Gene IRAK-Un_df (S.moellendorffii)

IRAK-Un_df

Species: S.moellendorffii
Alias: IRAK-Un_df
External Links:
Annotation:

Classification

Group: TKL
Family: IRAK
Subfamily: IRAK-Unclassified

Sequence

Name Sequence Type Origin Length Description Download
IRAK-Un_df.AA Protein None 574 None Fasta, JSON
IRAK-Un_df.NA RNA None 1725 None Fasta, JSON
IRAK-Un_df.kin_dom Protein Kinase Domain None 213 None Fasta, JSON

Protein domain

Protein domains of IRAK-Un_df.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase IRAK-Un_df.AA TKL 243-449 22 7.8e-52 178.53 In-house 1-284 (364) Show / Hide 
Range on Protein: 243-449
Range on HMM: 1-284/364
Sequence Identity: 22% (69 aa)

IGEGSYGHVYKGTLHR----------TNVAVKVLRHDSWQGPQEFEQEVRKLTRISKISNEHG----------------KIKVEVL---SRLHHPHIVLL
||.|..| ||||...           . ||||... .. .   . .||           .  .                . ..|..   |||.||.||..
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQEN---------ND-NNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQF

LG---------------GNPEKKCLVYEYLENGSLEDRLFCKDDSPPISCLTRYQIAVEVGTALLFLHKAKP-----QPIVLRDLKPSNILLDKNYN---
.|               |.. . |.|.|| ..|||...|             | ..| ..  .. .||  .|      ||. ||||..|||.|.|..   
MGYCCCPPCGCVCMHPVGPWGQLCIVMEYCPGGSLLHYLH---------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVS

-----------SKISDVGLARFMPGDE-----------------TSVRSTSPVGTFAYIDPEY----------------QREGSFNAKSDVFAFGIILLQ
            ||.| ||.||| ...                 .. .. ...||...  ||                 ....... |.||..|||.|  
NYMYNPNADWCCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWE

LLT
.||
ILT
Kinase IRAK-Un_df.AA IRAK 299-449 39 2.5e-36 126.32 In-house 54-219 (317) Show / Hide 
Range on Protein: 299-449
Range on HMM: 54-219/317
Sequence Identity: 39% (65 aa)

VEVLSRLHHPHIVLLLG--GNPEKKCLVYEYLENGSLEDRLFCKD-DSPP--ISCLTRYQIAVEVGTALLFLHKAKPQ-PIVLRDLKPSNILLDKNYNSK
..|..|..||.|| |.|    ... ||||.|. |||||||| | | . ||   |  .|  |.   . .. ||| . |  ||  .| |..|||||.. . |
LKVCCRCRHPNIVPLYGYCTERQCHCLVYPYMPNGSLEDRLWCQDGQCPPKPLSWHQRCSICWGTACGIQFLHQNHPCTPIIHGDIKSANILLDQHFTPK

ISDVGLARFM----PGDETSV---RSTSPVGTFAYIDPEYQR--EGSFNAKSDVFAFGIILLQLLT
|.| ||.||         ...   .    .|| .|  ||. |   |    |.||. ||| || .||
ICDFGLHRFGHPASHKEKQTYTCMMTSHVRGTTWYMPPEFIRDPQGQLTKKTDVYSFGIVLLEVLT
Kinase IRAK-Un_df.AA MLK 237-449 27 9.8e-35 117.96 In-house 1-231 (291) Show / Hide 
Range on Protein: 237-449
Range on HMM: 1-231/291
Sequence Identity: 27% (68 aa)

FSENNKIGEGSYGHVYKGTLHRTN-----VAVKVLRHDSWQGPQE-------FEQEVRKLTRISKISNEHGKIKVEVLSRLHHPHIVLLLGG---NPEKK
. .  .||.||.| |.||. . ..     ||||  |..     ..       ||.|.|.| ..|.  |              || |. ..|.   .| . 
IQFHEWIGSGSFGKVWKGRWRNKDIVAKIVAVKRVRARIF-DKSDTYCEQWDFEMECRHLRILSHPNN--------------HPCIIQFYGVCLQPPCHF

