6e-33 113.74 In-house 1-284 (351) Show / Hide 
Range on Protein: 773-979
Range on HMM: 1-284/351
Sequence Identity: 25% (75 aa)

FDATNIIGCGGFG-LVFKANLPD---------------------------GNVVAIKRLTS--------------------------------EDGGPQM
.   . || |||| .|..|.. .                           .. |||| ..                                 ... .  
LKIEEQIGRGGFGTFVYRAKWRGQPVHVCRMHQKMLQPYMYQGARNSYDMCQWVAIKKWNRDPMTIDNDCNNSNNNNNLNNNNSEQVEDMDQNHEDCCRA

EKEFDAELSTLGNITHPNLVSLEGYCRLGMRDRLLVYSYMENGSLDYWLHERSDGG-----SRLTWRHRLAILRETARGLEYLHRGCNPHIVHRDIKSSN
  ||  |.. . . .|||.||| |.|   .. . .|  |. .|.|.  ||...  |      ...|  .| |  . |.|.||||. .|| |.||| || |
FREFRHEVWIMSHLNHPNIVSLKGFC---IHPLCMVMEYAPHGDLYHFLHNKKQDGFHFMKAHISWMLKLKIALQIAKGMEYLHS-HNPPIIHRDLKSPN

ILL---D---------GDLRAHVADFGLARLMLPSDTH-VTTELVGTLGYIPPEYAQ---SSEASLRGDVYSFGVLVLEVLSRR-RPVD
|||   .          .  |..||||. | |  .... |.  .||. |.  ||  .    .| .   |.||||..  | |.|. .| |
ILLWSSPQNHSPNYPNAHVCAKIADFGISR-MFQCFHMGVAKGCVGNPGWMAPEIMRYNGEEEYTEKVDCYSFGMILWELLTRQHHPFD
Kinase LRR11_c-1.AA RIPK 779-977 31 3.8e-32 106.82 In-house 1-227 (290) Show / Hide 
Range on Protein: 779-977
Range on HMM: 1-227/290
Sequence Identity: 31% (72 aa)

IGCGGFGLVFKANLPD-GNVVAIKRLTSEDGG----PQMEKEFDAELSTLGNITHPNLVSLEGYCRLG--MRDRL---LVYSYMENGSLDYWLHERSD-G
.| |||| ||||   . | .||.|  ..         | ...   |   . .... . |...| |.      |     .|  |||||||   || ...  
VGGGGFGEVFKARHRHWGDWVAKKCKPCKHCHTHMDDQERMYQKEEAKHMHKLRCEHIVPIYGFCQCEEWDCDCKLYGIVMEYMENGSLWHFLHTKWPYQ

GSRLTWRHRLAILRETARGLEYLHRGCNPHIVHRDIKSSNILLDGDLRAHVADFGLARLMLPSDTHV----------TTELV--GTLGYIPPEYAQ--SS
   . |  |  .. |...|  ||| . || | ||| | .|||.|... . .||||||  |  |  |           .. .   ||| |.|||      .
HHPDPWPLRCRMIHEISCGMCYLH-SMNPPIIHRDLKPENILVDNNFHVKIADFGLATWMMWSHSHQDRCNQREVYSMKSKNRWGTLSYMPPEHFRTDNK

EA----SLRGDVYSFGVLVLEVLSRRRP
 .    .   |||||.... |||... |
KPIKVVTPKYDVYSFAIVMWEVLTQKHP
Kinase LRR11_c-1.AA MLK 773-977 26 1.8e-28 95.98 In-house 1-235 (291) Show / Hide 
Range on Protein: 773-977
Range on HMM: 1-235/291
Sequence Identity: 26% (62 aa)

FDATNIIGCGGFGLVFKANLPDGN----VVAIKRLTSEDGGPQME-----KEFDAELSTLGNITHPN----LVSLEGYCRLGMRDRLLVYSYMENGSLDY
..   .|| |.|| |.|..    .    .||.|| ...      .     ..|. |   |  . |||     . . | |     . ..|  |.|.|||  
IQFHEWIGSGSFGKVWKGRWRNKDIVAKIVAVKRVRARIF-DKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQPPCHFCIVMEYCEGGSLYN

WLHERSDGGS----------RLTWRHRLAILRETARGLEYLHRGCNPHIVHRDIKSSNILLD------GDLRAHVADFGLARLMLPSDTHVTTELVGTLG
 ||.......          . .  | . .    |||..|||    . |.|||.||.|||.|      ... . ..|||..| .  ..    .   ||. 
VLHGARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHSMAPKPIIHRDLKSHNILIDEICHDMHHGTLKICDFGTSRDWHQMC-TNMMSNAGTYA

YIPPEY---AQSSEASLRGDVYSFGVLVLEVLSRRRP
.  ||    ....  |   ||.|.||.  |.|.|. |
WMAPEVIQQFRCEKYSEKCDVWSWGVVLWEMLTREVP
Kinase LRR11_c-1.AA Pkinase_Tyr 773-974 26 6.2e-28 95.24 Pfam 1-210 (270) Show / Hide 
Range on Protein: 773-974
Range on HMM: 1-210/270
Sequence Identity: 26% (57 aa)

FDATNIIGCGGFGLVFKANLP-----DGNVVAIKRLTSEDGGPQM--EKEFDAELSTLGNI-THPNLVSLEGYCR-LGMR-DRLLVYSYMENGSLDYWLH
      .| | || |.|. .      ..  ||.| |  |.  ..    ..| .|.... ..  |||.|.| | |   |     ..|  ||..|.|.  |.
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR

ERSDGGSRLTWRHRLAILRETARGLEYLHRGCNPHIVHRDIKSSNILLDGDLRAHVADFGLARLMLPSDTH--VTTELVGTLGYIPPEYAQSSEASLRGD
...... .||  . | . .. |.|.|||..     ..|||.   |.|.. .. . ..||||||.. . |.   ....        .||  . .. .   |
KHREDKQPLTMKDLLQMCWQIAKGMEYLESKN---CIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECINYGKFTTKSD

VYSFGVLVLEVLSR
|.|||||  |....
VWSFGVLMWEIFTY
Kinase LRR11_c-1.AA STE 773-977 22 5e-25 85.39 In-house 1-267 (359) Show / Hide 
Range on Protein: 773-977
Range on HMM: 1-267/359
Sequence Identity: 22% (62 aa)

FDATNIIGCGGFGLVFKA--------NLPDGNV---------VAIKRLTSEDGGP---------------QMEKEFDAELSTLGNIT--HPNLVSLEGYC
..   .|| |.|| |.||        . . |.|         .|||..  |.  .               . ....  |.... .    ||| |   |..
WEGIEKIGKGAFGTVYKAMNHKNCNIH-KTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCY

RLG-----MRDRLLVYS-YMENGSLDYWLHERSDGGSRLT----------WRHRLAILRETARG-LEYLHRGCNPHIVHRDIKSSNILLDGDLRAHVADF
  .      .| | ..  ||..||||  ....   | .|.               .|.|.. .| |.|||.     |.|||||..||||     .  .||
FKEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHH---IIHRDIKPANILL-----VKLCDF

GLARLMLPS--------------DTH-VTTELVGTLGYIPPEYAQS------SEASLRGDVYSFGVLVLEVLSRRRP
|..  . .|              ..   .. .|||  .  ||  |       .. . . |..|.| ...| .  . |
GVCGQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPP
Kinase LRR11_c-1.AA Ciliate-E2 773-977 17 3.5e-24 79.91 In-house 1-295 (365) Show / Hide 
Range on Protein: 773-977
Range on HMM: 1-295/365
Sequence Identity: 17% (54 aa)

FDATNIIGCGGFGLVFKANL------------------------PDGNVVAIKRLTSEDGGPQMEKEFDAELSTLG-------------NITHPNLVSLE
..  ..|| |.|| |.|..                          ... .|.|..   .   .. |  . .. ..              .. |||.. . 
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQ--IEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMY

GYCRL-GMRDRLLVYSYMENGSLDYWLHER---------SDGGSRLTWRHRLAILRETAR---------------GLEYLHRGCNPHIVHRDIKSSNILL
 .          ||  | . |.| ... ..         . .  ..|..... | .. ..               .|||||   |  |.||||| .|||.
ECFQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEK-D-KYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNN--IIHRDIKPENILF

DGDLRAHVADFGLAR----------------LMLPSD--THVTTE-------------LVGTLGYIPPEYAQSSE---------ASLRGDVYSFGVLVLE
       ..||||..                ...     |..|.              ..||.|| .||  .. .          .   |..|.||.  |
-----IKIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYE

VLSRRRP
 |. ..|
MLFGKPP
Kinase LRR11_c-1.AA CZAK 773-977 28 2.1e-23 81.98 In-house 1-221 (279) Show / Hide 
Range on Protein: 773-977
Range on HMM: 1-221/279
Sequence Identity: 28% (64 aa)

FDATNIIGCGGFGLVFKANLPDGNVVAIKRLTSEDGGPQME----KEFDAELSTLGNITHPNLVSLEGYCRLGM-RDRLLVYSYMENGSLDYWLHERSDG
.     || | || | ||    | .|||| .. .      |      |. | | .    ||| |   | | ..   ..  |  .|. |||.  | ...  
LKFGQTIGQGFFGEVYKA-YWRGKDVAIKIIHRNQFRNKDENKEENMFQKEVSIMSKLCHPNCVQFLGACSEDGPNHHCIVMEWMGGGSLRRLLTDHY--

GSRLTW--RHRLAILRETARGLEYLHRGCNP-HIVHRDIKSSNILLDGDLR-------------AHVADFGLARLMLPSDTHVTTELVGTLGYIPPEYAQ
 . .      .. . .  |||  |||    |  |.|||  |.|||||  .              . ..|||| |.| .  .   |  .| | .  ||   
-FYHKQNPHLQWNMAIDIARGMNYLHDNWKPNPILHRDLSSRNILLDHSYTPKNPVVSSRQDIICKINDFGLSREMMEQPFEM-TQTMGCLCWMAPECFK

SSEASLRGDVYSFGVLVLEVLSRRRP
    .   |||||| .. ...  . |
GENYTEKVDVYSFGMILWCIITCDQP
Kinase LRR11_c-1.AA TyrKc 773-1051 20 2.5e-17 57.59 SMART 1-280 (280) Show / Hide 
Range on Protein: 773-1051
Range on HMM: 1-280/280
Sequence Identity: 20% (63 aa)

FDATNIIGCGGFGLVFKANLPDGNVVAIKRLTSEDGGPQMEKEFDAELSTLGNI--THPNLVSLEGYCRLGM------RDRLLVYSYMENGSLDYWLHER
     ..|.| || |.|. .     ||.| | ..      ...|  |.. . ..   |||.| | |.|. .          ..|  ||..|.|.  |...
ITLGKKLGEGAFGEVYKGTWK--IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKH

SDGGSRLTWRHRLAILRETARGLEYLHRGCNPHIVHRDIKSSNILLDGDLRAHVADFGLARLMLPS-------DTHVT-----TELVGTLGYIPPEYAQS
 .    |.... | .    |.| ||||.    ...|||.   |.|.. .... ..||||.|            |. ..     .  .  .   .||  . 
RPK---LCMKDLLSFCWQIACGMEYLHSK---NCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINY

SEASLRGDVYSFGVLVLEVLSR------------RRPVDACRRGGIRDLVPWVEG---MQATGRGIEIVDPLLLQNYSEVDALEEMLRVLDVACYCVDSC
.. .   ||.||||.  |....              . .. ..   ..  |  .    |                  . | . .|| ..      | .  
GKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMS-----------------F-VCCPDEMYQIM---KQCWHED

PQRRPGIEEVVAWL
|  ||  .|..  .
PEDRPTFSEIHECF