IRAK_Un_dd

Species: S.moellendorffii
Alias: IRAK_Un_dd
External Links:
Annotation:

Classification

Group: TKL
Family: IRAK
Subfamily: IRAK-Unclassified

Sequence

Name Sequence Type Origin Length Description Download
IRAK_Un_dd.AA Protein None 65 None Fasta, JSON
IRAK_Un_dd.NA RNA None 198 None Fasta, JSON
IRAK_Un_dd.kin_dom Protein Kinase Domain None 61 None Fasta, JSON

Protein domain

Protein domains of IRAK_Un_dd.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase IRAK_Un_dd.AA TKL 1-60 40 7.3e-18 60.92 In-house 118-175 (364) Show / Hide
Range on Protein: 1-60
Range on HMM: 118-175/364
Sequence Identity: 40% (27 aa)

EFVPNGTLAEHLQRERGDGLDWFTRVAIAADAAQGIAYLHSRS------PPIYHRDVKSTNILLDD
|..|.|.| ..|.        |  |. .| |.|.|..||||.       ||| ||| || |||.|.
EYCPGGSLLHYLH--------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDE

Kinase IRAK_Un_dd.AA LRRK 1-58 43 7.9e-18 59.64 In-house 135-199 (351) Show / Hide
Range on Protein: 1-58
Range on HMM: 135-199/351
Sequence Identity: 43% (28 aa)

EFVPNGTLAEHLQRERGDG-------LDWFTRVAIAADAAQGIAYLHSRSPPIYHRDVKSTNILL
|..|.|.| ..|. .. ||       ..| ..  || . | |..||||..||| ||| || ||||
EYAPHGDLYHFLHNKKQDGFHFMKAHISWMLKLKIALQIAKGMEYLHSHNPPIIHRDLKSPNILL

Kinase IRAK_Un_dd.AA TKL-Unique 1-62 40 5.6e-15 49.4 In-house 80-149 (290) Show / Hide
Range on Protein: 1-62
Range on HMM: 80-149/290
Sequence Identity: 40% (28 aa)

EFVPNGTLAEHLQR--------ERGDGLDWFTRVAIAADAAQGIAYLHSRSPPIYHRDVKSTNILLDDES
|..| |.| ..|..        ..   |..  || .| |.|||  |||...|||.||| ||.|.|.| .|
EYCPGGSLYDVLHQNNNNNNNNNNNCKLNMQQRVKMAIDIAQGMYYLHHCEPPIIHRDLKSSNFLVDNNS

Kinase IRAK_Un_dd.AA TKL-ciliate1 1-61 36 2e-14 45.8 In-house 79-141 (279) Show / Hide
Range on Protein: 1-61
Range on HMM: 79-141/279
Sequence Identity: 36% (23 aa)

EFVPNGTLAEHLQRERG--DGLDWFTRVAIAADAAQGIAYLHSRSPPIYHRDVKSTNILLDDE
|. . ||. . . | .     . |  |. .  | |||. |||.| .|. ||| |. |||.| .
EHCHKGTMFDICHRKHSQIYMIKWQHRMRWCKDIAQGMQYLHMRQNPLIHRDLKMQNILYDEP

Kinase IRAK_Un_dd.AA Dicty5 1-58 36 3.8e-14 45.09 In-house 79-137 (260) Show / Hide
Range on Protein: 1-58
Range on HMM: 79-137/260
Sequence Identity: 36% (22 aa)

EFVPNGTLAEHL-QRER--GDGLDWFTRVAIAADAAQGIAYLHSRSPPIYHRDVKSTNILL
|.. ||.| . | ....  |  . .|... .| |.||.. .||| .  | |||.|| |.|.
EYCHNGSLFNYLNDQRKTTGQPIAYFQQLHMAIDIAQSMRHLHSMN--IIHRDLKSMNFLI

Kinase IRAK_Un_dd.AA IRAK 1-60 40 5.4e-14 46.14 In-house 83-148 (317) Show / Hide
Range on Protein: 1-60
Range on HMM: 83-148/317
Sequence Identity: 40% (27 aa)

EFVPNGTLAEHLQRERG-DG---LDWFTRVAIAADAAQGIAYLHSRSP--PIYHRDVKSTNILLDD
.. |||.|   |.   | .    | | .|. |.  .| || .||. .|  || |.|.|| |||||.
PYMPNGSLEDRLWCQDGQCPPKPLSWHQRCSICWGTACGIQFLHQNHPCTPIIHGDIKSANILLDQ

Kinase IRAK_Un_dd.AA Dicty4 1-60 36 1.3e-13 41.96 In-house 82-149 (277) Show / Hide
Range on Protein: 1-60
Range on HMM: 82-149/277
Sequence Identity: 36% (25 aa)

EFVPNGTLAEHLQR-----ERGDGLDWFTRVA---IAADAAQGIAYLHSRSPPIYHRDVKSTNILLDD
|..| |.|.. |          . ||| .. .   .| |||.|...||.. | | ||| || |.| |.
EYMPKGNLYSLLHDKPSEQQQSIKLDWPLIKRAMRMAFDAARGMNWLHCCNPVIIHRDLKSHNLLVDK

Kinase IRAK_Un_dd.AA DRK 20-60 43 1.2e-12 39.25 In-house 95-135 (258) Show / Hide
Range on Protein: 20-60
Range on HMM: 95-135/258
Sequence Identity: 43% (18 aa)

LDWFTRVAIAADAAQGIAYLHSRSPPIYHRDVKSTNILLDD
.||  .  .. |.| |. |||.. | | ||| || | | |.
MDWPLMKQMMFDCAKGMIYLHCCNPIIIHRDLKSHNLLVDE

Kinase IRAK_Un_dd.AA LISK-DD1 20-60 53 5.6e-12 39.81 In-house 120-158 (290) Show / Hide
Range on Protein: 20-60
Range on HMM: 120-158/290
Sequence Identity: 53% (22 aa)

LDWFTRVAIAADAAQGIAYLHSRSPPIYHRDVKSTNILLDD
. |. || || | |.. |||||..  | ||| ||.|||.|.
IPWKLRVKIALDIACAMAYLHSKN--IIHRDLKSKNILVDE

Kinase IRAK_Un_dd.AA LISK 1-60 40 7.8e-12 34.53 In-house 77-136 (296) Show / Hide
Range on Protein: 1-60
Range on HMM: 77-136/296
Sequence Identity: 40% (25 aa)

EFVPNGTLAEHLQRE--RGDGLDWFTRVAIAADAAQGIAYLHSRSPPIYHRDVKSTNILLDD
|..  |.| . | ..  .   | |. || || | |.| .||||.   | ||| ||.|.|...
EYINGGDLHQYLKDMDKHKIPLPWPQRVKIALDIACGMSYLHSMN--IIHRDLKSKNCLVRE

Kinase IRAK_Un_dd.AA Pkinase 1-61 25 3.5e-11 40.64 Pfam 80-144 (293) Show / Hide
Range on Protein: 1-61
Range on HMM: 80-144/293
Sequence Identity: 25% (17 aa)

EFVPNG----TLAEHLQRERGDGL--DWFTRVAIAADAAQGIAYLHSRSPPIYHRDVKSTNILLDDE
|....|     |.......|. ..  .. .   ..   ..|..|.||.   | |||.|. |||.|..
EYCEGGLYVMDLFDYISTWRHGCFYFSEWECKFYMYQILRGLEYCHSM--GIIHRDLKPENILIDNN