CLVYEYLENGSLEDRLFCKDDSPP-----------ISCLTRYQIAVEVGTALLFLHKAKPQPIVLRDLKPSNILLD------KNYNSKISDVGLARFMPG
|.| ||.|.||| . |  ... .            ..     ..|. .  .. .||. .|.||. ||||..|||.|      .. . ||.| |..|..  
CIVMEYCEGGSLYNVLHGARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHSMAPKPIIHRDLKSHNILIDEICHDMHHGTLKICDFGTSRDWHQ

D-ETSVRSTSPVGTFAYIDPEY--Q-REGSFNAKSDVFAFGIILLQLLT
  ..    .|  ||.|.  ||   | |.. .. |.||. .|..| ..||
MCTN---MMSNAGTYAWMAPEVIQQFRCEKYSEKCDVWSWGVVLWEMLT
Kinase IRAK-Un_df.AA LRRK 237-449 23 9.7e-34 116.73 In-house 1-277 (351) Show / Hide 
Range on Protein: 237-449
Range on HMM: 1-277/351
Sequence Identity: 23% (69 aa)

FSENNKIGEGSYG-HVYKGTLHR----------------------------TNVAVKVLRHD---------------------SWQGPQEFEQEVRKLTR
. ....||.|..|  ||.... .                            ..||.|..  |                     | |.    .|. . ..|
LKIEEQIGRGGFGTFVYRAKWRGQPVHVCRMHQKMLQPYMYQGARNSYDMCQWVAIKKWNRDPMTIDNDCNNSNNNNNLNNNNSEQVED-MDQNHEDCCR

I-SKISNEHGKIKVEVLSRLHHPHIVLLLGGNPEKKCLVYEYLENGSLEDRLFCKDDSP------PISCLTRYQIAVEVGTALLFLHKAKPQPIVLRDLK
. ..  .|     | ..|.|.||.|| |.|   .  |.| ||. .|.| ..|. |  ..       ||  ....||...  .. .||...| ||. ||||
AFREFRHE-----VWIMSHLNHPNIVSLKGFCIHPLCMVMEYAPHGDLYHFLHNKKQDGFHFMKAHISWMLKLKIALQIAKGMEYLHSHNP-PIIHRDLK

PSNILL---D---------KNYNSKISDVGLARFMPGDETSVRST---SPVGTFAYIDPEYQREG---SFNAKSDVFAFGIILLQLLT
. ||||   .          ... ||.| |. | |    ......     ||.. .  ||  |..   ... |.|...||.||  |||
SPNILLWSSPQNHSPNYPNAHVCAKIADFGISR-MF---QCFHMGVAKGCVGNPGWMAPEIMRYNGEEEYTEKVDCYSFGMILWELLT
Kinase IRAK-Un_df.AA Pkinase 237-453 27 1.7e-30 108.91 Pfam 1-211 (293) Show / Hide 
Range on Protein: 237-453
Range on HMM: 1-211/293
Sequence Identity: 27% (63 aa)

FSENNKIGEGSYGHVYKGTLHRTN--VAVKVLRHDSWQGPQEFEQEVRKLTRISKISNEHGKIKVEVLSRLHHPHIVLLLGGN--PEKKCLVYEYLENG-
.    |||.||.| |||.. . |.  ||||... .  . ... .. .|                .... ||.||.|| |..    . . ..| ||.|.| 
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKR-HEKSWKDQTHRRL-------------SEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGL

---SLEDRLFCKDDSPPI--SCLTRYQIAVEVGTALLFLHKAKPQPIVLRDLKPSNILLDKNYNS----KISDVGLARFMPGDETSVRSTSPVGTFAYID
   .| |..   ... ..  |  .   .. ..  .| ..|.     |. |||||.|||.|.|..     ||.| |||...     ..  |...||  |. 
YVMDLFDYIST-WRHGCFYFSEWECKFYMYQILRGLEYCHSM---GIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD-Y-NNS-MTTFCGTPWYMA

PEYQR-EGSFNAKSDVFAFGIILLQLLTATSP
||  |       |.|....|.|| ..|.   |
PEVIRGGQYYGPKVDMWSCGCILYEMLCGRPP
Kinase IRAK-Un_df.AA RIPK 243-453 27 2e-26 87.04 In-house 1-227 (290) Show / Hide 
Range on Protein: 243-453
Range on HMM: 1-227/290
Sequence Identity: 27% (67 aa)

IGEGSYGHVYKGT--LHRTNVAVKVLRHDSWQGPQEFEQEVRKLTRISKISNEHGKIKVEVLSRLHHPHIVLLLGGNPEK--------KCLVYEYLENGS
.| |. | |.| .   ... ||.|.      . .   .||. .. .  |. .           .| . ||| ..|   ..          .| || ||||
VGGGGFGEVFKARHRHWGDWVAKKCKPCKHCHTHM-DDQERMYQKEEAKHMH-----------KLRCEHIVPIYGFCQCEEWDCDCKLYGIVMEYMENGS

LEDRLFCKD--DSPPISCLTRYQIAVEVGTALLFLHKAKPQPIVLRDLKPSNILLDKNYNSKISDVGLARFMPGD--ET---------SVRSTSPVGTFA
|.. |  |     .|.    |  . .|.  .  .||  .| ||  |||||.|||.| |.. ||.| ||| .| .    .         | .|  . || .
LWHFLHTKWPYQHHPDPWPLRCRMIHEISCGMCYLHSMNP-PIIHRDLKPENILVDNNFHVKIADFGLATWMMWSHSHQDRCNQREVYSMKSKNRWGTLS

YIDPEYQREGSFNA------KSDVFAFGIILLQLLTATSP
|..||  |..  ..      |.||  |.|.. ..||   |
YMPPEHFRTDNKKPIKVVTPKYDVYSFAIVMWEVLTQKHP
Kinase IRAK-Un_df.AA TKL-Unique 299-444 29 1.2e-24 84.0 In-house 46-218 (290) Show / Hide 
Range on Protein: 299-444
Range on HMM: 46-218/290
Sequence Identity: 29% (52 aa)

VEVLSRLH-HPHIVLLLGGNP----EKK--CLVYEYLENGSLEDRLF-------CKDDSPPISCLTRYQIAVEVGTALLFLHKAKPQPIVLRDLKPSNIL
| ....|| || ||.. |.        .  |.| ||.. ||| | |           .. ... . |...|  .  .. .||  .|  |  ||||.||.|
VNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNNNNNNNNNNCKLNMQQRVKMAIDIAQGMYYLHHCEPP-IIHRDLKSSNFL

LDKN-----YNSKISDVGLARFMPGDETSVRS-------TSPVGTFAYIDPEYQRE--GSFNAKSDVFAFGIIL
.| |     .| ||.|.||..|   . ..  .       ....|.| .. ||  |     .. ||||..|||.|
VDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFRWMAPEVLRMNFCQYSEKSDVYSFGIVL
Kinase IRAK-Un_df.AA Dicty4 299-449 29 5.6e-24 77.0 In-house 49-212 (277) Show / Hide 
Range on Protein: 299-449
Range on HMM: 49-212/277
Sequence Identity: 29% (48 aa)

VEVLSRLHHPHIVLLLGG------NPEKKCLVYEYLENGSLEDRLFC------KDDSPPISCLTR-YQIAVEVGTALLFLHKAKPQPIVLRDLKPSNILL
|. .. . ||.|.|..|       .|.| | | ||.  |.|.  |        . .... .  .|  ..|  .   .  ||   |  |. ||||..|.| 
VHIMCKIRHPNICLFMGACTAPRSHPGKMCIVTEYMPKGNLYSLLHDKPSEQQQSIKLDWPLIKRAMRMAFDAARGMNWLHCCNPV-IIHRDLKSHNLLV

DKNYNSKISDVGLAR-FMPGDETSVRSTSPVGTFAYIDPEYQREGSFNAKSDVFAFGIILLQLLT
|||.. |..| ||.. . .. . .   ....|| ..  ||  .. ..| |.||. |||.| ..||
DKNWRVKVCDFGLSQYMKKHEDHKDNQMTACGTPCWMAPEVMMHQPYNEKADVYSFGIVLWEILT
Kinase IRAK-Un_df.AA CZAK 237-453 28 1.3e-23 82.66 In-house 1-221 (279) Show / Hide 
Range on Protein: 237-453
Range on HMM: 1-221/279
Sequence Identity: 28% (67 aa)

FSENNKIGEGSYGHVYKGTLHRTNVAVKVLRHDSWQGPQE-FEQEVRKLTRISKISNEHGKIKVEVLSRLHHPHIVLLLG----GNPEKKCLVYEYLENG
.     ||.| .| |||.    . ||.| .  ..     |  | ..          .|     | ..| | || .|  ||    ..|. .| | |. . |
LKFGQTIGQGFFGEVYKAYWRGKDVAIKIIHRNQFRNKDENKEENM--------FQKE-----VSIMSKLCHPNCVQFLGACSEDGPNHHCIVMEWMGGG

SLEDRLFCKDDSPPISC--LTRYQIAVEVGTALLFLHK-AKPQPIVLRDLKPSNILLDKNYN-------------SKISDVGLARFMPGDETSVRSTSPV
||  | .  | .  .      . ..|. .     .||   || ||. |||  .||||| .|               ||.| || | |   |     |. .
SL--RRLLTDHYFYHKQNPHLQWNMAIDIARGMNYLHDNWKPNPILHRDLSSRNILLDHSYTPKNPVVSSRQDIICKINDFGLSREM--MEQPFEMTQTM

GTFAYIDPEYQREGSFNAKSDVFAFGIILLQLLTATSP
|  ..  ||     ..  |.||. ||.||  ..|   |
GCLCWMAPECFKGENYTEKVDVYSFGMILWCIITCDQP
Kinase IRAK-Un_df.AA TK 237-449 18 2.6e-23 74.36 In-house 1-389 (486) Show / Hide 
Range on Protein: 237-449
Range on HMM: 1-389/486
Sequence Identity: 18% (72 aa)

FSENNKIGEGSYG---HVYKGTLHR---------------------------TNVAVKVLRHDSWQGPQEFEQ-EVRKLTRISKISNEHG------KIKV
    .|.||| .|    ||||....                           | ||||.|. .. . ..||.. | .   |      . |          
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHD--R-D----G-GEDFLEEAEEM

EVLS--RLHHPHIVLLLG----GNP----------EKKCLVYEYLENGS----LEDRLF-----------------------------------------
....   .|||.|| |.|    | |          |  ..| || ..|.    | | |                                          
KMMCHSLGHHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNS

------------CKDDSPPISCLTRYQ-------------------IAVEVGTALLFLHKAKP---QPIVLRDLKPSNILLDKNYN-----------SKI
             ||..||..    .|                   ... .  .. .||. .    | .| |||   |.|...|..            ||
PCPEEQDYDDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLLMCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKI

SDVG--------LARFMPGDETSVRSTSPVGT------------------------FAYIDPEYQREGS---------FNAKSDVFAFGIILLQLLT
.| |        ||| .. |.  .|..|. ..                        . .  ||  ...          |  ||||..||. .  ..|
ADFGLSRQGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFT
Kinase IRAK-Un_df.AA S_TKc 237-521 22 1.2e-19 72.57 SMART 1-231 (231) Show / Hide 
Range on Protein: 237-521
Range on HMM: 1-231/231
Sequence Identity: 22% (66 aa)

FSENNKIGEGSYGHVYKGTLHR--TNVAVKVLRHDSWQGPQEFEQEVRKLTRISKISNEHGKIKVEVLSRLHHPHIVLLLGGNP-EKKCLVYEYLEN--G
.   .|||.|..| |||.. ..    ||.|...                         || .  ...|.. |||.|| |..    .. ..| ||...  |
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-------------------------EHIRREIQILKK-HHPNIVKLYDVFQDDHLYMVMEYCDGDLG

SLEDRLFCKDDSPP---ISCLTRYQIAVEVGTALLFLHKAKPQPIVLRDLKPSNILLDKNYNSKISDVGLARFMPGDETSVRSTSPVGTFAYIDPEYQRE
.| |..  .   ..   ..  .   .. ..  || ..|. .   |. |||||.|||||.  . ||.| ||||..         |. .||  |. ||    
DLFDYIKKRGRHGLRFPFPE-HARFYMYQICCALEYCHSHG---IIHRDLKPENILLDE--HIKICDFGLARQL---------TTFCGTPWYMAPEVL--

GSFNA-KSDVFAFGIILLQLLTATSPVGIIHKVSTAVDQGHLMEILDTSAGEWPLAAATQLACIGLNCAEVQRKNRPELENVLQ-MLETMNHLFR
 ...  |.|. ..|.||  .|.   |           ..  .....             ..  .  .| ..  ..||    .||  .. ..| . 
-GYGKCKCDWWSCGCILYEMLCGYPPFP---------QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase IRAK-Un_df.AA TyrKc 237-513 22 1.8e-16 43.77 SMART 1-280 (280) Show / Hide 
Range on Protein: 237-513
Range on HMM: 1-280/280
Sequence Identity: 22% (69 aa)

FSENNKIGEGSYGHVYKGTLHRTNVAVKVLRHDSWQGPQEFEQEVRKLTRISKISNEHGKIKVEVLSRL--HHPHIVLLLGG--NP-------EKKCLVY
 . . |.||| .| |||||.  ..||||.|..|.                .  . .|      .....|  |||.|| |.|    .       |  ..| 
ITLGKKLGEGAFGEVYKGTWK-IQVAVKMLKEDA----------------REDFMRE-----ARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVM

EYLENGSLEDRL-FCKDDSPPISCLTRYQIAVEVGTALLFLHKAKPQPIVLRDLKPSNILLDKNYNSKISDVGLARFMPGD--------ETSVRS--TSP
|| ..|.| |.|  ....   ..  .  .... .     .||.    ... |||   |.|...|.  |||| ||.|.   |          ....   . 
EYMPHGDLKDYLRKHRPK---LCMKDLLSFCWQIACGMEYLHSK---NCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGK

-VGTFAYIDPEYQREGSFNAKSDVFAFGIIL--LQLLTATSPVG------IIHKVSTAVDQGHLMEILDT-----SAGEWPLAAATQLACIGLNCAEVQR
 .       ||  ..| |. ||||..||. .  .  . .. . |          |   |.||. |.. .      .       . . .  | . | . . 
TMLPIRWMAPECINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSF-----VCCPDEMYQIMKQCWHEDP

KNRPELENVLQML
..||  ... . .
EDRPTFSEIHECF
Kinase IRAK-Un_df.AA CAMK 373-453 23 2.4e-13 38.64 In-house 200-333 (425) Show / Hide 
Range on Protein: 373-453
Range on HMM: 200-333/425
Sequence Identity: 23% (32 aa)

IVLRDLKPSNILLDKN-----------------YNSKISDVGLARFMPGDETSV---------------------RSTSPVGTFAYID-PEYQR------
|| ||||| |||||.|                 .| ||.| |.|......| .                        . ..|| .|.  ||  .      
IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCN

--------EGSFNAKSDVFAFGIILLQLLTATSP
        .   . |.|. . |.||  .|. ..|
MQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPP
Kinase IRAK-Un_df.AA CAMK 242-338 16 4.4e-13 37.8 In-house 1-152 (425) Show / Hide 
Range on Protein: 242-338
Range on HMM: 1-152/425
Sequence Identity: 16% (27 aa)

KIGEGSYGHVYKGTLHRTN--------------VAVKVLRHD-------------------------SW---QGPQEFEQEVRKLTRISKISNEHGKIKV
..|.||.| |....  .|.              ||.|..  .                         .|   .  .....|.. . ....|.|       
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGN-------

EVLSRLHHPHIVLLLG--------------GNPEK--------KCLVY---EYLENGSLEDRLF
    .|.||.|. |.                . .|         ..|    || ..| | |.||
----KLDHPNIIKLYEVYEDPHYFKNTNDYET-SKQVFTKDKHMYMVMEIMEYCSGGELFDDLF
Kinase IRAK-Un_df.AA IRAK 237-267 45 1.6e-10 33.63 In-house 1-33 (317) Show / Hide 
Range on Protein: 237-267
Range on HMM: 1-33/317
Sequence Identity: 45% (15 aa)

FSENNKIGEGSYGHVYKGTLHRTN--VAVKVLR
|...|.|||| .| ||.| .. |   .||| |.
FHKDNRIGEGGFGCVYRGQWKNTTGIYAVKKLK
Kinase IRAK-Un_df.AA Pkinase_Tyr 237-288 27 1.9e-09 32.65 Pfam 1-62 (270) Show / Hide 
Range on Protein: 237-288
Range on HMM: 1-62/270
Sequence Identity: 27% (17 aa)

FSENNKIGEGSYGHVYKGTLH------RTNVAVKVLRHDSWQG---PQEFEQEVRKLTRI-S
 . . |.|||..|.|||||..      .. ||||.|.... .     ..| .|.. .. . .
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGH
Kinase IRAK-Un_df.AA TKL-Unique 241-282 44 2.1e-08 25.92 In-house 3-47 (290) Show / Hide 
Range on Protein: 241-282
Range on HMM: 3-47/290
Sequence Identity: 44% (20 aa)

NKIGEGSYGHVYKGTLHRTNVAVKVLRHDSWQGPQ---EFEQEVR
||||||.|| ||||. ... ||.|..   . . ..   ||| ||.
NKIGEGGYGQVYKGKWRGYPVAIKQFHPNEDSSNEMMQEFENEVN
Kinase IRAK-Un_df.AA Dicty4 237-266 50 5.1e-08 23.01 In-house 1-30 (277) Show / Hide 
Range on Protein: 237-266
Range on HMM: 1-30/277
Sequence Identity: 50% (15 aa)

FSENNKIGEGSYGHVYKGTLHRTNVAVKVL
    ..||.||.| |||||   . ||||.|
INIEQRIGKGSFGEVYKGTWRGKEVAVKKL
Kinase IRAK-Un_df.AA Pkinase_Tyr 299-442 28 1e-06 22.87 Pfam 54-202 (270) Show / Hide 
Range on Protein: 299-442
Range on HMM: 54-202/270
Sequence Identity: 28% (44 aa)

VEVLSRL-HHPHIVLLLGGNP--EKK---CLVYEYLENGSLEDRLFCK-DDSPPISCLTRYQIAVEVGTALLFLHKAKPQPIVLRDLKPSNILLDKNYNS
..... | |||.|| |.|     ..    ..| || ..|.| | |  . .| .|..  .  |.....  .. .|.  .   .. |||   |.|...|   
AKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKN---CIHRDLAARNCLVTENNVV

KISDVGLARFM-PGDET-SVRSTSPVGTFAYIDPEYQREGSFNAKSDVFAFGI
||.| |||| . . |.   .|. ..        ||  ..| |. |||| .||.
KICDFGLARDIYNDDYYYRKRGGGK-LPIKWMAPECINYGKFTTKSDVWSFGV
Kinase IRAK-Un_df.AA IRAK 473-513 17 0.067979 2.7 In-house 277-317 (317) Show / Hide 
Range on Protein: 473-513
Range on HMM: 277-317/317
Sequence Identity: 17% (7 aa)

LDTSAGEWPLAAATQLACIGLNCAEVQRKNRPELENVLQML
.|  .. .| . .  ...  . |..   ..|.. . |.| |
IDHRMPPCPPNMEKEMCQCACCCGHHRANRRCDMAWVMQQL